Structural and functional consequences of alveolar cell recognition by CD8+ T lymphocytes in experimental lung disease

Journal of Clinical Investigation

Volumn 102, Issue 9, 1998, Pages 1653-1661

  Enelow, Richard I ^a,b   Mohammed, Ashraf Z ^a   Stoler, Mark H ^a   Liu, Angela Ning ^a   Young, Jeffrey S ^a   Lou, Ya Huan ^a   Braciale, Thomas J ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

Alveolar cell; Diffusion; Interstitial pneumonia; Lung injury; T lymphocyte

Indexed keywords

AUTOANTIGEN; VIRUS HEMAGGLUTININ;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; INTERSTITIAL PNEUMONIA; LUNG ALVEOLUS CELL; LUNG GAS EXCHANGE; LUNG INJURY; LUNG MECHANICS; LYMPHOCYTIC INFILTRATION; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TACHYPNEA; TRANSGENIC MOUSE; WEIGHT REDUCTION;

EID: 0032211841     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI4174     Document Type: Article

References (42)

1. Costabel, U., H. Teschler, and J. Guzman. 1992. Bronchiolitis obliterans organizing pneumonia (BOOP): the cytological and immunocytological profile of bronchoalveolar lavage. Eur. Respir. J. 5:791-797.
2. Katzenstein, A. 1997. Katzenstein and Askin's Surgical Pathology of Non-neoplastic Lung Disease. WB Saunders, Philadelphia.
3. Kradin, R.L., M.B. Divertie, R.B. Colvin, J. Ramirez, J. Ryu, H.A. Carpenter, and A.K. Bhan. 1986. Usual interstitial pneumonitis is a T-cell alveolitis. Clin. Immunol. Immunopathol. 40:224-235.
4. Leatherman, J., A. Michael, B. Schwartz, and J. Hoidal. 1984. Lung T cells in hypersensitivity pneumonitis. Ann. Intern. Med. 100:390-396.
5. Lukacher, A.E., L.A. Morrison, V.L. Braciale, and T.J. Braciale. 1986. T lymphocyte function in recovery from experimental viral infection: the influenza model. In Mechanisms of Host Resistance to Infectious Agents, Tumors, and Allografts. R.M. Steinman, editor. The Rockefeller University Press. New York. 233-254.
6. Kagi, D., F. Vignaux, B. Ledermann, K. Burki, V. Depraetere, S. Nagata, H. Nengartner, and P. Golstein. 1994. Fas and perforin as major mechanisms of T cell-mediated cytotoxicity. Science. 265:528-530.
7. Kojima, H., N. Shinohara, S. Hanaoka, S.Y. Someya, Y. Takagaki, H. Ohno, T. Saito, T. Katayama, H. Yagita, K. Okumura, et al. 1994. Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes. Immunity. 1:357-364.
8. Walsh, C., M. Matloubian, C. Lui, R. Udea, C. Kurahara, J. Christiansen, M. Huang, J. Young, R. Ahmed, and W. Clark. 1994. Immune function in mice lacking the perforin gene. Proc. Natl. Acad. Sci. USA. 91:10854-10858.
9. Walsh, C.M., A.A. Glass, V. Chiu, and W.R. Clark. 1994. The role of the Fas lytic pathway in a perforin-less CTL hybridoma. J. Immunol. 153:2506-2514.
10. Lukacher, A.E., V.L. Braciale, and T.J. Braciale. 1984. In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific. J. Exp. Med. 160:814-826.
11. Ada, G., and P. Jones. 1986. The immune responses to influenza infection. Curr. Topics Microbiol. Immunol. 128:1-54.
12. Wells, M.A., P. Albrecht, and F.A. Ennis. 1981. Recovery from a viral respiratory infection: I. Influenza pneumonia in normal and T-deficient mice. J. Immunol. 126:1036-1041.
13. Scherle, P.A., G. Palladino, and W. Gerhard. 1992. Mice can recover from pulmonary influenza virus infection in the absence of class I-restricted cytotoxic T cells. J. Immunol. 148:212-217.
14. Spurzem, J., and S. Rennard. 1996. Immunology of idiopathic pulmonary fibrosis. In Immunopathology of Lung Disease. R. Kradin and B. Robinson, editors. Butterworth-Heinemann, Boston. 119-131.
15. Crystal, R.G., J.D. Fulmer, W.C. Roberts, M.L. Moss, B.R. Line, and H.Y. Reynolds. 1976. Idiopathic pulmonary fibrosis. Clinical, histologic, radiographic, physiologic, scintigraphic, cytologic, and biochemical aspects. Ann. Intern. Med. 85:769-788.
16. Shanley, T.P., H. Schmal, H.P. Friedl, M.L. Jones, and P.A. Ward. 1995. Role of macrophage inflammatory protein-1 alpha (MIP-1 alpha) in acute lung injury in rats. J. Immunol. 154:4793-4802.
17. Leturcq, D.J., A.M. Moriarty, G. Talbott, R.K. Winn, T.R. Martin, and R.J. Ulevitch. 1996. Antibodies against CD14 protect primates from endotoxin-induced shock. J. Clin. Invest. 98:1533-1538.
18. Doherty, D.E., G.P. Downey, B. Schwab III, E. Elson, and G.S. Worthen. 1994. Lipopolysaccharide-induced monocyte retention in the lung. Role of monocyte stiffness, actin assembly, and CD18-dependent adherence. J. Immunol. 153:241-255.
19. Schrier, D., S. Phan, and P. Ward. 1982. Cellular sensitivity to collagen in bleomycin-treated rats. J. Immunol. 129:2156-2159.
20. Snider, G., J. Hayes, and A. Korthy. 1978. Chronic interstitial pulmonary fibrosis produced in hamsters by endotracheal bleomycin. Am. Rev. Respir. Dis. 177:1099-1108.
21. Bowden, D.H. 1984. Unraveling pulmonary fibrosis: the bleomycin model. Lab. Invest. 50:487-488.
22. Openshaw, P.J. 1995. Immunity and immunopathology to respiratory syncytial virus. The mouse model. Am. J. Respir. Crit. Care Med. 152:559-562.
23. Alwan, W.H., W.J. Kozlowska, and P.J. Openshaw. 1994. Distinct types of lung disease caused by functional subsets of antiviral T cells. J. Exp. Med. 179:81-89.
24. + T helper type 2 T lymphocytes do not promote recovery from experimental virus infection. J. Exp. Med. 180:1273-1282.
25. + T lymphocytes. J. Lenk. Biol. 54:414-422.
26. + T cell reactivity. J. Clin. Invest. 98: 914-922.
27. Graham, M., T. Braciale, and V. Braciale. 1996. Use of antiviral T-lymphocyte clones to characterize antigen presentation and T-lymphocyte subsets. Methods: A Companion to Meth. Enzymol. 9:439-444.
28. Bergmann, K., B. Lachmann, and K. Noack. 1984. Lung mechanics in orally immunized mice after aerolized exposure to influenza virus. Respiration. 46:218-221.
29. Hartsfield, C., D. Lipke, Y. Lai, D. Cohen, and M. Gillespie. 1997. Pulmonary mechanical and immunologic dysfunction in a murine model of AIDS. Am. J. Physiol. 272:L699-L706.
30. Takezawa, J., F. Miller, and J. O'Neil. 1980. Single-breath diffusing capacity and lung volumes in small laboratory mammals. J. Appl. Physiol: Respir. Environ. Exercise Physiol. 48:1052-1059.
31. Sabo, J., E. Kimmel, and L. Diamond. 1983. Effects of the clara cell toxin, 4-ipomeanol, on pulmonary function in rats. J. Appl. Physiol. 54:337-344.
32. Depledge, M., C. Collis, and A. Barrett. 1981. A technique for measuring carbon monoxide uptake in mice. Int. J. Rad. One. Biol. Physics. 7:485-489.
33. + T cells by a self-derived peptide. Nature. 378:295-298.
34. Fulcher, D.A., A.B. Lyons, S.L. Korn, M.C. Cook, C. Koleda, C. Parish, B. Fazekas de St. Groth, and A. Basten. 1996. The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help. J. Exp. Med. 183:2313-2328.
35. Lyons, A.B., and C.R. Parish. 1994. Determination of lymphocyte division by flow cytometry. J. Immunol. Methods. 171:131-137.
36. Curtis, J., M. Warnock, S. Arraj, and H. Kaltreider. 1990. Histologic analysis of an immune response in the lung parenchyma of mice. Am. J. Pathol. 137:689-699.
37. Stein-Streilein, J., M.F. Lipscomb, D.A. Hart, and A. Darden. 1981. Graft-versus-host reaction in the lung. Transplantation. 32:38-44.
38. Hempleman, S.C, and J.M. Hughes. 1991. Estimating exercise DLO2 and diffusion limitation in patients with interstitial fibrosis (published erratum 1991, 85:137). Respir. Physiol. 83:167-178.
39. Agusta, A., J. Roca, J. Gea, P. Wagner, X. Xaubet, and R. Rodriguez-Rosen. 1991. Mechanisms of gas exchange impairment in idiopathic pulmonary fibrosis. Am. Rev. Respir. Dis. 143:219-225.
40. Eklund, A., L. Broman, M. Broman, and A. Holmgren. 1989. V/Q and alveolar gas exchange in pulmonary sarcoidosis. Eur. Respir. J. 2:135-144.
41. Ryan, S., C. Barrett, M. Lavietes, A. Bell, and D. Rochester. 1978. Volume-pressure and morphometric observations after acute alveolar injury in the dog from N-nitroso-N-methylurethane. Am. Rev. Respir. Dis. 118:735-745.
42. Epler, G. 1991. Bronchiolitis obliterans. In Immunologically Mediated Pulmonary Diseases. J. Lynch and R. DeRemee, editors. Lippincott, Philadelphia. 156-168.