Acute exposure to high-fat diets increases hepatic expression of genes related to cell repair and remodeling in female rats

Nutrition Research

Volumn 34, Issue 1, 2014, Pages 85-93

  Miller, Colette N ^a   Morton, Heidi P ^b   Cooney, Paula T ^c   Winters, Tricia G ^c   Ramseur, Keshia R ^c   Rayalam, Srujana ^d   Della Fera, Mary Anne ^e   Baile, Clifton A ^a,e   Brown, Lynda M ^c  

^a UNIVERSITY OF GEORGIA   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

^c UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

^d PHILADELPHIA COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

^e UNIVERSITY OF GEORGIA   (United States)

Author keywords

Body composition; High fat diet; Lipogenesis; Motor activity; Rat; Regeneration; Sex characteristics

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY FAT; CALORIC INTAKE; CELL REGENERATION; DOWN REGULATION; FEMALE; GENE EXPRESSION; INFLAMMATION; LIPID DIET; LIPOGENESIS; LIVER; LIVER METABOLISM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEX DIFFERENCE; UPREGULATION;

ACC1; ACETYL CO-A CARBOXYLASE; ADIPOSE TRIGLYCERIDE LIPASE; ANNEXIN 5; ANXA5; ATGL; BBC3; BCL-2 BINDING COMPONENT 3; BGN; BIGLYCAN; BODY COMPOSITION; CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN 1; CASP2; CASPASE 2; CREB1; DGAT1; DIGLYCERIDE ACYLTRANSFERASE; FAS; FATTY ACID SYNTHASE; FIBRONECTIN; FN1; GATA BINDING PROTEIN 3; GATA3; HFD; HIGH-FAT DIET; IL6; INTERLEUKIN 6; JAK2; JANUS KINASE 2; LFD; LIPOGENESIS; LOW-FAT DIET; MADH1; MAPK; MATRIX METALLOPEPTIDASE 11; MITOGEN-ACTIVATED PROTEIN KINASE; MMP11; MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 1; MOTOR ACTIVITY; NEUROPEPTIDE Y; NPY; OSTEONECTIN; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR Γ; PPARΓ; RAT; REGENERATION; SCD1; SERPIN PEPTIDASE INHIBITOR CLADE H MEMBER 1; SERPINH1; SEX CHARACTERISTICS; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3; SOCS3; SPARC; SREBP1C; STAT3; STEROL CO-A DESATURASE; STEROL REGULATORY ELEMENT-BINDING PROTEIN 1; SUPPRESSOR OF CYTOKINE SIGNALING 3; TNFΑ; TUMOR NECROSIS FACTOR Α; VASCULAR ENDOTHELIAL GROWTH FACTOR; VEGF; X-BOX BINDING PROTEIN; XBP1;

ANIMALS; APOPTOSIS; BODY COMPOSITION; DIET, HIGH-FAT; DNA-BINDING PROTEINS; ENERGY INTAKE; FEMALE; GENE EXPRESSION REGULATION; INFLAMMATION; LIPOGENESIS; LIVER; MALE; PHYSICAL EXERTION; RATS; RATS, LONG-EVANS; SEX FACTORS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; WEIGHT GAIN;

EID: 84892146401     PISSN: 02715317     EISSN: 18790739     Source Type: Journal    
DOI: 10.1016/j.nutres.2013.10.010     Document Type: Article

References (37)

1. Glimcher L.H., Lee A.H. From sugar to fat: How the transcription factor XBP1 regulates hepatic lipogenesis. Ann N Y Acad Sci 2009, 1173(Suppl 1):E2-E9.
2. Birkenfeld A.L., Lee H.Y., Guebre-Egziabher F., Alves T.C., Jurczak M.J., Jornayvaz F.R., et al. Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice. Cell Metab 2011, 14:184-195.
3. Wang Y.C., McPherson K., Marsh T., Gortmaker S.L., Brown M. Health and economic burden of the projected obesity trends in the USA and the UK. Lancet 2011, 378:815-825.
4. Woods S.C., Seeley R.J., Rushing P.A., D'Alessio D.A., Tso P. A controlled high-fat diet induces an obese syndrome in rats. J Nutr 2003, 133:1081-1087.
5. Boghossian S., Lemmon K., Park M., York D.A. High-fat diets induce a rapid loss of the insulin anorectic response in the amygdala. Am J Physiol Regul Integr Comp Physiol 2009, 297:R1302-R1311.
6. Clegg D.J., Gotoh K., Kemp C., Wortman M.D., Benoit S.C., Brown L.M., et al. Consumption of a high-fat diet induces central insulin resistance independent of adiposity. Physiol Behav 2011, 103:10-16.
7. Lee Y.S., Li P., Huh J.Y., Hwang I.J., Lu M., Kim J.I., et al. Inflammation is necessary for long-term but not short-term high-fat diet-induced insulin resistance. Diabetes 2011, 60:2474-2483.
8. Mullen K.L., Tishinsky J.M., Robinson L.E., Dyck D.J. Skeletal muscle inflammation is not responsible for the rapid impairment in adiponectin response with high-fat feeding in rats. Am J Physiol Regul Integr Comp Physiol 2010, 299:R500-R508.
9. Ren L.P., Chan S.M., Zeng X.Y., Laybutt D.R., Iseli T.J., Sun R.Q., et al. Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance. PLoS One 2012, 7:e30816.
10. Brown M.S., Goldstein J.L. Selective versus total insulin resistance: a pathogenic paradox. Cell Metab 2008, 7:95-96.
11. Shi H., Clegg D.J. Sex differences in the regulation of body weight. Physiol Behav 2009, 97:199-204.
12. Gao H., Bryzgalova G., Hedman E., Khan A., Efendic S., Gustafsson J.A., et al. Long-term administration of estradiol decreases expression of hepatic lipogenic genes and improves insulin sensitivity in ob/ob mice: a possible mechanism is through direct regulation of signal transducer and activator of transcription 3. Mol Endocrinol 2006, 20:1287-1299.
13. Maffei L., Murata Y., Rochira V., Tubert G., Aranda C., Vazquez M., et al. Dysmetabolic syndrome in a man with a novel mutation of the aromatase gene: effects of testosterone, alendronate, and estradiol treatment. J Clin Endocrinol Metab 2004, 89:61-70.
14. Paquette A., Wang D., Jankowski M., Gutkowska J., Lavoie J.M. Effects of ovariectomy on PPAR alpha, SREBP-1c, and SCD-1 gene expression in the rat liver. Menopause 2008, 15:1169-1175.
15. Becker J.B., Arnold A.P., Berkley K.J., Blaustein J.D., Eckel L.A., Hampson E., et al. Strategies and methods for research on sex differences in brain and behavior. Endocrinology 2005, 146:1650-1673.
16. Clegg D.J., Brown L.M., Woods S.C., Benoit S.C. Gonadal hormones determine sensitivity to central leptin and insulin. Diabetes 2006, 55:978-987.
17. Hirota M., Kitagaki M., Itagaki H., Aiba S. Quantitative measurement of spliced XBP1 mRNA as an indicator of endoplasmic reticulum stress. J Toxicol Sci 2006, 31:149-156.
18. Faul F., Erdfelder E., Lang A.G., Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 2007, 39:175-191.
19. Stafford J.M., Yu F., Printz R., Hasty A.H., Swift L.L., Niswender K.D. Central nervous system neuropeptide Y signaling modulates VLDL triglyceride secretion. Diabetes 2008, 57:1482-1490.
20. Hewitt K.N., Pratis K., Jones M.E., Simpson E.R. Estrogen replacement reverses the hepatic steatosis phenotype in the male aromatase knockout mouse. Endocrinology 2004, 145:1842-1848.
21. Brun T., Assimacopoulos-Jeannet F., Corkey B.E., Prentki M. Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1. Diabetes 1997, 46:393-400.
22. Wilson M.D., Blake W.L., Salati L.M., Clarke S.D. Potency of polyunsaturated and saturated fats as short-term inhibitors of hepatic lipogenesis in rats. J Nutr 1990, 120:544-552.
23. Lee A.H., Scapa E.F., Cohen D.E., Glimcher L.H. Regulation of hepatic lipogenesis by the transcription factor XBP1. Science 2008, 320:1492-1496.
24. Wei Y., Wang D., Topczewski F., Pagliassotti M.J. Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells. Am J Physiol Endocrinol Metab 2006, 291:E275-E281.
25. Kozlov A.V., Duvigneau J.C., Hyatt T.C., Raju R., Behling T., Hartl R.T., et al. Effect of estrogen on mitochondrial function and intracellular stress markers in rat liver and kidney following trauma-hemorrhagic shock and prolonged hypotension. Mol Med 2010, 16:254-261.
26. Wang D.Y., Fulthorpe R., Liss S.N., Edwards E.A. Identification of estrogen-responsive genes by complementary deoxyribonucleic acid microarray and characterization of a novel early estrogen-induced gene: EEIG1. Mol Endocrinol 2004, 18:402-411.
27. Eguchi K., Manabe I., Oishi-Tanaka Y., Ohsugi M., Kono N., Ogata F., et al. Saturated fatty acid and TLR signaling link beta cell dysfunction and islet inflammation. Cell Metab 2012, 15:518-533.
28. Sachithanandan N., Fam B.C., Fynch S., Dzamko N., Watt M.J., Wormald S., et al. Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity. Hepatology 2010, 52:1632-1642.
29. Senn J.J., Klover P.J., Nowak I.A., Zimmers T.A., Koniaris L.G., Furlanetto R.W., et al. Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes. J Biol Chem 2003, 278:13740-13746.
30. Ueki K., Kondo T., Tseng Y.H., Kahn C.R. Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse. Proc Natl Acad Sci U S A 2004, 101:10422-10427.
31. Lanthier N., Molendi-Coste O., Horsmans Y., van Rooijen N., Cani P.D., Leclercq I.A. Kupffer cell activation is a causal factor for hepatic insulin resistance. Am J Physiol Gastrointest Liver Physiol 2010, 298:G107-G116.
32. Kim D.H., Sandoval D., Reed J.A., Matter E.K., Tolod E.G., Woods S.C., et al. The role of GM-CSF in adipose tissue inflammation. Am J Physiol Endocrinol Metab 2008, 295:E1038-E1046.
33. Kim J.H., Bachmann R.A., Chen J. Interleukin-6 and insulin resistance. Vitam Horm 2009, 80:613-633.
34. Guicciardi M.E., Gores G.J. Apoptosis: a mechanism of acute and chronic liver injury. Gut 2005, 54:1024-1033.
35. Seli E., Guzeloglu-Kayisli O., Kayisli U.A., Kizilay G., Arici A. Estrogen increases apoptosis in the arterial wall in a murine atherosclerosis model. Fertil Steril 2007, 88:1190-1196.
36. Straub R.H. The complex role of estrogens in inflammation. Endocr Rev 2007, 28:521-574.
37. Nagasue N., Kohno H. Hepatocellular carcinoma and sex hormones. HPB Surg 1992, 6:1-6.