Identification of a Major Determinant for Serine-Threonine Kinase Phosphoacceptor Specificity

Molecular Cell

Volumn 53, Issue 1, 2014, Pages 140-147

  Chen, Catherine ^a   Ha, Byung Hak ^a   Thévenin, Anastasia F ^a   Lou, Hua Jane ^a   Zhang, Rong ^a   Yip, Kevin Y ^b,c   Peterson, Jeffrey R ^d   Gerstein, Mark ^b   Kim, Philip M ^e   Filippakopoulos, Panagis ^f,g   Knapp, Stefan ^f   Boggon, Titus J ^a   Turk, Benjamin E ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^d FOX CHASE CANCER CENTER   (United States)

^e UNIVERSITY OF TORONTO   (Canada)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

P21 ACTIVATED KINASE 4; PROTEIN KINASE C; PROTEIN SERINE THREONINE KINASE; MST4 PROTEIN, HUMAN; P21 ACTIVATED KINASE; PAK4 PROTEIN, HUMAN; PEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CELL STRAIN HEK293; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MUTAGENESIS; PROTEIN CONFORMATION; PROTEIN PHOSPHORYLATION; STEREOSPECIFICITY; X RAY CRYSTALLOGRAPHY; BINDING SITE; CHEMISTRY; GENETICS; HEK293 CELL LINE; KINETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

EUKARYOTA;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HEK293 CELLS; HUMANS; KINETICS; P21-ACTIVATED KINASES; PEPTIDES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SUBSTRATE SPECIFICITY;

EID: 84892364761     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2013.11.013     Document Type: Article

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