Evaluation of Zinc (II) chelators for inhibiting p53-mediated apoptosis

Oncotarget

Volumn 4, Issue 12, 2013, Pages 2439-2450

  Morita, Akinori ^a,b   Ariyasu, Shinya ^c   Ohya, Soichiro ^c   Takahashi, Ippei ^b   Wang, Bing ^d   Tanaka, Kaoru ^d   Uchida, Takatoshi ^c   Okazaki, Haruna ^c   Hanaya, Kengo ^c   Enomoto, Atsushi ^e   Nenoi, Mitsuru ^d   Ikekita, Masahiko ^c   Aoki, Shin ^c   Hosoi, Yoshio ^b  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c TOKYO UNIVERSITY OF SCIENCE   (Japan)

^d NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

Author keywords

Apoptosis; p53; Radiation; Zinc binding site; Zinc chelator

Indexed keywords

BISPICEN; CASPASE 10; CASPASE 3; CASPASE 7; PIFITHRIN ALPHA; PIFITHRIN MU; PROTEIN P53; RADIOPROTECTIVE AGENT; TETRAKIS(2 PYRIDYLMETHYL)ETHYLENEDIAMINE; UNCLASSIFIED DRUG; VANADATE SODIUM;

APOPTOSIS; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA BINDING; DRUG STRUCTURE; HUMAN; HUMAN CELL; PROTEIN DENATURATION; RADIATION PROTECTION; TRANSCRIPTION REGULATION;

ANIMALS; APOPTOSIS; CATIONS, DIVALENT; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CHELATING AGENTS; MICE; PROTEIN DENATURATION; RADIATION-PROTECTIVE AGENTS; TUMOR SUPPRESSOR PROTEIN P53; VANADATES; ZINC;

EID: 84891939016     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1535     Document Type: Article

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