SRPK2 phosphorylates tau and mediates the cognitive defects in Alzheimer's disease

Journal of Neuroscience

Volumn 32, Issue 48, 2012, Pages 17262-17272

  Hong, Yi ^a   Chan, Chi Bun ^a   Kwon, Il Sun ^a   Li, Xuekun ^a   Song, Mingke ^a   Lee, Hyun Pil ^b   Liu, Xia ^a   Sompol, Pradoldej ^a   Jin, Peng ^a   Lee, Hyoung Gon ^b   Yu, Shan Ping ^a   Ye, Keqiang ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE; SERINE ARGININE PROTEIN KINASES 2; TAU PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTORADIOGRAPHY; COGNITIVE DEFECT; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FETUS; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MALE; MAZE TEST; MICROTUBULE ASSEMBLY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PHOSPHORYLATION; RNA SPLICING; WESTERN BLOTTING;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; DISEASE MODELS, ANIMAL; HUMANS; MAZE LEARNING; MICE; MICE, TRANSGENIC; NEURITES; NEURONAL PLASTICITY; NEURONS; PHOSPHORYLATION; PRESENILIN-1; PROTEIN-SERINE-THREONINE KINASES; TAU PROTEINS;

EID: 84870228676     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3300-12.2012     Document Type: Article

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