메뉴 건너뛰기




Volumn 5, Issue , 2014, Pages

Snail1-dependent control of embryonic stem cell pluripotency and lineage commitment

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR SNAIL1; UNCLASSIFIED DRUG; WNT PROTEIN; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR;

EID: 84892151082     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4070     Document Type: Article
Times cited : (57)

References (71)
  • 2
    • 33750442483 scopus 로고    scopus 로고
    • Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm
    • DOI 10.1242/dev.02551
    • Lindsley, R. C., Gill, J. G., Kyba, M., Murphy, T. L. & Murphy, K. M. Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development 133, 3787-3796 (2006). (Pubitemid 44650957)
    • (2006) Development , vol.133 , Issue.19 , pp. 3787-3796
    • Lindsley, R.C.1    Gill, J.G.2    Kyba, M.3    Murphy, T.L.4    Murphy, K.M.5
  • 3
    • 54949102409 scopus 로고    scopus 로고
    • Wnt signaling mediates self-organization and axis formation in embryoid bodies
    • Ten Berge, D. et al. Wnt signaling mediates self-organization and axis formation in embryoid bodies. Cell Stem Cell 3, 508-518 (2008).
    • (2008) Cell Stem Cell , vol.3 , pp. 508-518
    • Ten Berge, D.1
  • 4
    • 84880269637 scopus 로고    scopus 로고
    • Snail1 controls TGF-beta responsiveness and differentiation of mesenchymal stem cells
    • Batlle, R. et al. Snail1 controls TGF-beta responsiveness and differentiation of mesenchymal stem cells. Oncogene 32, 3381-3389 (2013).
    • (2013) Oncogene , vol.32 , pp. 3381-3389
    • Batlle, R.1
  • 5
    • 79955419817 scopus 로고    scopus 로고
    • Snail and the microRNA-200 family act in opposition to regulate epithelial-to-mesenchymal transition and germ layer fate restriction in differentiating ESCs
    • Gill, J. G. et al. Snail and the microRNA-200 family act in opposition to regulate epithelial-to-mesenchymal transition and germ layer fate restriction in differentiating ESCs. Stem Cells 29, 764-776 (2011).
    • (2011) Stem Cells , vol.29 , pp. 764-776
    • Gill, J.G.1
  • 6
    • 84855830390 scopus 로고    scopus 로고
    • Snail promotes the cell-autonomous generation of Flk1(\+) endothelial cells through the repression of the microRNA-200 family
    • Gill, J. G. et al. Snail promotes the cell-autonomous generation of Flk1(\+) endothelial cells through the repression of the microRNA-200 family. Stem Cells Dev. 21, 167-176 (2012).
    • (2012) Stem Cells Dev. , vol.21 , pp. 167-176
    • Gill, J.G.1
  • 7
    • 77957551870 scopus 로고    scopus 로고
    • A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
    • Li, R. et al. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell 7, 51-63 (2010).
    • (2010) Cell Stem Cell , vol.7 , pp. 51-63
    • Li, R.1
  • 8
    • 77956320116 scopus 로고    scopus 로고
    • Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming
    • Samavarchi-Tehrani, P. et al. Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell 7, 64-77 (2010).
    • (2010) Cell Stem Cell , vol.7 , pp. 64-77
    • Samavarchi-Tehrani, P.1
  • 10
    • 84863895600 scopus 로고    scopus 로고
    • Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity
    • Wu, Z. Q. et al. Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity. Proc. Natl Acad. Sci. USA 109, 11312-11317 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 11312-11317
    • Wu, Z.Q.1
  • 11
    • 15744374449 scopus 로고    scopus 로고
    • Wnt-dependent regulation of the E-cadherin repressor snail
    • DOI 10.1074/jbc.M413878200
    • Yook, J. I., Li, X. Y., Ota, I., Fearon, E. R. & Weiss, S. J. Wnt-dependent regulation of the E-cadherin repressor Snail. J. Biol. Chem. 280, 11740-11748 (2005). (Pubitemid 40418488)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.12 , pp. 11740-11748
    • Jong, I.Y.1    Li, X.-Y.2    Ota, I.3    Fearon, E.R.4    Weiss, S.J.5
  • 13
    • 80052475509 scopus 로고    scopus 로고
    • Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells
    • Ten Berge, D. et al. Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells. Nat. Cell Biol. 13, 1070-1075 (2011).
    • (2011) Nat. Cell Biol. , vol.13 , pp. 1070-1075
    • Ten Berge, D.1
  • 14
    • 80053063127 scopus 로고    scopus 로고
    • Maintaining embryonic stem cell pluripotency with Wnt signaling
    • Sokol, S. Y. Maintaining embryonic stem cell pluripotency with Wnt signaling. Development 138, 4341-4350 (2011).
    • (2011) Development , vol.138 , pp. 4341-4350
    • Sokol, S.Y.1
  • 15
    • 84873050284 scopus 로고    scopus 로고
    • Regulatory networks defining EMT during cancer initiation and progression
    • De Craene, B. & Berx, G. Regulatory networks defining EMT during cancer initiation and progression. Nat. Rev. Cancer 13, 97-110 (2013).
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 97-110
    • De Craene, B.1    Berx, G.2
  • 16
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery, J. P., Acloque, H., Huang, R. Y. & Nieto, M. A. Epithelial-mesenchymal transitions in development and disease. Cell 139, 871-890 (2009).
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 17
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • DOI 10.1038/ng.127, PII NG127
    • Ben-Porath, I. et al. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat. Genet. 40, 499-507 (2008). (Pubitemid 351601215)
    • (2008) Nature Genetics , vol.40 , Issue.5 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3    Ge, R.4    Bell, G.W.5    Regev, A.6    Weinberg, R.A.7
  • 18
    • 41449118521 scopus 로고    scopus 로고
    • Module map of stem cell genes guides creation of epithelial cancer stem cells
    • DOI 10.1016/j.stem.2008.02.009, PII S1934590908000738
    • Wong, D. J. et al. Module map of stem cell genes guides creation of epithelial cancer stem cells. Cell Stem Cell 2, 333-344 (2008). (Pubitemid 351455242)
    • (2008) Cell Stem Cell , vol.2 , Issue.4 , pp. 333-344
    • Wong, D.J.1    Liu, H.2    Ridky, T.W.3    Cassarino, D.4    Segal, E.5    Chang, H.Y.6
  • 19
    • 78651100119 scopus 로고    scopus 로고
    • Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures
    • Mizuno, H., Spike, B. T., Wahl, G. M. & Levine, A. J. Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures. Proc. Natl Acad. Sci. USA 107, 22745-22750 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 22745-22750
    • Mizuno, H.1    Spike, B.T.2    Wahl, G.M.3    Levine, A.J.4
  • 20
    • 79952213086 scopus 로고    scopus 로고
    • Using a stem cell-based signature to guide therapeutic selection in cancer
    • Shats, I. et al. Using a stem cell-based signature to guide therapeutic selection in cancer. Cancer Res. 71, 1772-1780 (2011).
    • (2011) Cancer Res. , vol.71 , pp. 1772-1780
    • Shats, I.1
  • 21
    • 51449085561 scopus 로고    scopus 로고
    • Generation of breast cancer stem cells through epithelialmesenchymal transition
    • Morel, A. P. et al. Generation of breast cancer stem cells through epithelialmesenchymal transition. PLoS One 3, e2888 (2008).
    • (2008) PLoS One , vol.3
    • Morel, A.P.1
  • 22
    • 77957262381 scopus 로고    scopus 로고
    • Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
    • Taube, J. H. et al. Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc. Natl Acad. Sci. USA 107, 15449-15454 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 15449-15454
    • Taube, J.H.1
  • 23
    • 77957583439 scopus 로고    scopus 로고
    • Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition
    • Yang, M. H. et al. Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition. Nat. Cell Biol. 12, 982-992 (2010).
    • (2010) Nat. Cell Biol. , vol.12 , pp. 982-992
    • Yang, M.H.1
  • 24
    • 79959994448 scopus 로고    scopus 로고
    • SNAIL regulates interleukin-8 expression, stem cell-like activity, and tumorigenicity of human colorectal carcinoma cells
    • Hwang, W. L. et al. SNAIL regulates interleukin-8 expression, stem cell-like activity, and tumorigenicity of human colorectal carcinoma cells. Gastroenterology 141, 279-291 (2011).
    • (2011) Gastroenterology , vol.141 , pp. 279-291
    • Hwang, W.L.1
  • 25
    • 84857817163 scopus 로고    scopus 로고
    • Slug and Sox9 cooperatively determine the mammary stem cell state
    • Guo, W. et al. Slug and Sox9 cooperatively determine the mammary stem cell state. Cell 148, 1015-1028 (2012).
    • (2012) Cell , vol.148 , pp. 1015-1028
    • Guo, W.1
  • 26
    • 84879983245 scopus 로고    scopus 로고
    • Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity
    • Chaffer, C. L. et al. Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Cell 154, 61-74 (2013).
    • (2013) Cell , vol.154 , pp. 61-74
    • Chaffer, C.L.1
  • 27
    • 84874512754 scopus 로고    scopus 로고
    • A membrane-associated beta-catenin/Oct4 complex correlates with ground-state pluripotency in mouse embryonic stem cells
    • Faunes, F. et al. A membrane-associated beta-catenin/Oct4 complex correlates with ground-state pluripotency in mouse embryonic stem cells. Development 140, 1171-1183 (2013).
    • (2013) Development , vol.140 , pp. 1171-1183
    • Faunes, F.1
  • 28
    • 79959963618 scopus 로고    scopus 로고
    • Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal
    • Yi, F. et al. Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal. Nat. Cell Biol. 13, 762-770 (2011).
    • (2011) Nat. Cell Biol. , vol.13 , pp. 762-770
    • Yi, F.1
  • 29
    • 84875461910 scopus 로고    scopus 로고
    • Tcf7l1 prepares epiblast cells in the gastrulating mouse embryo for lineage specification
    • Hoffman, J. A., Wu, C. I. & Merrill, B. J. Tcf7l1 prepares epiblast cells in the gastrulating mouse embryo for lineage specification. Development 140, 1665-1675 (2013).
    • (2013) Development , vol.140 , pp. 1665-1675
    • Hoffman, J.A.1    Wu, C.I.2    Merrill, B.J.3
  • 30
    • 84892442959 scopus 로고    scopus 로고
    • Regulation of Tcf7l1 DNA binding and protein stability as principal mechanisms of Wnt/beta-catenin signaling
    • Shy, B. R. et al. Regulation of Tcf7l1 DNA binding and protein stability as principal mechanisms of Wnt/beta-catenin signaling. Cell Rep. 4, 1-9 (2013).
    • (2013) Cell Rep. , vol.4 , pp. 1-9
    • Shy, B.R.1
  • 31
    • 84878522915 scopus 로고    scopus 로고
    • Wnt signaling regulates the lineage differentiation potential of mouse embryonic stem cells through Tcf3 down-regulation
    • Atlasi, Y. et al. Wnt signaling regulates the lineage differentiation potential of mouse embryonic stem cells through Tcf3 down-regulation. PLoS Genet. 9, e1003424 (2013).
    • (2013) PLoS Genet. , vol.9
    • Atlasi, Y.1
  • 32
    • 79959950773 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation
    • Wray, J. et al. Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation. Nat. Cell Biol. 13, 838-845 (2011).
    • (2011) Nat. Cell Biol. , vol.13 , pp. 838-845
    • Wray, J.1
  • 33
    • 79959999016 scopus 로고    scopus 로고
    • Differential requirement for the dual functions of betacatenin in embryonic stem cell self-renewal and germ layer formation
    • Lyashenko, N. et al. Differential requirement for the dual functions of betacatenin in embryonic stem cell self-renewal and germ layer formation. Nat. Cell Biol. 13, 753-761 (2011).
    • (2011) Nat. Cell Biol. , vol.13 , pp. 753-761
    • Lyashenko, N.1
  • 34
    • 84892178502 scopus 로고    scopus 로고
    • Modulation of beta-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal
    • Kim, H. et al. Modulation of beta-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal. Nat. Commun. 4, 2403 (2013).
    • (2013) Nat. Commun. , vol.4 , Issue.2403
    • Kim, H.1
  • 35
    • 58249122326 scopus 로고    scopus 로고
    • Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
    • Chen, B. et al. Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nat. Chem. Biol. 5, 100-107 (2009).
    • (2009) Nat. Chem. Biol. , vol.5 , pp. 100-107
    • Chen, B.1
  • 36
    • 44349170450 scopus 로고    scopus 로고
    • The ground state of embryonic stem cell self-renewal
    • Ying, Q. L. et al. The ground state of embryonic stem cell self-renewal. Nature 453, 519-523 (2008).
    • (2008) Nature , vol.453 , pp. 519-523
    • Ying, Q.L.1
  • 37
    • 34247226529 scopus 로고    scopus 로고
    • Gene function in mouse embryogenesis: Get set for gastrulation
    • DOI 10.1038/nrg2084, PII NRG2084
    • Tam, P. P. & Loebel, D. A. Gene function in mouse embryogenesis: get set for gastrulation. Nat. Rev. Genet. 8, 368-381 (2007). (Pubitemid 46625808)
    • (2007) Nature Reviews Genetics , vol.8 , Issue.5 , pp. 368-381
    • Tam, P.P.L.1    Loebel, D.A.F.2
  • 38
    • 78149500053 scopus 로고    scopus 로고
    • Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages
    • Han, D. W. et al. Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages. Cell 143, 617-627 (2010).
    • (2010) Cell , vol.143 , pp. 617-627
    • Han, D.W.1
  • 39
    • 80052511434 scopus 로고    scopus 로고
    • The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation
    • Costello, I. et al. The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation. Nat. Cell Biol. 13, 1084-1091 (2011).
    • (2011) Nat. Cell Biol. , vol.13 , pp. 1084-1091
    • Costello, I.1
  • 40
    • 0035167812 scopus 로고    scopus 로고
    • The mouse Snail gene encodes a key regulator of the epithelial- mesenchymal transition
    • DOI 10.1128/MCB.21.23.8184-8188.2001
    • Carver, E. A., Jiang, R., Lan, Y., Oram, K. F. & Gridley, T. The mouse Snail gene encodes a key regulator of the epithelial-mesenchymal transition. Mol. Cell Biol. 21, 8184-8188 (2001). (Pubitemid 33051806)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.23 , pp. 8184-8188
    • Carver, E.A.1    Jiang, R.2    Lan, Y.3    Oram, K.F.4    Gridley, T.5
  • 41
    • 79959281790 scopus 로고    scopus 로고
    • Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos
    • Biechele, S., Cox, B. J. & Rossant, J. Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos. Dev. Biol. 355, 275-285 (2011).
    • (2011) Dev. Biol. , vol.355 , pp. 275-285
    • Biechele, S.1    Cox, B.J.2    Rossant, J.3
  • 42
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • DOI 10.1038/nrm1835, PII NRM1835
    • Thiery, J. P. & Sleeman, J. P. Complex networks orchestrate epithelialmesenchymal transitions. Nat. Rev. Mol. Cell Biol. 7, 131-142 (2006). (Pubitemid 43278296)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.2 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 43
    • 84878987773 scopus 로고    scopus 로고
    • The SNAI1 and SNAI2 proteins occupy their own and each other's promoter during chondrogenesis
    • Chen, Y. & Gridley, T. The SNAI1 and SNAI2 proteins occupy their own and each other's promoter during chondrogenesis. Biochem. Biophys. Res. Commun. 435, 356-360 (2013).
    • (2013) Biochem. Biophys. Res. Commun. , vol.435 , pp. 356-360
    • Chen, Y.1    Gridley, T.2
  • 44
    • 84055216937 scopus 로고    scopus 로고
    • Temporal and spatial cooperation of Snail1 and Twist1 during epithelial-mesenchymal transition predicts for human breast cancer recurrence
    • Tran, D. D., Corsa, C. A., Biswas, H., Aft, R. L. & Longmore, G. D. Temporal and spatial cooperation of Snail1 and Twist1 during epithelial-mesenchymal transition predicts for human breast cancer recurrence. Mol. Cancer Res. 9, 1644-1657 (2011).
    • (2011) Mol. Cancer Res. , vol.9 , pp. 1644-1657
    • Tran, D.D.1    Corsa, C.A.2    Biswas, H.3    Aft, R.L.4    Longmore, G.D.5
  • 45
    • 79953325707 scopus 로고    scopus 로고
    • Functional cooperation between Snail1 and Twist in the regulation of ZEB1 expression during epithelial to mesenchymal transition
    • Dave, N. et al. Functional cooperation between Snail1 and Twist in the regulation of ZEB1 expression during epithelial to mesenchymal transition. J. Biol. Chem. 286, 12024-12032 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 12024-12032
    • Dave, N.1
  • 46
    • 63349102395 scopus 로고    scopus 로고
    • Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs
    • Rowe, R. G. et al. Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs. J. Cell Biol. 184, 399-408 (2009).
    • (2009) J. Cell Biol. , vol.184 , pp. 399-408
    • Rowe, R.G.1
  • 47
    • 10944241060 scopus 로고    scopus 로고
    • Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation
    • DOI 10.1242/jcs.01489
    • Hamazaki, T., Oka, M., Yamanaka, S. & Terada, N. Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation. J. Cell Sci. 117, 5681-5686 (2004). (Pubitemid 40012213)
    • (2004) Journal of Cell Science , vol.117 , Issue.23 , pp. 5681-5686
    • Hamazaki, T.1    Oka, M.2    Yamanaka, S.3    Terada, N.4
  • 48
    • 77958133875 scopus 로고    scopus 로고
    • Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection
    • Gutierrez-Aranda, I. et al. Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection. Stem Cells 28, 1568-1570 (2010).
    • (2010) Stem Cells , vol.28 , pp. 1568-1570
    • Gutierrez-Aranda, I.1
  • 51
    • 78149487692 scopus 로고    scopus 로고
    • Pluripotency and cellular reprogramming: Facts, hypotheses, unresolved issues
    • Hanna, J. H., Saha, K. & Jaenisch, R. Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues. Cell 143, 508-525 (2010).
    • (2010) Cell , vol.143 , pp. 508-525
    • Hanna, J.H.1    Saha, K.2    Jaenisch, R.3
  • 52
    • 70350627509 scopus 로고    scopus 로고
    • Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells
    • Bao, S. et al. Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells. Nature 461, 1292-1295 (2009).
    • (2009) Nature , vol.461 , pp. 1292-1295
    • Bao, S.1
  • 54
    • 84880437964 scopus 로고    scopus 로고
    • MicroRNA-200a regulates Grb2 and suppresses differentiation of mouse embryonic stem cells into endoderm and mesoderm
    • Liu, Y. et al. MicroRNA-200a regulates Grb2 and suppresses differentiation of mouse embryonic stem cells into endoderm and mesoderm. PLoS One 8, e68990 (2013).
    • (2013) PLoS One , vol.8
    • Liu, Y.1
  • 57
    • 84866369892 scopus 로고    scopus 로고
    • Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase
    • Buganim, Y. et al. Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase. Cell 150, 1209-1222 (2012).
    • (2012) Cell , vol.150 , pp. 1209-1222
    • Buganim, Y.1
  • 58
    • 84860578009 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells
    • Celia-Terrassa, T. et al. Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells. J. Clin. Invest. 122, 1849-1868 (2012).
    • (2012) J. Clin. Invest. , vol.122 , pp. 1849-1868
    • Celia-Terrassa, T.1
  • 59
    • 84868347607 scopus 로고    scopus 로고
    • Metabolic plasticity in stem cell homeostasis and differentiation
    • Folmes, C. D., Dzeja, P. P., Nelson, T. J. & Terzic, A. Metabolic plasticity in stem cell homeostasis and differentiation. Cell Stem Cell 11, 596-606 (2012).
    • (2012) Cell Stem Cell , vol.11 , pp. 596-606
    • Folmes, C.D.1    Dzeja, P.P.2    Nelson, T.J.3    Terzic, A.4
  • 60
    • 84876434755 scopus 로고    scopus 로고
    • Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer
    • Dong, C. et al. Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer. Cancer Cell 23, 316-331 (2013).
    • (2013) Cancer Cell , vol.23 , pp. 316-331
    • Dong, C.1
  • 61
    • 84863917176 scopus 로고    scopus 로고
    • Wnt/Snail signaling regulates cytochrome C oxidase and glucose metabolism
    • Lee, S. Y. et al. Wnt/Snail signaling regulates cytochrome C oxidase and glucose metabolism. Cancer Res. 72, 3607-3617 (2012).
    • (2012) Cancer Res. , vol.72 , pp. 3607-3617
    • Lee, S.Y.1
  • 62
    • 84867028809 scopus 로고    scopus 로고
    • Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors
    • Blauwkamp, T. A., Nigam, S., Ardehali, R., Weissman, I. L. & Nusse, R. Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors. Nat. Commun. 3, 1070 (2012).
    • (2012) Nat. Commun. , vol.3 , pp. 1070
    • Blauwkamp, T.A.1    Nigam, S.2    Ardehali, R.3    Weissman, I.L.4    Nusse, R.5
  • 63
    • 84879676304 scopus 로고    scopus 로고
    • Porcn-dependent Wnt signaling is not required prior to mouse gastrulation
    • Biechele, S., Cockburn, K., Lanner, F., Cox, B. J. & Rossant, J. Porcn-dependent Wnt signaling is not required prior to mouse gastrulation. Development 140, 2961-2971 (2013).
    • (2013) Development , vol.140 , pp. 2961-2971
    • Biechele, S.1    Cockburn, K.2    Lanner, F.3    Cox, B.J.4    Rossant, J.5
  • 64
    • 84872416333 scopus 로고    scopus 로고
    • Wnt3 function in the epiblast is required for the maintenance but not the initiation of gastrulation in mice
    • Tortelote, G. G. et al. Wnt3 function in the epiblast is required for the maintenance but not the initiation of gastrulation in mice. Dev. Biol. 374, 164-173 (2013).
    • (2013) Dev. Biol. , vol.374 , pp. 164-173
    • Tortelote, G.G.1
  • 65
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling and disease
    • Clevers, H. & Nusse, R. Wnt/beta-catenin signaling and disease. Cell 149, 1192-1205 (2012).
    • (2012) Cell , vol.149 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 66
    • 70349645539 scopus 로고    scopus 로고
    • MiR-200 enhances mouse breast cancer cell colonization to form distant metastases
    • Dykxhoorn, D. M. et al. miR-200 enhances mouse breast cancer cell colonization to form distant metastases. PLoS One 4, e7181 (2009).
    • (2009) PLoS One , vol.4
    • Dykxhoorn, D.M.1
  • 67
    • 80052470207 scopus 로고    scopus 로고
    • Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization
    • Korpal, M. et al. Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nat. Med. 17, 1101-1108 (2011).
    • (2011) Nat. Med. , vol.17 , pp. 1101-1108
    • Korpal, M.1
  • 68
    • 54549108997 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition (EMT) is not sufficient for spontaneous murine breast cancer metastasis
    • Lou, Y. et al. Epithelial-mesenchymal transition (EMT) is not sufficient for spontaneous murine breast cancer metastasis. Dev. Dyn. 237, 2755-2768 (2008).
    • (2008) Dev. Dyn. , vol.237 , pp. 2755-2768
    • Lou, Y.1
  • 69
    • 77957757417 scopus 로고    scopus 로고
    • A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs
    • Kim, J. et al. A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs. Cell 143, 313-324 (2010).
    • (2010) Cell , vol.143 , pp. 313-324
    • Kim, J.1
  • 70
    • 84868224872 scopus 로고    scopus 로고
    • Control of breast cancer growth and initiation by the stem cell-associated transcription factor TCF3
    • Slyper, M. et al. Control of breast cancer growth and initiation by the stem cell-associated transcription factor TCF3. Cancer Res. 72, 5613-5624 (2012).
    • (2012) Cancer Res. , vol.72 , pp. 5613-5624
    • Slyper, M.1
  • 71
    • 84861849934 scopus 로고    scopus 로고
    • Reduced oxygen concentration enhances conversion of embryonic stem cells to epiblast stem cells
    • Takehara, T., Teramura, T., Onodera, Y., Hamanishi, C. & Fukuda, K. Reduced oxygen concentration enhances conversion of embryonic stem cells to epiblast stem cells. Stem Cells Dev. 21, 1239-1249 (2012).
    • (2012) Stem Cells Dev. , vol.21 , pp. 1239-1249
    • Takehara, T.1    Teramura, T.2    Onodera, Y.3    Hamanishi, C.4    Fukuda, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.