-
1
-
-
84862212456
-
Droplet microfluidics for high-throughput biological assays
-
Guo, M.T., Rotem, A., Heyman, J.A. & Weitz, D.A. Droplet microfluidics for high-throughput biological assays. Lab Chip 12, 2146-2155 (2012
-
(2012)
Lab Chip
, vol.12
, pp. 2146-2155
-
-
Guo, M.T.1
Rotem, A.2
Heyman, J.A.3
Weitz, D.A.4
-
2
-
-
77957755250
-
Microfluidic droplets: New integrated workflows for biological experiments
-
Kintses, B., van Vliet, L.D., Devenish, S.R. & Hollfelder, F. Microfluidic droplets: New integrated workflows for biological experiments. Curr. Opin. Chem. Biol. 14, 548-555 (2010
-
(2010)
Curr. Opin. Chem. Biol
, vol.14
, pp. 548-555
-
-
Kintses, B.1
Van Vliet, L.D.2
Devenish, S.R.3
Hollfelder, F.4
-
3
-
-
77955563148
-
Microdroplets in microfluidics: An evolving platform for discoveries in chemistry and biology
-
Theberge, A.B. et al. Microdroplets in microfluidics: An evolving platform for discoveries in chemistry and biology. Angew. Chem. Int. Ed. 49, 5846-5868 (2010
-
(2010)
Angew. Chem. Int. Ed.
, vol.49
, pp. 5846-5868
-
-
Theberge, A.B.1
-
4
-
-
0032832775
-
Drug screening-beyond the bottleneck
-
Dove, A. Drug screening-beyond the bottleneck. Nat. Biotechnol. 17, 859-863 (1999
-
(1999)
Nat. Biotechnol
, vol.17
, pp. 859-863
-
-
Dove, A.1
-
5
-
-
1642351216
-
Geometrically mediated breakup of drops in microfluidic devices
-
Link, D.R., Anna, S.L., Weitz, D.A. & Stone, H.A. Geometrically mediated breakup of drops in microfluidic devices. Phys. Rev. Lett. 92, 054503 (2004
-
(2004)
Phys. Rev. Lett
, vol.92
, pp. 054503
-
-
Link, D.R.1
Anna, S.L.2
Weitz, D.A.3
Stone, H.A.4
-
6
-
-
69549097381
-
A fast and efficient microfluidic system for highly selective one-to-one droplet fusion
-
Mazutis, L., Baret, J.C. & Griffiths, A.D. A fast and efficient microfluidic system for highly selective one-to-one droplet fusion. Lab Chip 9, 2665-2672 (2009
-
(2009)
Lab Chip
, vol.9
, pp. 2665-2672
-
-
Mazutis, L.1
Baret, J.C.2
Griffiths, A.D.3
-
7
-
-
84860353468
-
Selective droplet coalescence using microfluidic systems
-
Mazutis, L. & Griffiths, A.D. Selective droplet coalescence using microfluidic systems. Lab Chip 12, 1800-1806 (2012
-
(2012)
Lab Chip
, vol.12
, pp. 1800-1806
-
-
Mazutis, L.1
Griffiths, A.D.2
-
8
-
-
33745613020
-
Electrocoalescence of drops synchronized by size-dependent flow in microfluidic channels
-
Ahn, K., Agresti, J., Chong, H., Marquez, M. & Weitz, D.A. Electrocoalescence of drops synchronized by size-dependent flow in microfluidic channels. Appl. Phys. Lett. 88, 264105-264103 (2006
-
(2006)
Appl. Phys. Lett
, vol.88
, pp. 264105-264103
-
-
Ahn, K.1
Agresti, J.2
Chong, H.3
Marquez, M.4
Weitz, D.A.5
-
9
-
-
27244443193
-
Droplet fusion by alternating current (AC) field electrocoalescence in microchannels
-
Chabert, M., Dorfman, K.D. & Viovy, J.L. Droplet fusion by alternating current (AC) field electrocoalescence in microchannels. Electrophoresis 26, 3706-3715 (2005
-
(2005)
Electrophoresis
, vol.26
, pp. 3706-3715
-
-
Chabert, M.1
Dorfman, K.D.2
Viovy, J.L.3
-
10
-
-
33749239595
-
Controlled electrocoalescence in microfluidics: Targeting a single lamella
-
Priest, C., Herminghaus, S. & Seemann, R. Controlled electrocoalescence in microfluidics: Targeting a single lamella. Appl. Phys. Lett. 89, 134101 (2006
-
(2006)
Appl. Phys. Lett
, vol.89
, pp. 134101
-
-
Priest, C.1
Herminghaus, S.2
Seemann, R.3
-
11
-
-
78650594173
-
High-throughput injection with microfluidics using picoinjectors
-
Abate, A.R., Hung, T., Mary, P., Agresti, J.J. & Weitz, D.A. High-throughput injection with microfluidics using picoinjectors. Proc. Natl. Acad. Sci. USA 107, 19163-19166 (2010
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 19163-19166
-
-
Abate, A.R.1
Hung, T.2
Mary, P.3
Agresti, J.J.4
Weitz, D.A.5
-
12
-
-
33845864473
-
Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins
-
Li, L. et al. Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins. Proc. Natl. Acad. Sci. USA 103, 19243-19248 (2006
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 19243-19248
-
-
Li, L.1
-
13
-
-
54349106182
-
Pillar-induced droplet merging in microfluidic circuits
-
Niu, X., Gulati, S., Edel, J.B. & deMello, A.J. Pillar-induced droplet merging in microfluidic circuits. Lab Chip 8, 1837-1841 (2008
-
(2008)
Lab Chip
, vol.8
, pp. 1837-1841
-
-
Niu, X.1
Gulati, S.2
Edel, J.B.3
DeMello, A.J.4
-
14
-
-
65649102240
-
Reliable microfluidic on-chip incubation of droplets in delay-lines
-
Frenz, L., Blank, K., Brouzes, E. & Griffiths, A.D. Reliable microfluidic on-chip incubation of droplets in delay-lines. Lab Chip 9, 1344-1348 (2009
-
(2009)
Lab Chip
, vol.9
, pp. 1344-1348
-
-
Frenz, L.1
Blank, K.2
Brouzes, E.3
Griffiths, A.D.4
-
15
-
-
80054988291
-
1-Million droplet array with wide-field fluorescence imaging for digital PCR
-
Hatch, A.C. et al. 1-Million droplet array with wide-field fluorescence imaging for digital PCR. Lab Chip 11, 3838-3845 (2011
-
(2011)
Lab Chip
, vol.11
, pp. 3838-3845
-
-
Hatch, A.C.1
-
16
-
-
70350331103
-
Simultaneous determination of gene expression and enzymatic activity in individual bacterial cells in microdroplet compartments
-
Shim, J.U. et al. Simultaneous determination of gene expression and enzymatic activity in individual bacterial cells in microdroplet compartments. J. Am. Chem. Soc. 42, 15251-15256 (2009
-
(2009)
J. Am. Chem. Soc
, vol.42
, pp. 15251-15256
-
-
Shim, J.U.1
-
17
-
-
67249135232
-
Droplet-based microfluidic systems for high-throughput single DNA molecule isothermal amplification and analysis
-
Mazutis, L. et al. Droplet-based microfluidic systems for high-throughput single DNA molecule isothermal amplification and analysis. Anal. Chem. 81, 4813-4821 (2009
-
(2009)
Anal. Chem
, vol.81
, pp. 4813-4821
-
-
Mazutis, L.1
-
19
-
-
84856748588
-
Teaching single-cell digital analysis using droplet-based microfluidics
-
Najah, M., Griffiths, A.D. & Ryckelynck, M. Teaching single-cell digital analysis using droplet-based microfluidics. Anal. Chem. 84, 1202-1209 (2012
-
(2012)
Anal. Chem
, vol.84
, pp. 1202-1209
-
-
Najah, M.1
Griffiths, A.D.2
Ryckelynck, M.3
-
20
-
-
30744474931
-
Dielectrophoretic manipulation of drops for high-speed microfluidic sorting devices
-
Ahn, K. et al. Dielectrophoretic manipulation of drops for high-speed microfluidic sorting devices. Appl. Phys. Lett. 88, 024104 (2006
-
(2006)
Appl. Phys. Lett
, vol.88
, pp. 024104
-
-
Ahn, K.1
-
21
-
-
69549119766
-
Surface acoustic wave (SAW) directed droplet flow in microfluidics for PDMS devices
-
Franke, T., Abate, A.R., Weitz, D.A. & Wixforth, A. Surface acoustic wave (SAW) directed droplet flow in microfluidics for PDMS devices. Lab Chip 9, 2625-2627 (2009
-
(2009)
Lab Chip
, vol.9
, pp. 2625-2627
-
-
Franke, T.1
Abate, A.R.2
Weitz, D.A.3
Wixforth, A.4
-
22
-
-
84863977787
-
Functional single-cell hybridoma screening using droplet-based microfluidics
-
Debs, B.E., Utharala, R., Balyasnikova, I.V., Griffiths, A.D. & Merten, C.A. Functional single-cell hybridoma screening using droplet-based microfluidics. Proc. Natl. Acad. Sci. USA 109, 11570-11575 (2012
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 11570-11575
-
-
Debs, B.E.1
Utharala, R.2
Balyasnikova, I.V.3
Griffiths, A.D.4
Merten, C.A.5
-
23
-
-
77949552684
-
High-throughput screening of enzymes by retroviral display using droplet-based microfluidics
-
Granieri, L., Baret, J.C., Griffiths, A.D. & Merten, C.A. High-throughput screening of enzymes by retroviral display using droplet-based microfluidics. Chem. Biol. 17, 229-235 (2010
-
(2010)
Chem. Biol
, vol.17
, pp. 229-235
-
-
Granieri, L.1
Baret, J.C.2
Griffiths, A.D.3
Merten, C.A.4
-
24
-
-
15444376608
-
Selective encapsulation of single cells and subcellular organelles into picoliter- and femtoliter-volume droplets
-
He, M. et al. Selective encapsulation of single cells and subcellular organelles into picoliter- and femtoliter-volume droplets. Anal. Chem. 77, 1539-1544 (2005
-
(2005)
Anal. Chem
, vol.77
, pp. 1539-1544
-
-
He, M.1
-
25
-
-
43149111583
-
Droplet-based microfluidic platforms for the encapsulation and screening of mammalian cells and multicellular organisms
-
Clausell-Tormos, J. et al. Droplet-based microfluidic platforms for the encapsulation and screening of mammalian cells and multicellular organisms. Chem. Biol. 15, 427-437 (2008
-
(2008)
Chem. Biol
, vol.15
, pp. 427-437
-
-
Clausell-Tormos, J.1
-
26
-
-
46149091744
-
Drop-based microfluidic devices for encapsulation of single cells
-
Koster, S. et al. Drop-based microfluidic devices for encapsulation of single cells. Lab Chip 8, 1110-1115 (2008
-
(2008)
Lab Chip
, vol.8
, pp. 1110-1115
-
-
Koster, S.1
-
27
-
-
70149096883
-
Droplet microfluidic technology for single-cell high-throughput screening
-
Brouzes, E. et al. Droplet microfluidic technology for single-cell high-throughput screening. Proc. Natl. Acad. Sci. USA 106, 14195-14200 (2009
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 14195-14200
-
-
Brouzes, E.1
-
28
-
-
69549121922
-
Isolation incubation, and parallel functional testing and identification by FISH of rare microbial single-copy cells from multi-species mixtures using the combination of chemistrode and stochastic confinement
-
Liu, W., Kim, H.J., Lucchetta, E.M., Du, W. & Ismagilov, R.F. Isolation, incubation, and parallel functional testing and identification by FISH of rare microbial single-copy cells from multi-species mixtures using the combination of chemistrode and stochastic confinement. Lab Chip 9, 2153-2162 (2009
-
(2009)
Lab Chip
, vol.9
, pp. 2153-2162
-
-
Liu, W.1
Kim, H.J.2
Lucchetta, E.M.3
Du, W.4
Ismagilov, R.F.5
-
29
-
-
66149131750
-
An integrated cell culture lab on a chip: Modular microdevices for cultivation of mammalian cells and delivery into microfluidic microdroplets
-
Hufnagel, H. et al. An integrated cell culture lab on a chip: Modular microdevices for cultivation of mammalian cells and delivery into microfluidic microdroplets. Lab Chip 9, 1576-1582 (2009
-
(2009)
Lab Chip
, vol.9
, pp. 1576-1582
-
-
Hufnagel, H.1
-
30
-
-
77951080101
-
High-performance single cell genetic analysis using microfluidic emulsion generator arrays
-
Zeng, Y., Novak, R., Shuga, J., Smith, M.T. & Mathies, R.A. High-performance single cell genetic analysis using microfluidic emulsion generator arrays. Anal. Chem. 82, 3183-3190 (2010
-
(2010)
Anal. Chem
, vol.82
, pp. 3183-3190
-
-
Zeng, Y.1
Novak, R.2
Shuga, J.3
Smith, M.T.4
Mathies, R.A.5
-
31
-
-
84865213657
-
Droplet microfluidics for amplification-free genetic detection of single cells
-
Rane, T.D., Zec, H.C., Puleo, C., Lee, A.P. & Wang, T.H. Droplet microfluidics for amplification-free genetic detection of single cells. Lab Chip 12, 3341-3347 (2012
-
(2012)
Lab Chip
, vol.12
, pp. 3341-3347
-
-
Rane, T.D.1
Zec, H.C.2
Puleo, C.3
Lee, A.P.4
Wang, T.H.5
-
32
-
-
43949083044
-
Development of quantitative cell-based enzyme assays in microdroplets
-
Huebner, A. et al. Development of quantitative cell-based enzyme assays in microdroplets. Anal. Chem. 80, 3890-3896 (2008
-
(2008)
Anal. Chem
, vol.80
, pp. 3890-3896
-
-
Huebner, A.1
-
33
-
-
77954190372
-
Quantitative cell-based reporter gene assays using droplet-based microfluidics
-
Baret, J.C., Beck, Y., Billas-Massobrio, I., Moras, D. & Griffiths, A.D. Quantitative cell-based reporter gene assays using droplet-based microfluidics. Chem. Biol. 17, 528-536 (2010
-
(2010)
Chem. Biol
, vol.17
, pp. 528-536
-
-
Baret, J.C.1
Beck, Y.2
Billas-Massobrio, I.3
Moras, D.4
Griffiths, A.D.5
-
34
-
-
33947184356
-
Quantitative detection of protein expression in single cells using droplet microfluidics
-
Huebner, A. et al. Quantitative detection of protein expression in single cells using droplet microfluidics. Chem. Commun. (Camb) 28, 1218-1220 (2007
-
(2007)
Chem. Commun. (Camb)
, vol.28
, pp. 1218-1220
-
-
Huebner, A.1
-
35
-
-
55949131242
-
The chemistrode: A droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution
-
Chen, D. et al. The chemistrode: A droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution. Proc. Natl. Acad. Sci. USA 105, 16843-16848 (2008
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 16843-16848
-
-
Chen, D.1
-
36
-
-
79957476318
-
A microdroplet dilutor for high-throughput screening
-
Niu, X., Gielen, F., Edel, J.B. & deMello, A.J. A microdroplet dilutor for high-throughput screening. Nat. Chem. 3, 437-442 (2011
-
(2011)
Nat. Chem
, vol.3
, pp. 437-442
-
-
Niu, X.1
Gielen, F.2
Edel, J.B.3
De Mello, A.J.4
-
37
-
-
70349682763
-
Multi-step microfluidic droplet processing: Kinetic analysis of an in vitro-translated enzyme
-
Mazutis, L. et al. Multi-step microfluidic droplet processing: Kinetic analysis of an in vitro-translated enzyme. Lab Chip 9, 2902-2908 (2009
-
(2009)
Lab Chip
, vol.9
, pp. 2902-2908
-
-
Mazutis, L.1
-
38
-
-
79958842027
-
Quantitative and sensitive detection of rare mutations using droplet-based microfluidics
-
Pekin, D. et al. Quantitative and sensitive detection of rare mutations using droplet-based microfluidics. Lab Chip 11, 2156-2166 (2011
-
(2011)
Lab Chip
, vol.11
, pp. 2156-2166
-
-
Pekin, D.1
-
39
-
-
79958787922
-
Multiplex digital PCR: Breaking the one target per color barrier of quantitative PCR
-
Zhong, Q. et al. Multiplex digital PCR: Breaking the one target per color barrier of quantitative PCR. Lab Chip 11, 2167-2174 (2011
-
(2011)
Lab Chip
, vol.11
, pp. 2167-2174
-
-
Zhong, Q.1
-
40
-
-
81255175501
-
High-throughput droplet digital PCR system for absolute quantitation of DNA copy number
-
Hindson, B.J. et al. High-throughput droplet digital PCR system for absolute quantitation of DNA copy number. Anal. Chem. 83, 8604-8610 (2011
-
(2011)
Anal. Chem
, vol.83
, pp. 8604-8610
-
-
Hindson, B.J.1
-
41
-
-
70449339945
-
Microdroplet-based PCR enrichment for large-scale targeted sequencing
-
Tewhey, R. et al. Microdroplet-based PCR enrichment for large-scale targeted sequencing. Nat. Biotechnol. 27, 1025-1031 (2009
-
(2009)
Nat. Biotechnol
, vol.27
, pp. 1025-1031
-
-
Tewhey, R.1
-
42
-
-
84856010916
-
High-resolution dose-response screening using droplet-based microfluidics
-
Miller, O.J. et al. High-resolution dose-response screening using droplet-based microfluidics. Proc. Natl. Acad. Sci. USA 109, 378-383 (2012
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 378-383
-
-
Miller, O.J.1
-
43
-
-
77951899852
-
An automated two-phase microfluidic system for kinetic analyses and the screening of compound libraries
-
Clausell-Tormos, J., Griffiths, A.D. & Merten, C.A. An automated two-phase microfluidic system for kinetic analyses and the screening of compound libraries. Lab Chip 10, 1302-1307 (2010
-
(2010)
Lab Chip
, vol.10
, pp. 1302-1307
-
-
Clausell-Tormos, J.1
Griffiths, A.D.2
Merten, C.A.3
-
44
-
-
84859799161
-
Rapid screening of antibiotic toxicity in an automated microdroplet system
-
Churski, K. et al. Rapid screening of antibiotic toxicity in an automated microdroplet system. Lab Chip 12, 1629-1637 (2012
-
(2012)
Lab Chip
, vol.12
, pp. 1629-1637
-
-
Churski, K.1
-
45
-
-
77749270677
-
Ultrahigh-throughput screening in drop-based microfluidics for directed evolution
-
Agresti, J.J. et al. Ultrahigh-throughput screening in drop-based microfluidics for directed evolution. Proc. Natl. Acad. Sci. USA 107, 4004-4009 (2010
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 4004-4009
-
-
Agresti, J.J.1
-
46
-
-
84865492433
-
Picoliter cell lysate assays in microfluidic droplet compartments for directed enzyme evolution
-
Kintses, B. et al. Picoliter cell lysate assays in microfluidic droplet compartments for directed enzyme evolution. Chem. Biol. 19, 1001-1009
-
Chem. Biol
, vol.19
, pp. 1001-1009
-
-
Kintses, B.1
-
47
-
-
77955457208
-
Microfluidic compartmentalized directed evolution
-
Paegel, B.M. & Joyce, G.F. Microfluidic compartmentalized directed evolution. Chem. Biol. 17, 717-724 (2010
-
(2010)
Chem. Biol
, vol.17
, pp. 717-724
-
-
Paegel, B.M.1
Joyce, G.F.2
-
48
-
-
0036882588
-
Perfluorochemical respiratory gas carriers: Benefits to cell culture systems
-
Lowe, K.C. Perfluorochemical respiratory gas carriers: Benefits to cell culture systems. J. Fluorine Chem. 118, 19-26 (2002
-
(2002)
J. Fluorine Chem
, vol.118
, pp. 19-26
-
-
Lowe, K.C.1
-
49
-
-
0000992534
-
The solubility of fluorocarbons
-
Scott, R.L. The solubility of fluorocarbons. J. Am. Chem. Soc. 70, 4090-4093 (1948
-
(1948)
J. Am. Chem. Soc
, vol.70
, pp. 4090-4093
-
-
Scott, R.L.1
-
50
-
-
33947455774
-
The solubility of organic solids in fluorocarbon derivatives
-
Simons, J.H. & Linevsky, M.J. The solubility of organic solids in fluorocarbon derivatives. J. Am. Chem. Soc. 74, 4750-4751 (1952
-
(1952)
J. Am. Chem. Soc
, vol.74
, pp. 4750-4751
-
-
Simons, J.H.1
Linevsky, M.J.2
-
51
-
-
0031854986
-
Man-made cell-like compartments for molecular evolution
-
Tawfik, D.S. & Griffiths, A.D. Man-made cell-like compartments for molecular evolution. Nat. Biotechnol. 16, 652-656 (1998
-
(1998)
Nat. Biotechnol
, vol.16
, pp. 652-656
-
-
Tawfik, D.S.1
Griffiths, A.D.2
-
52
-
-
67649973848
-
Fluorescence-activated droplet sorting (FADS): Efficient microfluidic cell sorting based on enzymatic activity
-
Baret, J.C. et al. Fluorescence-activated droplet sorting (FADS): Efficient microfluidic cell sorting based on enzymatic activity. Lab Chip 9, 1850-1858 (2009
-
(2009)
Lab Chip
, vol.9
, pp. 1850-1858
-
-
Baret, J.C.1
-
53
-
-
79959926783
-
Intracellular protein determination using droplet-based immunoassays
-
Martino, C. et al. Intracellular protein determination using droplet-based immunoassays. Anal. Chem. 83, 5361-5368 (2011
-
(2011)
Anal. Chem
, vol.83
, pp. 5361-5368
-
-
Martino, C.1
-
54
-
-
41449096970
-
On-chip single-copy real-time reverse-transcription PCR in isolated picoliter droplets
-
Beer, N.R. et al. On-chip single-copy real-time reverse-transcription PCR in isolated picoliter droplets. Anal. Chem. 80, 1854-1858 (2008
-
(2008)
Anal. Chem
, vol.80
, pp. 1854-1858
-
-
Beer, N.R.1
-
55
-
-
58149478136
-
Continuous-flow polymerase chain reaction of single-copy DNA in microfluidic microdroplets
-
Schaerli, Y. et al. Continuous-flow polymerase chain reaction of single-copy DNA in microfluidic microdroplets. Anal. Chem. 81, 302-306 (2009
-
(2009)
Anal. Chem
, vol.81
, pp. 302-306
-
-
Schaerli, Y.1
-
56
-
-
36448957253
-
On-chip, real-time, single-copy polymerase chain reaction in picoliter droplets
-
Beer, N.R. et al. On-chip, real-time, single-copy polymerase chain reaction in picoliter droplets. Anal. Chem. 79, 8471-8475 (2007
-
(2007)
Anal. Chem
, vol.79
, pp. 8471-8475
-
-
Beer, N.R.1
-
57
-
-
0033772183
-
Function-based isolation of novel enzymes from a large library
-
Olsen, M.J. et al. Function-based isolation of novel enzymes from a large library. Nat. Biotechnol. 18, 1071-1074 (2000
-
(2000)
Nat. Biotechnol
, vol.18
, pp. 1071-1074
-
-
Olsen, M.J.1
-
58
-
-
33746439461
-
High-throughput screening methodology for the directed evolution of glycosyltransferases
-
Aharoni, A. et al. High-throughput screening methodology for the directed evolution of glycosyltransferases. Nat. Methods 3, 609-614 (2006
-
(2006)
Nat. Methods
, vol.3
, pp. 609-614
-
-
Aharoni, A.1
-
59
-
-
0034615958
-
Monolithic microfabricated valves and pumps by multilayer soft lithography
-
Unger, M.A., Chou, H.P., Thorsen, T., Scherer, A. & Quake, S.R. Monolithic microfabricated valves and pumps by multilayer soft lithography. Science 288, 113-116 (2000
-
(2000)
Science
, vol.288
, pp. 113-116
-
-
Unger, M.A.1
Chou, H.P.2
Thorsen, T.3
Scherer, A.4
Quake, S.R.5
-
60
-
-
65649122270
-
High-throughput sequencing of the zebrafish antibody repertoire
-
Weinstein, J.A., Jiang, N., White, R.A. III, Fisher, D.S. & Quake, S.R. High-throughput sequencing of the zebrafish antibody repertoire. Science 324, 807-810 (2009
-
(2009)
Science
, vol.324
, pp. 807-810
-
-
Weinstein, J.A.1
Jiang, N.2
White III, R.A.3
Fisher, D.S.4
Quake, S.R.5
-
61
-
-
78651304279
-
Whole-genome molecular haplotyping of single cells
-
Fan, H.C., Wang, J., Potanina, A. & Quake, S.R. Whole-genome molecular haplotyping of single cells. Nat. Biotechnol. 29, 51-57 (2011
-
(2011)
Nat. Biotechnol
, vol.29
, pp. 51-57
-
-
Fan, H.C.1
Wang, J.2
Potanina, A.3
Quake, S.R.4
-
62
-
-
79959830458
-
High-throughput analysis of single hematopoietic stem cell proliferation in microfluidic cell culture arrays
-
Lecault, V. et al. High-throughput analysis of single hematopoietic stem cell proliferation in microfluidic cell culture arrays. Nat. Methods 8, 581-586 (2011
-
(2011)
Nat. Methods
, vol.8
, pp. 581-586
-
-
Lecault, V.1
-
63
-
-
33745072443
-
A microengraving method for rapid selection of single cells producing antigen-specific antibodies
-
Love, J.C., Ronan, J.L., Grotenbreg, G.M., van der Veen, A.G. & Ploegh, H.L. A microengraving method for rapid selection of single cells producing antigen-specific antibodies. Nat. Biotechnol. 24, 703-707 (2006
-
(2006)
Nat. Biotechnol
, vol.24
, pp. 703-707
-
-
Love, J.C.1
Ronan, J.L.2
Grotenbreg, G.M.3
Van Der Veen, A.G.4
Ploegh, H.L.5
-
64
-
-
84863110761
-
Detecting biomarkers with microdroplet technology
-
Taly, V., Pekin, D., El Abed, A. & Laurent-Puig, P. Detecting biomarkers with microdroplet technology. Trends Mol. Med. 18, 405-416 (2012
-
(2012)
Trends Mol. Med
, vol.18
, pp. 405-416
-
-
Taly, V.1
Pekin, D.2
El Abed, A.3
Laurent-Puig, P.4
-
65
-
-
84859887632
-
High-throughput analysis of protein-protein interactions in picoliter-volume droplets using fluorescence polarization
-
Choi, J.W., Kang, D.K., Park, H., deMello, A.J. & Chang, S.I. High-throughput analysis of protein-protein interactions in picoliter-volume droplets using fluorescence polarization. Anal. Chem. 84, 3849-3854 (2012
-
(2012)
Anal. Chem
, vol.84
, pp. 3849-3854
-
-
Choi, J.W.1
Kang, D.K.2
Park, H.3
De Mello, A.J.4
Chang, S.I.5
-
66
-
-
84863075291
-
A homogeneous assay for protein analysis in droplets by fluorescence polarization
-
Joensson, H.N., Zhang, C., Uhlen, M. & Andersson-Svahn, H. A homogeneous assay for protein analysis in droplets by fluorescence polarization. Electrophoresis 33, 436-439 (2012
-
(2012)
Electrophoresis
, vol.33
, pp. 436-439
-
-
Joensson, H.N.1
Zhang, C.2
Uhlen, M.3
Andersson-Svahn, H.4
-
67
-
-
51949096580
-
Monitoring of real-time streptavidin-biotin binding kinetics using droplet microfluidics
-
Srisa-Art, M., Dyson, E.C., Demello, A.J. & Edel, J.B. Monitoring of real-time streptavidin-biotin binding kinetics using droplet microfluidics. Anal. Chem. 80, 7063-7067 (2008
-
(2008)
Anal. Chem
, vol.80
, pp. 7063-7067
-
-
Srisa-Art, M.1
Dyson, E.C.2
Demello, A.J.3
Edel, J.B.4
-
68
-
-
79954554233
-
Ultrafast surface enhanced resonance Raman scattering detection in droplet-based microfluidic systems
-
Cecchini, M.P. et al. Ultrafast surface enhanced resonance Raman scattering detection in droplet-based microfluidic systems. Anal. Chem. 83, 3076-3081 (2011
-
(2011)
Anal. Chem
, vol.83
, pp. 3076-3081
-
-
Cecchini, M.P.1
-
69
-
-
57549110825
-
Enzyme assays
-
Reymond, J.L., Fluxa, V.S. & Maillard, N. Enzyme assays. Chem. Commun. 2009, 34-46 (2009
-
(2009)
Chem. Commun
, vol.2009
, pp. 34-46
-
-
Reymond, J.L.1
Fluxa, V.S.2
Maillard, N.3
-
70
-
-
70349782198
-
Detection and analysis of low-abundance cell-surface biomarkers using enzymatic amplification in microfluidic droplets
-
Joensson, H.N. et al. Detection and analysis of low-abundance cell-surface biomarkers using enzymatic amplification in microfluidic droplets. Angew. Chem. Int. Ed. Engl. 48, 2518-2521 (2009
-
(2009)
Angew. Chem. Int. Ed. Engl
, vol.48
, pp. 2518-2521
-
-
Joensson, H.N.1
-
72
-
-
0037455351
-
Formation Of Dispersions Using "flow focusing" in microchannels
-
Anna, S.L., Bontoux, N. & Stone, H.A. Formation of dispersions using "flow focusing" in microchannels. Appl. Phys. Lett. 82, 364-366 (2003
-
(2003)
Appl. Phys. Lett
, vol.82
, pp. 364-366
-
-
Anna, S.L.1
Bontoux, N.2
Stone, H.A.3
-
73
-
-
33644648479
-
Formation of droplets and bubbles in a microfluidic T-junction - Scaling and mechanism of break-up
-
Garstecki, P., Fuerstman, M.J., Stone, H.A. & Whitesides, G.M. Formation of droplets and bubbles in a microfluidic T-junction - scaling and mechanism of break-up. Lab Chip 6, 437-446 (2006
-
(2006)
Lab Chip
, vol.6
, pp. 437-446
-
-
Garstecki, P.1
Fuerstman, M.J.2
Stone, H.A.3
Whitesides, G.M.4
-
74
-
-
69449101987
-
Impact of inlet channel geometry on microfluidic drop formation
-
Abate, A.R. et al. Impact of inlet channel geometry on microfluidic drop formation. Phys. Rev. E 80, 026310 (2009
-
(2009)
Phys. Rev
, vol.E 80
, pp. 026310
-
-
Abate, A.R.1
-
75
-
-
0035807144
-
Interfacial tension driven monodispersed droplet formation from microfabricated channel array
-
Sugiura, S., Nakajima, M., Iwamoto, S. & Seki, M. Interfacial tension driven monodispersed droplet formation from microfabricated channel array. Langmuir 17, 5562-5566 (2001
-
(2001)
Langmuir
, vol.17
, pp. 5562-5566
-
-
Sugiura, S.1
Nakajima, M.2
Iwamoto, S.3
Seki, M.4
-
76
-
-
84855675958
-
Surfactants in droplet-based microfluidics
-
Baret, J.C. Surfactants in droplet-based microfluidics. Lab Chip 12, 422-433 (2012
-
(2012)
Lab Chip
, vol.12
, pp. 422-433
-
-
Baret, J.C.1
-
77
-
-
66749124156
-
Kinetic aspects of emulsion stabilization by surfactants: A microfluidic analysis
-
Baret, J.C., Kleinschmidt, F., El Harrak, A. & Griffiths, A.D. Kinetic aspects of emulsion stabilization by surfactants: A microfluidic analysis. Langmuir 25, 6088-6093 (2009
-
(2009)
Langmuir
, vol.25
, pp. 6088-6093
-
-
Baret, J.C.1
Kleinschmidt, F.2
El Harrak, A.3
Griffiths, A.D.4
-
78
-
-
13244289982
-
Controlling nonspecific protein adsorption in a plug-based microfluidic system by controlling interfacial chemistry using fluorous-phase surfactants
-
Roach, L.S., Song, H. & Ismagilov, R.F. Controlling nonspecific protein adsorption in a plug-based microfluidic system by controlling interfacial chemistry using fluorous-phase surfactants. Anal. Chem. 77, 785-796 (2005
-
(2005)
Anal. Chem
, vol.77
, pp. 785-796
-
-
Roach, L.S.1
Song, H.2
Ismagilov, R.F.3
-
79
-
-
52649177297
-
Biocompatible surfactants for water-in-fluorocarbon emulsions
-
Holtze, C. et al. Biocompatible surfactants for water-in-fluorocarbon emulsions. Lab Chip 8, 1632-1639 (2008
-
(2008)
Lab Chip
, vol.8
, pp. 1632-1639
-
-
Holtze, C.1
-
80
-
-
81255151150
-
Chemical transfection of cells in picoliter aqueous droplets in fluorocarbon oil
-
Chen, F. et al. Chemical transfection of cells in picoliter aqueous droplets in fluorocarbon oil. Anal. Chem. 83, 8816-8820 (2011
-
(2011)
Anal. Chem
, vol.83
, pp. 8816-8820
-
-
Chen, F.1
-
82
-
-
84867362611
-
Dynamics of molecular transport by surfactants in emulsions
-
Skhiri, Y. Dynamics of molecular transport by surfactants in emulsions. Soft Matter 8, 10618-10627 (2012
-
(2012)
Soft Matter
, vol.8
, pp. 10618-10627
-
-
Skhiri, Y.1
-
83
-
-
79954480112
-
New generation of amino coumarin methyl sulfonate-based fluorogenic substrates for amidase assays in droplet-based microfluidic applications
-
Woronoff, G. et al. New generation of amino coumarin methyl sulfonate-based fluorogenic substrates for amidase assays in droplet-based microfluidic applications. Anal. Chem. 83, 2852-2857 (2011
-
(2011)
Anal. Chem
, vol.83
, pp. 2852-2857
-
-
Woronoff, G.1
-
84
-
-
65249121358
-
Controlling the retention of small molecules in emulsion microdroplets for use in cell-based assays
-
Courtois, F. et al. Controlling the retention of small molecules in emulsion microdroplets for use in cell-based assays. Anal. Chem. 81, 3008-3016 (2009
-
(2009)
Anal. Chem
, vol.81
, pp. 3008-3016
-
-
Courtois, F.1
-
85
-
-
33750453744
-
Cofabrication of electromagnets and microfluidic systems in poly(dimethylsiloxane)
-
Siegel, A.C. et al. Cofabrication of electromagnets and microfluidic systems in poly(dimethylsiloxane). Angew Chem. Int. Ed. Engl. 45, 6877-6882 (2006
-
(2006)
Angew Chem. Int. Ed. Engl
, vol.45
, pp. 6877-6882
-
-
Siegel, A.C.1
-
86
-
-
0032682397
-
The inertial lift on a spherical particle in a plane Poiseuille flow at large channel Reynolds number
-
Asmolov, E.S. The inertial lift on a spherical particle in a plane Poiseuille flow at large channel Reynolds number. J. Fluid Mech. 381, 63-87 (1999
-
(1999)
J. Fluid Mech
, vol.381
, pp. 63-87
-
-
Asmolov, E.S.1
-
87
-
-
37649022478
-
Continuous inertial focusing, ordering, and separation of particles in microchannels
-
Di Carlo, D., Irimia, D., Tompkins, R.G. & Toner, M. Continuous inertial focusing, ordering, and separation of particles in microchannels. Proc. Natl. Acad. Sci. USA 104, 18892-18897 (2007
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 18892-18897
-
-
Di Carlo, D.1
Irimia, D.2
Tompkins, R.G.3
Toner, M.4
-
88
-
-
84864244832
-
High-yield cell ordering and deterministic cell-in-droplet encapsulation using Dean flow in a curved microchannel
-
Kemna, E.W.M. et al. High-yield cell ordering and deterministic cell-in-droplet encapsulation using Dean flow in a curved microchannel. Lab Chip 12, 2881-2887 (2012
-
(2012)
Lab Chip
, vol.12
, pp. 2881-2887
-
-
Kemna, E.W.M.1
-
89
-
-
0028167730
-
Iodixanol - A nonionic isosmotic centrifugation medium for the formation of self-generated gradients
-
Ford, T., Graham, J. & Rickwood, D. Iodixanol - a nonionic isosmotic centrifugation medium for the formation of self-generated gradients. Anal. Biochem. 220, 360-366 (1994
-
(1994)
Anal. Biochem
, vol.220
, pp. 360-366
-
-
Ford, T.1
Graham, J.2
Rickwood, D.3
-
90
-
-
77952388154
-
Use of iodixanol self-generated density gradients to enrich for viable urothelial cells from nonneurogenic and neurogenic bladder tissue
-
Bruce, A.T. et al. Use of iodixanol self-generated density gradients to enrich for viable urothelial cells from nonneurogenic and neurogenic bladder tissue. Tissue Eng. Part C Methods 16, 33-40 (2010
-
(2010)
Tissue Eng. Part C Methods
, vol.16
, pp. 33-40
-
-
Bruce, A.T.1
-
91
-
-
0030725671
-
A quick, easy and inexpensive method for the isolation of human peripheral blood monocytes
-
Graziani-Bowering, G.M., Graham, J.M. & Filion, L.G. A quick, easy and inexpensive method for the isolation of human peripheral blood monocytes. J. Immunol. Methods 207, 157-168 (1997
-
(1997)
J. Immunol. Methods
, vol.207
, pp. 157-168
-
-
Graziani-Bowering, G.M.1
Graham, J.M.2
Filion, L.G.3
-
94
-
-
79960637138
-
Statistical modeling of single target cell encapsulation
-
Moon, S., Ceyhan, E., Gurkan, U.A. & Demirci, U. Statistical modeling of single target cell encapsulation. PLoS ONE 6, e21580 (2011
-
(2011)
PLoS ONE
, vol.6
-
-
Moon, S.1
Ceyhan, E.2
Gurkan, U.A.3
Demirci, U.4
-
95
-
-
42149135990
-
Microfluidic high-throughput encapsulation and hydrodynamic self-sorting of single cells
-
Chabert, M. & Viovy, J.L. Microfluidic high-throughput encapsulation and hydrodynamic self-sorting of single cells. Proc. Natl. Acad. Sci. USA 105, 3191-3196 (2008
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 3191-3196
-
-
Chabert, M.1
Viovy, J.L.2
|