Characterization of a new V gene replacement in the absence of activation-induced cytidine deaminase and its contribution to human B-cell receptor diversity

Immunology

Volumn 141, Issue 2, 2014, Pages 268-275

  Ouled Haddou, Hakim ^a   Ghamlouch, Hussein ^a   Regnier, Aline ^a   Trudel, Stephanie ^a,b   Herent, Didier ^b   Lefranc, Marie Paule ^c   Marolleau, Jean Pierre ^a,b   Gubler, Brigitte ^a,b  

^a UNIVERSITÉ DE PICARDIE JULES VERNE   (France)

^b AMIENS UNIVERSITY HOSPITAL   (France)

^c UMR 9002 CNRS UM   (France)

Author keywords

AICDA; B cell receptor immunoglobulin repertoire diversity; Gene conversion like recombination; IGKV replacement; Immunoglobulin ; Immunoglobulin genes

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; B LYMPHOCYTE RECEPTOR; IMMUNOGLOBULIN KAPPA CHAIN; INTERLEUKIN 1; RAG1 PROTEIN; RAG2 PROTEIN; TOLL LIKE RECEPTOR 4;

ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; GENE CONVERSION; GENE EXPRESSION; HAPLOTYPE; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IGKJ5 GENE; IGKV GENE; IGKV2 GENE; IGKV3 GENE; IMMUNOGLOBULIN GENE; LIGHT CHAIN; MULTIPLEX POLYMERASE CHAIN REACTION; PRE B LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AICDA; B-CELL RECEPTOR IMMUNOGLOBULIN REPERTOIRE DIVERSITY; GENE CONVERSION-LIKE RECOMBINATION; IGKV REPLACEMENT; IMMUNOGLOBULIN GENES; IMMUNOGLOBULIN Κ;

AMINO ACID SEQUENCE; BASE SEQUENCE; CELL LINE; CYTIDINE DEAMINASE; GENE REARRANGEMENT; HOMOLOGOUS RECOMBINATION; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN VARIABLE REGION; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MOLECULAR SEQUENCE DATA; RECEPTORS, ANTIGEN, B-CELL;

EID: 84891895074     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12192     Document Type: Article

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