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Volumn 21, Issue 2, 2014, Pages 247-257

The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma

Author keywords

mantle cell lymphoma; transcription; Wnt signaling; ZEB1

Indexed keywords

BETA CATENIN; CYTARABINE; DOXORUBICIN; GEMCITABINE; SALINOMYCIN; TRANSCRIPTION FACTOR ZEB1; WNT PROTEIN; ANTINEOPLASTIC AGENT; HOMEODOMAIN PROTEIN; PYRAN DERIVATIVE; TRANSCRIPTION FACTOR; TUMOR MARKER; ZEB1 PROTEIN, HUMAN;

EID: 84892385077     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2013.123     Document Type: Article
Times cited : (102)

References (60)
  • 1
    • 84867163670 scopus 로고    scopus 로고
    • Molecular pathogenesis of mantle cell lymphoma
    • Jares P, Colomer D, Campo E. Molecular pathogenesis of mantle cell lymphoma. J Clin Invest 2012; 122: 3416-3423.
    • (2012) J Clin Invest , vol.122 , pp. 3416-3423
    • Jares, P.1    Colomer, D.2    Campo, E.3
  • 3
    • 24944592507 scopus 로고    scopus 로고
    • Gene expression profiling of mantle cell lymphoma cells reveals aberrant expression of genes from the PI3K-AKT, WNT and TGFβ signalling pathways
    • DOI 10.1111/j.1365-2141.2005.05630.x
    • Rizzatti EG, Falcão RP, Panepucci RA, Proto-Siqueira R, Anselmo-Lima WT, Okamoto OK et al. Gene expression profiling of mantle cell lymphoma cells reveals aberrant expression of genes from the PI3K-AKT, WNT and TGFb signalling pathways. Br J Haematol 2005; 130: 516-526. (Pubitemid 43899754)
    • (2005) British Journal of Haematology , vol.130 , Issue.4 , pp. 516-526
    • Rizzatti, E.G.1    Falcao, R.P.2    Panepucci, R.A.3    Proto-Siqueira, R.4    Anselmo-Lima, W.T.5    Okamoto, O.K.6    Zago, M.A.7
  • 4
    • 33846476267 scopus 로고    scopus 로고
    • Selective inhibition of IκB kinase sensitizes mantle cell lymphoma B cells to TRAIL by decreasing cellular FLIP level
    • Roué G, Pérez-Galán P, López-Guerra M, Villamor N, Campo E, Colomer D. Selective inhibition of IkappaB kinase sensitizes mantle cell lymphoma B cells to TRAIL by decreasing cellular FLIP level. J Immunol 2007; 178: 1923-1930. (Pubitemid 46154665)
    • (2007) Journal of Immunology , vol.178 , Issue.3 , pp. 1923-1930
    • Roue, G.1    Perez-Galan, P.2    Lopez-Guerra, M.3    Villamor, N.4    Campo, E.5    Colomer, D.6
  • 5
    • 58149382600 scopus 로고    scopus 로고
    • Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma
    • Gelebart P, Anand M, Armanious H, Peters AC, Dien Bard J, Amin HM et al. Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma. Blood 2008; 112: 5171-5179.
    • (2008) Blood , vol.112 , pp. 5171-5179
    • Gelebart, P.1    Anand, M.2    Armanious, H.3    Peters, A.C.4    Dien Bard, J.5    Amin, H.M.6
  • 6
    • 38949205610 scopus 로고    scopus 로고
    • Functionally associated targets in mantle cell lymphoma as defined by DNA microarrays and RNA interference
    • DOI 10.1182/blood-2007-02-068791
    • Ortega-Paino E, Fransson J, Ek S, Borrebaeck CA. Functionally associated targets in mantle cell lymphoma as defined by DNA microarrays and RNA interference. Blood 2008; 111: 1617-1624. (Pubitemid 351213453)
    • (2008) Blood , vol.111 , Issue.3 , pp. 1617-1624
    • Ortega-Paino, E.1    Fransson, J.2    Ek, S.3    Borrebaeck, C.A.K.4
  • 7
    • 77956525903 scopus 로고    scopus 로고
    • Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma
    • Leshchenko VV, Kuo PY, Shaknovich R, Yang DT, Gellen T, Petrich A et al. Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma. Blood 2010; 116: 1025-1034.
    • (2010) Blood , vol.116 , pp. 1025-1034
    • Leshchenko, V.V.1    Kuo, P.Y.2    Shaknovich, R.3    Yang, D.T.4    Gellen, T.5    Petrich, A.6
  • 8
    • 84879615395 scopus 로고    scopus 로고
    • The Wnt signaling pathway and mitotic regulators in the initiation and evolution of mantle cell lymphoma: Gene expression analysis
    • Kimura Y, Arakawa F, Kiyasu J, Miyoshi H, Yoshida M, Ichikawa A et al. The Wnt signaling pathway and mitotic regulators in the initiation and evolution of mantle cell lymphoma: gene expression analysis. Int J Oncol 2013; 43: 457-468.
    • (2013) Int J Oncol , vol.43 , pp. 457-468
    • Kimura, Y.1    Arakawa, F.2    Kiyasu, J.3    Miyoshi, H.4    Yoshida, M.5    Ichikawa, A.6
  • 9
    • 46749155539 scopus 로고    scopus 로고
    • Distinct functional significance of Akt and mTOR constitutive activation in mantle cell lymphoma
    • Dal Col J, Zancai P, Terrin L, Guidoboni M, Ponzoni M, Pavan A et al. Distinct functional significance of Akt and mTOR constitutive activation in mantle cell lymphoma. Blood 2008; 111: 5142-5151.
    • (2008) Blood , vol.111 , pp. 5142-5151
    • Dal Col, J.1    Zancai, P.2    Terrin, L.3    Guidoboni, M.4    Ponzoni, M.5    Pavan, A.6
  • 10
    • 0035437143 scopus 로고    scopus 로고
    • Altered apoptosis pathways in mantle cell lymphoma detected by oligonucleotide microarray
    • Hofmann WK, de Vos S, Tsukasaki K, Wachsman W, Pinkus GS, Said JW et al. Altered apoptosis pathways in mantle cell lymphoma detected by oligonucleotide microarray. Blood 2001; 98: 787-794.
    • (2001) Blood , vol.98 , pp. 787-794
    • Hofmann, W.K.1    De Vos, S.2    Tsukasaki, K.3    Wachsman, W.4    Pinkus, G.S.5    Said, J.W.6
  • 14
    • 77950287628 scopus 로고    scopus 로고
    • The Wnt/b-catenin pathway is required for the development of leukemia stem cells in AML
    • Wang Y, Krivtsov AV, Sinha AU, North TE, Goessling W, Feng Z et al. The Wnt/b-catenin pathway is required for the development of leukemia stem cells in AML. Science 2010; 327: 1650-1653.
    • (2010) Science , vol.327 , pp. 1650-1653
    • Wang, Y.1    Krivtsov, A.V.2    Sinha, A.U.3    North, T.E.4    Goessling, W.5    Feng, Z.6
  • 16
    • 80052012674 scopus 로고    scopus 로고
    • Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells
    • Lu D, Choi MY, Yu J, Castro JE, Kipps TJ, Carson DA. Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells. Proc Natl Acad Sci USA 2011; 108: 13253-13257.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 13253-13257
    • Lu, D.1    Choi, M.Y.2    Yu, J.3    Castro, J.E.4    Kipps, T.J.5    Carson, D.A.6
  • 17
    • 33847187070 scopus 로고    scopus 로고
    • Novel etodolac analog SDX-308 (CEP-18082) induces cytotoxicity in multiple myeloma cells associated with inhibition of b-catenin/TCF pathway
    • Yasui H, Hideshima T, Ikeda H, Ocio EM, Kiziltepe T, Vallet S et al. Novel etodolac analog SDX-308 (CEP-18082) induces cytotoxicity in multiple myeloma cells associated with inhibition of b-catenin/TCF pathway. Leukemia 2007; 21: 535-540.
    • (2007) Leukemia , vol.21 , pp. 535-540
    • Yasui, H.1    Hideshima, T.2    Ikeda, H.3    Ocio, E.M.4    Kiziltepe, T.5    Vallet, S.6
  • 18
    • 34447126400 scopus 로고    scopus 로고
    • Activation of Wnt/β-catenin pathway mediates growth and survival in B-cell progenitor acute lymphoblastic leukaemia
    • DOI 10.1111/j.1365-2141.2007.06667.x
    • Khan NI, Bradstock KF, Bendall LJ. Activation of Wnt/b-catenin pathway mediates growth and survival in B-cell progenitor acute lymphoblastic leukaemia. Br J Haematol 2007; 138: 338-348. (Pubitemid 47035396)
    • (2007) British Journal of Haematology , vol.138 , Issue.3 , pp. 338-348
    • Khan, N.I.1    Bradstock, K.F.2    Bendall, L.J.3
  • 21
    • 70349311852 scopus 로고    scopus 로고
    • Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia
    • Valencia A, Román-Gómez J, Cervera J, Such E, Barragán E, Bolufer P et al. Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia. Leukemia 2009; 23: 1658-1666.
    • (2009) Leukemia , vol.23 , pp. 1658-1666
    • Valencia, A.1    Román-Gómez, J.2    Cervera, J.3    Such, E.4    Barragán, E.5    Bolufer, P.6
  • 22
    • 70349560308 scopus 로고    scopus 로고
    • How i treat mantle cell lymphoma
    • Ghielmini M, Zucca E. How I treat mantle cell lymphoma. Blood 2009; 114: 1469-1476.
    • (2009) Blood , vol.114 , pp. 1469-1476
    • Ghielmini, M.1    Zucca, E.2
  • 23
    • 84875594520 scopus 로고    scopus 로고
    • ESMO Consensus conferences: Guidelines on malignant lymphoma. Part 2: Marginal zone lymphoma, mantle cell lymphoma, peripheral T-cell lymphoma
    • Dreyling M, Thieblemont C, Gallamini A, Arcaini L, Campo E, Hermine O et al. ESMO Consensus conferences: guidelines on malignant lymphoma. Part 2: marginal zone lymphoma, mantle cell lymphoma, peripheral T-cell lymphoma. Ann Oncol 2013; 24: 857-877.
    • (2013) Ann Oncol , vol.24 , pp. 857-877
    • Dreyling, M.1    Thieblemont, C.2    Gallamini, A.3    Arcaini, L.4    Campo, E.5    Hermine, O.6
  • 24
    • 79957500293 scopus 로고    scopus 로고
    • Stem-like tumor cells confer drug resistant properties to mantle cell lymphoma
    • Jung HJ, Chen Z, McCarty N. Stem-like tumor cells confer drug resistant properties to mantle cell lymphoma. Leuk Lymphoma 2011; 52: 1066-1079.
    • (2011) Leuk Lymphoma , vol.52 , pp. 1066-1079
    • Jung, H.J.1    Chen, Z.2    McCarty, N.3
  • 25
    • 68749099671 scopus 로고    scopus 로고
    • Identification of selective inhibitors of cancer stem cells by high-throughput screening
    • Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RA et al. Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 2009; 138: 645-659.
    • (2009) Cell , vol.138 , pp. 645-659
    • Gupta, P.B.1    Onder, T.T.2    Jiang, G.3    Tao, K.4    Kuperwasser, C.5    Weinberg, R.A.6
  • 26
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/b-catenin signaling and disease
    • Clevers H, Nusse R. Wnt/b-Catenin Signaling and Disease. Cell 2012; 149: 1192-1205.
    • (2012) Cell , vol.149 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 27
    • 33748116186 scopus 로고    scopus 로고
    • A Transient, emt-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer
    • DOI 10.1053/j.gastro.2006.06.016, PII S0016508506012868
    • Spaderna S, Schmalhofer O, Hlubek F, Berx G, Eger A, Merkel S et al. A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer. Gastroenterology 2006; 131: 830-840. (Pubitemid 44307069)
    • (2006) Gastroenterology , vol.131 , Issue.3 , pp. 830-840
    • Spaderna, S.1    Schmalhofer, O.2    Hlubek, F.3    Berx, G.4    Eger, A.5    Merkel, S.6    Jung, A.7    Kirchner, T.8    Brabletz, T.9
  • 28
    • 73049110243 scopus 로고    scopus 로고
    • The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting micro-RNAs
    • Wellner U, Schubert J, Burk UC, Schmalhofer O, Zhu F, Sonntag A et al. The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting micro-RNAs. Nat Cell Biol 2009; 11: 1487-1495.
    • (2009) Nat Cell Biol , vol.11 , pp. 1487-1495
    • Wellner, U.1    Schubert, J.2    Burk, U.C.3    Schmalhofer, O.4    Zhu, F.5    Sonntag, A.6
  • 29
    • 77953743748 scopus 로고    scopus 로고
    • ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatinremodeling protein BRG1
    • Sanchez-Tillo E, Lazaro A, Torrent R, Cuatrecasas M, Vaquero EC, Castells A et al. ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatinremodeling protein BRG1. Oncogene 2010; 29: 3490-3500.
    • (2010) Oncogene , vol.29 , pp. 3490-3500
    • Sanchez-Tillo, E.1    Lazaro, A.2    Torrent, R.3    Cuatrecasas, M.4    Vaquero, E.C.5    Castells, A.6
  • 30
    • 82755198488 scopus 로고    scopus 로고
    • Postigo A. B-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness
    • Sanchez-Tillo E, de Barrios O, Siles L, Cuatrecasas M, Castells A, Postigo A. b-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness. Proc Natl Acad Sci USA 2011; 108: 19204-19209.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 19204-19209
    • Sanchez-Tillo, E.1    De Barrios, O.2    Siles, L.3    Cuatrecasas, M.4    Castells, A.5
  • 31
  • 34
    • 0038324070 scopus 로고    scopus 로고
    • Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins
    • DOI 10.1093/emboj/cdg226
    • Postigo A, Depp JL, Taylor JJ, Kroll KL.Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins. EMBO J 2003; 22: 2453-2462. (Pubitemid 36604984)
    • (2003) EMBO Journal , vol.22 , Issue.10 , pp. 2453-2462
    • Postigo, A.A.1    Depp, J.L.2    Taylor, J.J.3    Kroll, K.L.4
  • 36
    • 84873050284 scopus 로고    scopus 로고
    • Regulatory networks defining EMT during cancer initiation and progression
    • De Craene B, Berx G. Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer 2013; 13: 97-110.
    • (2013) Nat Rev Cancer , vol.13 , pp. 97-110
    • De Craene, B.1    Berx, G.2
  • 37
    • 84871385387 scopus 로고    scopus 로고
    • ZEB/miR-200 feedback loop: At the crossroads of signal transduction in cancer
    • Hill L, Browne G, Tulchinsky E. ZEB/miR-200 feedback loop: at the crossroads of signal transduction in cancer. Int J Cancer 2013; 132: 745-754.
    • (2013) Int J Cancer , vol.132 , pp. 745-754
    • Hill, L.1    Browne, G.2    Tulchinsky, E.3
  • 41
    • 47349092050 scopus 로고    scopus 로고
    • Explorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis
    • Blenk S, Engelmann JC, Pinkert S, Weniger M, Schultz J, Rosenwald A et al. Explorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis. BMC Cancer 2008; 8: 106.
    • (2008) BMC Cancer , vol.8 , pp. 106
    • Blenk, S.1    Engelmann, J.C.2    Pinkert, S.3    Weniger, M.4    Schultz, J.5    Rosenwald, A.6
  • 42
    • 0034282097 scopus 로고    scopus 로고
    • Nuclear-cytoplasmic shuttling of APC regulates b-catenin subcellular localization and turnover
    • Henderson BR. Nuclear-cytoplasmic shuttling of APC regulates b-catenin subcellular localization and turnover. Nat Cell Biol 2000; 2: 653-660.
    • (2000) Nat Cell Biol , vol.2 , pp. 653-660
    • Henderson, B.R.1
  • 44
    • 34250028203 scopus 로고    scopus 로고
    • Inactivation of RB1 in mantle-cell lymphoma detected by nonsense-mediated mRNA decay pathway inhibition and microarray analysis
    • DOI 10.1182/blood-2006-11-057208
    • Pinyol M, Bea S, Pla L, Ribrag V, Bosq J, Rosenwald A et al. Inactivation of Rb1 in mantlecell lymphoma detected by nonsense-mediated mRNA decay pathway inhibition and microarray analysis. Blood 2007; 109: 5422-5429. (Pubitemid 46890565)
    • (2007) Blood , vol.109 , Issue.12 , pp. 5422-5429
    • Pinyol, M.1    Bea, S.2    Pla, L.3    Ribrag, V.4    Bosq, J.5    Rosenwald, A.6    Campo, E.7    Jares, P.8
  • 45
    • 0038324071 scopus 로고    scopus 로고
    • Opposing functions of ZEB proteins in the regulation of the TGFβ/BMP signaling pathway
    • DOI 10.1093/emboj/cdg225
    • Postigo A. Opposing functions of ZEB proteins in the regulation of the TGFb/BMP signaling pathway. EMBO J 2003; 22: 2443-2452. (Pubitemid 36604983)
    • (2003) EMBO Journal , vol.22 , Issue.10 , pp. 2443-2452
    • Postigo, A.A.1
  • 47
    • 41649109459 scopus 로고    scopus 로고
    • Zeb1 links epithelial-mesenchymal transition and cellular senescence
    • Liu Y, El-Naggar S, Darling DS, Higashi Y, Dean DC. Zeb1 links epithelial-mesenchymal transition and cellular senescence. Development 2008; 135: 579-588.
    • (2008) Development , vol.135 , pp. 579-588
    • Liu, Y.1    El-Naggar, S.2    Darling, D.S.3    Higashi, Y.4    Dean, D.C.5
  • 48
    • 0036660406 scopus 로고    scopus 로고
    • Ki-67 expression level, histological subtype, and the International Prognostic Index as outcome predictors in mantle cell lymphoma
    • DOI 10.1034/j.1600-0609.2002.01677.x
    • Rä ty R, Franssila K, Joensuu H, Teerenhovi L, Elonen E. Ki-67 expression level, histological subtype, and the International Prognostic Index as outcome predictors in mantle cell lymphoma. Eur J Haematol 2002; 69: 11-20. (Pubitemid 35155435)
    • (2002) European Journal of Haematology , vol.69 , Issue.1 , pp. 11-20
    • Raty, R.1    Franssila, K.2    Joensuu, H.3    Teerenhovi, L.4    Elonen, E.5
  • 49
    • 54449085259 scopus 로고    scopus 로고
    • Five-gene model to predict survival in mantle-cell lymphoma using frozen or formalin-fixed, paraffinembedded tissue
    • Hartmann E, Fernandez V, Moreno V, Valls J, Hernandez L, Bosch F et al. Five-gene model to predict survival in mantle-cell lymphoma using frozen or formalin-fixed, paraffinembedded tissue. J Clin Oncol 2008; 26: 4966-4972.
    • (2008) J Clin Oncol , vol.26 , pp. 4966-4972
    • Hartmann, E.1    Fernandez, V.2    Moreno, V.3    Valls, J.4    Hernandez, L.5    Bosch, F.6
  • 51
    • 33947396419 scopus 로고    scopus 로고
    • Pharmacogenetics/genomics of membrane transporters in cancer chemotherapy
    • DOI 10.1007/s10555-007-9050-6, Special Issue on Transporters in Cancer
    • Huang Y. Pharmacogenetics/genomics of membrane transporters in cancer chemotherapy. Cancer Metastasis Rev 2007; 26: 183-201. (Pubitemid 46452190)
    • (2007) Cancer and Metastasis Reviews , vol.26 , Issue.1 , pp. 183-201
    • Huang, Y.1
  • 53
    • 33745792969 scopus 로고    scopus 로고
    • Expression of human equilibrative nucleoside transporter 1 (hENT1) and its correlation with gemcitabine uptake and cytotoxicity in mantle cell lymphoma
    • Marce S, Molina-Arcas M, Villamor N, Casado FJ, Campo E, Pastor-Anglada M et al. Expression of human equilibrative nucleoside transporter 1 (hENT1) and its correlation with gemcitabine uptake and cytotoxicity in mantle cell lymphoma. Haematologica 2006; 91: 895-902. (Pubitemid 44023142)
    • (2006) Haematologica , vol.91 , Issue.7 , pp. 895-902
    • Marce, S.1    Molina-Arcas, M.2    Villamor, N.3    Casado, F.J.4    Campo, E.5    Pastor-Anglada, M.6    Colomer, D.7
  • 54
    • 76549129820 scopus 로고    scopus 로고
    • Drug combination studies and their synergy quantification using the Chou-Talalay method
    • Chou TC. Drug combination studies and their synergy quantification using the Chou-Talalay method. Cancer Res 2010; 70: 440-446.
    • (2010) Cancer Res , vol.70 , pp. 440-446
    • Chou, T.C.1
  • 56
    • 64249136718 scopus 로고    scopus 로고
    • Uniparental disomies, homozygous deletions, amplifications, and target genes in mantle cell lymphoma revealed by integrative high-resolution whole-genome profiling
    • Bea S, Salaverria I, Armengol L, Pinyol M, Fernández V, Hartmann EM et al. Uniparental disomies, homozygous deletions, amplifications, and target genes in mantle cell lymphoma revealed by integrative high-resolution whole-genome profiling. Blood 2009; 113: 3059-3069.
    • (2009) Blood , vol.113 , pp. 3059-3069
    • Bea, S.1    Salaverria, I.2    Armengol, L.3    Pinyol, M.4    Fernández, V.5    Hartmann, E.M.6
  • 58
    • 84863938543 scopus 로고    scopus 로고
    • Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors
    • Gurney A, Axelrod F, Bond CJ, Cain J, Chartier C, Donigan L et al. Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors. Proc Natl Acad Sci USA 2012; 109: 11717-11722.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 11717-11722
    • Gurney, A.1    Axelrod, F.2    Bond, C.J.3    Cain, J.4    Chartier, C.5    Donigan, L.6
  • 59
    • 84871846692 scopus 로고    scopus 로고
    • WNT signalling pathways as therapeutic targets in cancer
    • Anastas JN, Moon RT. WNT signalling pathways as therapeutic targets in cancer. Nat Rev Cancer 2013; 13: 11-26.
    • (2013) Nat Rev Cancer , vol.13 , pp. 11-26
    • Anastas, J.N.1    Moon, R.T.2


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