ADAM17-mediated processing of TNF-α expressed by antiviral effector CD8+ T cells is required for severe T-cell-mediated lung injury

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  DeBerge, Matthew P ^a   Ely, Kenneth H ^a   Cheng, Guang Shing ^b   Enelow, Richard I ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; CHEMOKINE RECEPTOR CXCR2; CXCL2 CHEMOKINE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; EPITHELIUM CELL; FEMALE; INFLAMMATORY CELL; INFLUENZA A; INHIBITION KINETICS; LUNG ALVEOLUS; LUNG ALVEOLUS EPITHELIUM; LUNG INJURY; LYMPHOCYTE TRANSFER; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PROCESSING; SURVIVAL RATE; T LYMPHOCYTE;

ADAM PROTEINS; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; LUNG; LUNG INJURY; MACROPHAGES; MICE; NEUTROPHIL INFILTRATION; PROTEOLYSIS; RECEPTORS, INTERLEUKIN-8B; SIGNAL TRANSDUCTION; SOLUBILITY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84892383222     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079340     Document Type: Article

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