The regulatory mechanism of the caspase 6 pro-domain revealed by crystal structure and biochemical assays

Acta Crystallographica Section D: Biological Crystallography

Volumn 70, Issue 1, 2014, Pages 58-67

  Cao, Qin ^a   Wang, Xiao Jun ^a   Li, Lan Fen ^a   Su, Xiao Dong ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

activation; caspase 6; full length zymogen; neurodegenerative diseases; pro domain

Indexed keywords

CASPASE 6;

ACTIVATION; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DEGENERATIVE DISEASE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYMOLOGY; FULL-LENGTH ZYMOGEN; GENETICS; HUMAN; METABOLISM; MUTATION; PRO-DOMAIN; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ACTIVATION; CASPASE 6; FULL-LENGTH ZYMOGEN; NEURODEGENERATIVE DISEASES; PRO-DOMAIN;

CASPASE 6; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; HUMANS; MODELS, MOLECULAR; MUTATION; NEURODEGENERATIVE DISEASES; PROTEIN STRUCTURE, TERTIARY;

EID: 84892383815     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S1399004713024218     Document Type: Article

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