A tyrosine-based sorting signal regulates intracellular trafficking of protease-activated reeeptor-1: Multiple regulatory mechanisms for agonist-induced G protein-coupled receptor internalization

Journal of Biological Chemistry

Volumn 279, Issue 21, 2004, Pages 21938-21947

  Paing, May M ^a   Temple, Brenda R S ^a   Trejo, JoAnn ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEGRADATION; RECYCLING;

INTRACELLULAR TRAFFICKING; RECEPTOR SIGNALING;

BIOCHEMISTRY;

ALANINE; G PROTEIN COUPLED RECEPTOR; LEUCINE; MUTANT PROTEIN; PROTEINASE ACTIVATED RECEPTOR 1; THROMBIN; TYROSINE;

AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; COATED VESICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INTERNALIZATION; INTRACELLULAR TRANSPORT; LYSOSOME; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RECEPTOR UPREGULATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ALANINE; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CELL MEMBRANE; CLATHRIN; CYTOPLASM; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; GENES, DOMINANT; HELA CELLS; HUMANS; HYDROLYSIS; IMMUNOBLOTTING; LEUCINE; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHATIDYLINOSITOLS; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, PAR-1; RECEPTORS, G-PROTEIN-COUPLED; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; TYROSINE;

EID: 2542494843     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M401672200     Document Type: Article

References (28)

1. Krupnick, J. G., and Benovic, J. L. (1998) Annu. Rev. Pharmacol. Toxicol. 38, 289-319
2. Goodman, O. B., Jr., Krupnick, J. G., Santini, F., Gurevich, V. V., Penn, R. B., Gagnon, A. W., Keen, J. H., and Benovic, J. L. (1996) Nature 383, 447-450
3. Gray, J. A., and Roth, B. L. (2002) Science 297, 615-620
4. Vu, T.-K. H., Hung, D. T., Wheaton, V. I., and Coughlin, S. R. (1991) Cell 64, 1057-1068
5. Vu, T.-K. H., Wheaton, V. I., Hung, D. T., and Coughlin, S. R. (1991) Nature 353, 674-677
6. Chen, J., Ishii, M., Wang, L., Ishii, K., and Coughlin, S. R. (1994) J. Biol. Chem. 269, 16041-16045
7. Ishii, K., Hein, L., Kobilka, B., and Coughlin, S. R. (1993) J. Biol. Chem. 268, 9780-9786
8. Hein, L., Ishii, K., Coughlin, S. R., and Kobilka, B. K. (1994) J. Biol. Chem. 269, 27719-27726
9. Woolkalis, M. J., DeMelfi, T. J., Blanchard, N., Hoxie, J. A., and Brass, L. F. (1995) J. Biol. Chem. 270, 9868-9875
10. Shapiro, M. J., Trejo, J., Zeng, D., and Coughlin, S. R. (1996) J. Biol. Chem. 271, 32874-32880
11. Trejo, J., and Coughlin, S. R. (1999) J. Biol. Chem. 274, 2216-2224
12. Shapiro, M. J., and Coughlin, S. R. (1998) J. Biol. Chem. 273, 29009-29014
13. Paing, M. M., Stutts, A. B., Kohout, T. A., Lefkowitz, R. J., and Trejo, J. (2002) J. Biol. Chem. 277, 1292-1300
14. Chen, C. H., Paing, M. M., and Trejo, J. (2004) J. Biol. Chem. 279, 10020-10031
15. Trejo, J., Hammes, S. R., and Coughlin, S. R. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 13698-13702
16. Trejo, J., Altschuler, Y., Fu, H.-W., Mostov, K. E., and Coughlin, S. R. (2000) J. Biol. Chem. 275, 31255-31265
17. Hammes, S. R., Shapiro, M. J., and Coughlin, S. R. (1999) Biochemistry 38, 2486-2493
18. Hung, D. T., Vu, T. K., Wheaton, V. I., Ishii, K., and Coughlin, S. R. (1992) J. Clin. Investig. 89, 1350-1353
19. Ishii, K., Chen, J., Ishii, M., Koch, W. J., Freedman, N. J., Lefkowitz, R. J., and Coughlin, S. R. (1994) J. Biol. Chem. 269, 1125-1130
20. Kohout, T. A., Lin, F.-T., Perry, S. J., Conner, D. A., and Lefkowitz, R. J. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 1601-1606
21. Offermanns, S., Toombs, C. F., Hu, Y. H., and Simon, M. I. (1997) Nature 389, 183-186
22. Altschuler, Y., Barbas, S. M., Terlecky, L. J., Tang, K., Hardy, S., Mostov, K. E., and Schmid, S. L. (1998) J. Cell Biol. 143, 1871-1881
23. Whistler, J. L., Tsao, P., and von Zastrow, M. (2001) J. Biol. Chem. 276, 34331-34338
24. Bonifacino, J. S., and Traub, L. M. (2003) Annu. Rev. Biochem. 72, 395-447
25. Diviani, D., Lattion, A.-L., Abuin, L., Staub, O., and Cotecchia, S. (2003) J. Biol. Chem. 278, 19331-19340
26. Fan, G.-H., Yang, W., Wang, X.-J., Qian, Q., and Richmond, A. (2001) Biochemistry. 40, 791-800
27. Laporte, S., Oakley, R. H., Zhang, J., Holt, J. A., Ferguson, S. S. G., Caron, M. G., and Barak, L. S. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 3712-3717
28. Kim, Y.-M., and Benovic, J. L. (2002) J. Biol. Chem. 277, 30760-30768