Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations

Nature Genetics

Volumn 45, Issue 3, 2013, Pages 285-289

  Brastianos, Priscilla K ^a,b,c,d   Horowitz, Peleg M ^a,c,d,e   Santagata, Sandro ^c,e   Jones, Robert T ^a   Mckenna, Aaron ^d   Getz, Gad ^d   Ligon, Keith L ^c,e   Palescandolo, Emanuele ^a   Van Hummelen, Paul ^a   Ducar, Matthew D ^a   Raza, Alina ^a   Sunkavalli, Ashwini ^a   Macconaill, Laura E ^a   Stemmer Rachamimov, Anat O ^b,c   Louis, David N ^b,c   Hahn, William C ^a,c,d   Dunn, Ian F ^c,d,e   Beroukhim, Rameen ^a,c,d  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; LEUCINE; LYSINE; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN PATCHED 1; SMOOTHENED PROTEIN; TRYPTOPHAN;

AMINO ACID SUBSTITUTION; ARTICLE; CANCER GRADING; CANCER SUSCEPTIBILITY; CHROMOSOME 10Q; CHROMOSOME 14Q; CHROMOSOME REARRANGEMENT; COPY NUMBER VARIATION; EPIGENETICS; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; HUMAN; MEDULLOBLASTOMA; MENINGIOMA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SKULL BASE TUMOR;

BASE SEQUENCE; BRAIN NEOPLASMS; GENOMICS; HUMANS; MENINGIOMA; MUTATION; NEUROFIBROMIN 2; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84874645692     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2526     Document Type: Article

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