Structural basis and prediction of substrate specificity in protein serine/threonine kinases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 1, 2003, Pages 74-79

  Brinkworth, Ross I ^a   Breinl, Robert A ^a   Kobe, Bostjan ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN SERINE THREONINE KINASE;

AMINO ACID SEQUENCE; ARTICLE; CELL CYCLE; CRYSTAL STRUCTURE; DNA DAMAGE; ENZYME BINDING; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; YEAST;

AMINO ACID SEQUENCE; BINDING SITES; CELL CYCLE; CONSENSUS SEQUENCE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DATABASES, PROTEIN; DNA DAMAGE; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PROTEIN-SERINE-THREONINE KINASES; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; SOFTWARE; SUBSTRATE SPECIFICITY;

EID: 0037422596     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0134224100     Document Type: Article

References (44)

1. Songyang, Z., Blechner, S., Hoagland, N., Hoekstra, M. F., Piwnica-Worms, H. & Cantley, L. C. (1994) Curr. Biol. 4, 973-982.
2. Hardie, D. G. (1999) Protein Phosphorylation (Oxford Univ. Press, Oxford).
3. Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W. & Lipman, D. J. (1997) Nucleic Acids Res. 25, 3389-3402.
4. Ponting, C. P., Schultz, J., Milpetz, F. & Bork, P. (1999) Nucleic Acids Res. 27, 229-232.
5. Bishop, A. C., Ubersax, J. A., Petsch, D. T., Matheos, D. P., Gray, N. S., Blethrow, J., Shimizu, E., Tsien, J. Z., Schultz, P. G., Rose, M. D., et al. (2000) Nature 407, 395-401.
6. Zhu, H., Klemic, J. F., Chang, S., Bertone, P., Casamayor, A., Klemic, K. G., Smith, D., Gerstein, M., Reed, M. A. & Snyder, M. (2000) Nat. Genet. 26, 283-289.
7. Knighton, D. R., Zheng, J., Ten Eyck, L. F., Ashford, V. A., Xuong, N.-H., Taylor, S. S. & Sowadski, J. M. (1991) Science 253, 407-414.
8. Bossemeyer, D., Engh, R. A., Kinzel, V., Postingl, H. & Huber, R. (1993) EMBO J. 12, 849-859.
9. Madhusudan, Trafny, E. A., Xuong, N.-H., Adams, J. A., Ten Eyck, L. F., Taylor, S. S. & Sowadski, J. M. (1994) Protein Sci. 3, 176-187.
10. Lowe, E. D., Noble, M. E., Skamnaki, V. T., Oikonomakos, N. G., Owen, D. J. & Johnson, L. N. (1997) EMBO J. 16, 6646-6658.
11. Brown, N. R., Noble, M. E., Endicott, J. A. & Johnson, L. N. (1999) Nat. Cell Biol. 1, 438-443.
12. Hanks, S. K. & Quinn, A. M. (1991) Methods Enzymol. 200, 38-62.
13. Hofmann, K., Bucher, P., Falquet, L. & Bairoch, A. (1999) Nucleic Acids Res. 27, 215-219.
14. Yaffe, M. B., Leparc, G. G., Lai, J., Obata, T., Volinia, S. & Cantley, L. C. (2001) Nat. Biotechnol. 19, 348-353.
15. Songyang, Z., Lu, K. P., Kwon, Y. T., Tsai, L. H., Filhol, O., Cochet, C., Brickey, D. A., Soderling, T. R., Bartleson, C., Graves, D. J., et al. (1996) Mol. Cell. Biol. 16, 6486-6493.
16. Nishikawa, K., Toker, A., Johannes, F. J., Songyang, Z. & Cantley, L. C. (1997) J. Biol. Chem. 272, 952-960.
17. Obata, T., Yaffe, M. B., Leparc, G. G., Piro, E. T., Maegawa, H., Kashiwagi, A., Kikkawa, R. & Cantley, L. C. (2000) J. Biol. Chem. 275, 36108-36115.
18. Pearson, R. B. & Kemp, B. E. (1991) Methods Enzymol. 200, 62-81.
19. O'Neill, T., Giarratani, L., Chen, P., Iyer, L., Lee, C. H., Bobiak, M., Kanai, F., Zhou, B. B., Chung, J. H. & Rathbun, G. A. (2002) J. Biol. Chem. 277, 16102-16115.
20. Kreegipuu, A., Blom, N. & Brunak, S. (1999) Nucleic Acids Res. 27, 237-239.
21. Uetz, P., Giot, L., Cagney, G., Mansfield, T. A., Judson, R. S., Knight, J. R., Lockshon, D., Narayan, V., Srinivasan, M., Pochart, P., et al. (2000) Nature 403, 623-627.
22. Gavin, A. C., Bosche, M., Krause, R., Grandi, P., Marzioch, M., Bauer, A., Schultz, J., Rick, J. M., Michon, A. M., Cruciat, C. M., et al. (2002) Nature 415, 141-147.
23. Ho, Y., Gruhler, A., Heilbut, A., Bader, G. D., Moore, L., Adams, S. L., Millar, A., Taylor, P., Bennett, K., Boutilier, K., et al. (2002) Nature 415, 180-183.
24. Ito, T., Chiba, T., Ozawa, R., Yoshida, M., Hattori, M. & Sakaki, Y. (2001) Proc. Natl. Acad. Sci. USA 98, 4569-4574.
25. Pawson, T. & Scott, J. D. (1997) Science 278, 2075-2080.
26. Hunter, T. & Plowman, G. D. (1997) Trends Biochem. Sci. 22, 18-22.
27. Mendenhall, M. D. & Hodge, A. E. (1998) Microbiol. Mol. Biol. Rev. 62, 1191-1243.
28. Cid, V. J., Shulewitz, M. J., McDonald, K. L. & Thorner, J. (2001) Mol. Biol. Cell 12, 1645-1669.
29. Sreenivasan, A. & Kellogg, D. (1999) Mol. Cell. Biol. 19, 7983-7994.
30. Edgington, N. P., Blacketer, M. J., Bierwagen, T. A. & Myers, A. M. (1999) Mol. Cell. Biol. 19, 1369-1380.
31. Durocher, D. & Jackson, S. P. (2001) Curr. Opin. Cell Biol. 13, 225-231.
32. Wang, H., Liu, D., Wang, Y., Qin, J. & Elledge, S. J. (2001) Genes Dev. 15, 1361-1372.
33. Myung, K., Datta, A. & Kolodner, R. D. (2001) Cell 104, 397-408.
34. Moore, C. W. (1978) Mutat. Res. 51, 165-180.
35. Zhao, X. & Rothstein, R. (2002) Proc. Natl. Acad. Sci. USA 99, 3746-3751.
36. Tsukamoto, Y., Taggart, A. K. & Zakian, V. A. (2001) Curr. Biol. 11, 1328-1335.
37. Haracska, L., Prakash, S. & Prakash, L. (2002) J. Biol. Chem. 277, 15546-15551.
38. Roberts, B. T., Farr, K. A. & Hoyt, M. A. (1994) Mol. Cell. Biol. 14, 8282-8291.
39. Kim, S. T., Xu, B. & Kastan, M. B. (2002) Genes Dev. 16, 560-570.
40. Sanchez, Y., Bachant, J., Wang, H., Hu, F., Liu, D., Tetzlaff, M. & Elledge, S. J. (1999) Science 286, 1166-1171.
41. Huang, M., Zhou, Z. & Elledge, S. J. (1998) Cell 94, 595-605.
42. Blom, N., Gammeltoft, S. & Brunak, S. (1999) J. Mol. Biol. 294, 1351-1562.
43. Nicholls, A., Sharp, K. A. & Honig, B. (1991) Proteins 11, 281-296.
44. Philips, J. & Herskowitz, I. (1998) J. Cell Biol. 143, 375-389.