7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease

Neuropsychopharmacology

Volumn 39, Issue 3, 2014, Pages 638-650

  Zhang, Zhentao ^a,b   Liu, Xia ^a   Schroeder, Jason P ^a   Chan, Chi Bun ^a   Song, Mingke ^a   Yu, Shan Ping ^a   Weinshenker, David ^a   Ye, Keqiang ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

7,8 Dihydroxyflavone; Alzheimer's disease; neuroprotection; Synapse; TrkB

Indexed keywords

7,8 DIHYDROXYFLAVONE; AMYLOID BETA PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DENDRITE; GENE EXPRESSION; GENE MUTATION; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; MEMORY DISORDER; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SYNAPSE; SYNAPTIC TRANSMISSION; SYNAPTOGENESIS; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTIPSYCHOTIC AGENTS; APOPTOSIS; CELLS, CULTURED; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; FEMALE; FLAVONES; HIPPOCAMPUS; HUMANS; MAZE LEARNING; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; NEURONS; PLAQUE, AMYLOID; SYNAPSES;

EID: 84892680431     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2013.243     Document Type: Article

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