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Volumn 17, Issue 1, 2014, Pages 163-177

Differential TIMP3 expression affects tumor progression and angiogenesis in melanomas through regulation of directionally persistent endothelial cell migration

Author keywords

Angiogenic potential; Directional endothelial cell migration; Melanoma; TIMP3

Indexed keywords

RECOMBINANT ENZYME; RECOMBINANT TISSUE INHIBITOR OF METALLOPROTEINASE 3; TISSUE INHIBITOR OF METALLOPROTEINASE 3; UNCLASSIFIED DRUG;

EID: 84892714116     PISSN: 09696970     EISSN: 15737209     Source Type: Journal    
DOI: 10.1007/s10456-013-9385-2     Document Type: Article
Times cited : (34)

References (49)
  • 1
    • 36849078591 scopus 로고    scopus 로고
    • Angiogenesis in melanoma
    • 1:CAS:528:DC%2BD1cXht1aqtr0%3D 2365306 18083379 10.1053/j.seminoncol. 2007.09.009
    • Mahabeleshwar GH, Byzova TV (2007) Angiogenesis in melanoma. Semin Oncol 34(6):555-565
    • (2007) Semin Oncol , vol.34 , Issue.6 , pp. 555-565
    • Mahabeleshwar, G.H.1    Byzova, T.V.2
  • 2
    • 0037805549 scopus 로고    scopus 로고
    • Basement membranes: Structure, assembly and role in tumour angiogenesis
    • 1:CAS:528:DC%2BD3sXktFOnsbw%3D 12778132 10.1038/nrc1094
    • Kalluri R (2003) Basement membranes: structure, assembly and role in tumour angiogenesis. Nat Rev Cancer 3(6):422-433
    • (2003) Nat Rev Cancer , vol.3 , Issue.6 , pp. 422-433
    • Kalluri, R.1
  • 3
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • 1:CAS:528:DyaK2MXjs1KnsLk%3D 7584949 10.1038/nm0195-27
    • Folkman J (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1(1):27-31
    • (1995) Nat Med , vol.1 , Issue.1 , pp. 27-31
    • Folkman, J.1
  • 4
    • 84975525035 scopus 로고
    • Seminars in medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis
    • 1:STN:280:DyaK28%2Fpt1ejuw%3D%3D 7491141 10.1056/NEJM199512283332608
    • Folkman J (1995) Seminars in medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis. N Engl J Med 333(26):1757-1763
    • (1995) N Engl J Med , vol.333 , Issue.26 , pp. 1757-1763
    • Folkman, J.1
  • 5
    • 0037699955 scopus 로고    scopus 로고
    • Angiogenesis in health and disease
    • 1:CAS:528:DC%2BD3sXktFOntbY%3D 12778163 10.1038/nm0603-653
    • Carmeliet P (2003) Angiogenesis in health and disease. Nat Med 9(6):653-660
    • (2003) Nat Med , vol.9 , Issue.6 , pp. 653-660
    • Carmeliet, P.1
  • 6
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • 1:CAS:528:DC%2BD3sXktFOnsb8%3D 12778130 10.1038/nrc1093
    • Bergers G, Benjamin LE (2003) Tumorigenesis and the angiogenic switch. Nat Rev Cancer 3(6):401-410
    • (2003) Nat Rev Cancer , vol.3 , Issue.6 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 7
    • 24144458264 scopus 로고    scopus 로고
    • A Rac switch regulates random versus directionally persistent cell migration
    • 1:CAS:528:DC%2BD2MXps1yqu7k%3D 16129786 10.1083/jcb.200503152
    • Pankov R, Endo Y, Even-Ram S, Araki M, Clark K, Cukierman E, Matsumoto K, Yamada KM (2005) A Rac switch regulates random versus directionally persistent cell migration. J Cell Biol 170(5):793-802
    • (2005) J Cell Biol , vol.170 , Issue.5 , pp. 793-802
    • Pankov, R.1    Endo, Y.2    Even-Ram, S.3    Araki, M.4    Clark, K.5    Cukierman, E.6    Matsumoto, K.7    Yamada, K.M.8
  • 8
    • 68049083547 scopus 로고    scopus 로고
    • Random versus directionally persistent cell migration
    • 1:CAS:528:DC%2BD1MXosFWhtrw%3D 2752299 19603038 10.1038/nrm2729
    • Petrie RJ, Doyle AD, Yamada KM (2009) Random versus directionally persistent cell migration. Nat Rev Mol Cell Biol 10(8):538-549
    • (2009) Nat Rev Mol Cell Biol , vol.10 , Issue.8 , pp. 538-549
    • Petrie, R.J.1    Doyle, A.D.2    Yamada, K.M.3
  • 9
    • 0034625002 scopus 로고    scopus 로고
    • Role of Rac in controlling the actin cytoskeleton and chemotaxis in motile cells
    • 1:CAS:528:DC%2BD3cXjsVWntL0%3D 10805781 10.1073/pnas.97.10.5225
    • Chung CY, Lee S, Briscoe C, Ellsworth C, Firtel RA (2000) Role of Rac in controlling the actin cytoskeleton and chemotaxis in motile cells. Proc Natl Acad Sci USA 97(10):5225-5230
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.10 , pp. 5225-5230
    • Chung, C.Y.1    Lee, S.2    Briscoe, C.3    Ellsworth, C.4    Firtel, R.A.5
  • 10
    • 8444221934 scopus 로고    scopus 로고
    • Localized Ras signaling at the leading edge regulates PI3 K, cell polarity, and directional cell movement
    • 1:CAS:528:DC%2BD2cXpvVCnsrY%3D 15534002 10.1083/jcb.200406177
    • Sasaki AT, Chun C, Takeda K, Firtel RA (2004) Localized Ras signaling at the leading edge regulates PI3 K, cell polarity, and directional cell movement. J Cell Biol 167(3):505-518
    • (2004) J Cell Biol , vol.167 , Issue.3 , pp. 505-518
    • Sasaki, A.T.1    Chun, C.2    Takeda, K.3    Firtel, R.A.4
  • 11
    • 0037205265 scopus 로고    scopus 로고
    • Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis
    • 1:CAS:528:DC%2BD38XksVGgs78%3D 12062104 10.1016/S0092-8674(02)00755-9
    • Funamoto S, Meili R, Lee S, Parry L, Firtel RA (2002) Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell 109(5):611-623
    • (2002) Cell , vol.109 , Issue.5 , pp. 611-623
    • Funamoto, S.1    Meili, R.2    Lee, S.3    Parry, L.4    Firtel, R.A.5
  • 12
    • 0023751380 scopus 로고
    • Fundulus deep cells: Directional migration in response to epithelial wounding
    • 1:STN:280:DyaL1czhtleksg%3D%3D 3410158 10.1016/0012-1606(88)90172-8
    • Fink RD, Trinkaus JP (1988) Fundulus deep cells: directional migration in response to epithelial wounding. Dev Biol 129(1):179-190
    • (1988) Dev Biol , vol.129 , Issue.1 , pp. 179-190
    • Fink, R.D.1    Trinkaus, J.P.2
  • 13
    • 33646541350 scopus 로고    scopus 로고
    • Novel functions of TIMPs in cell signaling
    • 1:CAS:528:DC%2BD28Xktlaksro%3D 16680576 10.1007/s10555-006-7893-x
    • Chirco R, Liu XW, Jung KK, Kim HR (2006) Novel functions of TIMPs in cell signaling. Cancer Metastasis Rev 25(1):99-113
    • (2006) Cancer Metastasis Rev , vol.25 , Issue.1 , pp. 99-113
    • Chirco, R.1    Liu, X.W.2    Jung, K.K.3    Kim, H.R.4
  • 14
    • 0025988402 scopus 로고
    • Growth stimulation of human keratinocytes by tissue inhibitor of metalloproteinases
    • 1:CAS:528:DyaK3MXmtVCntbo%3D 1940438 10.1111/1523-1747.ep12483956
    • Bertaux B, Hornebeck W, Eisen AZ, Dubertret L (1991) Growth stimulation of human keratinocytes by tissue inhibitor of metalloproteinases. J Invest Dermatol 97(4):679-685
    • (1991) J Invest Dermatol , vol.97 , Issue.4 , pp. 679-685
    • Bertaux, B.1    Hornebeck, W.2    Eisen, A.Z.3    Dubertret, L.4
  • 15
    • 0028132867 scopus 로고
    • Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2 (TIMP-2)
    • 1:CAS:528:DyaK2MXpsVClsw%3D%3D 7844157
    • Hayakawa T, Yamashita K, Ohuchi E, Shinagawa A (1994) Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2 (TIMP-2). J Cell Sci 107(Pt 9):2373-2379
    • (1994) J Cell Sci , vol.107 , Issue.PART 9 , pp. 2373-2379
    • Hayakawa, T.1    Yamashita, K.2    Ohuchi, E.3    Shinagawa, A.4
  • 16
    • 0032161747 scopus 로고    scopus 로고
    • Cell surface activation of progelatinase A (proMMP-2) and cell migration
    • 1:STN:280:DyaK1M%2Fgsl2nsQ%3D%3D 9791731 10.1038/cr.1998.18
    • Nagase H (1998) Cell surface activation of progelatinase A (proMMP-2) and cell migration. Cell Res 8(3):179-186
    • (1998) Cell Res , vol.8 , Issue.3 , pp. 179-186
    • Nagase, H.1
  • 17
    • 0041421283 scopus 로고    scopus 로고
    • Inhibition of fibroblast-induced angiogenic phenotype of cultured endothelial cells by the overexpression of tissue inhibitor of metalloproteinase (TIMP)-3
    • 1:CAS:528:DC%2BD3sXmsFaqur0%3D 12928593 10.1007/BF02256114
    • Ma DH, Chen JI, Zhang F, Hwang DG, Chen JK (2003) Inhibition of fibroblast-induced angiogenic phenotype of cultured endothelial cells by the overexpression of tissue inhibitor of metalloproteinase (TIMP)-3. J Biomed Sci 10(5):526-534
    • (2003) J Biomed Sci , vol.10 , Issue.5 , pp. 526-534
    • Ma, D.H.1    Chen, J.I.2    Zhang, F.3    Hwang, D.G.4    Chen, J.K.5
  • 18
    • 0032974030 scopus 로고    scopus 로고
    • Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3
    • 1:CAS:528:DyaK1MXitFGku78%3D 2362728 10188875 10.1038/sj.bjc.6690217
    • Baker AH, George SJ, Zaltsman AB, Murphy G, Newby AC (1999) Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3. Br J Cancer 79(9-10):1347-1355
    • (1999) Br J Cancer , vol.79 , Issue.9-10 , pp. 1347-1355
    • Baker, A.H.1    George, S.J.2    Zaltsman, A.B.3    Murphy, G.4    Newby, A.C.5
  • 19
    • 0032101072 scopus 로고    scopus 로고
    • Adenovirus-mediated gene delivery of tissue inhibitor of metalloproteinases-3 inhibits invasion and induces apoptosis in melanoma cells
    • 1:CAS:528:DyaK1cXjs12ru78%3D 9622064
    • Ahonen M, Baker AH, Kahari VM (1998) Adenovirus-mediated gene delivery of tissue inhibitor of metalloproteinases-3 inhibits invasion and induces apoptosis in melanoma cells. Cancer Res 58(11):2310-2315
    • (1998) Cancer Res , vol.58 , Issue.11 , pp. 2310-2315
    • Ahonen, M.1    Baker, A.H.2    Kahari, V.M.3
  • 20
    • 0032521142 scopus 로고    scopus 로고
    • Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis
    • 1:CAS:528:DyaK1cXitVWjtbc%3D 508704 9502791 10.1172/JCI1584
    • Baker AH, Zaltsman AB, George SJ, Newby AC (1998) Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis. J Clin Invest 101(6):1478-1487
    • (1998) J Clin Invest , vol.101 , Issue.6 , pp. 1478-1487
    • Baker, A.H.1    Zaltsman, A.B.2    George, S.J.3    Newby, A.C.4
  • 21
    • 0036839094 scopus 로고    scopus 로고
    • Enforced expression of tissue inhibitor of matrix metalloproteinase-3 affects functional capillary morphogenesis and inhibits tumor growth in a murine tumor model
    • 1:CAS:528:DC%2BD38XosVSitrc%3D 12384438 10.1182/blood.V100.9.3361
    • Spurbeck WW, Ng CY, Strom TS, Vanin EF, Davidoff AM (2002) Enforced expression of tissue inhibitor of matrix metalloproteinase-3 affects functional capillary morphogenesis and inhibits tumor growth in a murine tumor model. Blood 100(9):3361-3368
    • (2002) Blood , vol.100 , Issue.9 , pp. 3361-3368
    • Spurbeck, W.W.1    Ng, C.Y.2    Strom, T.S.3    Vanin, E.F.4    Davidoff, A.M.5
  • 22
    • 0028244447 scopus 로고
    • Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues
    • 1:CAS:528:DyaK2cXktVels7Y%3D 8132674
    • Leco KJ, Khokha R, Pavloff N, Hawkes SP, Edwards DR (1994) Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues. J Biol Chem 269(12):9352-9360
    • (1994) J Biol Chem , vol.269 , Issue.12 , pp. 9352-9360
    • Leco, K.J.1    Khokha, R.2    Pavloff, N.3    Hawkes, S.P.4    Edwards, D.R.5
  • 23
    • 0029019867 scopus 로고
    • The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family
    • 1:CAS:528:DyaK2MXmsVSisbw%3D 7782289 10.1074/jbc.270.24.14313
    • Apte SS, Olsen BR, Murphy G (1995) The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family. J Biol Chem 270(24):14313-14318
    • (1995) J Biol Chem , vol.270 , Issue.24 , pp. 14313-14318
    • Apte, S.S.1    Olsen, B.R.2    Murphy, G.3
  • 24
    • 0030323007 scopus 로고    scopus 로고
    • A review of tissue inhibitor of metalloproteinases-3 (TIMP-3) and experimental analysis of its effect on primary tumor growth
    • 1:CAS:528:DyaK2sXjsVGrsro%3D 9164653 10.1139/o96-090
    • Anand-Apte B, Bao L, Smith R, Iwata K, Olsen BR, Zetter B, Apte SS (1996) A review of tissue inhibitor of metalloproteinases-3 (TIMP-3) and experimental analysis of its effect on primary tumor growth. Biochem Cell Biol 74(6):853-862
    • (1996) Biochem Cell Biol , vol.74 , Issue.6 , pp. 853-862
    • Anand-Apte, B.1    Bao, L.2    Smith, R.3    Iwata, K.4    Olsen, B.R.5    Zetter, B.6    Apte, S.S.7
  • 25
    • 0037393850 scopus 로고    scopus 로고
    • A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): Inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2
    • 1:CAS:528:DC%2BD3sXisVOmu7k%3D 12652295 10.1038/nm846
    • Qi JH, Ebrahem Q, Moore N, Murphy G, Claesson-Welsh L, Bond M, Baker A, Anand-Apte B (2003) A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2. Nat Med 9(4):407-415
    • (2003) Nat Med , vol.9 , Issue.4 , pp. 407-415
    • Qi, J.H.1    Ebrahem, Q.2    Moore, N.3    Murphy, G.4    Claesson-Welsh, L.5    Bond, M.6    Baker, A.7    Anand-Apte, B.8
  • 29
    • 33751566963 scopus 로고    scopus 로고
    • Differential effects of matrix and growth factors on endothelial and fibroblast motility: Application of a modified cell migration assay
    • 16817234 10.1002/jcb.20994
    • van Horssen R, Galjart N, Rens JA, Eggermont AM, ten Hagen TL (2006) Differential effects of matrix and growth factors on endothelial and fibroblast motility: application of a modified cell migration assay. J Cell Biochem 99(6):1536-1552
    • (2006) J Cell Biochem , vol.99 , Issue.6 , pp. 1536-1552
    • Van Horssen, R.1    Galjart, N.2    Rens, J.A.3    Eggermont, A.M.4    Ten Hagen, T.L.5
  • 30
    • 0015822275 scopus 로고
    • Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria
    • 1:STN:280:DyaE2c%2FitFKgug%3D%3D 302542 4355998 10.1172/JCI107470
    • Jaffe EA, Nachman RL, Becker CG, Minick CR (1973) Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 52(11):2745-2756
    • (1973) J Clin Invest , vol.52 , Issue.11 , pp. 2745-2756
    • Jaffe, E.A.1    Nachman, R.L.2    Becker, C.G.3    Minick, C.R.4
  • 32
    • 0033558192 scopus 로고    scopus 로고
    • Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers
    • 1:CAS:528:DyaK1MXht1SjurY%3D 10029065
    • Bachman KE, Herman JG, Corn PG, Merlo A, Costello JF, Cavenee WK, Baylin SB, Graff JR (1999) Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers. Cancer Res 59(4):798-802
    • (1999) Cancer Res , vol.59 , Issue.4 , pp. 798-802
    • Bachman, K.E.1    Herman, J.G.2    Corn, P.G.3    Merlo, A.4    Costello, J.F.5    Cavenee, W.K.6    Baylin, S.B.7    Graff, J.R.8
  • 33
    • 0037341622 scopus 로고    scopus 로고
    • Frequent methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene in pancreatic endocrine tumors
    • 1:CAS:528:DC%2BD3sXit1ensb4%3D 12629131 10.1210/jc.2002-021027
    • Wild A, Ramaswamy A, Langer P, Celik I, Fendrich V, Chaloupka B, Simon B, Bartsch DK (2003) Frequent methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene in pancreatic endocrine tumors. J Clin Endocrinol Metab 88(3):1367-1373
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.3 , pp. 1367-1373
    • Wild, A.1    Ramaswamy, A.2    Langer, P.3    Celik, I.4    Fendrich, V.5    Chaloupka, B.6    Simon, B.7    Bartsch, D.K.8
  • 35
    • 49649125674 scopus 로고    scopus 로고
    • Identification of novel epigenetically modified genes in human melanoma via promoter methylation gene profiling
    • 1:CAS:528:DC%2BD1cXht1Kqt73M 18627528 10.1111/j.1755-148X.2008.00484.x
    • Liu S, Ren S, Howell P, Fodstad O, Riker AI (2008) Identification of novel epigenetically modified genes in human melanoma via promoter methylation gene profiling. Pigment Cell Melanoma Res 21(5):545-558
    • (2008) Pigment Cell Melanoma Res , vol.21 , Issue.5 , pp. 545-558
    • Liu, S.1    Ren, S.2    Howell, P.3    Fodstad, O.4    Riker, A.I.5
  • 36
    • 0034650795 scopus 로고    scopus 로고
    • Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: Possible involvement of TNFalpha and IL-1alpha
    • 1:CAS:528:DC%2BD3cXmsVCisg%3D%3D 10629075
    • Torisu H, Ono M, Kiryu H, Furue M, Ohmoto Y, Nakayama J, Nishioka Y, Sone S, Kuwano M (2000) Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: possible involvement of TNFalpha and IL-1alpha. Int J Cancer 85(2):182-188
    • (2000) Int J Cancer , vol.85 , Issue.2 , pp. 182-188
    • Torisu, H.1    Ono, M.2    Kiryu, H.3    Furue, M.4    Ohmoto, Y.5    Nakayama, J.6    Nishioka, Y.7    Sone, S.8    Kuwano, M.9
  • 37
    • 27644590410 scopus 로고    scopus 로고
    • Tumour-associated macrophage infiltration, neovascularization and aggressiveness in malignant melanoma: Role of monocyte chemotactic protein-1 and vascular endothelial growth factor-A
    • 1:CAS:528:DC%2BD2MXhtVantb3F 16179869 10.1097/00008390-200510000-00010
    • Varney ML, Johansson SL, Singh RK (2005) Tumour-associated macrophage infiltration, neovascularization and aggressiveness in malignant melanoma: role of monocyte chemotactic protein-1 and vascular endothelial growth factor-A. Melanoma Res 15(5):417-425
    • (2005) Melanoma Res , vol.15 , Issue.5 , pp. 417-425
    • Varney, M.L.1    Johansson, S.L.2    Singh, R.K.3
  • 38
    • 0038456130 scopus 로고    scopus 로고
    • Angiogenesis, lymphangiogenesis, and melanoma metastasis
    • 1:CAS:528:DC%2BD3sXkt12qurk%3D 12789293 10.1038/sj.onc.1206457
    • Streit M, Detmar M (2003) Angiogenesis, lymphangiogenesis, and melanoma metastasis. Oncogene 22(20):3172-3179
    • (2003) Oncogene , vol.22 , Issue.20 , pp. 3172-3179
    • Streit, M.1    Detmar, M.2
  • 39
    • 0031888022 scopus 로고    scopus 로고
    • An improved procedure to quantify tumour vascularity using true colour image analysis. Comparison with the manual hot-spot procedure in a human melanoma xenograft model
    • 9602703 10.1002/(SICI)1096-9896(199802)184:2<136: AID-PATH970>3.0. CO;2-9
    • van der Laak JA, Westphal JR, Schalkwijk LJ, Pahlplatz MM, Ruiter DJ, de Waal RM, de Wilde PC (1998) An improved procedure to quantify tumour vascularity using true colour image analysis. Comparison with the manual hot-spot procedure in a human melanoma xenograft model. J Pathol 184(2):136-143
    • (1998) J Pathol , vol.184 , Issue.2 , pp. 136-143
    • Van Der Laak, J.A.1    Westphal, J.R.2    Schalkwijk, L.J.3    Pahlplatz, M.M.4    Ruiter, D.J.5    De Waal, R.M.6    De Wilde, P.C.7
  • 40
    • 0032749387 scopus 로고    scopus 로고
    • Matrix metalloproteinases in human melanoma cell lines and xenografts: Increased expression of activated matrix metalloproteinase-2 (MMP-2) correlates with melanoma progression
    • 1:CAS:528:DyaK1MXnsFGgtLs%3D 2374291 10555745 10.1038/sj.bjc.6690763
    • Hofmann UB, Westphal JR, Waas ET, Zendman AJ, Cornelissen IM, Ruiter DJ, van Muijen GN (1999) Matrix metalloproteinases in human melanoma cell lines and xenografts: increased expression of activated matrix metalloproteinase-2 (MMP-2) correlates with melanoma progression. Br J Cancer 81(5):774-782
    • (1999) Br J Cancer , vol.81 , Issue.5 , pp. 774-782
    • Hofmann, U.B.1    Westphal, J.R.2    Waas, E.T.3    Zendman, A.J.4    Cornelissen, I.M.5    Ruiter, D.J.6    Van Muijen, G.N.7
  • 41
    • 0035116631 scopus 로고    scopus 로고
    • Tissue inhibitors of metalloproteases: Regulation and biological activities
    • 1:CAS:528:DC%2BD3MXhvFelsro%3D 11235986 10.1023/A:1006797522521
    • Fassina G, Ferrari N, Brigati C, Benelli R, Santi L, Noonan DM, Albini A (2000) Tissue inhibitors of metalloproteases: regulation and biological activities. Clin Exp Metastasis 18(2):111-120
    • (2000) Clin Exp Metastasis , vol.18 , Issue.2 , pp. 111-120
    • Fassina, G.1    Ferrari, N.2    Brigati, C.3    Benelli, R.4    Santi, L.5    Noonan, D.M.6    Albini, A.7
  • 42
    • 34547650992 scopus 로고    scopus 로고
    • Migration of culture-expanded human mesenchymal stem cells through bone marrow endothelium is regulated by matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-3
    • 17488654 10.3324/haematol.10475
    • De Becker A, Van Hummelen P, Bakkus M, Vande Broek I, De Wever J, De Waele M, Van Riet I (2007) Migration of culture-expanded human mesenchymal stem cells through bone marrow endothelium is regulated by matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-3. Haematologica 92(4):440-449
    • (2007) Haematologica , vol.92 , Issue.4 , pp. 440-449
    • De Becker, A.1    Van Hummelen, P.2    Bakkus, M.3    Vande Broek, I.4    De Wever, J.5    De Waele, M.6    Van Riet, I.7
  • 43
    • 78650424066 scopus 로고    scopus 로고
    • Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting
    • 1:CAS:528:DC%2BC3MXis1Kltg%3D%3D 21087457 10.1111/j.1742-4658.2010.07919. x
    • Gialeli C, Theocharis AD, Karamanos NK (2011) Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting. FEBS J 278(1):16-27
    • (2011) FEBS J , vol.278 , Issue.1 , pp. 16-27
    • Gialeli, C.1    Theocharis, A.D.2    Karamanos, N.K.3
  • 44
    • 84874571743 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinases-3 peptides inhibit angiogenesis and choroidal neovascularization in mice
    • 1:CAS:528:DC%2BC3sXktV2gs78%3D 3585964 23469166 10.1371/journal.pone. 0055667
    • Qi JH, Ebrahem Q, Ali M, Cutler A, Bell B, Prayson N, Sears J, Knauper V, Murphy G, Anand-Apte B (2013) Tissue inhibitor of metalloproteinases-3 peptides inhibit angiogenesis and choroidal neovascularization in mice. PLoS ONE 8(3):e55667
    • (2013) PLoS ONE , vol.8 , Issue.3 , pp. 55667
    • Qi, J.H.1    Ebrahem, Q.2    Ali, M.3    Cutler, A.4    Bell, B.5    Prayson, N.6    Sears, J.7    Knauper, V.8    Murphy, G.9    Anand-Apte, B.10
  • 45
    • 48849107531 scopus 로고    scopus 로고
    • Tissue inhibitors of metalloproteinases in cell signaling: Metalloproteinase-independent biological activities
    • Stetler-Stevenson WG (2008) Tissue inhibitors of metalloproteinases in cell signaling: metalloproteinase-independent biological activities. Sci Signal 1 (27): re6
    • (2008) Sci Signal , vol.1 , Issue.27 , pp. 6
    • Stetler-Stevenson, W.G.1
  • 46
    • 0345617112 scopus 로고    scopus 로고
    • Structural and functional uncoupling of the enzymatic and angiogenic inhibitory activities of tissue inhibitor of metalloproteinase-2 (TIMP-2): Loop 6 is a novel angiogenesis inhibitor
    • 1:CAS:528:DC%2BD3sXotFWgt7w%3D 12900406 10.1074/jbc.M306176200
    • Fernandez CA, Butterfield C, Jackson G, Moses MA (2003) Structural and functional uncoupling of the enzymatic and angiogenic inhibitory activities of tissue inhibitor of metalloproteinase-2 (TIMP-2): loop 6 is a novel angiogenesis inhibitor. J Biol Chem 278(42):40989-40995
    • (2003) J Biol Chem , vol.278 , Issue.42 , pp. 40989-40995
    • Fernandez, C.A.1    Butterfield, C.2    Jackson, G.3    Moses, M.A.4
  • 47
    • 0042197340 scopus 로고    scopus 로고
    • TIMP-2 mediated inhibition of angiogenesis: An MMP-independent mechanism
    • 1:CAS:528:DC%2BD3sXlvFCgu7k%3D 12887919 10.1016/S0092-8674(03)00551-8
    • Seo DW, Li H, Guedez L, Wingfield PT, Diaz T, Salloum R, Wei BY, Stetler-Stevenson WG (2003) TIMP-2 mediated inhibition of angiogenesis: an MMP-independent mechanism. Cell 114(2):171-180
    • (2003) Cell , vol.114 , Issue.2 , pp. 171-180
    • Seo, D.W.1    Li, H.2    Guedez, L.3    Wingfield, P.T.4    Diaz, T.5    Salloum, R.6    Wei, B.Y.7    Stetler-Stevenson, W.G.8
  • 48
    • 67651146533 scopus 로고    scopus 로고
    • Inhibition of vascular endothelial growth factor reduces angiogenesis and modulates immune cell infiltration of orthotopic breast cancer xenografts
    • 1:CAS:528:DC%2BD1MXosVynu78%3D 19567820 10.1158/1535-7163.MCT-09-0280
    • Roland CL, Dineen SP, Lynn KD, Sullivan LA, Dellinger MT, Sadegh L, Sullivan JP, Shames DS, Brekken RA (2009) Inhibition of vascular endothelial growth factor reduces angiogenesis and modulates immune cell infiltration of orthotopic breast cancer xenografts. Mol Cancer Ther 8(7):1761-1771
    • (2009) Mol Cancer Ther , vol.8 , Issue.7 , pp. 1761-1771
    • Roland, C.L.1    Dineen, S.P.2    Lynn, K.D.3    Sullivan, L.A.4    Dellinger, M.T.5    Sadegh, L.6    Sullivan, J.P.7    Shames, D.S.8    Brekken, R.A.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.