Interfacing picoliter droplet microfluidics with addressable microliter compartments using fluorescence activated cell sorting

Sensors and Actuators, B: Chemical

Volumn 194, Issue , 2014, Pages 249-254

  Bai, Yunpeng ^a   Weibull, Emilie ^a   Joensson, Haakan N ^a   Andersson Svahn, Helene ^a  

^a ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

Agarose beads; Droplet microfluidics; Escherichia coli; Fluorescence activated cell sorting; Microwell slide

Indexed keywords

AGAROSE BEADS; DROPLET MICROFLUIDICS; ESCHERICHIA COLI (E. COLI); FLUORESCENCE ACTIVATED CELL SORTING; FLUORESCENCE-ACTIVATED CELL SORTERS; HIGH-ACCURACY POSITIONING; MICRO WELLS; MICROFLUIDIC PLATFORMS;

CELLS; CYTOLOGY; DROPS; ESCHERICHIA COLI; FLUORESCENCE; GELATION; MICROCHANNELS; SPRAY NOZZLES;

MICROFLUIDICS;

EID: 84892492768     PISSN: 09254005     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.snb.2013.12.089     Document Type: Article

References (53)

1. A.B. Theberge, F. Courtois, Y. Schaerli, M. Fischlechner, C. Abell, and F. Hollfelder et al. Microdroplets in microfluidics: an evolving platform for discoveries in chemistry and biology Angew. Chem. Int. Ed. Engl. 49 2010 5846 5868
2. M.T. Guo, A. Rotem, J.A. Heyman, and D.A. Weitz Droplet microfluidics for high-throughput biological assays Lab Chip 12 2012 2146 2155
3. B. Kintses, L.D. van Vliet, S.R.A. Devenish, and F. Hollfelder Microfluidic droplets: new integrated workflows for biological experiments Curr. Opin. Chem. Biol. 14 2010 548 555
4. J.J. Agresti, E. Antipov, A.R. Abate, K. Ahn, A.C. Rowat, and J.C. Baret et al. Ultrahigh-throughput screening in drop-based microfluidics for directed evolution Proc. Natl. Acad. Sci. U.S.A. 107 2010 4004 4009
5. B. Kintses, C. Hein, M.F. Mohamed, M. Fischlechner, F. Courtois, and C. Leine et al. Picoliter cell lysate assays in microfluidic droplet compartments for directed enzyme evolution Chem. Biol. 19 2012 1001 1009
6. B.M. Paegel, and G.F. Joyce Microfluidic compartmentalized directed evolution Chem. Biol. 17 2010 717 724
7. H.N. Joensson, and H.A. Svahn Droplet microfluidics - a tool for single-cell analysis Angew. Chem. Int. Ed. 51 2012 12176 12192
8. M.Y. He, J.S. Edgar, G.D.M. Jeffries, R.M. Lorenz, J.P. Shelby, and D.T. Chiu Selective encapsulation of single cells and subcellular organelles into picoliter- and femtoliter-volume droplets Anal. Chem. 77 2005 1539 1544
9. J. Clausell-Tormos, D. Lieber, J.C. Baret, A. El-Harrak, O.J. Miller, and L. Frenz et al. Droplet-based microfluidic platforms for the encapsulation and screening of mammalian cells and multicellular organisms Chem. Biol. 15 2008 427 15 (2008) 875
10. F. Pereira, X.Z. Niu, A.J. deMello, and A. Nano LC-MALDI mass spectrometry droplet interface for the analysis of complex protein samples PLoS One 8 2013
11. S.L. Sjostrom, H.N. Joensson, and H.A. Svahn Multiplex analysis of enzyme kinetics and inhibition by droplet microfluidics using picoinjectors Lab Chip 13 2013 1754 1761
12. A. Huebner, L.F. Olguin, D. Bratton, G. Whyte, W.T.S. Huck, and A.J. de Mello et al. Development of quantitative cell-based enzyme assays in microdroplets Anal. Chem. 80 2008 3890 3896
13. A.M. Huebner, C. Abell, W.T.S. Huck, C.N. Baroud, and F. Hollfelder Monitoring a reaction at submillisecond resolution in picoliter volumes Anal. Chem. 83 2011 1462 1468
14. B.J. Hindson, K.D. Ness, D.A. Masquelier, P. Belgrader, N.J. Heredia, and A.J. Makarewicz et al. High-throughput droplet digital pcr system for absolute quantitation of DNA copy number Anal. Chem. 83 2011 8604 8610
15. H. White, A. So, R. Koehler, C. Troup, N. Heredia, and C. Hindson et al. Ultra-sensitive detection of somatic mutations by droplet digital PCR with conventional TaqMan assays J. Med. Genet. 49 2012 S55 S
16. D.J. Eastburn, A. Sciambi, and A.R. Abate Picoinjection enables digital detection of RNA with droplet RT-PCR PLoS One 8 2013
17. M.C. Strain, S.M. Lada, T. Luong, S.E. Rought, S. Gianella, and V.H. Terry et al. Highly precise measurement of HIV DNA by droplet digital PCR PLoS One 8 2013 e55943 10.1371/journal.pone.0055943
18. J. Goodall, V. Spivey, C. Thome, S. Dixon, J. Frampton, and P. Morrill Validation of droplet digital PCR using gDNA, FFPE and xenograft reference standards J. Mol. Diagn. 14 2012 728
19. D. Pekin, Y. Skhiri, J.C. Baret, D. Le Corre, L. Mazutis, and C. Ben Salem et al. Quantitative and sensitive detection of rare mutations using droplet-based microfluidics Lab Chip 11 2011 2156 2166
20. O.J. Miller, A. El Harrak, T. Mangeat, J.C. Baret, L. Frenz, and B. El Debs et al. High-resolution dose-response screening using droplet-based microfluidics Proc. Natl. Acad. Sci. U.S.A. 109 2012 378 383
21. J. Clausell-Tormos, A.D. Griffiths, and C.A. Merten An automated two-phase microfluidic system for kinetic analyses and the screening of compound libraries Lab Chip 10 2010 1302 1307
22. K. Churski, T.S. Kaminski, S. Jakiela, W. Kamysz, W. Baranska-Rybak, and D.B. Weibel et al. Rapid screening of antibiotic toxicity in an automated microdroplet system Lab Chip 12 2012 1629 1637
23. T.T. Fu, Y.N. Wu, Y.G. Ma, and H.Z. Li Droplet formation and breakup dynamics in microfluidic flow-focusing devices: from dripping to jetting Chem. Eng. Sci. 84 2012 207 217
24. M. Seo, C. Paquet, Z.H. Nie, S.Q. Xu, and E. Kumacheva Microfluidic consecutive flow-focusing droplet generators Soft Matter 3 2007 986 992
25. D.R. Link, S.L. Anna, D.A. Weitz, and H.A. Stone Geometrically mediated breakup of drops in microfluidic devices Phys. Rev. Lett. 92 2004
26. L. Mazutis, J.C. Baret, and A.D. Griffiths A fast and efficient microfluidic system for highly selective one-to-one droplet fusion Lab Chip 9 2009 2665 2672
27. L. Mazutis, and A.D. Griffiths Selective droplet coalescence using microfluidic systems Lab Chip 12 2012 1800 1806
28. A.R. Abate, T. Hung, P. Mary, J.J. Agresti, and D.A. Weitz High-throughput injection with microfluidics using picoinjectors Proc. Natl. Acad. Sci. U.S.A. 107 2010 19163 19166
29. B. O'Donovan, D.J. Eastburn, and A.R. Abate Electrode-free picoinjection of microfluidic drops Lab Chip 12 2012 4029 4032
30. K. Ahn, J. Agresti, H. Chong, M. Marquez, and D.A. Weitz Electrocoalescence of drops synchronized by size-dependent flow in microfluidic channels Appl. Phys. Lett. 88 2006
31. C. Priest, S. Herminghaus, and R. Seemann Controlled electrocoalescence in microfluidics: targeting a single lamella Appl. Phys. Lett. 89 2006
32. L. Frenz, K. Blank, E. Brouzes, and A.D. Griffiths Reliable microfluidic on-chip incubation of droplets in delay-lines Lab Chip 9 2009 1344 1348
33. J.U. Shim, L.F. Olguin, G. Whyte, D. Scott, A. Babtie, and C. Abell et al. Simultaneous determination of gene expression and enzymatic activity in individual bacterial cells in microdroplet compartments J. Am. Chem. Soc. 131 2009 15251 15256
34. L. Mazutis, A.F. Araghi, O.J. Miller, J.C. Baret, L. Frenz, and A. Janoshazi et al. Droplet-based microfluidic systems for high-throughput single DNA molecule isothermal amplification and analysis Anal. Chem. 81 2009 4813 4821
35. L. Mazutis, J. Gilbert, W.L. Ung, D.A. Weitz, A.D. Griffiths, and J.A. Heyman Single-cell analysis and sorting using droplet-based microfluidics Nat. Protoc. 8 2013 870 891
36. J.C. Baret, O.J. Miller, V. Taly, M. Ryckelynck, A. El-Harrak, and L. Frenz et al. Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity Lab Chip 9 2009 1850 1858
37. K. Ahn, C. Kerbage, T.P. Hunt, R.M. Westervelt, D.R. Link, and D.A. Weitz Dielectrophoretic manipulation of drops for high-speed microfluidic sorting devices Appl. Phys. Lett. 88 2006
38. R.R. Pompano, W.S. Liu, W.B. Du, and R.F. Ismagilov Microfluidics using spatially defined arrays of droplets in one, two, and three dimensions Annu. Rev. Anal. Chem. 4 2011 59 81
39. B. El Debs, R. Utharala, I.V. Balyasnikova, A.D. Griffiths, and C.A. Merten Functional single-cell hybridoma screening using droplet-based microfluidics Proc. Natl. Acad. Sci. U.S.A. 109 2012 11570 11575
40. Y.P. Bai, X.M. He, D.S. Liu, S.N. Patil, D. Bratton, and A. Huebner et al. A double droplet trap system for studying mass transport across a droplet-droplet interface Lab Chip 10 2010 1281 1285
41. A. Huebner, D. Bratton, G. Whyte, M. Yang, A.J. deMello, and C. Abell et al. Static microdroplet arrays: a microfluidic device for droplet trapping, incubation and release for enzymatic and cell-based assays Lab Chip 9 2009 692 698
42. R. Novak, Y. Zeng, J. Shuga, G. Venugopalan, D.A. Fletcher, and M.T. Smith et al. Single-cell multiplex gene detection and sequencing with microfluidically generated agarose emulsions Angew. Chem. Int. Ed. 50 2011 390 395
43. A. Aharoni, K. Thieme, C.P.C. Chiu, S. Buchini, L.L. Lairson, and H.M. Chen et al. High-throughput screening methodology for the directed evolution of glycosyltransferases Nat. Methods 3 2006 609 614
44. Z. Zhu, W.H. Zhang, X.F. Leng, M.X. Zhang, Z.C. Guan, and J.Q. Lu et al. Highly sensitive and quantitative detection of rare pathogens through agarose droplet microfluidic emulsion PCR at the single-cell level Lab Chip 12 2012 3907 3913
45. H.F. Zhang, G. Jenkins, Y. Zou, Z. Zhu, and C.J. Yang Massively parallel single-molecule and single-cell emulsion reverse transcription polymerase chain reaction using agarose droplet microfluidics Anal. Chem. 84 2012 3599 3606
46. L. Yan, Z. Zhu, Y. Zou, Y.S. Huang, D.W. Liu, and S.S. Jia et al. Target-responsive sweet hydrogel with glucometer readout for portable and quantitative detection of non-glucose targets J. Am. Chem. Soc. 135 2013 3748 3751
47. M.S. Fitzsimons, M. Novotny, C.C. Lo, A.E.K. Dichosa, J.L. Yee-Greenbaum, and J.P. Snook et al. Nearly finished genomes produced using gel microdroplet culturing reveal substantial intraspecies genomic diversity within the human microbiome Genome Res. 23 2013 878 888
48. Y.J. Eun, A.S. Utada, M.F. Copeland, S. Takeuchi, and D.B. Weibel Encapsulating bacteria in agarose microparticles using microfluidics for high-throughput cell analysis and isolation ACS Chem. Biol. 6 2011 260 266
49. S. Lindstrom, R. Larsson, and H.A. Svahn Towards high-throughput single cell/clone cultivation and analysis Electrophoresis 29 2008 1219 1227
50. S. Lindstrom, M. Hammond, H. Brismar, H. Andersson-Svahn, and A. Ahmadian PCR amplification and genetic analysis in a microwell cell culturing chip Lab Chip 9 2009 3465 3471
51. Y. Xia, J.A. Rogers, K.E. Paul, and G.M. Whitesides Unconventional methods for fabricating and patterning nanostructures Chem. Rev. 99 1999 1823 1848
52. A.E. Carnes, C.P. Hodgson, and J.A. Williams Inducible Escherichia coli fermentation for increased plasmid DNA production Biotechnol. Appl. Biochem. 45 2006 155 166
53. S.L. Sjostrom, Y. Bai, M. Huang, J. Nielsen, H.N. Joensson, and H. Andersson-Svahn Droplet based directed evolution of yeast cell factories doubles production of industrial enzymes 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences Freiburg, Germany 2013 1270 1272