메뉴 건너뛰기




Volumn 122, Issue 10, 2012, Pages 3416-3423

Molecular pathogenesis of mantle cell lymphoma

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 AMINO 5 (7 METHOXY 1H INDOL 2 YL)IMIDAZO[5,1 F][1,2,4]TRIAZIN 7 YL)CYCLOHEXANECARBOXYLIC ACID; 6 ACETYL 8 CYCLOPENTYL 5 METHYL 2 [5 (1 PIPERAZINYL) 2 PYRIDINYLAMINO] 8H PYRIDO[2,3 D]PYRIMIDIN 7 ONE; 8 [4 (1 AMINOCYCLOBUTYL)PHENYL] 9 PHENYL 1,2,4 TRIAZOLO[3,4 F][1,6]NAPHTHYRIDIN 3(2H) ONE; BORTEZOMIB; CARFILZOMIB; CYCLIN D1; EVEROLIMUS; FLAVOPIRIDOL; IBRUTINIB; IDELALISIB; IXAZOMIB CITRATE; NOTCH1 RECEPTOR; PACRITINIB; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RUCAPARIB; SALINOSPORAMIDE A; STAT3 PROTEIN; TEMSIROLIMUS; TRANSCRIPTION FACTOR SOX11;

EID: 84867163670     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI61272     Document Type: Review
Times cited : (310)

References (115)
  • 1
    • 34648824397 scopus 로고    scopus 로고
    • Genetic and molecular pathogenesis of mantle cell lymphoma: Perspectives for new targeted therapeutics
    • DOI 10.1038/nrc2230, PII NRC2230
    • Jares P, Colomer D, Campo E. Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics. Nat Rev Cancer. 2007;7(10):750-762. (Pubitemid 47463673)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.10 , pp. 750-762
    • Jares, P.1    Colomer, D.2    Campo, E.3
  • 2
    • 47349126802 scopus 로고    scopus 로고
    • Advances in the understanding of mantle cell lymphoma
    • DOI 10.1111/j.1365-2141.2008.07124.x
    • Jares P, Campo E. Advances in the understanding of mantle cell lymphoma. Br J Haematol. 2008;142(2):149-165. (Pubitemid 351994053)
    • (2008) British Journal of Haematology , vol.142 , Issue.2 , pp. 149-165
    • Jares, P.1    Campo, E.2
  • 3
    • 50949125416 scopus 로고    scopus 로고
    • Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma
    • Chen RW, et al. Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma. Blood. 2008;112(3):822-829.
    • (2008) Blood , vol.112 , Issue.3 , pp. 822-829
    • Chen, R.W.1
  • 5
    • 84865839816 scopus 로고    scopus 로고
    • The impact of cyclin D1 mRNA isoforms, morphology and p53 in mantle cell lymphoma: P53 alterations and blastoid morphology are strong predictors of a high proliferation index
    • Slotta-Huspenina J, et al. The impact of cyclin D1 mRNA isoforms, morphology and p53 in mantle cell lymphoma: p53 alterations and blastoid morphology are strong predictors of a high proliferation index. Haematologica. 2012;97(9):1422-1430.
    • (2012) Haematologica , vol.97 , Issue.9 , pp. 1422-1430
    • Slotta-Huspenina, J.1
  • 6
    • 64249136718 scopus 로고    scopus 로고
    • Uniparental disomies, homozygous deletions, amplifications, and target genes in mantle cell lymphoma revealed by integrative high-resolution whole-genome profiling
    • Bea S, et al. Uniparental disomies, homozygous deletions, amplifications, and target genes in mantle cell lymphoma revealed by integrative high-resolution whole-genome profiling. Blood. 2009;113(13):3059-3069.
    • (2009) Blood , vol.113 , Issue.13 , pp. 3059-3069
    • Bea, S.1
  • 10
    • 80052929598 scopus 로고    scopus 로고
    • Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases
    • Hadzidimitriou A, et al. Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases. Blood. 2011;118(11):3088-3095.
    • (2011) Blood , vol.118 , Issue.11 , pp. 3088-3095
    • Hadzidimitriou, A.1
  • 11
    • 33947195990 scopus 로고    scopus 로고
    • A novel human B cell subpopulation representing the initial germinal center population to express AID
    • DOI 10.1182/blood-2006-07-037150
    • Kolar GR, Mehta D, Pelayo R, Capra JD. A novel human B cell subpopulation representing the initial germinal center population to express AID. Blood. 2007;109(6):2545-2552. (Pubitemid 46425900)
    • (2007) Blood , vol.109 , Issue.6 , pp. 2545-2552
    • Kolar, G.R.1    Mehta, D.2    Pelayo, R.3    Capra, J.D.4
  • 12
    • 19344376101 scopus 로고    scopus 로고
    • Identification and characterization of circulating human transitional B cells
    • DOI 10.1182/blood-2004-11-4284
    • Sims GP, Ettinger R, Shirota Y, Yarboro CH, Illei GG, Lipsky PE. Identification and characterization of circulating human transitional B cells. Blood. 2005;105(11):4390-4398. (Pubitemid 40720786)
    • (2005) Blood , vol.105 , Issue.11 , pp. 4390-4398
    • Sims, G.P.1    Ettinger, R.2    Shirota, Y.3    Yarboro, C.H.4    Illei, G.G.5    Lipsky, P.E.6
  • 13
    • 9444236895 scopus 로고    scopus 로고
    • Minireview: Cyclin D1: Normal and abnormal functions
    • DOI 10.1210/en.2004-0959
    • Fu M, Wang C, Li Z, Sakamaki T, Pestell RG. Mini-review: Cyclin D1: normal and abnormal functions. Endocrinology. 2004;145(12):5439-5447. (Pubitemid 39564581)
    • (2004) Endocrinology , vol.145 , Issue.12 , pp. 5439-5447
    • Fu, M.1    Wang, C.2    Li, Z.3    Sakamaki, T.4    Pestell, R.G.5
  • 14
    • 77957966270 scopus 로고    scopus 로고
    • Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase
    • Aggarwal P, et al. Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase. Cancer Cell. 2010;18(4):329-340.
    • (2010) Cancer Cell , vol.18 , Issue.4 , pp. 329-340
    • Aggarwal, P.1
  • 15
    • 75149175161 scopus 로고    scopus 로고
    • Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen
    • Bienvenu F, et al. Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen. Nature. 2010;463(7279):374-378.
    • (2010) Nature , vol.463 , Issue.7279 , pp. 374-378
    • Bienvenu, F.1
  • 16
    • 84863256545 scopus 로고    scopus 로고
    • ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice
    • Casimiro MC, et al. ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice. J Clin Invest. 2012;122(3):833-843.
    • (2012) J Clin Invest , vol.122 , Issue.3 , pp. 833-843
    • Casimiro, M.C.1
  • 17
    • 79958254560 scopus 로고    scopus 로고
    • A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers
    • Jirawatnotai S, et al. A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers. Nature. 2011;474(7350):230- 234.
    • (2011) Nature , vol.474 , Issue.7350 , pp. 230-234
    • Jirawatnotai, S.1
  • 18
    • 79958265685 scopus 로고    scopus 로고
    • DNA repair: Cyclin D1 multi-tasks
    • Bartek J, Lukas J. DNA repair: Cyclin D1 multi-tasks. Nature. 2011;474(7350):171-172.
    • (2011) Nature , vol.474 , Issue.7350 , pp. 171-172
    • Bartek, J.1    Lukas, J.2
  • 19
    • 34250028203 scopus 로고    scopus 로고
    • Inactivation of RB1 in mantle-cell lymphoma detected by nonsense-mediated mRNA decay pathway inhibition and microarray analysis
    • DOI 10.1182/blood-2006-11-057208
    • Pinyol M, et al. Inactivation of RB1 in mantle-cell lymphoma detected by nonsense-mediated mRNA decay pathway inhibition and microarray analysis. Blood. 2007;109(12):5422-5429. (Pubitemid 46890565)
    • (2007) Blood , vol.109 , Issue.12 , pp. 5422-5429
    • Pinyol, M.1    Bea, S.2    Pla, L.3    Ribrag, V.4    Bosq, J.5    Rosenwald, A.6    Campo, E.7    Jares, P.8
  • 20
    • 79961079532 scopus 로고    scopus 로고
    • A cyclin-D1 interaction with BAX underlies its oncogenic role and potential as a therapeutic target in mantle cell lymphoma
    • Beltran E, et al. A cyclin-D1 interaction with BAX underlies its oncogenic role and potential as a therapeutic target in mantle cell lymphoma. Proc Natl Acad Sci U S A. 2011;108(30):12461-12466.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.30 , pp. 12461-12466
    • Beltran, E.1
  • 25
    • 0036090306 scopus 로고    scopus 로고
    • ATM gene inactivation in mantle cell lymphoma mainly occurs by truncating mutations and missense mutations involving the phosphatidylinositol-3 kinase domain and is associated with increasing numbers of chromosomal imbalances
    • Camacho E, et al. ATM gene inactivation in mantle cell lymphoma mainly occurs by truncating mutations and missense mutations involving the phosphatidylinositol-3 kinase domain and is associated with increasing numbers of chromosomal imbalances. Blood. 2002;99(1):238-244.
    • (2002) Blood , vol.99 , Issue.1 , pp. 238-244
    • Camacho, E.1
  • 26
    • 77956540011 scopus 로고    scopus 로고
    • Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling
    • Hartmann EM, et al. Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling. Blood. 2010;116(6):953-961.
    • (2010) Blood , vol.116 , Issue.6 , pp. 953-961
    • Hartmann, E.M.1
  • 27
    • 84857763426 scopus 로고    scopus 로고
    • Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma
    • Kridel R, et al. Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma. Blood. 2012;119(9):1963-1971.
    • (2012) Blood , vol.119 , Issue.9 , pp. 1963-1971
    • Kridel, R.1
  • 28
    • 79960036578 scopus 로고    scopus 로고
    • Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
    • Puente XS, et al. Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. Nature. 2011;475(7354):101-105.
    • (2011) Nature , vol.475 , Issue.7354 , pp. 101-105
    • Puente, X.S.1
  • 29
    • 79960353160 scopus 로고    scopus 로고
    • Analysis of the chronic lymphocytic leukemia coding genome: Role of NOTCH1 mutational activation
    • Fabbri G, et al. Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation. J Exp Med. 2011;208(7):1389-1401.
    • (2011) J Exp Med , vol.208 , Issue.7 , pp. 1389-1401
    • Fabbri, G.1
  • 31
    • 84873984021 scopus 로고    scopus 로고
    • Clinicopathologic characterization of cyclin D1-negative mantle cell lymphoma
    • Carvajal-Cuenca A, et al. Clinicopathologic characterization of cyclin D1-negative mantle cell lymphoma. Mod Pathol. 2012;25:1370.
    • (2012) Mod Pathol , vol.25 , pp. 1370
    • Carvajal-Cuenca, A.1
  • 32
    • 38349103985 scopus 로고    scopus 로고
    • Nuclear expression of the non B-cell lineage Sox11 transcription factor identifies mantle cell lymphoma
    • Ek S, Dictor M, Jerkeman M, Jirstrom K, Borrebaeck CA. Nuclear expression of the non B-cell lineage Sox11 transcription factor identifies mantle cell lymphoma. Blood. 2008;111(2):800-805.
    • (2008) Blood , vol.111 , Issue.2 , pp. 800-805
    • Ek, S.1    Dictor, M.2    Jerkeman, M.3    Jirstrom, K.4    Borrebaeck, C.A.5
  • 33
    • 70449435195 scopus 로고    scopus 로고
    • SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype
    • Mozos A, et al. SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype. Haematologica. 2009;94(11):1555-1562.
    • (2009) Haematologica , vol.94 , Issue.11 , pp. 1555-1562
    • Mozos, A.1
  • 34
    • 79959622257 scopus 로고    scopus 로고
    • Epigenetic activation of SOX11 in lymphoid neoplasms by histone modifications
    • Vegliante MC, et al. Epigenetic activation of SOX11 in lymphoid neoplasms by histone modifications. PLoS One. 2011;6(6):e21382.
    • (2011) PLoS One , vol.6 , Issue.6
    • Vegliante, M.C.1
  • 35
    • 46749155539 scopus 로고    scopus 로고
    • Distinct functional significance of Akt and mTOR constitutive activation in mantle cell lymphoma
    • Dal Col J, et al. Distinct functional significance of Akt and mTOR constitutive activation in mantle cell lymphoma. Blood. 2008;111(10):5142-5151.
    • (2008) Blood , vol.111 , Issue.10 , pp. 5142-5151
    • Dal Col, J.1
  • 38
    • 70149118546 scopus 로고    scopus 로고
    • MicroRNA expression, chromosomal alterations, and immunoglobulin variable heavy chain hypermutations in Mantle cell lymphomas
    • Navarro A, et al. MicroRNA expression, chromosomal alterations, and immunoglobulin variable heavy chain hypermutations in Mantle cell lymphomas. Cancer Res. 2009;69(17):7071-7078.
    • (2009) Cancer Res , vol.69 , Issue.17 , pp. 7071-7078
    • Navarro, A.1
  • 39
    • 84860755726 scopus 로고    scopus 로고
    • The miRNA-17 approximately 92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation
    • Rao E, et al. The miRNA-17 approximately 92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation. Leukemia. 2012;26(5):1064-1072.
    • (2012) Leukemia , vol.26 , Issue.5 , pp. 1064-1072
    • Rao, E.1
  • 41
    • 70349454210 scopus 로고    scopus 로고
    • Phosphatidylinositol 3′-kinase catalytic subunit alpha gene amplification contributes to the pathogenesis of mantle cell lymphoma
    • Psyrri A, et al. Phosphatidylinositol 3′-kinase catalytic subunit alpha gene amplification contributes to the pathogenesis of mantle cell lymphoma. Clin Cancer Res. 2009;15(18):5724-5732.
    • (2009) Clin Cancer Res , vol.15 , Issue.18 , pp. 5724-5732
    • Psyrri, A.1
  • 42
    • 79960917689 scopus 로고    scopus 로고
    • Phospho-proteomic analysis of mantle cell lymphoma cells suggests a pro-survival role of B-cell receptor signaling
    • Pighi C, et al. Phospho-proteomic analysis of mantle cell lymphoma cells suggests a pro-survival role of B-cell receptor signaling. Cell Oncol (Dordr). 2011;34(2):141-153.
    • (2011) Cell Oncol (Dordr) , vol.34 , Issue.2 , pp. 141-153
    • Pighi, C.1
  • 43
    • 78149266421 scopus 로고    scopus 로고
    • Constitutive and B-cell receptor-induced activation of STAT3 are important signaling pathways targeted by bortezomib in leukemic mantle cell lymphoma
    • Baran-Marszak F, et al. Constitutive and B-cell receptor-induced activation of STAT3 are important signaling pathways targeted by bortezomib in leukemic mantle cell lymphoma. Haematologica. 2010;95(11):1865-1872.
    • (2010) Haematologica , vol.95 , Issue.11 , pp. 1865-1872
    • Baran-Marszak, F.1
  • 44
    • 0037220899 scopus 로고    scopus 로고
    • Expression of STAT3 and its phosphorylated forms in mantle cell lymphoma cell lines and tumours
    • DOI 10.1002/path.1253
    • Lai R, Rassidakis GZ, Medeiros LJ, Leventaki V, Keating M, McDonnell TJ. Expression of STAT3 and its phosphorylated forms in mantle cell lymphoma cell lines and tumours. J Pathol. 2003;199(1):84-89. (Pubitemid 36054732)
    • (2003) Journal of Pathology , vol.199 , Issue.1 , pp. 84-89
    • Lai, R.1    Rassidakis, G.Z.2    Medeiros, L.J.3    Leventaki, V.4    Keating, M.5    McDonnell, T.J.6
  • 46
    • 0033874078 scopus 로고    scopus 로고
    • Mantle cell lymphoma proliferates upon IL-10 in the CD40 system
    • Visser HP, Tewis M, Willemze R, Kluin-Nelemans JC. Mantle cell lymphoma proliferates upon IL-10 in the CD40 system. Leukemia. 2000;14(8):1483-1489. (Pubitemid 30599329)
    • (2000) Leukemia , vol.14 , Issue.8 , pp. 1483-1489
    • Visser, H.P.J.1    Tewis, M.2    Willemze, R.3    Kluin-Nelemans, J.C.4
  • 47
    • 73349141714 scopus 로고    scopus 로고
    • Inactivating SOCS1 mutations are caused by aberrant somatic hypermutation and restricted to a subset of B-cell lymphoma entities
    • Mottok A, et al. Inactivating SOCS1 mutations are caused by aberrant somatic hypermutation and restricted to a subset of B-cell lymphoma entities. Blood. 2009;114(20):4503-4506.
    • (2009) Blood , vol.114 , Issue.20 , pp. 4503-4506
    • Mottok, A.1
  • 48
    • 0034665893 scopus 로고    scopus 로고
    • Soluble CD40 ligand induces selective proliferation of lymphoma cells in primary mantle cell lymphoma cell cultures
    • Andersen NS, et al. Soluble CD40 ligand induces selective proliferation of lymphoma cells in primary mantle cell lymphoma cell cultures. Blood. 2000;96(6):2219-2225.
    • (2000) Blood , vol.96 , Issue.6 , pp. 2219-2225
    • Andersen, N.S.1
  • 49
    • 82555165949 scopus 로고    scopus 로고
    • The microenvironment in mantle cell lymphoma: Cellular and molecular pathways and emerging targeted therapies
    • Burger JA, Ford RJ. The microenvironment in mantle cell lymphoma: cellular and molecular pathways and emerging targeted therapies. Semin Cancer Biol. 2011;21(5):308-312.
    • (2011) Semin Cancer Biol , vol.21 , Issue.5 , pp. 308-312
    • Burger, J.A.1    Ford, R.J.2
  • 50
    • 66549113998 scopus 로고    scopus 로고
    • Mantle cell lymphoma cells express high levels of CXCR4, CXCR5, and VLA-4 (CD49d): Importance for interactions with the stromal microenvironment and specific targeting
    • Kurtova AV, Tamayo AT, Ford RJ, Burger JA. Mantle cell lymphoma cells express high levels of CXCR4, CXCR5, and VLA-4 (CD49d): importance for interactions with the stromal microenvironment and specific targeting. Blood. 2009;113(19):4604-4613.
    • (2009) Blood , vol.113 , Issue.19 , pp. 4604-4613
    • Kurtova, A.V.1    Tamayo, A.T.2    Ford, R.J.3    Burger, J.A.4
  • 51
    • 79251578072 scopus 로고    scopus 로고
    • Interleukin 22 signaling promotes cell growth in mantle cell lymphoma
    • Gelebart P, Zak Z, en-Bard J, Anand M, Lai R. Interleukin 22 signaling promotes cell growth in mantle cell lymphoma. Transl Oncol. 2011;4(1):9-19.
    • (2011) Transl Oncol , vol.4 , Issue.1 , pp. 9-19
    • Gelebart, P.1    Zak, Z.2    En-Bard, J.3    Anand, M.4    Lai, R.5
  • 52
    • 33846476267 scopus 로고    scopus 로고
    • Selective inhibition of IkappaB kinase sensitizes mantle cell lymphoma B cells to TRAIL by decreasing cellular FLIP level
    • Roue G, Perez-Galan P, Lopez-Guerra M, Villamor N, Campo E, Colomer D. Selective inhibition of IkappaB kinase sensitizes mantle cell lymphoma B cells to TRAIL by decreasing cellular FLIP level. J Immunol. 2007;178(3):1923-1930. (Pubitemid 46154665)
    • (2007) Journal of Immunology , vol.178 , Issue.3 , pp. 1923-1930
    • Roue, G.1    Perez-Galan, P.2    Lopez-Guerra, M.3    Villamor, N.4    Campo, E.5    Colomer, D.6
  • 53
    • 0038206722 scopus 로고    scopus 로고
    • Inhibition of constitutive NF-kappaB activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis
    • Pham L V, Tamayo AT, Yoshimura LC, Lo P, Ford RJ. Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis. J Immunol. 2003;171(1):88-95. (Pubitemid 36745276)
    • (2003) Journal of Immunology , vol.171 , Issue.1 , pp. 88-95
    • Pham, L.V.1    Tamayo, A.T.2    Yoshimura, L.C.3    Lo, P.4    Ford, R.J.5
  • 54
    • 70350504882 scopus 로고    scopus 로고
    • TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas
    • Honma K, et al. TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas. Blood. 2009;114(12):2467-2475.
    • (2009) Blood , vol.114 , Issue.12 , pp. 2467-2475
    • Honma, K.1
  • 55
    • 58149382600 scopus 로고    scopus 로고
    • Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma
    • Gelebart P, et al. Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma. Blood. 2008;112(13):5171-5179.
    • (2008) Blood , vol.112 , Issue.13 , pp. 5171-5179
    • Gelebart, P.1
  • 56
    • 84862194194 scopus 로고    scopus 로고
    • Outcome of deferred initial therapy in mantle-cell lymphoma
    • Martin P, et al. Outcome of deferred initial therapy in mantle-cell lymphoma. J Clin Oncol. 2009;27(8):1209-1213.
    • (2009) J Clin Oncol , vol.27 , Issue.8 , pp. 1209-1213
    • Martin, P.1
  • 57
    • 73949116793 scopus 로고    scopus 로고
    • Time to treatment does not influence overall survival in newly diagnosed mantle-cell lymphoma
    • Eve HE, Furtado MV, Hamon MD, Rule SA. Time to treatment does not influence overall survival in newly diagnosed mantle-cell lymphoma. J Clin Oncol. 2009;27(32):e189-e190.
    • (2009) J Clin Oncol , vol.27 , Issue.32
    • Eve, H.E.1    Furtado, M.V.2    Hamon, M.D.3    Rule, S.A.4
  • 58
    • 0030907171 scopus 로고    scopus 로고
    • Mantle cell lymphoma: Correlation of clinical outcome and biologic features with three histologic variants
    • Majlis A, Pugh WC, Rodriguez MA, Benedict WF, Cabanillas F. Mantle cell lymphoma: correlation of clinical outcome and biologic features with three histologic variants. J Clin Oncol. 1997;15(4):1664-1671. (Pubitemid 27167407)
    • (1997) Journal of Clinical Oncology , vol.15 , Issue.4 , pp. 1664-1671
    • Majlis, A.1    Pugh, W.C.2    Rodriguez, M.A.3    Benedict, W.F.4    Cabanillas, F.5
  • 63
    • 84857030565 scopus 로고    scopus 로고
    • Behind the scenes of non-nodal MCL: Downmodulation of genes involved in actin cytoskeleton organization, cell projection, cell adhesion, tumour invasion, TP53 pathway and mutated status of immunoglobulin heavy chain genes
    • Del Giudice I, et al. Behind the scenes of non-nodal MCL: downmodulation of genes involved in actin cytoskeleton organization, cell projection, cell adhesion, tumour invasion, TP53 pathway and mutated status of immunoglobulin heavy chain genes. Br J Haematol. 2012;156(5):601-611.
    • (2012) Br J Haematol , vol.156 , Issue.5 , pp. 601-611
    • Del Giudice, I.1
  • 64
    • 84864877555 scopus 로고    scopus 로고
    • Non-nodal type of mantle cell lymphoma is a specific biological and clinical subgroup of the disease
    • Royo C, et al. Non-nodal type of mantle cell lymphoma is a specific biological and clinical subgroup of the disease. Leukemia. 2012;26(8):1895-1898.
    • (2012) Leukemia , vol.26 , Issue.8 , pp. 1895-1898
    • Royo, C.1
  • 65
    • 76749118059 scopus 로고    scopus 로고
    • Genomic and gene expression profiling defines indolent forms of mantle cell lymphoma
    • Fernandez V, et al. Genomic and gene expression profiling defines indolent forms of mantle cell lymphoma. Cancer Res. 2010;70(4):1408-1418.
    • (2010) Cancer Res , vol.70 , Issue.4 , pp. 1408-1418
    • Fernandez, V.1
  • 66
    • 79960547464 scopus 로고    scopus 로고
    • Indolent mantle cell leukemia: Clinicopathologic variant characterized by isolated lymphocytosis, interstitial bone marrow involvement, kappa light chain restriction, and good prognosis
    • Ondrejka SL, Lai R, Kumar N, Smith SD, Hsi ED. Indolent mantle cell leukemia: clinicopathologic variant characterized by isolated lymphocytosis, interstitial bone marrow involvement, kappa light chain restriction, and good prognosis. Haematologica. 2011;96(8):1121-1127.
    • (2011) Haematologica , vol.96 , Issue.8 , pp. 1121-1127
    • Ondrejka, S.L.1    Lai, R.2    Kumar, N.3    Smith, S.D.4    Hsi, E.D.5
  • 67
    • 79957437578 scopus 로고    scopus 로고
    • Indolent mantle-cell lymphoma: Immunoglobulin variable region heavy chain sequence analysis reveals evidence of disease 10 years prior to symptomatic clinical presentation
    • Rule SA, Poplar S, Evans PA, O'Connor SJ, Owen RG. Indolent mantle-cell lymphoma: immunoglobulin variable region heavy chain sequence analysis reveals evidence of disease 10 years prior to symptomatic clinical presentation. J Clin Oncol. 2011;29(15):e437-e439.
    • (2011) J Clin Oncol , vol.29 , Issue.15
    • Rule, S.A.1    Poplar, S.2    Evans, P.A.3    O'Connor, S.J.4    Owen, R.G.5
  • 68
    • 84867513141 scopus 로고    scopus 로고
    • Molecular subsets of mantle cell lymphoma defined by the IGHV mutational status and SOX11 expression have distinct biological and clinical features
    • [published on line ahead of print Aug 20, 2012]. doi:10.1158/0008-5472. CAN-12-1615
    • Navarro A, et al. Molecular subsets of mantle cell lymphoma defined by the IGHV mutational status and SOX11 expression have distinct biological and clinical features [published on line ahead of print Aug 20, 2012]. Cancer Res. doi:10.1158/0008-5472.CAN-12-1615.
    • Cancer Res
    • Navarro, A.1
  • 70
    • 67349217826 scopus 로고    scopus 로고
    • T(11;14)-positive clones can persist over a long period of time in the peripheral blood of healthy individuals
    • Lecluse Y, Lebailly P, Roulland S, Gac AC, Nadel B, Gauduchon P. t(11;14)-positive clones can persist over a long period of time in the peripheral blood of healthy individuals. Leukemia. 2009;23(6):1190-1193.
    • (2009) Leukemia , vol.23 , Issue.6 , pp. 1190-1193
    • Lecluse, Y.1    Lebailly, P.2    Roulland, S.3    Gac, A.C.4    Nadel, B.5    Gauduchon, P.6
  • 71
    • 77957820874 scopus 로고    scopus 로고
    • Mantle cell lymphoma 12 years after allogeneic bone marrow transplantation occurring simultaneously in recipient and donor
    • Christian B, et al. Mantle cell lymphoma 12 years after allogeneic bone marrow transplantation occurring simultaneously in recipient and donor. J Clin Oncol. 2010;28(31):e629-e632.
    • (2010) J Clin Oncol , vol.28 , Issue.31
    • Christian, B.1
  • 72
    • 84856478766 scopus 로고    scopus 로고
    • In situ mantle cell lymphoma: Clinical implications of an incidental finding with indolent clinical behavior
    • Carvajal-Cuenca A, et al. In situ mantle cell lymphoma: clinical implications of an incidental finding with indolent clinical behavior. Haematologica. 2012;97(2):270-278.
    • (2012) Haematologica , vol.97 , Issue.2 , pp. 270-278
    • Carvajal-Cuenca, A.1
  • 73
    • 84867161525 scopus 로고    scopus 로고
    • Evidence of long latency periods prior to development of mantle cell lymphoma
    • Racke F, Simpson S, Christian B, Blum KA, Hasserjian R, Zhao W. Evidence of long latency periods prior to development of mantle cell lymphoma. Blood. 2010;116:2834.
    • (2010) Blood , vol.116 , pp. 2834
    • Racke, F.1    Simpson, S.2    Christian, B.3    Blum, K.A.4    Hasserjian, R.5    Zhao, W.6
  • 74
    • 79952164250 scopus 로고    scopus 로고
    • Should there be a standard therapy for mantle cell lymphoma?
    • Smith MR. Should there be a standard therapy for mantle cell lymphoma? Future Oncol. 2011;7(2):227-237.
    • (2011) Future Oncol , vol.7 , Issue.2 , pp. 227-237
    • Smith, M.R.1
  • 75
    • 79960510971 scopus 로고    scopus 로고
    • Therapy of mantle cell lymphoma: New treatment options in an old disease or vice versa?
    • Dreyling M. Therapy of mantle cell lymphoma: new treatment options in an old disease or vice versa? Semin Hematol. 2011;48(3):145-147.
    • (2011) Semin Hematol , vol.48 , Issue.3 , pp. 145-147
    • Dreyling, M.1
  • 78
    • 84855430944 scopus 로고    scopus 로고
    • Molecular pathways: Targeting proteasomal protein degradation in cancer
    • Molineaux SM. Molecular pathways: targeting proteasomal protein degradation in cancer. Clin Cancer Res. 2012;18(1):15-20.
    • (2012) Clin Cancer Res , vol.18 , Issue.1 , pp. 15-20
    • Molineaux, S.M.1
  • 79
    • 30144442233 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status
    • DOI 10.1182/blood-2005-05-2091
    • Perez-Galan P, Roue G, Villamor N, Montserrat E, Campo E, Colomer D. The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status. Blood. 2006;107(1):257-264. (Pubitemid 43053550)
    • (2006) Blood , vol.107 , Issue.1 , pp. 257-264
    • Perez-Galan, P.1    Roue, G.2    Villamor, N.3    Montserrat, E.4    Campo, E.5    Colomer, D.6
  • 80
    • 78751530756 scopus 로고    scopus 로고
    • Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation
    • Perez-Galan P, et al. Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation. Blood. 2010;117(2):542-552.
    • (2010) Blood , vol.117 , Issue.2 , pp. 542-552
    • Perez-Galan, P.1
  • 81
    • 84861602611 scopus 로고    scopus 로고
    • Proteasome inhibition and combination therapy for non-Hodgkin's lymphoma: From bench to bedside
    • Mato AR, Feldman T, Goy A. Proteasome inhibition and combination therapy for non-Hodgkin's lymphoma: from bench to bedside. Oncologist. 2012;17(5):694-707.
    • (2012) Oncologist , vol.17 , Issue.5 , pp. 694-707
    • Mato, A.R.1    Feldman, T.2    Goy, A.3
  • 82
    • 82555187990 scopus 로고    scopus 로고
    • New molecular targets in mantle cell lymphoma
    • Parekh S, Weniger MA, Wiestner A. New molecular targets in mantle cell lymphoma. Semin Cancer Biol. 2011;21(5):335-346.
    • (2011) Semin Cancer Biol , vol.21 , Issue.5 , pp. 335-346
    • Parekh, S.1    Weniger, M.A.2    Wiestner, A.3
  • 83
    • 33748363502 scopus 로고    scopus 로고
    • The heat shock protein 90 inhibitor 17-AAG induces cell cycle arrest and apoptosis in mantle cell lymphoma cell lines by depleting cyclin D1, Akt, Bid and activating caspase 9
    • DOI 10.1111/j.1365-2141.2006.06247.x
    • Georgakis GV, Li Y, Younes A. The heat shock protein 90 inhibitor 17-AAG induces cell cycle arrest and apoptosis in mantle cell lymphoma cell lines by depleting cyclin D1, Akt, Bid and activating caspase 9. Br J Haematol. 2006;135(1):68-71. (Pubitemid 44337664)
    • (2006) British Journal of Haematology , vol.135 , Issue.1 , pp. 68-71
    • Georgakis, G.V.1    Li, Y.2    Younes, A.3
  • 84
    • 79952773321 scopus 로고    scopus 로고
    • Phase II study of vorinostat for treatment of relapsed or refractory indolent non-Hodgkin's lymphoma and mantle cell lymphoma
    • Kirschbaum M, et al. Phase II study of vorinostat for treatment of relapsed or refractory indolent non-Hodgkin's lymphoma and mantle cell lymphoma. J Clin Oncol. 2011;29(9):1198-1203.
    • (2011) J Clin Oncol , vol.29 , Issue.9 , pp. 1198-1203
    • Kirschbaum, M.1
  • 85
    • 77950516104 scopus 로고    scopus 로고
    • mTOR signaling and drug development in cancer
    • Dancey J. mTOR signaling and drug development in cancer. Nat Rev Clin Oncol. 2010;7(4):209-219.
    • (2010) Nat Rev Clin Oncol , vol.7 , Issue.4 , pp. 209-219
    • Dancey, J.1
  • 86
    • 68949102180 scopus 로고    scopus 로고
    • Phase III study to evaluate temsirolimus compared with investigator's choice therapy for the treatment of relapsed or refractory mantle cell lymphoma
    • Hess J, et al. Phase III study to evaluate temsirolimus compared with investigator's choice therapy for the treatment of relapsed or refractory mantle cell lymphoma. J Clin Oncol. 2009;27(23):3822-3829.
    • (2009) J Clin Oncol , vol.27 , Issue.23 , pp. 3822-3829
    • Hess, J.1
  • 87
    • 49049087320 scopus 로고    scopus 로고
    • Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: A phase 2 trial in the North Central Cancer Treatment Group
    • Ansell SM, et al. Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: a phase 2 trial in the North Central Cancer Treatment Group. Cancer. 2008;113(3):508-514.
    • (2008) Cancer , vol.113 , Issue.3 , pp. 508-514
    • Ansell, S.M.1
  • 88
    • 79953182631 scopus 로고    scopus 로고
    • Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: A phase 2 study
    • Ansell SM, et al. Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: a phase 2 study. Lancet Oncol. 2011;12(4):361-368.
    • (2011) Lancet Oncol , vol.12 , Issue.4 , pp. 361-368
    • Ansell, S.M.1
  • 89
    • 68949102180 scopus 로고    scopus 로고
    • Phase III study to evaluate temsirolimus compared with investigator's choice therapy for the treatment of relapsed or refractory mantle cell lymphoma
    • Hess G, et al. Phase III study to evaluate temsirolimus compared with investigator's choice therapy for the treatment of relapsed or refractory mantle cell lymphoma. J Clin Oncol. 2009;27(23):3822-3829.
    • (2009) J Clin Oncol , vol.27 , Issue.23 , pp. 3822-3829
    • Hess, G.1
  • 90
    • 77953426741 scopus 로고    scopus 로고
    • Temsirolimus for the treatment of mantle cell lymphoma
    • Hess G. Temsirolimus for the treatment of mantle cell lymphoma. Expert Rev Hematol. 2009;2(6):631-640.
    • (2009) Expert Rev Hematol , vol.2 , Issue.6 , pp. 631-640
    • Hess, G.1
  • 92
    • 77956483087 scopus 로고    scopus 로고
    • Cytostatic and anti-angiogenic effects of temsirolimus in refractory mantle cell lymphoma
    • Wang L, et al. Cytostatic and anti-angiogenic effects of temsirolimus in refractory mantle cell lymphoma. J Hematol Oncol. 2010;3:30.
    • (2010) J Hematol Oncol , vol.3 , pp. 30
    • Wang, L.1
  • 93
    • 84863971730 scopus 로고    scopus 로고
    • A multicenter phase II trial (SAKK 36/06) of single-agent Everolimus(RAD001) in patients with relapsed or refractory mantle cell lymphoma
    • Renner C, et al. A multicenter phase II trial (SAKK 36/06) of single-agent Everolimus(RAD001) in patients with relapsed or refractory mantle cell lymphoma. Haematologica. 2012;97(7):1085-1091.
    • (2012) Haematologica , vol.97 , Issue.7 , pp. 1085-1091
    • Renner, C.1
  • 94
    • 51449096670 scopus 로고    scopus 로고
    • A phase 2 clinical trial of deforolimus (AP23573, MK-8669), a novel mammalian target of rapamycin inhibitor, in patients with relapsed or refractory hematologic malignancies
    • Rizzieri DA, et al. A phase 2 clinical trial of deforolimus (AP23573, MK-8669), a novel mammalian target of rapamycin inhibitor, in patients with relapsed or refractory hematologic malignancies. Clin Cancer Res. 2008;14(9):2756-2762.
    • (2008) Clin Cancer Res , vol.14 , Issue.9 , pp. 2756-2762
    • Rizzieri, D.A.1
  • 95
    • 79958784935 scopus 로고    scopus 로고
    • Clinical safety and activity in a phase 1 study of CAL-101, an isoform-selective inhibitor of phosphatidylinositol 3-kinase P110{delta}, in patients with relapsed or refractory non-Hodgkin lymphoma
    • Kahl B, et al. Clinical safety and activity in a phase 1 study of CAL-101, an isoform-selective inhibitor of phosphatidylinositol 3-kinase P110{delta}, in patients with relapsed or refractory non-Hodgkin lymphoma. Blood. 2010;116:1777.
    • (2010) Blood , vol.116 , pp. 1777
    • Kahl, B.1
  • 96
    • 84863393353 scopus 로고    scopus 로고
    • Dual mTORC1/mTORC2 inhibition diminishes Akt activation and induces Puma-dependent apoptosis in lymphoid malignancies
    • Gupta M, et al. Dual mTORC1/mTORC2 inhibition diminishes Akt activation and induces Puma-dependent apoptosis in lymphoid malignancies. Blood. 2012;119(2):476-487.
    • (2012) Blood , vol.119 , Issue.2 , pp. 476-487
    • Gupta, M.1
  • 100
    • 84861210266 scopus 로고    scopus 로고
    • Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma
    • Leonard JP, et al. Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma. Blood. 2012;119(20):4597-4607.
    • (2012) Blood , vol.119 , Issue.20 , pp. 4597-4607
    • Leonard, J.P.1
  • 102
    • 84870921108 scopus 로고    scopus 로고
    • Inhibition of poly(ADP-ribose) polymerase (PARP) and ataxia telangiectasia mutated (ATM) on the chemosensitivity of mantle cell lymphoma to agents that induce DNA strand breaks
    • [published online ahead of print December 14, 2011]. doi:10.1002/hon.1020
    • Golla RM, et al. Inhibition of poly(ADP-ribose) polymerase (PARP) and ataxia telangiectasia mutated (ATM) on the chemosensitivity of mantle cell lymphoma to agents that induce DNA strand breaks [published online ahead of print December 14, 2011]. Hematol Oncol. doi:10.1002/hon.1020.
    • Hematol Oncol
    • Golla, R.M.1
  • 103
    • 78649321855 scopus 로고    scopus 로고
    • The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo
    • Weston VJ, et al. The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo. Blood. 2010;116(22):4578-4587.
    • (2010) Blood , vol.116 , Issue.22 , pp. 4578-4587
    • Weston, V.J.1
  • 104
    • 76649091939 scopus 로고    scopus 로고
    • ATM deficiency sensitizes mantle cell lymphoma cells to poly(ADP-ribose) polymerase-1 inhibitors
    • Williamson CT, et al. ATM deficiency sensitizes mantle cell lymphoma cells to poly(ADP-ribose) polymerase-1 inhibitors. Mol Cancer Ther. 2010;9(2):347-357.
    • (2010) Mol Cancer Ther , vol.9 , Issue.2 , pp. 347-357
    • Williamson, C.T.1
  • 105
    • 60849086456 scopus 로고    scopus 로고
    • Bcl-2 inhibitors: Small molecules with a big impact on cancer therapy
    • Vogler M, Dinsdale D, Dyer MJ, Cohen GM. Bcl-2 inhibitors: small molecules with a big impact on cancer therapy. Cell Death Differ. 2009;16(3):360-367.
    • (2009) Cell Death Differ , vol.16 , Issue.3 , pp. 360-367
    • Vogler, M.1    Dinsdale, D.2    Dyer, M.J.3    Cohen, G.M.4
  • 106
    • 53049106757 scopus 로고    scopus 로고
    • The BH3-only mimetic ABT-737 synergizes the antineoplastic activity of proteasome inhibitors in lymphoid malignancies
    • Paoluzzi L, et al. The BH3-only mimetic ABT-737 synergizes the antineoplastic activity of proteasome inhibitors in lymphoid malignancies. Blood. 2008;112(7):2906-2916.
    • (2008) Blood , vol.112 , Issue.7 , pp. 2906-2916
    • Paoluzzi, L.1
  • 107
    • 34248362003 scopus 로고    scopus 로고
    • The BH3-mimetic GX15-070 synergizes with bortezomib in mantle cell lymphoma by enhancing Noxa-mediated activation of Bak
    • DOI 10.1182/blood-2006-07-034173
    • Perez-Galan P, Roue G, Villamor N, Campo E, Colomer D. The BH3-mimetic GX15-070 synergizes with bortezomib in mantle cell lymphoma by enhancing Noxa-mediated activation of Bak. Blood. 2007;109(10):4441-4449. (Pubitemid 46743414)
    • (2007) Blood , vol.109 , Issue.10 , pp. 4441-4449
    • Perez-Galan, P.1    Roue, G.2    Villamor, N.3    Campo, E.4    Colomer, D.5
  • 109
    • 78649630259 scopus 로고    scopus 로고
    • Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: A phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity
    • Wilson WH, et al. Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity. Lancet Oncol. 2010;11(12):1149-1159.
    • (2010) Lancet Oncol , vol.11 , Issue.12 , pp. 1149-1159
    • Wilson, W.H.1
  • 110
    • 79960366781 scopus 로고    scopus 로고
    • Enzastaurin hydrochloride for lymphoma: Reassessing the results of clinical trials in light of recent advances in the biology of B-cell malignancies
    • Ysebaert L, Morschhauser F. Enzastaurin hydrochloride for lymphoma: reassessing the results of clinical trials in light of recent advances in the biology of B-cell malignancies. Expert Opin Investig Drugs. 2011;20(8):1167- 1174.
    • (2011) Expert Opin Investig Drugs , vol.20 , Issue.8 , pp. 1167-1174
    • Ysebaert, L.1    Morschhauser, F.2
  • 111
    • 77951002653 scopus 로고    scopus 로고
    • Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia
    • Friedberg JW, et al. Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia. Blood. 2010;115(13):2578-2585.
    • (2010) Blood , vol.115 , Issue.13 , pp. 2578-2585
    • Friedberg, J.W.1
  • 112
    • 84860430028 scopus 로고    scopus 로고
    • The Bruton's tyrosine kinase inhibitor PCI-32765 is highly active as single-agent therapy in previously-treated Mantle Cell Lymphoma (MCL): Preliminary results of a phase II trial
    • Wang L, et al. The Bruton's tyrosine kinase inhibitor PCI-32765 is highly active as single-agent therapy in previously-treated Mantle Cell Lymphoma (MCL): preliminary results of a phase II trial. Blood. 2011;118:442.
    • (2011) Blood , vol.118 , pp. 442
    • Wang, L.1
  • 113
    • 79960195896 scopus 로고    scopus 로고
    • Phase i study of a novel oral JAK-2 inhibitor SB1518 in patients with relapsed lymphoma: Evidence of clinical and biologic activity in multiple lymphoma subtypes
    • Younes A, Fanale MA, McLaughlin P, Copeland A, Zhu J, de Castro Faria S. Phase I study of a novel oral JAK-2 inhibitor SB1518 in patients with relapsed lymphoma: evidence of clinical and biologic activity in multiple lymphoma subtypes. Blood. 2010;116:2830.
    • (2010) Blood , vol.116 , pp. 2830
    • Younes, A.1    Fanale, M.A.2    McLaughlin, P.3    Copeland, A.4    Zhu, J.5    De Castro Faria, S.6
  • 114
    • 78649466892 scopus 로고    scopus 로고
    • Targeting Notch signaling pathway to overcome drug resistance for cancer therapy
    • Wang Z, et al. Targeting Notch signaling pathway to overcome drug resistance for cancer therapy. Biochim Biophys Acta. 2010;1806(2):258-267.
    • (2010) Biochim Biophys Acta , vol.1806 , Issue.2 , pp. 258-267
    • Wang, Z.1
  • 115
    • 74049145806 scopus 로고    scopus 로고
    • Therapeutic targeting of NOTCH1 signaling in T-cell acute lymphoblastic leukemia
    • Palomero T, Ferrando A. Therapeutic targeting of NOTCH1 signaling in T-cell acute lymphoblastic leukemia. Clin Lymphoma Myeloma. 2009;9(suppl 3):S205-S210.
    • (2009) Clin Lymphoma Myeloma , vol.9 , Issue.SUPPL. 3
    • Palomero, T.1    Ferrando, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.