메뉴 건너뛰기




Volumn 289, Issue 3, 2014, Pages 1580-1591

Regulation of protease-activated receptor 1 signaling by the adaptor protein complex 2 and R4 subfamily of regulator of G protein signaling proteins

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR RESPONSE; DEPLETION ANALYSIS; DIFFERENT MECHANISMS; ECTOPIC EXPRESSIONS; G PROTEIN COUPLED RECEPTORS; PHOSPHOINOSITIDES; PROTEASE ACTIVATED RECEPTORS; SURFACE EXPRESSION;

EID: 84892634101     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.528273     Document Type: Article
Times cited : (14)

References (39)
  • 1
    • 28344436780 scopus 로고    scopus 로고
    • Protease-activated receptors in hemostasis, thrombosis and vascular biology
    • DOI 10.1111/j.1538-7836.2005.01377.x
    • Coughlin, S. R. (2005) Protease-activated receptors in hemostasis, thrombosis and vascular biology. J. Thromb. Haemost. 3, 1800-1814 (Pubitemid 41716567)
    • (2005) Journal of Thrombosis and Haemostasis , vol.3 , Issue.8 , pp. 1800-1814
    • Coughlin, S.R.1
  • 2
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • Vu, T. K., Hung, D. T., Wheaton, V. I., and Coughlin, S. R. (1991) Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64, 1057-1068 (Pubitemid 121001193)
    • (1991) Cell , vol.64 , Issue.6 , pp. 1057-1068
    • Vu, T.-K.H.1    Hung, D.T.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 3
    • 0028009801 scopus 로고
    • Inhibition of thrombin receptor signaling by aG protein-coupled receptor kinase. Functional specificity among G proteincoupled receptor kinases
    • Ishii, K., Chen, J., Ishii, M., Koch, W. J., Freedman, N. J., Lefkowitz, R. J., and Coughlin, S. R. (1994) Inhibition of thrombin receptor signaling by aG protein-coupled receptor kinase. Functional specificity among G proteincoupled receptor kinases. J. Biol. Chem. 269, 1125-1130
    • (1994) J. Biol. Chem. , vol.269 , pp. 1125-1130
    • Ishii, K.1    Chen, J.2    Ishii, M.3    Koch, W.J.4    Freedman, N.J.5    Lefkowitz, R.J.6    Coughlin, S.R.7
  • 4
    • 0037059795 scopus 로고    scopus 로고
    • β-arrestins regulate protease-activated receptor-1 desensitization but not internalization or down-regulation
    • DOI 10.1074/jbc.M109160200
    • Paing, M. M., Stutts, A. B., Kohout, T. A., Lefkowitz, R. J., and Trejo, J. (2002) β-arrestins regulate protease-activated receptor-1 desensitization but not internalization or down-regulation. J. Biol. Chem. 277, 1292-1300 (Pubitemid 34968882)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.2 , pp. 1292-1300
    • Paing, M.M.1    Stutts, A.B.2    Kohout, T.A.3    Lefkowitz, R.J.4    Trejo, J.5
  • 6
    • 1342325343 scopus 로고    scopus 로고
    • Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma cell invasion
    • DOI 10.1128/MCB.24.5.1990-1999.2004
    • Booden, M. A., Eckert, L. B., Der, C. J., and Trejo, J. (2004) Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma cell invasion. Mol. Cell Biol. 24, 1990-1999 (Pubitemid 38248939)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.5 , pp. 1990-1999
    • Booden, M.A.1    Eckert, L.B.2    Der, C.J.3    Trejo, J.4
  • 7
    • 47949089905 scopus 로고    scopus 로고
    • Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion
    • Arora, P., Cuevas, B. D., Russo, A., Johnson, G. L., and Trejo, J. (2008) Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion. Oncogene 27, 4434-4445
    • (2008) Oncogene , vol.27 , pp. 4434-4445
    • Arora, P.1    Cuevas, B.D.2    Russo, A.3    Johnson, G.L.4    Trejo, J.5
  • 8
    • 34247383616 scopus 로고    scopus 로고
    • Clathrin-dependent mechanisms of G protein-coupled receptor endocytosis
    • DOI 10.1111/j.1600-0854.2007.00551.x
    • Wolfe, B. L., and Trejo, J. (2007) Clathrin-dependent mechanisms of G protein-coupled receptor endocytosis. Traffic 8, 462-470 (Pubitemid 46638559)
    • (2007) Traffic , vol.8 , Issue.5 , pp. 462-470
    • Wolfe, B.L.1    Trejo, J.2
  • 9
    • 34249905192 scopus 로고    scopus 로고
    • Ubiquitination differentially regulates clathrin-dependent internalization of protease-activated receptor-1
    • DOI 10.1083/jcb.200610154
    • Wolfe, B. L., Marchese, A., and Trejo, J. (2007) Ubiquitination differentially regulates clathrin-dependent internalization of protease-activated receptor-1. J. Cell Biol. 177, 905-916 (Pubitemid 46873095)
    • (2007) Journal of Cell Biology , vol.177 , Issue.5 , pp. 905-916
    • Wolfe, B.L.1    Marchese, A.2    Trejo, J.3
  • 10
    • 81755171483 scopus 로고    scopus 로고
    • Adaptor protein complex-2 (AP-2) and epsin-1 mediate proteaseactivated receptor-1 internalization via phosphorylation- and ubiquitination-dependent sorting signals
    • Chen, B., Dores, M. R., Grimsey, N., Canto, I., Barker, B. L., and Trejo, J. (2011) Adaptor protein complex-2 (AP-2) and epsin-1 mediate proteaseactivated receptor-1 internalization via phosphorylation- and ubiquitination-dependent sorting signals. J. Biol. Chem. 286, 40760-40770
    • (2011) J. Biol. Chem. , vol.286 , pp. 40760-40770
    • Chen, B.1    Dores, M.R.2    Grimsey, N.3    Canto, I.4    Barker, B.L.5    Trejo, J.6
  • 11
    • 0038795645 scopus 로고    scopus 로고
    • Signals for sorting of transmembrane proteins to endosomes and lysosomes
    • DOI 10.1146/annurev.biochem.72.121801.161800
    • Bonifacino, J. S., and Traub, L. M. (2003) Signals for sorting of transmembrane proteins to endosomes and lysosomes. Annu. Rev. Biochem. 72, 395-447 (Pubitemid 36930451)
    • (2003) Annual Review of Biochemistry , vol.72 , pp. 395-447
    • Bonifacino, J.S.1    Traub, L.M.2
  • 13
    • 33644864081 scopus 로고    scopus 로고
    • Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization
    • Paing, M. M., Johnston, C. A., Siderovski, D. P., and Trejo, J. (2006) Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. Mol. Cell Biol. 28, 3231-3242
    • (2006) Mol. Cell Biol. , vol.28 , pp. 3231-3242
    • Paing, M.M.1    Johnston, C.A.2    Siderovski, D.P.3    Trejo, J.4
  • 14
    • 79960671811 scopus 로고    scopus 로고
    • Regulators of G-protein signaling and their Gα substrates. Promises and challenges in their use as drug discovery targets
    • Kimple, A. J., Bosch, D. E., Giguère, P. M., and Siderovski, D. P. (2011) Regulators of G-protein signaling and their Gα substrates. Promises and challenges in their use as drug discovery targets. Pharmacol. Rev. 63, 728-749
    • (2011) Pharmacol. Rev. , vol.63 , pp. 728-749
    • Kimple, A.J.1    Bosch, D.E.2    Giguère, P.M.3    Siderovski, D.P.4
  • 15
    • 4344635685 scopus 로고    scopus 로고
    • Application of RGS box proteins to evaluate G-protein selectivity in receptor-promoted signaling
    • DOI 10.1016/S0076-6879(04)89005-0, PII S0076687904890050
    • Hains, M. D., Siderovski, D. P., and Harden, T. K. (2004) Application of RGS bos proteins to evaluate G-protein selectivity in receptor-promoted signaling. Methods Enzymol. 389, 71-88 (Pubitemid 39119062)
    • (2004) Methods in Enzymology , vol.389 , pp. 71-88
    • Hains, M.D.1    Siderovski, D.P.2    Harden, T.K.3
  • 17
    • 0037067761 scopus 로고    scopus 로고
    • Receptor-selective effects of endogenous RGS3 and RGS5 to regulate mitogen-activated protein kinase activation in rat vascular smooth muscle cells
    • DOI 10.1074/jbc.M203802200
    • Wang, Q., Liu, M., Mullah, B., Siderovski, D. P., and Neubig, R. R. (2002) Receptor-selective effects of endogenous RGS3 and RGS5 to regulate mitogen-activated protein kinase activation in rat vascular smooth muscle cells. J. Biol. Chem. 277, 24949-24958 (Pubitemid 34951796)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.28 , pp. 24949-24958
    • Wang, Q.1    Liu, M.2    Mullah, B.3    Siderovski, D.P.4    Neubig, R.R.5
  • 18
    • 77956609549 scopus 로고    scopus 로고
    • RNA interference screen for RGS protein specificity at muscarinic and protease-activated receptors reveals bidirectional modulation of signaling
    • Laroche, G., Giguère, P. M., Roth, B. L., Trejo, J., and Siderovski, D. P. (2010) RNA interference screen for RGS protein specificity at muscarinic and protease-activated receptors reveals bidirectional modulation of signaling. Am. J. Physiol. Cell Physiol. 299, C654-664
    • (2010) Am. J. Physiol. Cell Physiol. , vol.299
    • Laroche, G.1    Giguère, P.M.2    Roth, B.L.3    Trejo, J.4    Siderovski, D.P.5
  • 19
    • 2542494843 scopus 로고    scopus 로고
    • A tyrosine-based sorting signal regulates intracellular trafficking of protease-activated reeeptor-1: Multiple regulatory mechanisms for agonist-induced G protein-coupled receptor internalization
    • DOI 10.1074/jbc.M401672200
    • Paing, M. M., Temple, B. R., and Trejo, J. (2004) A tyrosine-based sorting signal regulates intracellular trafficking of protease-activated receptor-1. Multiple regulatory mechanisms for agonist-induced G protein-coupled receptor internalization. J. Biol. Chem. 279, 21938-21947 (Pubitemid 38679384)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.21 , pp. 21938-21947
    • Paing, M.M.1    Temple, B.R.S.2    Trejo, J.3
  • 20
    • 0033593210 scopus 로고    scopus 로고
    • The cytoplasmic tails of proteaseactivated receptor-1 and substance P receptor specify sorting to lysosomes versus recycling
    • Trejo, J., and Coughlin, S. R. (1999) The cytoplasmic tails of proteaseactivated receptor-1 and substance P receptor specify sorting to lysosomes versus recycling. J. Biol. Chem. 274, 2216-2224
    • (1999) J. Biol. Chem. , vol.274 , pp. 2216-2224
    • Trejo, J.1    Coughlin, S.R.2
  • 21
    • 33947371974 scopus 로고    scopus 로고
    • N-terminal residues control proteasomal degradation of RGS2, RGS4, and RGS5 in human embryonic kidney 293 cells
    • DOI 10.1124/mol.106.029397
    • Bodenstein, J., Sunahara, R. K., and Neubig, R. R. (2007) N-terminal residues control proteasomal degradation of RGS2, RGS4, and RGS5 in human embryonic kidney 293 cells. Mol. Pharm. 71, 1040-1050 (Pubitemid 46457008)
    • (2007) Molecular Pharmacology , vol.71 , Issue.4 , pp. 1040-1050
    • Bodenstein, J.1    Sunahara, R.K.2    Neubig, R.R.3
  • 22
    • 65549087489 scopus 로고    scopus 로고
    • Caveolae are required for protease-selective signaling by protease-activated receptor-1
    • Russo, A., Soh, U. J., Paing, M. M., Arora, P., and Trejo, J. (2009) Caveolae are required for protease-selective signaling by protease-activated receptor-1. Proc. Natl. Acad. Sci. U.S.A. 106, 6393-6397
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 6393-6397
    • Russo, A.1    Soh, U.J.2    Paing, M.M.3    Arora, P.4    Trejo, J.5
  • 23
    • 1642368761 scopus 로고    scopus 로고
    • Termination of Protease-activated Receptor-1 Signaling by β-Arrestins Is Independent of Receptor Phosphorylation
    • DOI 10.1074/jbc.M310590200
    • Chen, C. H., Paing, M. M., and Trejo, J. (2004) Termination of proteaseactivated receptor-1 signaling by β-arrestins is independent of receptor phosphorylation. J. Biol. Chem. 279, 10020-10031 (Pubitemid 38372605)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.11 , pp. 10020-10031
    • Chen, C.-H.1    Paing, M.M.2    Trejo, J.3
  • 24
    • 84876578107 scopus 로고    scopus 로고
    • Transactivation of the PAR1-PAR2 heterodimer by thrombin elicits β-arrestin endosomal signaling
    • Lin, H., and Trejo, J. (2013) Transactivation of the PAR1-PAR2 heterodimer by thrombin elicits β-arrestin endosomal signaling. J. Biol. Chem. 288, 11203-11215
    • (2013) J. Biol. Chem. , vol.288 , pp. 11203-11215
    • Lin, H.1    Trejo, J.2
  • 25
    • 0030756508 scopus 로고    scopus 로고
    • Defective platelet activation in Gα(q)-deficient mice
    • DOI 10.1038/38284
    • Offermanns, S., Toombs, C. F., Hu, Y. H., and Simon, M. I. (1997) Defective platelet activation in G α (q) -deficient mice. Nature 389, 183-186 (Pubitemid 27400600)
    • (1997) Nature , vol.389 , Issue.6647 , pp. 183-186
    • Offermanns, S.1    Toombs, C.F.2    Hu, Y.-H.3    Simon, M.I.4
  • 27
    • 0036490096 scopus 로고    scopus 로고
    • Regulators of G-protein signalling as new central nervous system drug targets
    • Neubig, R. R., and Siderovski, D. P. (2002) Regulators of G-protein signalling as new central nervous system drug targets. Nat. Rev. Drug Discov. 1, 187-197 (Pubitemid 37361422)
    • (2002) Nature Reviews Drug Discovery , vol.1 , Issue.3 , pp. 187-197
    • Neubig, R.R.1    Siderovski, D.P.2
  • 29
    • 33646162635 scopus 로고    scopus 로고
    • GRKs and β-arrestins. Roles in receptor silencing, trafficking and signaling
    • Reiter, E., and Lefkowitz, R. J. (2006) GRKs and β-arrestins. Roles in receptor silencing, trafficking and signaling. Trends Endocrinol. Metab. 17, 159-165
    • (2006) Trends Endocrinol. Metab. , vol.17 , pp. 159-165
    • Reiter, E.1    Lefkowitz, R.J.2
  • 30
    • 69249135065 scopus 로고    scopus 로고
    • Tickets to ride. Selecting cargo for clathrin-regulated internalization
    • Traub, L. M. (2009) Tickets to ride. Selecting cargo for clathrin-regulated internalization. Nat. Rev. Mol. Cell Biol. 10, 583-596
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 583-596
    • Traub, L.M.1
  • 32
    • 84874384373 scopus 로고    scopus 로고
    • Clathrin and AP2 are required for PtdIns(4,5)P2-mediated formation of LRP6 signalosomes
    • Kim, I., Pan, W., Jones, S. A., Zhang, Y., Zhuang, X., and Wu, D. (2013) Clathrin and AP2 are required for PtdIns(4,5)P2-mediated formation of LRP6 signalosomes. J. Cell Biol. 200, 419-428
    • (2013) J. Cell Biol. , vol.200 , pp. 419-428
    • Kim, I.1    Pan, W.2    Jones, S.A.3    Zhang, Y.4    Zhuang, X.5    Wu, D.6
  • 33
    • 68549113039 scopus 로고    scopus 로고
    • Adaptor protein-2 interaction with arrestin regulates GPCR recycling and apoptosis
    • Wagener, B. M., Marjon, N. A., Revankar, C. M., and Prossnitz, E. R. (2009) Adaptor protein-2 interaction with arrestin regulates GPCR recycling and apoptosis. Traffic 10, 1286-1300
    • (2009) Traffic , vol.10 , pp. 1286-1300
    • Wagener, B.M.1    Marjon, N.A.2    Revankar, C.M.3    Prossnitz, E.R.4
  • 34
    • 84885736277 scopus 로고    scopus 로고
    • Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy
    • Tian, Y., Chang, J. C., Fan, E. Y., Flajolet, M., and Greengard, P. (2013) Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy. Proc. Natl. Acad. Sci. U.S.A. 110, 17071-17076
    • (2013) Proc. Natl. Acad. Sci. U.S.A , vol.110 , pp. 17071-17076
    • Tian, Y.1    Chang, J.C.2    Fan, E.Y.3    Flajolet, M.4    Greengard, P.5
  • 35
    • 13544255506 scopus 로고    scopus 로고
    • PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells
    • DOI 10.1016/j.cell.2004.12.018
    • Boire, A., Covic, L., Agarwal, A., Jacques, S., Sherifi, S., and Kuliopulos, A. (2005) PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells. Cell 120, 303-313 (Pubitemid 40222426)
    • (2005) Cell , vol.120 , Issue.3 , pp. 303-313
    • Boire, A.1    Covic, L.2    Agarwal, A.3    Jacques, S.4    Sherifi, S.5    Kuliopulos, A.6
  • 37
    • 84857520121 scopus 로고    scopus 로고
    • A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling
    • Ma, P., Cierniewska, A., Signarvic, R., Cieslak, M., Kong, H., Sinnamon, A. J., Neubig, R. R., Newman, D. K., Stalker, T. J., and Brass, L. F. (2012) A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling. Blood 119, 1935-1945
    • (2012) Blood , vol.119 , pp. 1935-1945
    • Ma, P.1    Cierniewska, A.2    Signarvic, R.3    Cieslak, M.4    Kong, H.5    Sinnamon, A.J.6    Neubig, R.R.7    Newman, D.K.8    Stalker, T.J.9    Brass, L.F.10
  • 38
    • 84860340490 scopus 로고    scopus 로고
    • Regulator of G-protein signaling 18 integrates activating and inhibitory signaling in platelets
    • Gegenbauer, K., Elia, G., Blanco-Fernandez, A., and Smolenski, A. (2012) Regulator of G-protein signaling 18 integrates activating and inhibitory signaling in platelets. Blood 119, 3799-3807
    • (2012) Blood , vol.119 , pp. 3799-3807
    • Gegenbauer, K.1    Elia, G.2    Blanco-Fernandez, A.3    Smolenski, A.4
  • 39
    • 0033605423 scopus 로고    scopus 로고
    • Internalization of the TXA2 receptor α and β isoforms
    • Parent, J. L., Labrecque, P., Orsini, M. J., and Benovic, J. L. (1999) Internalization of the TXA2 receptor α and β isoforms. J. Biol. Chem. 274, 8941-894
    • (1999) J. Biol. Chem. , vol.274 , pp. 8941-8894
    • Parent, J.L.1    Labrecque, P.2    Orsini, M.J.3    Benovic, J.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.