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Volumn 89, Issue 1, 2004, Pages 61-70

Dysmetabolic Syndrome in a Man with a Novel Mutation of the Aromatase Gene: Effects of Testosterone, Alendronate, and Estradiol Treatment

Author keywords

[No Author keywords available]

Indexed keywords

ALENDRONIC ACID; ANDROGEN; AROMATASE; ESTRADIOL; ESTROGEN; GLUCOSE; GONADOTROPIN; LIPID; TESTOSTERONE ENANTATE;

EID: 10744225853     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2003-030313     Document Type: Conference Paper
Times cited : (299)

References (44)
  • 2
    • 0033305438 scopus 로고    scopus 로고
    • Estrogen receptor null mice: What we learned and where will they lead us?
    • Couse JF, Korach KS 1999 Estrogen receptor null mice: what we learned and where will they lead us? Endocr Rev 20:358-417
    • (1999) Endocr Rev , vol.20 , pp. 358-417
    • Couse, J.F.1    Korach, K.S.2
  • 4
    • 0028792229 scopus 로고
    • Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens
    • Morishima A, Grumbach MM, Simpson ER, Fisher C, Qin K 1995 Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens. J Clin Endocrinol Metab 80:3689-3698
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 3689-3698
    • Morishima, A.1    Grumbach, M.M.2    Simpson, E.R.3    Fisher, C.4    Qin, K.5
  • 6
    • 0032572929 scopus 로고    scopus 로고
    • Increased bone mass as a result of estrogen therapy in a man with aromatase deficiency
    • Bilezikian JF, Morishima A, Bell J, Grumbach MM 1998 Increased bone mass as a result of estrogen therapy in a man with aromatase deficiency. N Engl J Med 339:599-603
    • (1998) N Engl J Med , vol.339 , pp. 599-603
    • Bilezikian, J.F.1    Morishima, A.2    Bell, J.3    Grumbach, M.M.4
  • 7
    • 0034457013 scopus 로고    scopus 로고
    • Estrogen replacement therapy in a man with congenital aromatase deficiency: Effects of different doses of transdermal estradiol on bone mineral density and hormonal parameters
    • Rochira V, Faustini-Fustini M, Balestrieri A, Carani C 2000 Estrogen replacement therapy in a man with congenital aromatase deficiency: effects of different doses of transdermal estradiol on bone mineral density and hormonal parameters. J Clin Endocrinol Metab 85:1841-1845
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1841-1845
    • Rochira, V.1    Faustini-Fustini, M.2    Balestrieri, A.3    Carani, C.4
  • 10
    • 0034521393 scopus 로고    scopus 로고
    • Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men
    • Falahati-Nini A, Riggs BL, Atkinson EJ, O'Fallon WM, Eastell R, Khosla S 2000 Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men. J Clin Invest 106:1553-1560
    • (2000) J Clin Invest , vol.106 , pp. 1553-1560
    • Falahati-Nini, A.1    Riggs, B.L.2    Atkinson, E.J.3    O'Fallon, W.M.4    Eastell, R.5    Khosla, S.6
  • 11
  • 12
    • 0036224094 scopus 로고    scopus 로고
    • Oestrogen, bones and men: When testosterone just isn't enough
    • Khosla S 2002 Oestrogen, bones and men: when testosterone just isn't enough. Clin Endocrinol 56:291-293
    • (2002) Clin Endocrinol , vol.56 , pp. 291-293
    • Khosla, S.1
  • 13
    • 0036078456 scopus 로고    scopus 로고
    • Pituitary function in a man with congenital aromatase deficiency: Effect of different doses of transdermal E2 on basal and stimulated pituitary hormones
    • Rochira V, Balestrieri A, Faustini-Fustini M, Borgato S, Beck-Peccoz P, Carani C 2002 Pituitary function in a man with congenital aromatase deficiency: effect of different doses of transdermal E2 on basal and stimulated pituitary hormones. J Clin Endocrinol Metab 87:2857-2862
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2857-2862
    • Rochira, V.1    Balestrieri, A.2    Faustini-Fustini, M.3    Borgato, S.4    Beck-Peccoz, P.5    Carani, C.6
  • 16
    • 0031154045 scopus 로고    scopus 로고
    • Aromatase deficiency in a female who is compound heterozygote for two new point mutations in the P450arom gene: Impact of estrogens on hypergonadotropic hypogonadism, multicystic ovaries, and bone densitometry in childhood
    • Mullis PE, Yoshimura N, Kuhlmann B, Lippuner K, Jaeger P, Harada H 1997 Aromatase deficiency in a female who is compound heterozygote for two new point mutations in the P450arom gene: impact of estrogens on hypergonadotropic hypogonadism, multicystic ovaries, and bone densitometry in childhood. J Clin Endocrinol Metab 82:1739-1745
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1739-1745
    • Mullis, P.E.1    Yoshimura, N.2    Kuhlmann, B.3    Lippuner, K.4    Jaeger, P.5    Harada, H.6
  • 17
    • 0006656956 scopus 로고
    • Isolation of a full-length cDNA insert encoding human aromatase system cytochrome P-450 and its expression in nonsteroidogenic cells
    • Corbin CJ, Graham-Lorence S, McPhaul M, Mason JI, Mendelson CR, Simpson ER 1988 Isolation of a full-length cDNA insert encoding human aromatase system cytochrome P-450 and its expression in nonsteroidogenic cells. Proc Natl Acad Sci USA 85:8948-8952
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 8948-8952
    • Corbin, C.J.1    Graham-Lorence, S.2    McPhaul, M.3    Mason, J.I.4    Mendelson, C.R.5    Simpson, E.R.6
  • 21
    • 0033305733 scopus 로고    scopus 로고
    • Estrogen: Consequences and implications of human mutations in synthesis and action
    • Grumbach MM, Auchus RJ 1999 Estrogen: consequences and implications of human mutations in synthesis and action. J Clin Endocrinol Metab 84:4677-4694
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 4677-4694
    • Grumbach, M.M.1    Auchus, R.J.2
  • 22
    • 0035346926 scopus 로고    scopus 로고
    • Editorial: The role of combination treatment for osteoporosis
    • Recker RR, Heaney RP 2001 Editorial: the role of combination treatment for osteoporosis. J Clin Endocrinol Metab 86:1888-1889
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1888-1889
    • Recker, R.R.1    Heaney, R.P.2
  • 23
    • 0037205931 scopus 로고    scopus 로고
    • Congenital estrogen deficiency in men: A new syndrome with different phenotypes; clinical and therapeutic implications in men
    • Rochira V, Balestrieri A, Madeo B, Spaggiari A, Carani C 2002 Congenital estrogen deficiency in men: a new syndrome with different phenotypes; clinical and therapeutic implications in men. Mol Cell Endocrinol 193:19-28
    • (2002) Mol Cell Endocrinol , vol.193 , pp. 19-28
    • Rochira, V.1    Balestrieri, A.2    Madeo, B.3    Spaggiari, A.4    Carani, C.5
  • 24
    • 0035143822 scopus 로고    scopus 로고
    • Differential regulation of gonadotropin secretion by testosterone in the human male: Absence of a negative feedback effect of testosterone on follicle-stimulating hormone secretion
    • Hayes FJ, Decruz S, Seminara SB, Boepple PE, Crowley WF 2001 Differential regulation of gonadotropin secretion by testosterone in the human male: absence of a negative feedback effect of testosterone on follicle-stimulating hormone secretion. J Clin Endocrinol Metab 86:53-58
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 53-58
    • Hayes, F.J.1    Decruz, S.2    Seminara, S.B.3    Boepple, P.E.4    Crowley, W.F.5
  • 26
    • 0036159351 scopus 로고    scopus 로고
    • Early postnatal treatment of hypogonadotropic hypogonadism with recombinant human FSH and LH
    • Main KM, Schmidt IM, Toppari J, Skakkebaek NE 2002 Early postnatal treatment of hypogonadotropic hypogonadism with recombinant human FSH and LH. Eur J Endocrinol 146:75-79
    • (2002) Eur J Endocrinol , vol.146 , pp. 75-79
    • Main, K.M.1    Schmidt, I.M.2    Toppari, J.3    Skakkebaek, N.E.4
  • 29
    • 0037291609 scopus 로고    scopus 로고
    • Progressive development of insulin resistance phenotype in male mice with complete aromatase (CYP19) deficiency
    • Takeda K, Toda K, Saibara T, Nakagawa M, Saika K, Onishi T, Sugiura T, Shizuta Y 2003 Progressive development of insulin resistance phenotype in male mice with complete aromatase (CYP19) deficiency. J Endocrinol 176: 237-246
    • (2003) J Endocrinol , vol.176 , pp. 237-246
    • Takeda, K.1    Toda, K.2    Saibara, T.3    Nakagawa, M.4    Saika, K.5    Onishi, T.6    Sugiura, T.7    Shizuta, Y.8
  • 32
    • 0027967086 scopus 로고
    • Serum testosterone level is the major determinant of the male-female differences in serum levels of high-density lipoprotein (HDL) cholesterol and HDL2 cholesterol
    • Asscheman H, Gooren LJ, Megens JA, Nauta J, Kloosterboer HJ, Eikelboom F 1994 Serum testosterone level is the major determinant of the male-female differences in serum levels of high-density lipoprotein (HDL) cholesterol and HDL2 cholesterol. Metabolism 43:935-939
    • (1994) Metabolism , vol.43 , pp. 935-939
    • Asscheman, H.1    Gooren, L.J.2    Megens, J.A.3    Nauta, J.4    Kloosterboer, H.J.5    Eikelboom, F.6
  • 33
    • 0030952581 scopus 로고    scopus 로고
    • Suppression of endogenous testosterone in young men increases serum levels of high density lipoprotein subclass lipoprotein A-I and lipoprotein(a)
    • von Eckardstein A, Kliesch S, Nieschlag E, Chirazi A, Assmann G, Behre HM 1997 Suppression of endogenous testosterone in young men increases serum levels of high density lipoprotein subclass lipoprotein A-I and lipoprotein(a). J Clin Endocrinol Metab 82:3367-3372
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 3367-3372
    • Von Eckardstein, A.1    Kliesch, S.2    Nieschlag, E.3    Chirazi, A.4    Assmann, G.5    Behre, H.M.6
  • 37
  • 38
    • 0033542402 scopus 로고    scopus 로고
    • The protective effects of estrogen on the cardiovascular system
    • Mendelsohn ME, Karas RH 1999 The protective effects of estrogen on the cardiovascular system. N Engl J Med 340:1801-1811
    • (1999) N Engl J Med , vol.340 , pp. 1801-1811
    • Mendelsohn, M.E.1    Karas, R.H.2
  • 40
  • 42
    • 0034835056 scopus 로고    scopus 로고
    • Hormone replacement therapy may improve hepatic function in women with Turner's syndrome
    • Elsheikh M, Hodgson HJ, Wass JA, Conway GS 2001 Hormone replacement therapy may improve hepatic function in women with Turner's syndrome. Clin Endocrinol 55:227-231
    • (2001) Clin Endocrinol , vol.55 , pp. 227-231
    • Elsheikh, M.1    Hodgson, H.J.2    Wass, J.A.3    Conway, G.S.4
  • 43
    • 0036144667 scopus 로고    scopus 로고
    • Aromatase inhibitors for male infertility
    • Raman JD, Schlegel PN 2002 Aromatase inhibitors for male infertility. J Urol 167:624-629
    • (2002) J Urol , vol.167 , pp. 624-629
    • Raman, J.D.1    Schlegel, P.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.