메뉴 건너뛰기




Volumn 190, Issue 11, 2013, Pages 5559-5566

Regulation of VH replacement by B cell receptor-mediated signaling in human immature B cells

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD19 ANTIGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE SYK; PROTEIN TYROSINE KINASE; IMMUNOGLOBULIN HEAVY CHAIN; LYMPHOCYTE ANTIGEN RECEPTOR; SIGNAL PEPTIDE;

EID: 84878060069     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1102503     Document Type: Article
Times cited : (11)

References (46)
  • 1
    • 0024846088 scopus 로고
    • The V(D)J recombination activating gene, RAG-1
    • DOI 10.1016/0092-8674(89)90760-5
    • Schatz, D. G., M. A. Oettinger, and D. Baltimore. 1989. The V(D)J recombination activating gene, RAG-1. Cell 59: 1035-1048. (Pubitemid 20024615)
    • (1989) Cell , vol.59 , Issue.6 , pp. 1035-1048
    • Schatz, D.G.1    Oettinger, M.A.2    Baltimore, D.3
  • 2
    • 0026440855 scopus 로고
    • Activation of V(D)J recombination by RAG1 and RAG2
    • Oettinger, M. A. 1992. Activation of V(D)J recombination by RAG1 and RAG2. Trends Genet. 8: 413-416.
    • (1992) Trends Genet. , vol.8 , pp. 413-416
    • Oettinger, M.A.1
  • 3
    • 0028048275 scopus 로고
    • The mechanism of V(D)J joining: Lessons from molecular, immunological, and comparative analyses
    • Lewis, S. M. 1994. The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses. Adv. Immunol. 56: 27-150. (Pubitemid 24242222)
    • (1994) Advances in Immunology , vol.56 , pp. 27-150
    • Lewis, S.M.1
  • 4
    • 0842303307 scopus 로고    scopus 로고
    • Unraveling V(D)J Recombination: Insights into Gene Regulation
    • DOI 10.1016/S0092-8674(04)00039-X
    • Jung, D., and F. W. Alt. 2004. Unraveling V(D)J recombination; insights into gene regulation. Cell 116: 299-311. (Pubitemid 38167319)
    • (2004) Cell , vol.116 , Issue.2 , pp. 299-311
    • Jung, D.1    Alt, F.W.2
  • 5
    • 0030006070 scopus 로고    scopus 로고
    • Clonal selection and learning in the antibody system
    • DOI 10.1038/381751a0
    • Rajewsky, K. 1996. Clonal selection and learning in the antibody system. Nature 381: 751-758. (Pubitemid 26243107)
    • (1996) Nature , vol.381 , Issue.6585 , pp. 751-758
    • Rajewsky, K.1
  • 6
    • 0032442391 scopus 로고    scopus 로고
    • Immune receptor editing: Revise and select
    • DOI 10.1016/S0092-8674(00)81711-0
    • Nussenzweig, M. C. 1998. Immune receptor editing: revise and select. Cell 95: 875-878. (Pubitemid 29019039)
    • (1998) Cell , vol.95 , Issue.7 , pp. 875-878
    • Nussenzweig, M.C.1
  • 7
    • 0034608364 scopus 로고    scopus 로고
    • Revising B cell receptors
    • DOI 10.1084/jem.191.11.1813
    • Nemazee, D., and M. Weigert. 2000. Revising B cell receptors. J. Exp. Med. 191: 1813-1817. (Pubitemid 30390345)
    • (2000) Journal of Experimental Medicine , vol.191 , Issue.11 , pp. 1813-1817
    • Nemazee, D.1    Weigert, M.2
  • 9
    • 0027499537 scopus 로고
    • Receptor editing: An approach by autoreactive B cells to escape tolerance
    • Gay, D., T. Saunders, S. Camper, and M. Weigert. 1993. Receptor editing: an approach by autoreactive B cells to escape tolerance. J. Exp. Med. 177: 999-1008. (Pubitemid 23097389)
    • (1993) Journal of Experimental Medicine , vol.177 , Issue.4 , pp. 999-1008
    • Gay, D.1    Saunders, T.2    Camper, S.3    Weigert, M.4
  • 10
    • 0032487518 scopus 로고    scopus 로고
    • Receptor editing occurs frequently during normal B cell development
    • DOI 10.1084/jem.188.7.1231
    • Retter, M. W., and D. Nemazee. 1998. Receptor editing occurs frequently during normal B cell development. J. Exp. Med. 188: 1231-1238. (Pubitemid 28478011)
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.7 , pp. 1231-1238
    • Retter, M.W.1    Nemazee, D.2
  • 11
    • 0037375554 scopus 로고    scopus 로고
    • Antigen receptor selection by editing or downregulation of V(D)J recombination
    • DOI 10.1016/S0952-7915(03)00008-6
    • Nemazee, D., and K. A. Hogquist. 2003. Antigen receptor selection by editing or downregulation of V(D)J recombination. Curr. Opin. Immunol. 15: 182-189. (Pubitemid 36287524)
    • (2003) Current Opinion in Immunology , vol.15 , Issue.2 , pp. 182-189
    • Nemazee, D.1    Hogquist, K.A.2
  • 13
    • 0032559223 scopus 로고    scopus 로고
    • Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection
    • DOI 10.1016/S0092-8674(00)80912-5
    • Melamed, D., R. J. Benschop, J. C. Cambier, and D. Nemazee. 1998. Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection. Cell 92: 173-182. (Pubitemid 28073041)
    • (1998) Cell , vol.92 , Issue.2 , pp. 173-182
    • Melamed, D.1    Benschop, R.J.2    Cambier, J.C.3    Nemazee, D.4
  • 14
    • 0033103016 scopus 로고    scopus 로고
    • Negative selection of immature B cells by receptor editing or deletion is determined by site of antigen encounter
    • Sandel, P. C., and J. G. Monroe. 1999. Negative selection of immature B cells by receptor editing or deletion is determined by site of antigen encounter. Immunity 10: 289-299. (Pubitemid 29165284)
    • (1999) Immunity , vol.10 , Issue.3 , pp. 289-299
    • Sandel, P.C.1    Monroe, J.G.2
  • 15
    • 0022502863 scopus 로고
    • + B-cell lymphoma
    • Kleinfield, R., R. R. Hardy, D. Tarlinton, J. Dangl, L. A. Herzenberg, and M.Weigert. 1986. Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma. Nature 322: 843-846. (Pubitemid 16055258)
    • (1986) Nature , vol.322 , Issue.6082 , pp. 843-846
    • Kleinfield, R.1    Hardy, R.R.2    Tarlinton, D.3
  • 16
    • 0022557584 scopus 로고
    • H joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production
    • H joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production. Nature 322: 840-842.
    • (1986) Nature , vol.322 , pp. 840-842
    • Reth, M.1    Gehrmann, P.2    Petrac, E.3    Wiese, P.4
  • 17
    • 33847160642 scopus 로고    scopus 로고
    • VH replacement in mice and humans
    • Zhang, Z. 2007. VH replacement in mice and humans. Trends Immunol. 28: 132-137.
    • (2007) Trends Immunol. , vol.28 , pp. 132-137
    • Zhang, Z.1
  • 19
    • 0029553058 scopus 로고
    • Immunoglobulin heavy chain gene replacement: A mechanism of receptor editing
    • DOI 10.1016/1074-7613(95)90064-0
    • Chen, C., Z. Nagy, E. L. Prak, and M. Weigert. 1995. Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing. Immunity 3: 747-755. (Pubitemid 26091148)
    • (1995) Immunity , vol.3 , Issue.6 , pp. 747-755
    • Chen, C.1    Nagy, Z.2    Prak, E.L.3    Weigert, M.4
  • 21
    • 0030997499 scopus 로고    scopus 로고
    • Editing disease-associated autoantibodies
    • DOI 10.1016/S1074-7613(00)80673-1
    • Chen, C., E. L. Prak, and M. Weigert. 1997. Editing disease-associated autoantibodies. Immunity 6: 97-105. (Pubitemid 27130219)
    • (1997) Immunity , vol.6 , Issue.1 , pp. 97-105
    • Chen, C.1    Prak, E.L.2    Weigert, M.3
  • 22
    • 0031573516 scopus 로고    scopus 로고
    • H gene replacement in hyper-selected B cells of the quasimonoclonal mouse
    • H gene replacement in hyper-selected B cells of the quasimonoclonal mouse. J. Immunol. 159: 5795-5801.
    • (1997) J. Immunol. , vol.159 , pp. 5795-5801
    • Cascalho, M.1    Wong, J.2    Wabl, M.3
  • 24
    • 33750836920 scopus 로고    scopus 로고
    • H replacement rescues progenitor B cells with two nonproductive VDJ alleles
    • H replacement rescues progenitor B cells with two nonproductive VDJ alleles. J. Immunol. 177: 7007-7014.
    • (2006) J. Immunol. , vol.177 , pp. 7007-7014
    • Lutz, J.1    Müller, W.2    Jäck, H.M.3
  • 28
    • 37549037403 scopus 로고    scopus 로고
    • Multiple, conserved cryptic recombination signals in VH gene segments: Detection of cleavage products only in pro B cells
    • Davila, M., F. Liu, L. G. Cowell, A. E. Lieberman, E. Heikamp, A. Patel, and G. Kelsoe. 2007. Multiple, conserved cryptic recombination signals in VH gene segments: detection of cleavage products only in pro B cells. J. Exp. Med. 204: 3195-3208.
    • (2007) J. Exp. Med. , vol.204 , pp. 3195-3208
    • Davila, M.1    Liu, F.2    Cowell, L.G.3    Lieberman, A.E.4    Heikamp, E.5    Patel, A.6    Kelsoe, G.7
  • 30
    • 0037306952 scopus 로고    scopus 로고
    • V(D)J recombinatorial repertoire diversification during intraclonal pro-B to B-cell differentiation
    • DOI 10.1182/blood-2002-06-1828
    • Wang, Y. H., Z. Zhang, P. D. Burrows, H. Kubagawa, S. L. Bridges, Jr., H. W. Findley, and M. D. Cooper. 2003. V(D)J recombinatorial repertoire diversification during intraclonal pro-B to B-cell differentiation. Blood 101: 1030-1037. (Pubitemid 36139376)
    • (2003) Blood , vol.101 , Issue.3 , pp. 1030-1037
    • Wang, Y.-H.1    Zhang, Z.2    Burrows, P.D.3    Kubagawa, H.4    Bridges Jr., S.L.5    Findley, H.W.6    Cooper, M.D.7
  • 32
    • 30044450912 scopus 로고    scopus 로고
    • Single-strand recombination signal sequence nicks in vivo: Evidence for a capture model of synapsis
    • DOI 10.1038/ni1270, PII N1270
    • Curry, J. D., J. K. Geier, and M. S. Schlissel. 2005. Single-strand recombination signal sequence nicks in vivo: evidence for a capture model of synapsis. Nat. Immunol. 6: 1272-1279. (Pubitemid 43045639)
    • (2005) Nature Immunology , vol.6 , Issue.12 , pp. 1272-1279
    • Curry, J.D.1    Geier, J.K.2    Schlissel, M.S.3
  • 33
    • 0034767872 scopus 로고    scopus 로고
    • Expression of recombination-activating genes and terminal deoxynucleotidyl transferase and secondary rearrangement of immunoglobulin kappa light chains in rheumatoid arthritis synovial tissue
    • DOI 10.1002/1529-0131(200110)44:10<2275::AID-ART39
    • Zhang, Z., X. Wu, B. H. Limbaugh, and S. L. Bridges, Jr. 2001. Expression of recombination-activating genes and terminal deoxynucleotidyl transferase and secondary rearrangement of immunoglobulin kappa light chains in rheumatoid arthritis synovial tissue. Arthritis Rheum. 44: 2275-2284. (Pubitemid 32977495)
    • (2001) Arthritis and Rheumatism , vol.44 , Issue.10 , pp. 2275-2284
    • Zhang, Z.1    Wu, X.2    Limbaugh, B.H.3    Bridges Jr., S.L.4
  • 34
    • 19344376101 scopus 로고    scopus 로고
    • Identification and characterization of circulating human transitional B cells
    • DOI 10.1182/blood-2004-11-4284
    • Sims, G. P., R. Ettinger, Y. Shirota, C. H. Yarboro, G. G. Illei, and P. E. Lipsky. 2005. Identification and characterization of circulating human transitional B cells. Blood 105: 4390-4398. (Pubitemid 40720786)
    • (2005) Blood , vol.105 , Issue.11 , pp. 4390-4398
    • Sims, G.P.1    Ettinger, R.2    Shirota, Y.3    Yarboro, C.H.4    Illei, G.G.5    Lipsky, P.E.6
  • 35
    • 0030795735 scopus 로고    scopus 로고
    • Molecular mechanisms in B cell antigen receptor signaling
    • DOI 10.1016/S0952-7915(97)80075-1
    • Kurosaki, T. 1997. Molecular mechanisms in B cell antigen receptor signaling. Curr. Opin. Immunol. 9: 309-318. (Pubitemid 27303498)
    • (1997) Current Opinion in Immunology , vol.9 , Issue.3 , pp. 309-318
    • Kurosaki, T.1
  • 36
    • 0037204949 scopus 로고    scopus 로고
    • B cell antigen receptor signaling: Roles in cell development and disease
    • DOI 10.1126/science.1071546
    • Gauld, S. B., J. M. Dal Porto, and J. C. Cambier. 2002. B cell antigen receptor signaling: roles in cell development and disease. Science 296: 1641-1642. (Pubitemid 34579149)
    • (2002) Science , vol.296 , Issue.5573 , pp. 1641-1642
    • Gauld, S.B.1    Dal, P.J.M.2    Cambier, J.C.3
  • 37
    • 18844395578 scopus 로고    scopus 로고
    • Regulation of B lymphocyte activation by complement C3 and the B cell coreceptor complex
    • DOI 10.1016/j.coi.2005.03.001, PII S0952791505000397, Lymphocyte Activation/Lymphocyte Effector Functions
    • Rickert, R. C. 2005. Regulation of B lymphocyte activation by complement C3 and the B cell coreceptor complex. Curr. Opin. Immunol. 17: 237-243. (Pubitemid 40692657)
    • (2005) Current Opinion in Immunology , vol.17 , Issue.3 , pp. 237-243
    • Rickert, R.C.1
  • 38
    • 43049165459 scopus 로고    scopus 로고
    • New Insights into the Early Molecular Events Underlying B Cell Activation
    • DOI 10.1016/j.immuni.2008.04.007, PII S1074761308001970
    • Harwood, N. E., and F. D. Batista. 2008. New insights into the early molecular events underlying B cell activation. Immunity 28: 609-619. (Pubitemid 351636250)
    • (2008) Immunity , vol.28 , Issue.5 , pp. 609-619
    • Harwood, N.E.1    Batista, F.D.2
  • 39
    • 0036604452 scopus 로고    scopus 로고
    • Impaired light chain allelic exclusion and lack of positive selection in immature B cells expressing incompetent receptor deficient of CD19
    • Shivtiel, S., N. Leider, O. Sadeh, Z. Kraiem, and D. Melamed. 2002. Impaired light chain allelic exclusion and lack of positive selection in immature B cells expressing incompetent receptor deficient of CD19. J. Immunol. 168: 5596-5604. (Pubitemid 34556140)
    • (2002) Journal of Immunology , vol.168 , Issue.11 , pp. 5596-5604
    • Shivtiel, S.1    Leider, N.2    Sadeh, O.3    Kraiem, Z.4    Melamed, D.5
  • 40
    • 17044372889 scopus 로고    scopus 로고
    • CD19 regulates positive selection and maturation in B lymphopoiesis: Lack of CD19 imposes developmental arrest of immature B cells and consequential stimulation of receptor editing
    • Diamant, E., Z. Keren, and D. Melamed. 2005. CD19 regulates positive selection and maturation in B lymphopoiesis: lack of CD19 imposes developmental arrest of immature B cells and consequential stimulation of receptor editing. Blood 105: 3247-3254.
    • (2005) Blood , vol.105 , pp. 3247-3254
    • Diamant, E.1    Keren, Z.2    Melamed, D.3
  • 41
    • 0030802147 scopus 로고    scopus 로고
    • Self-antigen does not accelerate immature B cell apoptosis, but stimulates receptor editing as a consequence of developmental arrest
    • DOI 10.1073/pnas.94.17.9267
    • Melamed, D., and D. Nemazee. 1997. Self-antigen does not accelerate immature B cell apoptosis, but stimulates receptor editing as a consequence of developmental arrest. Proc. Natl. Acad. Sci. USA 94: 9267-9272. (Pubitemid 27357818)
    • (1997) Proceedings of the National Academy of Sciences of the United States of America , vol.94 , Issue.17 , pp. 9267-9272
    • Melamed, D.1    Nemazee, D.2
  • 42
    • 0034045874 scopus 로고    scopus 로고
    • Receptor selection in B and T lymphocytes
    • DOI 10.1146/annurev.immunol.18.1.19
    • Nemazee, D. 2000. Receptor selection in B and T lymphocytes. Annu. Rev. Immunol. 18: 19-51. (Pubitemid 30365373)
    • (2000) Annual Review of Immunology , vol.18 , pp. 19-51
    • Nemazee, D.1
  • 43
    • 0028118624 scopus 로고
    • Biochemistry of B lymphocyte activation
    • Gold, M. R., and A. L. DeFranco. 1994. Biochemistry of B lymphocyte activation. Adv. Immunol. 55: 221-295. (Pubitemid 24057055)
    • (1994) Advances in Immunology , vol.55 , pp. 221-295
    • Gold, M.R.1    Defranco, A.L.2
  • 45
    • 34248216554 scopus 로고    scopus 로고
    • Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection
    • Verkoczy, L., B. Duong, P. Skog, D. Aït-Azzouzene, K. Puri, J. L. Vela, and D. Nemazee. 2007. Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection. J. Immunol. 178: 6332-6341. (Pubitemid 46717417)
    • (2007) Journal of Immunology , vol.178 , Issue.10 , pp. 6332-6341
    • Verkoczy, L.1    Duong, B.2    Skog, P.3    Ait-Azzouzene, D.4    Puri, K.5    Vela, J.L.6    Nemazee, D.7
  • 46
    • 44049091757 scopus 로고    scopus 로고
    • Foxo1 directly regulates the transcription of recombination-activating genes during B cell development
    • DOI 10.1038/ni.1612, PII NI.1612
    • Amin, R. H., and M. S. Schlissel. 2008. Foxo1 directly regulates the transcription of recombination-activating genes during B cell development. Nat. Immunol. 9: 613-622. (Pubitemid 351712632)
    • (2008) Nature Immunology , vol.9 , Issue.6 , pp. 613-622
    • Amin, R.H.1    Schlissel, M.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.