Crystal structures of human caspase 6 reveal a new mechanism for intramolecular cleavage self-activation

EMBO Reports

Volumn 11, Issue 11, 2010, Pages 841-847

  Wang, Xiao Jun ^a   Cao, Qin ^a   Liu, Xiang ^a   Wang, Kai Tuo ^a   Mi, Wei ^a   Zhang, Yan ^b   Li, Lan Fen ^a   Leblanc, Andrea C ^c   Su, Xiao Dong ^a,b  

^a National Laboratory of Protein Engineering and Plant Genetic Engineering   (China)

^b PEKING UNIVERSITY   (China)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Alzheimer disease; apoptosis; caspase 6; cysteine protease; intramolecular cleavage

Indexed keywords

CASPASE 6;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME STRUCTURE; HUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; CASPASE 6; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY;

EID: 78049347657     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2010.141     Document Type: Article

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