Activation of estrogen receptor-α by E2 or EGF induces temporally distinct patterns of large-scale chromatin modification and mRNA transcription

PLoS ONE

Volumn 3, Issue 5, 2008, Pages

  Berno, Valeria ^a   Amazit, Larbi ^a   Hinojos, Cruz ^a   Zhong, Jeannie ^a   Mancini, Maureen G ^a   Sharp, Zelton Dave ^b   Mancini, Michael A ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b University of Texas Health Science Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; ESTROGEN RECEPTOR ALPHA; MESSENGER RNA; PROLACTIN; ESTRADIOL;

ARTICLE; CELL ASSAY; CONTROLLED STUDY; HELA CELL; HORMONAL REGULATION; HORMONE ACTION; HORMONE DETERMINATION; HORMONE RESPONSE; HUMAN; HUMAN CELL; LIGAND BINDING; PROMOTER REGION; RNA TRANSCRIPTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; CHROMATIN; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM;

CHROMATIN; EPIDERMAL GROWTH FACTOR; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; HELA CELLS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 48649097511     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002286     Document Type: Article

References (51)

1. Smith CL, O'Malley BW (2004) Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr Rev 25: 45-71.
2. Ignar-Trowbridge DM, Pimentel M, Teng CT, Korach KS, McLachlan JA (1995) Cross talk between peptide growth factor and estrogen receptor signaling systems. Environ Health Perspect 103 Suppl 7: 35-38.
3. Kato S, Endoh H, Masuhiro Y, Kitamoto T, Uchiyama S, et al. (1995) Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 270: 1491-1494.
4. Levin ER (2003) Bidirectional signaling between the estrogen receptor and the epidermal growth factor receptor. Mol Endocrinol 17: 309-317.
5. Cenni B, Picard D (1999) Ligand-independent Activation of Steroid Receptors: New Roles for Old Players. Trends Endocrinol Metab 10: 41-46.
6. Smith CL (1998) Cross-talk between peptide growth factor and estrogen receptor signaling pathways. Biol Reprod 58: 627-632.
7. Gee JM, Hutcheson IR (2005) Understanding endocrine resistance: the critical need for sequential samples from clinical breast cancer and novel in vitro models. Breast Cancer Res 7: 187-189.
8. Britton DJ, Hutcheson IR, Knowlden JM, Barrow D, Giles M, et al. (2006) Bidirectional cross talk between ERalpha and EGFR signalling pathways regulates tamoxifen-resistant growth. Breast Cancer Res Treat 96: 131-146.
9. Osborne CK, Schiff R (2003) Growth factor receptor cross-talk with estrogen receptor as a mechanism for tamoxifen resistance in breast cancer. Breast 12: 362-367.
10. Osborne CK, Shou J, Massarwech S, Schiff R (2005) Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer. Clin Cancer Res 11: 865s-870s.
11. Citri A, Yarden Y (2006) EGF-ERBB signalling: towards the systems level. Nat Rev Mol Cell Biol 7: 505-516.
12. Ignar-Trowbridge DM, Teng CT, Rom KA, Parker MG, Korach KS, et al. (1993) Peptide growth factors elicit estrogen receptor-dependent transcriptional activation of an estrogen-responsive element. Mol Endocrinol 7: 992-998.
13. Curtis SW, Washburn T, Sewall C, DiAugustine R, Lindzey J, et al. (1996) Physiological coupling of growth factor and steroid receptor signaling pathways: estrogen receptor knockout mice lack estrogen-like response to epidermal growth factor. Proc. Natl Acad Sci U S A 93: 12626-12630.
14. Bunone G, Briand PA, Miksicek RJ, Picard D (1996) Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. EMBO J 15: 2174-2183.
15. Ignar-Trowbridge DM, Pimentel M, Parker MG, Mclachlan JA, Korach KS (1996) Peptide growth factor cross-talk with the estrogen receptor requires the A/B domain and occurs independently of protein kinase C or estradiol. Endocrinology 137: 1735-1744.
16. Lipfert L, Fisher JE, Wei N, Scafonas A, Su Q et al. (2006) Antagonist-induced, activation function-2-independent estrogen receptor alpha phosphorylation. Mol Endocrinol 20: 516-533.
17. Murphy L, Cherlet T, Adeyinka A, Niu Y, Snell L, et al. (2004) Phospho-serine-118 estrogen receptor-alpha detection in human breast tumors in vivo. Clin Cancer Res 10: 1354-1359.
18. Murphy LC, Niu Y, Snell L, Watson P (2004) Phospho-serine-118 estrogen receptor-alpha expression is associated with better disease outcome in women treated with tamoxifen. Clin Cancer Res 10: 5902-5906.
19. Sharp ZD, Mancini MG, Hinojos CA, Dai F, Berno V, et al. (2006) Estrogen-receptor-α exchange and chromatin dynamics are ligand- and domain-dependent. J Cell Sci 119: 4101-4116.
20. Manfroid I, Van de Weeredt C. Baudhuin A, Martial JA, Muller M (2005) EGF stimulates Pitl independent transcription of the human prolactin pituitary promoter in human breast cancer SK-BR-3 cells through its proximal AP-1 response element. Mol Cell Endocrinol 229: 127-139.
21. Berno V, Hinojos CA, Amazit L, Szafran AT, Mancini MA (2006) High-resolution, high-throughput microscopy analyses of nuclear receptor and coregulator function. Methods Enzymol 414: 188-210.
22. Voss TC, John S, Hager GL (2006) Single-cell analysis of glucocorticoid receptor action reveals that stochastic post-chromatin association mechanisms regulate ligand-specific transcription. Mol Endocrinol 20: 2641-2655.
23. El-Tanami MR, Green CD (1997) Two separate mechanisms for ligand-independent activation of the estrogen receptor. Mol Endocrinol 11: 928-937.
24. Kaem M, Elston TC, Blake WJ, Collins JJ (2005) Stochasticity in gene expression: from theories to phenotypes. Nat Rev Genet 6: 451-464.
25. Karpova TS, Kim MJ, Spriet C, Nalley K, Stasevich TJ, et al. (2008) Concurrent fast and slow cycling of a transcriptional activator at an endogenous promoter. Science 319: 466-469.
26. Takahashi T, Ohmichi M, Kawagoe J, Ohshima C, Doshida M, et al. (2005) Growth factors change nuclear distribution of estrogen receptor-alpha, via mitogen-activated protein kinase or phosphatidylinositol 3-kinase cascade in human breast cancer cell line. Endocrinology 146: 4082-4089.
27. Stenoien DL, Mancini MG, Patel K, Allegretto EA, Smith CL, et al. (2000) Subnuclear trafficking of estrogen receptor-α and steroid receptor coactivator-1. Mol Endocrinol 14: 518-534.
28. Stenoien DL, Nye AC, Mancini MG, Patel K, Dutertre M, et al. (2001) Ligand-mediated 3 assembly and real-time cellular dynamics of estrogen receptor α-coactivator complexes in living cells. Mol Cell Biol 21: 4404-4412.
29. Carter RE, Sorkin A (1998) Endocytosis of functional epidermal growth factor receptor-green fluorescent protein chimera. J Biol Chem 273: 35000-35007.
30. Chen WS, Lazar CS, Lund KA, Welsh JB, Chang CP, et al. (1989) Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation. Cell 59: 33-43.
31. Weitsman GE, Li L, Skliris GP, Davie JR, Ung K, et al. (2006) Estrogen receptor-alpha phosphorylated at Ser118 is present at the promoters of estrogen-regulated genes and is not altered due to HER-2 overexpression. Cancer Res 66: 10162-10170.
32. Metivier R, Penot G, Hubner MR, Reid G, Brand H, et al. (2003) Estrogen receptor-α directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter. Cell 115: 751-763.
33. Reid G, Hubner MR, Metivier R, Brand H, Denger S, et al. (2003) Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling. Mol Cell 11: 695-707.
34. Shang Y, Hu X, DiRenzo J, Lazar MA, Brown M (2000) Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell 103: 843-852.
35. Carrillo AJ, Sharp ZD, DePaolo LV (1987) Correlation of rat pituitary prolactin messenger ribonucleic acid and hormone content with serum levels during the estrogen-induced surge. Endocrinology 121: 1993-1999.
36. Voogt JL, Lee Y, Yang S, Arbogast L (2001) Regulation of prolactin secretion during pregnancy and lactation. Prog Brain Res 133: 173-185.
37. Bosisio D, Marazzi I, Agresti A, Shimizu N, Bianchi ME, et al. (2006) A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-kappaB-dependent gene activity. Embo J 25: 798-810.
38. Klokk TI, Kurys P, Elbi C, Nagaich AK, Hendarwanto A, et al. (2007) Ligand-specific dynamics of the androgen receptor at its response element in living cells. Mol Cell Biol 27: 1823-1843.
39. McNally JG, Muller WG, Walker D, Wolford R, Hager GL (2000) The glucocorticoid receptor: rapid exchange with regulatory sites in living cells. Science 287: 1262-1265.
40. Rayasam GV, Elbi C, Walker DA, Wolford R, Fletcher TM, et al. (2005) Ligand-specific dynamics of the progesterone receptor in living cells and during chromatin remodeling in vitro. Mol Cell Biol 25: 2406-2418.
41. Chubb JR, Trcek T, Shenoy SM, Singer RH (2006) Transcriptional pulsing of a developmental gene. Curr Biol 16: 1018-1025.
42. Ahmad K, Henikoff S (2002) Epigenetic consequences of nucleosome dynamics. Cell 111: 281-284.
43. Ali S, Metzger D, Bornert JM, Chambon P (1993) Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region. EMBO J 12: 1153-1160.
44. Gorski S, Misteli T (2005) Systems biology in the cell nucleus. J Cell Sci 118: 4083-4092.
45. Warren CM, Landgraf R (2006) Signaling through ERBB receptors: multiple layers of diversity and control. Cell Signal 18: 923-933.
46. Font de Mora J, Brown M (2000) AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor. Mol Cell Biol 20: 5041-5047.
47. Amazit L, Pasini L, Szafran AT, Berno V, Wu RC, et al. (2007) Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation. Mol Cell Biol 27: 6913-6932.
48. Shav-Tal Y, Darzacq X, Singer RH (2006) Gene expression within a dynamic nuclear landscape. EMBO J 25: 3469-3479.
49. Stenoien DL, Simeoni S, Sharp ZD, Mancini MA (2000) Subnuclear dynamics and transcription factor function. J Cell Biochem Suppl Suppl 35: 99-106.
50. Shopland RLS, Johnson CV, McNeil JA, Lawrence Tam JB (2002) Applications of RNA FISH for visualizing gene expression and nuclear architecture.: Oxford University Press ed. New York.
51. Fey EG, Ornelles DA, Penman S (1986) Association of RNA with the cytoskeleton and the nuclear matrix. J Cell Sci Suppl 5: 99-119.