메뉴 건너뛰기




Volumn 138, Issue 1, 2013, Pages 47-57

Loss of E-cadherin is not a necessity for epithelial to mesenchymal transition in human breast cancer

Author keywords

Basal subtype; Caveolin 1; E cadherin; EMT; Metaplastic breast cancer; Spindle cell morphology

Indexed keywords

CAVEOLIN 1; UVOMORULIN;

EID: 84874647804     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-013-2415-3     Document Type: Article
Times cited : (117)

References (45)
  • 1
    • 23144442645 scopus 로고    scopus 로고
    • Regulation of cadherin-mediated adhesion in morphogenesis
    • 16025097 10.1038/nrm1699 1:CAS:528:DC%2BD2MXmvVGhtrk%3D
    • Gumbiner BM (2005) Regulation of cadherin-mediated adhesion in morphogenesis. Nat Rev Mol Cell Biol 6:622-634
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 622-634
    • Gumbiner, B.M.1
  • 2
    • 57349114162 scopus 로고    scopus 로고
    • The cell-cell adhesion molecule E-cadherin
    • van Roy F, Berx G (2008) The cell-cell adhesion molecule E-cadherin. Cell Mol Life Sci 65(23):3756-3788
    • (2008) Cell Mol Life Sci , vol.65 , Issue.23 , pp. 3756-3788
    • Van Roy, F.1    Berx, G.2
  • 3
    • 33750459738 scopus 로고    scopus 로고
    • Catenins: Keeping cells from getting their signals crossed
    • 17084354 10.1016/j.devcel.2006.10.010 1:CAS:528:DC%2BD28Xht1Smsr%2FN
    • Perez-Moreno M, Fuchs E (2006) Catenins: keeping cells from getting their signals crossed. Dev Cell 11:601-612
    • (2006) Dev Cell , vol.11 , pp. 601-612
    • Perez-Moreno, M.1    Fuchs, E.2
  • 4
    • 33845716602 scopus 로고    scopus 로고
    • Cinderella no longer: Alpha-catenin steps out of cadherin's shadow
    • 17093264 10.1242/jcs.03267 1:CAS:528:DC%2BD2sXktF2n
    • Scott JA, Yap AS (2006) Cinderella no longer: alpha-catenin steps out of cadherin's shadow. J Cell Sci 119:4599-4605
    • (2006) J Cell Sci , vol.119 , pp. 4599-4605
    • Scott, J.A.1    Yap, A.S.2
  • 5
    • 0031686121 scopus 로고    scopus 로고
    • Mutations of the human E-cadherin (CDH1) gene
    • 9744472 10.1002/(SICI)1098-1004(1998)12:4<226: AID-HUMU2>3.0.CO;2-D 1:CAS:528:DyaK1cXmtFWqsr8%3D
    • Berx G, Becker KF, Hofler H, van Roy F (1998) Mutations of the human E-cadherin (CDH1) gene. Hum Mutat 12:226-237
    • (1998) Hum Mutat , vol.12 , pp. 226-237
    • Berx, G.1    Becker, K.F.2    Hofler, H.3    Van Roy, F.4
  • 6
    • 0037051099 scopus 로고    scopus 로고
    • CDH1 mutations are present in both ductal and lobular breast cancer, but promoter allelic variants show no detectable breast cancer risk
    • 11857408 10.1002/ijc.10176 1:CAS:528:DC%2BD38XhsVSktbg%3D
    • Lei H, Sjoberg-Margolin S, Salahshor S, Werelius B, Jandakova E, Hemminki K, Lindblom A, Vorechovsky I (2002) CDH1 mutations are present in both ductal and lobular breast cancer, but promoter allelic variants show no detectable breast cancer risk. Int J Cancer 98:199-204
    • (2002) Int J Cancer , vol.98 , pp. 199-204
    • Lei, H.1    Sjoberg-Margolin, S.2    Salahshor, S.3    Werelius, B.4    Jandakova, E.5    Hemminki, K.6    Lindblom, A.7    Vorechovsky, I.8
  • 9
    • 34249289041 scopus 로고    scopus 로고
    • Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
    • 17508028 10.1038/nrc2131 1:CAS:528:DC%2BD2sXls1Kjs70%3D
    • Peinado H, Olmeda D, Cano A (2007) Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer 7:415-428
    • (2007) Nat Rev Cancer , vol.7 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 11
    • 54049084380 scopus 로고    scopus 로고
    • A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
    • 18829540 10.1158/0008-5472.CAN-08-1942 1:CAS:528:DC%2BD1cXhtF2msLzK
    • Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J, Shannon MF, Goodall GJ (2008) A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res 68:7846-7854
    • (2008) Cancer Res , vol.68 , pp. 7846-7854
    • Bracken, C.P.1    Gregory, P.A.2    Kolesnikoff, N.3    Bert, A.G.4    Wang, J.5    Shannon, M.F.6    Goodall, G.J.7
  • 12
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • 18483486 10.1038/embor.2008.74 1:CAS:528:DC%2BD1cXmsFykt7Y%3D
    • Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, Brabletz T (2008) A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 9:582-589
    • (2008) EMBO Rep , vol.9 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3    Schmalhofer, O.4    Vincan, E.5    Spaderna, S.6    Brabletz, T.7
  • 13
    • 39449095723 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype
    • 18281472 10.1158/0008-5472.CAN-07-2017 1:CAS:528:DC%2BD1cXhvFemu7Y%3D
    • Sarrio D, Rodriguez-Pinilla SM, Hardisson D, Cano A, Moreno-Bueno G, Palacios J (2008) Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype. Cancer Res 68:989-997
    • (2008) Cancer Res , vol.68 , pp. 989-997
    • Sarrio, D.1    Rodriguez-Pinilla, S.M.2    Hardisson, D.3    Cano, A.4    Moreno-Bueno, G.5    Palacios, J.6
  • 14
    • 37149040456 scopus 로고    scopus 로고
    • Molecular signatures of metaplastic carcinoma of the breast by large-scale transcriptional profiling: Identification of genes potentially related to epithelial-mesenchymal transition
    • 17603561 10.1038/sj.onc.1210593 1:CAS:528:DC%2BD2sXhsVaisr%2FN
    • Lien HC, Hsiao YH, Lin YS, Yao YT, Juan HF, Kuo WH, Hung MC, Chang KJ, Hsieh FJ (2007) Molecular signatures of metaplastic carcinoma of the breast by large-scale transcriptional profiling: identification of genes potentially related to epithelial-mesenchymal transition. Oncogene 26:7859-7871
    • (2007) Oncogene , vol.26 , pp. 7859-7871
    • Lien, H.C.1    Hsiao, Y.H.2    Lin, Y.S.3    Yao, Y.T.4    Juan, H.F.5    Kuo, W.H.6    Hung, M.C.7    Chang, K.J.8    Hsieh, F.J.9
  • 15
    • 33947230755 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines
    • 17314276 10.1158/1541-7786.MCR-06-0263 1:CAS:528:DC%2BD2sXhvFWrtb8%3D
    • Hollestelle A, Elstrodt F, Nagel JH, Kallemeijn WW, Schutte M (2007) Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines. Mol Cancer Res 5:195-201
    • (2007) Mol Cancer Res , vol.5 , pp. 195-201
    • Hollestelle, A.1    Elstrodt, F.2    Nagel, J.H.3    Kallemeijn, W.W.4    Schutte, M.5
  • 17
    • 27144432408 scopus 로고    scopus 로고
    • How ADAM-9 and ADAM-11 differentially from estrogen receptor predict response to tamoxifen treatment in patients with recurrent breast cancer: A retrospective study
    • 16243802 10.1158/1078-0432.CCR-05-0560 1:CAS:528:DC%2BD2MXhtFartb3F
    • Sieuwerts AM, Meijer-van Gelder ME, Timmermans M, Trapman AM, Garcia RR, Arnold M, Goedheer AJ, Portengen H, Klijn JG, Foekens JA (2005) How ADAM-9 and ADAM-11 differentially from estrogen receptor predict response to tamoxifen treatment in patients with recurrent breast cancer: a retrospective study. Clin Cancer Res 11:7311-7321
    • (2005) Clin Cancer Res , vol.11 , pp. 7311-7321
    • Sieuwerts, A.M.1    Meijer-Van Gelder, M.E.2    Timmermans, M.3    Trapman, A.M.4    Garcia, R.R.5    Arnold, M.6    Goedheer, A.J.7    Portengen, H.8    Klijn, J.G.9    Foekens, J.A.10
  • 18
    • 33746714410 scopus 로고    scopus 로고
    • Thirteen new p53 gene mutants identified among 41 human breast cancer cell lines
    • 16541312 10.1007/s10549-006-9186-z 1:CAS:528:DC%2BD28XnslShsLk%3D
    • Wasielewski M, Elstrodt F, Klijn JG, Berns EM, Schutte M (2006) Thirteen new p53 gene mutants identified among 41 human breast cancer cell lines. Breast Cancer Res Treat 99:97-101
    • (2006) Breast Cancer Res Treat , vol.99 , pp. 97-101
    • Wasielewski, M.1    Elstrodt, F.2    Klijn, J.G.3    Berns, E.M.4    Schutte, M.5
  • 19
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • 11309499 10.1073/pnas.091062498 1:CAS:528:DC%2BD3MXjt1Ons7w%3D
    • Tusher VG, Tibshirani R, Chu G (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 98:5116-5121
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 24
    • 43549126870 scopus 로고    scopus 로고
    • Reduction of E-cadherin expression is associated with non-lobular breast carcinomas of basal-like and triple negative phenotype
    • 18156431 10.1136/jcp.2007.053991 1:STN:280:DC%2BD1c3nsFGhsA%3D%3D
    • Mahler-Araujo B, Savage K, Parry S, Reis-Filho JS (2008) Reduction of E-cadherin expression is associated with non-lobular breast carcinomas of basal-like and triple negative phenotype. J Clin Pathol 61:615-620
    • (2008) J Clin Pathol , vol.61 , pp. 615-620
    • Mahler-Araujo, B.1    Savage, K.2    Parry, S.3    Reis-Filho, J.S.4
  • 25
    • 77956262480 scopus 로고    scopus 로고
    • Molecular characterization of TGFbeta-induced epithelial-mesenchymal transition in normal finite lifespan human mammary epithelial cells
    • 20691661 10.1016/j.bbrc.2010.07.138 1:CAS:528:DC%2BC3cXhtFamsLfP
    • Lindley LE, Briegel KJ (2010) Molecular characterization of TGFbeta-induced epithelial-mesenchymal transition in normal finite lifespan human mammary epithelial cells. Biochem Biophys Res Commun 399:659-664
    • (2010) Biochem Biophys Res Commun , vol.399 , pp. 659-664
    • Lindley, L.E.1    Briegel, K.J.2
  • 28
    • 47549102418 scopus 로고    scopus 로고
    • Epithelial mesenchymal transition traits in human breast cancer cell lines
    • 18461285 10.1007/s10585-008-9170-6 1:STN:280:DC%2BD1cvltFelsA%3D%3D
    • Blick T, Widodo E, Hugo H, Waltham M, Lenburg ME, Neve RM, Thompson EW (2008) Epithelial mesenchymal transition traits in human breast cancer cell lines. Clin Exp Metastasis 25:629-642
    • (2008) Clin Exp Metastasis , vol.25 , pp. 629-642
    • Blick, T.1    Widodo, E.2    Hugo, H.3    Waltham, M.4    Lenburg, M.E.5    Neve, R.M.6    Thompson, E.W.7
  • 30
    • 33750358078 scopus 로고    scopus 로고
    • Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial- mesenchymal transition
    • 17018611 10.1158/0008-5472.CAN-06-0479 1:CAS:528:DC%2BD28XhtVamsrfE
    • Moreno-Bueno G, Cubillo E, Sarrio D, Peinado H, Rodriguez-Pinilla SM, Villa S, Bolos V, Jorda M, Fabra A, Portillo F, Palacios J, Cano A (2006) Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition. Cancer Res 66:9543-9556
    • (2006) Cancer Res , vol.66 , pp. 9543-9556
    • Moreno-Bueno, G.1    Cubillo, E.2    Sarrio, D.3    Peinado, H.4    Rodriguez-Pinilla, S.M.5    Villa, S.6    Bolos, V.7    Jorda, M.8    Fabra, A.9    Portillo, F.10    Palacios, J.11    Cano, A.12
  • 36
    • 33746708760 scopus 로고    scopus 로고
    • Caveolin-1 expression is associated with a basal-like phenotype in sporadic and hereditary breast cancer
    • 16541313 10.1007/s10549-006-9184-1 1:CAS:528:DC%2BD28XnslShsbo%3D
    • Pinilla SM, Honrado E, Hardisson D, Benitez J, Palacios J (2006) Caveolin-1 expression is associated with a basal-like phenotype in sporadic and hereditary breast cancer. Breast Cancer Res Treat 99:85-90
    • (2006) Breast Cancer Res Treat , vol.99 , pp. 85-90
    • Pinilla, S.M.1    Honrado, E.2    Hardisson, D.3    Benitez, J.4    Palacios, J.5
  • 37
    • 34548853409 scopus 로고    scopus 로고
    • Vimentin and laminin expression is associated with basal-like phenotype in both sporadic and BRCA1-associated breast carcinomas
    • 17105822 10.1136/jcp.2006.042143
    • Rodriguez-Pinilla SM, Sarrio D, Honrado E, Moreno-Bueno G, Hardisson D, Calero F, Benitez J, Palacios J (2007) Vimentin and laminin expression is associated with basal-like phenotype in both sporadic and BRCA1-associated breast carcinomas. J Clin Pathol 60:1006-1012
    • (2007) J Clin Pathol , vol.60 , pp. 1006-1012
    • Rodriguez-Pinilla, S.M.1    Sarrio, D.2    Honrado, E.3    Moreno-Bueno, G.4    Hardisson, D.5    Calero, F.6    Benitez, J.7    Palacios, J.8
  • 38
    • 44449111555 scopus 로고    scopus 로고
    • Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways
    • 18483246 10.1158/0008-5472.CAN-07-2938 1:CAS:528:DC%2BD1cXlvVOitLw%3D
    • Onder TT, Gupta PB, Mani SA, Yang J, Lander ES, Weinberg RA (2008) Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res 68:3645-3654
    • (2008) Cancer Res , vol.68 , pp. 3645-3654
    • Onder, T.T.1    Gupta, P.B.2    Mani, S.A.3    Yang, J.4    Lander, E.S.5    Weinberg, R.A.6
  • 41
    • 68949136025 scopus 로고    scopus 로고
    • Metaplastic breast carcinomas are basal-like breast cancers: A genomic profiling analysis
    • Weigelt B, Kreike B, Reis-Filho JS (2009) Metaplastic breast carcinomas are basal-like breast cancers: a genomic profiling analysis. Breast Cancer Res Treat 117:273-280
    • (2009) Breast Cancer Res Treat , vol.117 , pp. 273-280
    • Weigelt, B.1    Kreike, B.2    Reis-Filho, J.S.3
  • 44
    • 54449085718 scopus 로고    scopus 로고
    • Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers
    • 18806226 10.1073/pnas.0807146105 1:CAS:528:DC%2BD1cXht1aqur7P
    • Dumont N, Wilson MB, Crawford YG, Reynolds PA, Sigaroudinia M, Tlsty TD (2008) Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers. Proc Natl Acad Sci USA 105:14867-14872
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14867-14872
    • Dumont, N.1    Wilson, M.B.2    Crawford, Y.G.3    Reynolds, P.A.4    Sigaroudinia, M.5    Tlsty, T.D.6
  • 45
    • 84863770814 scopus 로고    scopus 로고
    • Cancer genetics and epigenetics: Two sides of the same coin?
    • 22789535 10.1016/j.ccr.2012.06.008 1:CAS:528:DC%2BC38XhtVSltb7K
    • You JS, Jones PA (2012) Cancer genetics and epigenetics: two sides of the same coin? Cancer Cell 22:9-20
    • (2012) Cancer Cell , vol.22 , pp. 9-20
    • You, J.S.1    Jones, P.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.