Alignment of gold clusters on DNA via a DNA-recognizing zinc finger-metallothionein fusion protein

Bioconjugate Chemistry

Volumn 20, Issue 12, 2009, Pages 2278-2285

  Ariyasu, Shinya ^a   Onoda, Akira ^b   Sakamoto, Ryota ^a   Yamamura, Takeshi ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CIRCULAR DICHROISM SPECTROSCOPY; DICHROISM; ENERGY DISPERSIVE SPECTROSCOPY; FOURIER TRANSFORM INFRARED SPECTROSCOPY; HEAVY METALS; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; METAL IONS; METAL NANOPARTICLES; PROTEINS; VOLTAMMETRY; X RAY PHOTOELECTRON SPECTROSCOPY; ZINC;

AU CLUSTERS; AU NANOPARTICLE; BASE PAIR SEQUENCES; FOLDINGS; FUSION PROTEINS; GOLD CLUSTERS; METALLOTHIONEINS; ZINC FINGER; ZINC FINGER DOMAINS; ZN 2+;

DNA;

5,5A 2 DITHIOBIS(2 NITROBENZOIC ACID); CADMIUM; DNA; GOLD; HYBRID PROTEIN; METAL ION; METALLOTHIONEIN; NITROBENZOIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ABSORPTION; AMINO ACID SEQUENCE; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; DNA BINDING; GEL MOBILITY SHIFT ASSAY; METAL BINDING; ROENTGEN SPECTROSCOPY; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; TITRIMETRY; TRANSMISSION ELECTRON MICROSCOPY; X RAY PHOTOELECTRON SPECTROSCOPY; ZINC FINGER MOTIF;

RATTUS;

EID: 72449208566     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc9002713     Document Type: Article

References (35)

1. Storhoff, J. J., and Mirkin, C. A. (1999) Programmed materials synthesis with DNA. Chem. Rev. 99, 1849-1862.
2. Aldaye, F. A., and Sleiman, H. F. (2007) Dynamic DNA templates for discrete gold nanoparticle assemblies: control of geometry, modularity, write/erase and structural switching. J. Am. Chem. Soc. 129, 4130-4131.
3. Millar, J., McLachlan, A. D., and Klug, A. (1985) Repetitive zinc-binding domains in the protein transcription factor IIIA fron Xenopus oocytes. EMBO J. 4, 1609-1614.
4. Berg, J. M. (1986) Potential metal-binding domains in nucleic acid binding proteins. Science 232, 485-487.
5. Chan, J., Huang, Z., Merrifield, M. E., Salgado, M. T., and Stillman, M. J. (2002) Studies of metal binding reactions in metallothioneins by spectroscopic, molecular biology, and molecular modeling techniques. Coord. Chem. Rev. 233-234, 319-339.
6. Park, C., Campbell, J. L., and Goddard, W. A. (1996) Can the monomer of the leucine zipper proteins recognize the dimer binding site without dimerization? J. Am. Chem. Soc. 118, 4235-4239. (Pubitemid 26167542)
7. Bishop, P., Ghosh, I., Jones, C., and Chmielewski, J. (1995) Basic-helix-loop-helix region of Tal: evaluation of structure and DNA affinity. J. Am. Chem. Soc. 117, 8283-8284.
8. 2+ for binding sites in the glucocorticoid receptor. J. Am. Chem. Soc. 130, 8148-8149.
9. Marmorstein, R., Carey, M., Ptashne, M., and Hariison, S. C. (1992) DNA recognition by GAL4: structure of a protein-DNA complex. Nature 356, 408-414.
10. 2 zinc finger proteins. Annu. Rev. Biochem. 70, 313-340.
11. Jantz, D., Amann, B. T., Gregory, J., Gatto, J., and Berg, J. M. (2004) The design of functional DNA-binding proteins based on zinc finger domains. Chem. Rev. 104, 789-799.
12. Mandell, J. G., and Barbas, C. F. (2006) Zinc finger tools: custom DNA-binding domains for transcription factors and nucleases. Nucleic Acids Res. 34, W516-W523.
13. Choo, Y., and Klug, A.1994 Selection of DNA binding sites for zinc fingers using rationally randomized DNA reveals coded interactions. Proc. Natl. Acad. Sci. U.S.A. 91, 11168-11172. (Pubitemid 24349647)
14. Sera, T., and Uranga, C. (2002) Rational design of artificial zinc-finger proteins using a nondegenerate recognition code table. Biochemistry 41, 7074-7081. (Pubitemid 34575680)
15. Stillman, M. J., Cai, W., and Zelazowski, A. J. (1987) Cadmium Binding to metallothioneins. J. Biol. Chem. 262, 4538-4548.
16. Stillman, M. J., Presta, A., Gui, Z., and Jiang, D.-T. (1994) Spectroscopic studies of copper, silver and gold-metallothioneins. Metal Based Drugs 1, 375-394.
17. Kägi, J. H. R., and Schäffer, A. (1988) Biochemistry of metallothionein. Biochemistry 27, 8409-8515.
18. Robbins, A. H., McRee, D. E., Williamson, M., Collett, S. A., Xuong, N. H., Furey, W. F., Wang, B. C., and Stout, C. D. (1991) Refined crystal structure of Cd, Zn metallothionein at 2.0 A resolution. J. Mol. Biol. 221, 1269-1293. (Pubitemid 121003453)
19. Mercogliano, C. P., and DeRosier, D. J. (2006) Gold nano-cluster formation using metallothionein: mass spectrometry and electron microscopy. J. Mol. Biol. 355, 211-223.
20. Ariyasu, S., Onoda, A., Sakamoto, R., and Yamamura, T. (2009) Conjugation of Au11 cluster with Cys-rich peptides containing the R-domain of metallothionein. Dalton Trans. 3742-3747.
21. Bartiett, P. A., Bauer, B., and Singer, S. J. (1978) Synthesis of water-soluble undecagold cluster compounds of potential importance in electron microscopic and other studies of biological systems. J. Am. Chem. Soc. 100, 5085-5089.
22. Dawson, P. E., and Kent, S. B. H. (2000) Synthesis of native proteins by chemical ligation. Annu. Rev. Biochem. 69, 923-960.
23. Pavletich, N. P., and Pabo, C. O. (1991) Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 Å. Science 252, 809-817.
24. Futaki, S., Sogawa, K., Maruyama, J., Asahara, T., Niwa, M., and Hojo, H. (1997) Preparation of peptide thioesters using fmoc-solid-phase peptide synthesis and its application to the construction of a template-asssembled synthetic protein (TASP). Tetrahedron Lett. 38, 6237-6240. (Pubitemid 27362166)
25. 2 zinc finger peptide. Proc. Natl. Acad. Sci. U.S.A. 89, 4796-4800.
26. Frankel, A. D., Berg, J. M., and Pabo, C. O. (1987) Metal-dependent folding of a single zinc finger from transcription factor IIIA. Proc. Natl. Acad. Sci. U.S.A. 84, 4841-4845.
27. Hasler, D. W., Jensen, L. T., Zerbe, O., Winge, D. R., and Vašák, M. (2000) Effect of two conserved prolines of human growth inhibitory factor (metallothionein-3) on its biological activity and structure fluctuation: comparison with a mutant protein. Biochemistry 39, 14567-14575.
28. Blindauer, C. A., Harrison, M. D., Parkinson, J. A., Robinson, A. K., Cavet, J. S., Robbinson, N. J., and Sadler, P. J. (2001) A metallothionein containing a zinc finger within a four-metal cluster protects a bacterium from zinc toxicity. Proc. Natl. Acad. Sci. U.S.A. 98, 9593-9598.
29. Woehrle, G. H., and Hutchison, J. E. (2005) Thiol-functionalized undecagold clusters by ligand exchange: synthesis, mechanism, and properties. Inorg. Chem. 44, 6149-6158. (Pubitemid 41323461)
30. Fu, T., and Seeman, N. C. (1993) DNA double-crossover molecules. Biochemistry 32, 3211-3220.
31. Kim, C. A., and Berg, J. M. (1996) A 2.2 Å resolution crystal structure of a designed zinc finger protein bound to DNA. Nat. Struct. Biol. 3, 940-945. (Pubitemid 26398327)
32. Chi, L. F., Hartig, M., Drechsler, T., Schwaack, T., Seidel, C., Fuchs, H., and Schmid, G. (1998) Single-electron tunneling in Au55 cluster monolayers. Appl. Phys. A: Mater. Sci. Proc. 66, S187-S190.
33. 6 clusters and their electrical properties at room temperature. Nano Lett. 1, 405-407.
34. Lytton-Jean, A. K. R., Han, M. S., and Mirkin, C. A. (2007) Microarray detection of duplex and triplex DNA binders with DNA-modified gold nanoparticles. Anal. Chem. 79, 6037-6041.
35. Woehrle, G. H., Warner, M. G., and Hutchison, J. E. (2002) Ligand exchange reactions yield subnanometer, thiol-stabilized gold particles with defined optical transitions. J. Phys. Chem. B 106, 9979-9981.