Inhibition of angiogenesis by tissue inhibitor of metalloproteinase-3

Investigative Ophthalmology and Visual Science

Volumn 38, Issue 5, 1997, Pages 817-823

  Anand Apte, Bela ^a,e   Pepper, Michael S ^b   Voest, Emile ^a   Montesano, Roberta ^b   Olsen, Bjorn ^c   Murphy, Gillian ^d   Apte, Suneel S ^c   Zetter, Bruce ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e LERNER RESEARCH INSTITUTE   (United States)

Author keywords

angiogenesis; extracellular matrix; Sorsby's fundus dystrophy; TIMP 3

Indexed keywords

STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE;

ANGIOGENESIS; ARTICLE; BLINDNESS; CHEMOTAXIS; CLINICAL FEATURE; DOMINANT INHERITANCE; DRUG EFFECT; GENE MUTATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RETINA MALFORMATION; SUBRETINAL NEOVASCULARIZATION; VASCULAR ENDOTHELIUM;

ALLANTOIS; ANIMALS; CELL DIVISION; CHEMOTAXIS; CHICK EMBRYO; CHORION; DIFFUSION CHAMBERS, CULTURE; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; FIBROBLAST GROWTH FACTOR 2; HUMANS; LYMPHOKINES; NEOVASCULARIZATION, PATHOLOGIC; PROTEASE INHIBITORS; PROTEINS; TISSUE INHIBITOR OF METALLOPROTEINASE-3; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0030901104     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Polkinghorne PJ, Capon MRC, Berninger T, Lyness AL, Sehmi K, Bird AC. Sorsby's fundus dystrophy. A clinical study. Ophthalmology. 1989;96:1763-1768.
2. Capon MRC, Marshall J, Krafft JI, Alexander RA, Hiscott PS, Bird AC. Sorsby's fundus dystrophy. A light and electron microscopic study. Ophthalmology. 1989;96:1769-1777.
3. Weber BH, Vogt G, Pruett RC, Stohr H, Felbor U. Mutations in the tissue inhibitor of metalloproteinase-3 (TIMP-3) in patients with Sorsby's fundus dystrophy. Nature Genetics. 1994;8:352-356
4. Jacobson SG, Cideciyan AV, Regunath G, Rodriguez FJ, Vandenburgh K, and Sheffield VV. Night blindness in Sorsby's fundus dystrophy is reversed by vitamin A. Nat Genet. 1995;11:27-32.
5. Peters AL, Greenberg J. Sorsby's fundus dystrophy. A South African family with a point mutation on the tissue inhibitor of metalloproteinase-3 gene on chromosome 22. Retina. 1995;15:480-485.
6. Pepper MS, Montesano R. Proteolytic balance and capillary morphogenesis. Cell Differentiation and Development. 1990;32:319-328.
7. Matrisian LM. The matrix degrading metalloproteinases. Bioessays. 1992;14:455-463.
8. Pavloff N, Staskus PW, Hawkes SP. A new inhibitor of metalloproteinases from chicken: Chimp-3. J Biol Chem. 1992;267:17321-17326.
9. Apte SS, Mattei M-G, Olsen BR. Cloning of the cDNA encoding human tissue inhibitor of metalloproteinase-3 (TIMP-3) and mapping of the TIMP-3 gene to chromosome 22. Genomics. 1994;19:86-90.
10. Murphy G. The regulation of connective tissue metalloproteinases by natural inhibitors. Transcript in AAS 35: Progress in Inflammation Research and Therapy. Basel: Birkhauser; 1991:69-76.
11. Apte SS, Olsen B, Murphy G. The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family. J Biol Chem. 1995;270:14313-14318.
12. Blenis J, Hawkes S. Transformation sensitive protein associated with the cell substratum of chicken embryo fibroblasts. Proc Natl Acad Sci USA. 1983;80:770-774.
13. Leco KJ, Khokha R, Pavloff N, Hawkes SP, Edwards DR. Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix associated protein with a distinctive pattern of expression in mouse cells and tissues. J Biol Chem. 1994;269:9352-9360.
14. Furie MB, Cramer EB, Naprstek BL, Silverstein SC. Cultured endothelial cell monolavers that restrict the transendothelial cell passage of macromolecules and electrical current. J Cell Biol. 1984; 98:1033-1041.
15. Murphy G, Houbrechts A, Cockett MI, Williamson RA, O'Shea M, Docherty AJ. The N terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitory activity. Biochemistry. 1991;30:8097-8102.
16. Willenbrock F, Crabbe T, Slocombe PM, et al. The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: A kinetic analysis of the inhibition of gelatinase A. Biochemistry. 1993;32:4330-4337.
17. Murphy G, Willenbrock F. Tissue Inhibitors of Matrix Metalloendopeptidases. Methods Enzymol. 1995;248:496-509.
18. Boyden SV. The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leukocytes. J Exp Med. 1962;115:453-466.
19. Montesano R, Orci L. Tumor promoting phorbol esters induce angiogenesis in vitro. Cell. 1985;42:469-477.
20. Pepper MS, Ferrara X, Orci L, Montesano R. Potent synergism between basic fibroblast growth factor and vascular endothelial growth factor in the induction of angiogenesis in vitro. Biochem Biophys Res Commun. 1992;189:824-831.
21. Nguyen M, Shing Y, Folkman J. Quantitation of angiogenesis and anti-angiogenesis in the chick embryo chorioallantoic membrane. Microvasc Res. 1994;47:31-40.
22. Pepper MS, Montesano R, Mandriota SJ, Orci L, Vassalli J-D. Angiogenesis: A paradigm for balanced extracellular proteolysis during cell migration and morphogenesis. Enzyme Protein. 1996;49:138-162.
23. Folkman J, Klagsbrun M. Angiogenic factors. Science. 1987;235:442-447.
24. Zetter BR. Cell motility in angiogenesis and tumor metastasis. Cancer Invest. 1988;8:669-671.
25. Vlodavsky I, Fuks Z, Ishai-Michaeli R, et al. Extracellular matrix-resident basic fibroblast growth factor: Implication for the control of angiogenesis. J Cell Biochem. 1991;45:167-176.
26. Park JE, Keller G-A, Ferrara N. The vascular endothelial growth factor (VEGF) isoforms: Differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix bound VEGF. Mol Biol Cell. 1993;4:1317-1326.
27. Apte SS, Hayashi K, Seldin M, Mattei MG, Hayashi M, Ofsen BR. Gene encoding a novel murine tissue inhibitor of metalloproteinases (TIMP), TIMP-3 is expressed in developing mouse epithelia, cartilage and muscle, and is located on mouse chromosome 10. Dev Dyn. 1994;200:177-197.
28. Takigawa MY, Nishida Y, Suzuki F, Kishi J, Yamashita K, Hayakawa T, Induction of angiogenesis in chick yolksac membrane by polyamines and its inhibition by tissue inhibitor of metalloproteinases (TIMP-1 and TTMP-2). Biochem Biophys Res Commun. 1990;171:1264-1271.
29. Johnson MD, Kim H-RC, Chesler L, Tsao-Wu G, Bouck N, Polverini P. Inhibition of angiogenesis by tissue inhibitor of metalloproteinase. J Cell Physiol. 1994;160:194-202.
30. Moses MA, Sudhalter J, Langer R. Identification of an inhibitor of neovascularization from cartilage. Science. 1990;248:1408-1410.
31. Murphy AN, Unsworth EJ, Stetler Stevenson WG. Tissue inhibitor of metalloproteinase-2 inhibits bFGF induced human microvascular endothelial cell proliferation. J Cell Physiol 1993;157:351-358.
32. Fisher C, Gilbertson-Beadling S, Powers EA, Petzold G, Poorman R, Mitchell MA. Interstitial collagenase is required for angiogenesis in vitro. Dev Biol. 1994; 162:499-510.
33. Horst W, Atkinson SJ, Butler GS, Smith B, Murphy G. The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. J Biol Chem. 1996;271:17119-17123.
34. Della NG, Campochiaro PA, Zack DJ. Localization of TIMP-3 mRNA expression to the retinal pigment epithelium. ARVO Abstracts. Invest Ophthalmol Vis Sci. 1996;15:S1143.
35. Fariss RN, Apte SS, Olsen BR, Iwata K, Milam AH. Tissue Inhibitor of Metalloproteinase-3 is a component of Bruch's membrane of the eye. Am J Pathol. 1997;150:323-328.