-
1
-
-
84859847164
-
Emerging insights into the molecular and cellular basis of glioblastoma
-
Dunn GP, Rinne ML, Wykosky J, et al. Emerging insights into the molecular and cellular basis of glioblastoma. Genes Develop 2012; 26:756-784.
-
(2012)
Genes Develop
, vol.26
, pp. 756-784
-
-
Dunn, G.P.1
Rinne, M.L.2
Wykosky, J.3
-
2
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons DW, Jones S, Zhang X, et al. An integrated genomic analysis of human glioblastoma multiforme. Science 2008; 321:1807-1812.
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
-
3
-
-
79251601011
-
A sensitive and specific diagnostic panel to distinguish diffuse astrocytoma from astrocytosis: Chromosome 7 gain with mutant isocitrate dehydrogenase 1 and p53
-
Camelo-Piragua S, Jansen M, Ganguly A, et al. A sensitive and specific diagnostic panel to distinguish diffuse astrocytoma from astrocytosis: Chromosome 7 gain with mutant isocitrate dehydrogenase 1 and p53. J Neuropathol Exp Neurol 2011; 70:110-115.
-
(2011)
J Neuropathol Exp Neurol
, vol.70
, pp. 110-115
-
-
Camelo-Piragua, S.1
Jansen, M.2
Ganguly, A.3
-
4
-
-
84864050066
-
IDH mutations as an early and consistent marker in low-grade astrocytomas WHO grade 2 and their consecutive secondary high-grade gliomas
-
Juratli TA, Kirsch M, Robel K, et al. IDH mutations as an early and consistent marker in low-grade astrocytomas WHO grade 2 and their consecutive secondary high-grade gliomas. J Neuro-oncol 2012; 108:403-410.
-
(2012)
J Neuro-oncol
, vol.108
, pp. 403-410
-
-
Juratli, T.A.1
Kirsch, M.2
Robel, K.3
-
5
-
-
84868625787
-
Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
-
Jiao Y, Killela PJ, Reitman ZJ, et al. Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas. Oncotarget 2012; 3:709-722.
-
(2012)
Oncotarget
, vol.3
, pp. 709-722
-
-
Jiao, Y.1
Killela, P.J.2
Reitman, Z.J.3
-
6
-
-
84872788316
-
Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma
-
Kannan K, Inagaki A, Silber J, et al. Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma. Oncotarget 2012; 3:1194-1203.
-
(2012)
Oncotarget
, vol.3
, pp. 1194-1203
-
-
Kannan, K.1
Inagaki, A.2
Silber, J.3
-
7
-
-
84871020024
-
Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations
-
Liu XY, Gerges N, Korshunov A, et al. Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations. Acta Neuropathol 2012; 124:615-625.
-
(2012)
Acta Neuropathol
, vol.124
, pp. 615-625
-
-
Liu, X.Y.1
Gerges, N.2
Korshunov, A.3
-
8
-
-
84887123502
-
The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: A multiinstitutional study of 214 astrocytomas
-
[Epub ahead of print]
-
Abedalthagafi M, Phillips JJ, Kim GE, et al. The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: A multiinstitutional study of 214 astrocytomas. Mod Pathol 2013. [Epub ahead of print]
-
(2013)
Mod Pathol
-
-
Abedalthagafi, M.1
Phillips, J.J.2
Kim, G.E.3
-
9
-
-
84886712846
-
Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas
-
Fontebasso AM, Schwartzentruber J, Khuong-Quang DA, et al. Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas. Acta Neuropathol 2013; 125:659-669.
-
(2013)
Acta Neuropathol
, vol.125
, pp. 659-669
-
-
Fontebasso, A.M.1
Schwartzentruber, J.2
Khuong-Quang, D.A.3
-
10
-
-
84879475201
-
BRAF V600E mutation identifies a subset of low-grade diffusely infiltrating gliomas in adults
-
Chi AS, Batchelor TT, Yang D, et al. BRAF V600E mutation identifies a subset of low-grade diffusely infiltrating gliomas in adults. J Clin Oncol 2013; 31:e233-e236.
-
(2013)
J Clin Oncol
, vol.31
-
-
Chi, A.S.1
Batchelor, T.T.2
Yang, D.3
-
11
-
-
80052608062
-
Mutations in CIC and FUBP1 contribute to human oligodendroglioma
-
Bettegowda C, Agrawal N, Jiao Y, et al. Mutations in CIC and FUBP1 contribute to human oligodendroglioma. Science 2011; 333:1453-1455.
-
(2011)
Science
, vol.333
, pp. 1453-1455
-
-
Bettegowda, C.1
Agrawal, N.2
Jiao, Y.3
-
12
-
-
82755194965
-
Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers
-
Yip S, Butterfield YS, Morozova O, et al. Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers. J Pathol 2012; 226:7-16.
-
(2012)
J Pathol
, vol.226
, pp. 7-16
-
-
Yip, S.1
Butterfield, Y.S.2
Morozova, O.3
-
13
-
-
84876067164
-
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
-
Killela PJ, Reitman ZJ, Jiao Y, et al. TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Proc Natl Acad Sci U S A 2013; 110:6021-6026.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 6021-6026
-
-
Killela, P.J.1
Reitman, Z.J.2
Jiao, Y.3
-
14
-
-
84867574186
-
KIAA1549-BRAF fusions and IDH mutations can coexist in diffuse gliomas of adults
-
Badiali M, Gleize V, Paris S, et al. KIAA1549-BRAF fusions and IDH mutations can coexist in diffuse gliomas of adults. Brain Pathol 2012; 22:841-847.
-
(2012)
Brain Pathol
, vol.22
, pp. 841-847
-
-
Badiali, M.1
Gleize, V.2
Paris, S.3
-
15
-
-
84867574820
-
Frequent BRAF gain in low-grade diffuse gliomas with 1p/19q loss
-
Kim YH, Nonoguchi N, Paulus W, et al. Frequent BRAF gain in low-grade diffuse gliomas with 1p/19q loss. Brain Pathol 2012; 22:834-840.
-
(2012)
Brain Pathol
, vol.22
, pp. 834-840
-
-
Kim, Y.H.1
Nonoguchi, N.2
Paulus, W.3
-
16
-
-
83455176258
-
Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma
-
Snuderl M, Fazlollahi L, Le LP, et al. Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma. Cancer Cell 2011; 20:810-817.
-
(2011)
Cancer Cell
, vol.20
, pp. 810-817
-
-
Snuderl, M.1
Fazlollahi, L.2
Le, L.P.3
-
17
-
-
84873347374
-
The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma
-
Parker BC, Annala MJ, Cogdell DE, et al. The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma. J Clin Invest 2013; 123:855-865.
-
(2013)
J Clin Invest
, vol.123
, pp. 855-865
-
-
Parker, B.C.1
Annala, M.J.2
Cogdell, D.E.3
-
18
-
-
84865805666
-
Transforming fusions of FGFR and TACC genes in human glioblastoma
-
Singh D, Chan JM, Zoppoli P, et al. Transforming fusions of FGFR and TACC genes in human glioblastoma. Science 2012; 337:1231-1235.
-
(2012)
Science
, vol.337
, pp. 1231-1235
-
-
Singh, D.1
Chan, J.M.2
Zoppoli, P.3
-
19
-
-
84878543522
-
An aberrant transcription factor network essential for wnt signaling and stem cell maintenance in glioblastoma
-
Rheinbay E, Suva ML, Gillespie SM, et al. An aberrant transcription factor network essential for wnt signaling and stem cell maintenance in glioblastoma. Cell Rep 2013; 3:1567-1579.
-
(2013)
Cell Rep
, vol.3
, pp. 1567-1579
-
-
Rheinbay, E.1
Suva, M.L.2
Gillespie, S.M.3
-
20
-
-
84874645357
-
Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant wnt activation
-
Morris LG, Kaufman AM, Gong Y, et al. Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant wnt activation. Nat Genet 2013; 45:253-261.
-
(2013)
Nat Genet
, vol.45
, pp. 253-261
-
-
Morris, L.G.1
Kaufman, A.M.2
Gong, Y.3
-
21
-
-
84878723078
-
Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas
-
St. Jude Children's Research Hospital- Washington University Pediatric Cancer Genome Project
-
Zhang J, Wu G, Miller CP, et al., St. Jude Children's Research Hospital- Washington University Pediatric Cancer Genome Project. Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nat Genet 2013; 45:602-612.
-
(2013)
Nat Genet
, vol.45
, pp. 602-612
-
-
Zhang, J.1
Wu, G.2
Miller, C.P.3
-
22
-
-
84862777348
-
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
-
Schwartzentruber J, Korshunov A, Liu XY, et al. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 2012; 482:226-231.
-
(2012)
Nature
, vol.482
, pp. 226-231
-
-
Schwartzentruber, J.1
Korshunov, A.2
Liu, X.Y.3
-
23
-
-
84862777410
-
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and nonbrainstem glioblastomas
-
Wu G, Broniscer A, McEachron TA, et al. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and nonbrainstem glioblastomas. Nat Genet 2012; 44:251-253.
-
(2012)
Nat Genet
, vol.44
, pp. 251-253
-
-
Wu, G.1
Broniscer, A.2
McEachron, T.A.3
-
24
-
-
84867606428
-
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma
-
Sturm D, Witt H, Hovestadt V, et al. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell 2012; 22:425-437.
-
(2012)
Cancer Cell
, vol.22
, pp. 425-437
-
-
Sturm, D.1
Witt, H.2
Hovestadt, V.3
-
25
-
-
84877785024
-
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma
-
Lewis PW, Muller MM, Koletsky MS, et al. Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Science 2013; 340:857-861.
-
(2013)
Science
, vol.340
, pp. 857-861
-
-
Lewis, P.W.1
Muller, M.M.2
Koletsky, M.S.3
-
26
-
-
84882273357
-
Evaluation of histone 3 lysine trimethylation (H3K27me3) and enhancer of zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas
-
Venneti S, Garimella MT, Sullivan LM, et al. Evaluation of histone 3 lysine trimethylation (H3K27me3) and enhancer of zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas. Brain Pathol 2013; 23:558-564.
-
(2013)
Brain Pathol
, vol.23
, pp. 558-564
-
-
Venneti, S.1
Garimella, M.T.2
Sullivan, L.M.3
-
27
-
-
84877621282
-
Histone H3.3 mutations drive pediatric glioblastoma through upregulation of MYCN
-
[Epub ahead of print]
-
Bjerke L, Mackay A, Nandhabalan M, et al. Histone H3.3 mutations drive pediatric glioblastoma through upregulation of MYCN. Cancer Discov 2013. [Epub ahead of print]
-
(2013)
Cancer Discov
-
-
Bjerke, L.1
Mackay, A.2
Nandhabalan, M.3
-
28
-
-
84863393028
-
Molecular subgroups of medulloblastoma: An international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, group 3, and group 4 medulloblastomas
-
Kool M, Korshunov A, Remke M, et al. Molecular subgroups of medulloblastoma: An international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, group 3, and group 4 medulloblastomas. Acta Neuropathol 2012; 123:473-484.
-
(2012)
Acta Neuropathol
, vol.123
, pp. 473-484
-
-
Kool, M.1
Korshunov, A.2
Remke, M.3
-
29
-
-
84870215426
-
Medulloblastomics: The end of the beginning
-
Northcott PA, Jones DT, Kool M, et al. Medulloblastomics: The end of the beginning. Nat Rev Cancer 2012; 12:818-834.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 818-834
-
-
Northcott, P.A.1
Jones, D.T.2
Kool, M.3
-
30
-
-
84862688169
-
Subgroup-specific alternative splicing in medulloblastoma
-
Dubuc AM, Morrissy AS, Kloosterhof NK, et al. Subgroup-specific alternative splicing in medulloblastoma. Acta Neuropathol 2012; 123: 485-499.
-
(2012)
Acta Neuropathol
, vol.123
, pp. 485-499
-
-
Dubuc, A.M.1
Morrissy, A.S.2
Kloosterhof, N.K.3
-
31
-
-
84864419974
-
Dissecting the genomic complexity underlying medulloblastoma
-
Jones DT, Jager N, Kool M, et al. Dissecting the genomic complexity underlying medulloblastoma. Nature 2012; 488:100-105.
-
(2012)
Nature
, vol.488
, pp. 100-105
-
-
Jones, D.T.1
Jager, N.2
Kool, M.3
-
32
-
-
84864492215
-
Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations
-
Pugh TJ, Weeraratne SD, Archer TC, et al. Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. Nature 2012; 488:106-110.
-
(2012)
Nature
, vol.488
, pp. 106-110
-
-
Pugh, T.J.1
Weeraratne, S.D.2
Archer, T.C.3
-
33
-
-
84864444165
-
Novel mutations target distinct subgroups of medulloblastoma
-
Robinson G, Parker M, Kranenburg TA, et al. Novel mutations target distinct subgroups of medulloblastoma. Nature 2012; 488:43-48.
-
(2012)
Nature
, vol.488
, pp. 43-48
-
-
Robinson, G.1
Parker, M.2
Kranenburg, T.A.3
-
34
-
-
84878857067
-
Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma
-
Dubuc AM, Remke M, Korshunov A, et al. Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma. Acta Neuropathol 2013; 125:373-384.
-
(2013)
Acta Neuropathol
, vol.125
, pp. 373-384
-
-
Dubuc, A.M.1
Remke, M.2
Korshunov, A.3
-
35
-
-
79954444747
-
Medulloblastoma: Clinicopathological correlates of SHH, WNT and non-SHH/WNT molecular subgroups
-
Ellison DW, Dalton J, Kocak M, et al. Medulloblastoma: Clinicopathological correlates of SHH, WNT and non-SHH/WNT molecular subgroups. Acta Neuropathol 2011; 121:381-396.
-
(2011)
Acta Neuropathol
, vol.121
, pp. 381-396
-
-
Ellison, D.W.1
Dalton, J.2
Kocak, M.3
-
36
-
-
84874645692
-
Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations
-
Brastianos PK, Horowitz PM, Santagata S, et al. Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations. Nat Genet 2013; 45:285-289.
-
(2013)
Nat Genet
, vol.45
, pp. 285-289
-
-
Brastianos, P.K.1
Horowitz, P.M.2
Santagata, S.3
-
37
-
-
84874372046
-
Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1 and SMO
-
Clark VE, Erson-Omay EZ, Serin A, et al. Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1 and SMO. Science 2013; 339:1077-1080.
-
(2013)
Science
, vol.339
, pp. 1077-1080
-
-
Clark, V.E.1
Erson-Omay, E.Z.2
Serin, A.3
-
38
-
-
84878864987
-
Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations
-
Reuss DE, Piro RM, Jones DT, et al. Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations. Acta Neuropathol 2013; 125:351-358.
-
(2013)
Acta Neuropathol
, vol.125
, pp. 351-358
-
-
Reuss, D.E.1
Piro, R.M.2
Jones, D.T.3
-
39
-
-
84866100107
-
Loss of SUFU function in familial multiple meningioma
-
Aavikko M, Li SP, Saarinen S, et al. Loss of SUFU function in familial multiple meningioma. Am J Hum Genet 2012; 91:520-526.
-
(2012)
Am J Hum Genet
, vol.91
, pp. 520-526
-
-
Aavikko, M.1
Li, S.P.2
Saarinen, S.3
-
40
-
-
84874657913
-
Loss-of-function mutations in SMARCE1 cause an inherited disorder of multiple spinal meningiomas
-
Smith MJ, O'Sullivan J, Bhaskar SS, et al. Loss-of-function mutations in SMARCE1 cause an inherited disorder of multiple spinal meningiomas. Nat Genet 2013; 45:295-298.
-
(2013)
Nat Genet
, vol.45
, pp. 295-298
-
-
Smith, M.J.1
O'Sullivan, J.2
Bhaskar, S.S.3
-
41
-
-
84875537133
-
Epigenetic reprogramming in cancer
-
Suva ML, Riggi N, Bernstein BE. Epigenetic reprogramming in cancer. Science 2013; 339:1567-1570.
-
(2013)
Science
, vol.339
, pp. 1567-1570
-
-
Suva, M.L.1
Riggi, N.2
Bernstein, B.E.3
-
42
-
-
84878362165
-
The next step in brain tumor classification: Let us now praise famous men' or molecules?
-
Louis DN. The next step in brain tumor classification: 'Let us now praise famous men' Or molecules? Acta Neuropathol 2012; 124:761-762.
-
(2012)
Acta Neuropathol
, vol.124
, pp. 761-762
-
-
Louis, D.N.1
|