Hydrogen Peroxide Generated during Cellular Insulin Stimulation Is Integral to Activation of the Distal Insulin Signaling Cascade in 3T3-L1 Adipocytes

Journal of Biological Chemistry

Volumn 276, Issue 52, 2001, Pages 48662-48669

  Mahadev, Kalyankar ^a   Wu, Xiangdong ^a   Zilbering, Assaf ^a   Zhu, Li ^a   Lawrence, J Todd R ^b   Goldstein, Barry J ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BIOLOGICAL MEMBRANES; CELLS; ENZYMES; GLUCOSE; INSULIN;

PHOSPHORYLATION;

HYDROGEN PEROXIDE;

2 MORPHOLINO 8 PHENYLCHROMONE; DIPHENYLIODONIUM SALT; ENZYME INHIBITOR; GLUCOSE; GLUCOSE TRANSPORTER 4; HYDROGEN PEROXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; RECOMBINANT HUMAN INSULIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; WORTMANNIN; ANDROSTANE DERIVATIVE; CATION; CHROMONE DERIVATIVE; CULTURE MEDIA, SERUM FREE; GLUCOSE TRANSPORTER; GLUT 4 PROTEIN; GLUT-4 PROTEIN; INSULIN; MORPHOLINE DERIVATIVE; ONCOPROTEIN; OXIDIZING AGENT; PROTEIN TYROSINE PHOSPHATASE; PROTO ONCOGENE PROTEIN AKT; PROTO ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEIN AKT;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GLUCOSE TRANSPORT; HORMONE ACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; CELL FRACTIONATION; CELL LINE; CULTURE MEDIUM; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; METABOLISM; PHOSPHORYLATION; PROTEIN TRANSPORT;

ANIMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADIPOCYTES; ANDROSTADIENES; CELL FRACTIONATION; CELL LINE; CHROMONES; CULTURE MEDIA, SERUM-FREE; ENZYME ACTIVATION; ENZYME INHIBITORS; GLUCOSE; HUMAN; HYDROGEN PEROXIDE; INSULIN; MONOSACCHARIDE TRANSPORT PROTEINS; MORPHOLINES; ONIUM COMPOUNDS; OXIDANTS; PHOSPHORYLATION; PROTEIN TRANSPORT; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0035966052     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M105061200     Document Type: Article

References (53)

1. White, M. F. (1998) Recent Prog. Horm. Res. 53, 119-138
2. Patti, M. E., and Kahn, C. R. (1998) J. Basic Clin. Physiol. Pharmacol. 9, 89-109
3. White, M. F. (1998) Mol. Cell. Biochem. 182, 3-11
4. Sanchez-Margalet, V., Goldfine, I. D., Vlahos, C. J., and Sung, C. K. (1994) Biochem. Biophys. Res. Commun. 204, 446-452
5. Okada, T., Kawano, Y., Sakakibara, T., Hazeki, O., and Ui, M. (1994) J. Biol. Chem. 269, 3568-3573
6. Cheatham, B., Vlahos, C. J., Cheatham, L., Wang, L., Blenis, J., and Kahn, C. R. (1994) Mol. Cell. Biol. 14, 4902-4911
7. Brady, M. J., and Saltiel, A. R. (1999) J. Clin. Invest. 104, 675-676
8. Goldstein, B. J. (2000) in LeRoith, D., Olefsky, J. M., and Taylor, S. I. (eds) Diabetes Mellitus: A Fundamental and Clinical Text, pp. 206-217, Lippincott, Philadelphia
9. Zhang, Z. Y. (1998) Crit. Rev. Biochem. Mol. Biol. 33, 1-52
10. Claiborne, A., Yeh, J. I., Mallett, T. C., Luba, J., Crane, E. J., Charrier, V., and Parsonage, D. (1999) Biochemistry 38, 15407-15416
11. Barrett, W. C., DeGnore, J. P., Keng, Y. F., Zhang, Z. Y., Yim, M. B., and Chock, P. B. (1999) J. Biol. Chem. 274, 34543-34546
12. Mahadev, K., Zilbering, A., Zhu, L., and Goldstein, B. J. (2001) J. Biol. Chem. 276, 21938-21942
13. Herrlich, P., and Bohmer, F. D. (2000) Biochem. Pharmacol. 59, 35-41
14. Finkel, T. (2000) FEBS Lett. 476, 52-54
15. Griendling, K. K., and Ushio-Fukai, M. (2000) Regul. Pept. 91, 21-27
16. Bae, Y. S., Sung, J. Y., Kim, O. S., Kim, Y. J., Hur, K. C., Kazlauskas, A., and Rhee, S. G. (2000) J. Biol. Chem. 275, 10527-10531
17. Schmid, E., Hotz-Wagenblatt, A., Hack, V., and Droge, W. (1999) FASEB J. 13, 1491-1500
18. Li, Y., and Trush, M. A. (1998) Biochem. Biophys. Res. Commun. 253, 295-299
19. Gagnon, A., and Sorisky, A. (1998) Obes. Res. 6, 157-163
20. Bae, Y. S., Kang, S. W., Seo, M. S., Baines, I. C., Tekle, E., Chock, P. B., and Rhee, S. G. (1997) J. Biol. Chem. 272, 217-221
21. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
22. Goldstein, B. J., Bittner-Kowalczyk, A., White, M. F., and Harbeck, M. (2000) J. Biol. Chem. 275, 4283-4289
23. Hashimoto, N., Feener, E. P., Zhang, W. R., and Goldstein, B. J. (1992) J. Biol. Chem. 267, 13811-13814
24. Pike, L. J., Kuenzel, E. A., Casnellie, J. E., and Krebs, E. G. (1984) J. Biol. Chem. 259, 9913-9921
25. Tonks, N. K., Diltz, C. D., and Fischer, E. H. (1991) Methods Enzymol. 201, 442-451
26. Streuli, M., Krueger, N. X., Thai, T., Tang, M., and Saito, H. (1990) EMBO J. 9, 2399-2407
27. Laemmli, E. K. (1970) Nature 227, 680-685
28. Serunian, L. A., Auger, K. R., and Cantley, L. C. (1991) Methods Enzymol. 198, 78-87
29. Fingar, D. C., Hausdorff, S. F., Blenis, J., and Birnbaum, M. J. (1993) J. Biol. Chem. 268, 3005-3008
30. Hausdorff, S. F., Frangioni, J. V., and Birnbaum, M. J. (1994) J. Biol. Chem. 269, 21391-21394
31. Stuehr, D. J., Fasehun, O. A., Kwon, N. S., Gross, S. S., Gonzalez, J. A., Levi, R., and Nathan, C. F. (1991) FASEB J. 5, 98-103
32. Krieger-Brauer, H. I., Medda, P. K., and Kather, H. (1997) J. Biol. Chem. 272, 10135-10143
33. Krieger-Brauer, H. I., and Kather, H. (1992) J. Clin. Invest. 89, 1006-1013
34. Zhu, L., Zilbering, A., Wu, X., Mahadev, K., Joseph, J. I., Jabbour, S., Deeb, W., and Goldstein, B. J. (2001) FASEB J. 15, 1637-1639
35. Lavis, V. R., and Williams, R. H. (1970) J. Biol. Chem. 245, 23-31
36. Czech, M. P., and Fain, J. N. (1972) J. Biol. Chem. 247, 6218-6223
37. Czech, M. P., Lawrence, J. C. J., and Lynn, W. S. (1974) J. Biol. Chem. 249, 1001-1006
38. Blair, A. S., Hajduch, E., Litherland, G. J., and Hundal, H. S. (1999) J. Biol. Chem. 274, 36293-36299
39. Hansen, L. L., Ikeda, Y., Olsen, G. S., Busch, A. K., and Mosthaf, L. (1999) J. Biol. Chem. 274, 25078-25084
40. Rudich, A., Tirosh, A., Potashnik, R., Khamaisi, M., and Bashan, N. (1999) Diabetologia 42, 949-957
41. Tirosh, A., Potashnik, R., Bashan, N., and Rudich, A. (1999) J. Biol. Chem. 274, 10595-10602
42. May, J. M., and de Haen, C. (1979) J. Biol. Chem. 254, 9017-9021
43. May, J. M., and de Haen, C. (1979) J. Biol. Chem. 254, 2214-2220
44. Kennedy, B. P., and Ramachandran, C. (2000) Biochem. Pharmacol. 60, 877-883
45. Mooney, R. A., and Anderson, D. L. (1989) J. Biol. Chem. 264, 6850-6857
46. Shaw, M., Cohen, P., and Alessi, D. R. (1998) Biochem. J. 336, 1-246
47. Ushio-Fukai, M., Alexander, R. W., Akers, M., Yin, Q. Q., Fujio, Y., Walsh, K., and Griendling, K. K. (1999) J. Biol. Chem. 274, 22699-22704
48. Guy, G. R., Cairns, J., Ng, S. B., and Tan, Y. H. (1993) J. Biol. Chem. 268, 2141-2148
49. Moxham, C. M., and Malbon, C. C. (1996) Nature 379, 840-844
50. Chen, J. F., Guo, J. H., Moxham, C. M., Wang, H. Y., and Malbon, C. C. (1997) J. Mol. Med. 75, 283-289
51. Kim, J. R., Yoon, H. W., Kwon, K. S., Lee, S. R., and Rhee, S. G. (2000) Anal. Biochem. 283, 214-221
52. Pessin, J. E., and Saltiel, A. R. (2000) J. Clin. Invest. 106, 165-169
53. Ahmad, F., Li, P. M., Meyerovitch, J., and Goldstein, B. J. (1995) J. Biol. Chem. 270, 20503-20508