LXR driven induction of HDL-cholesterol is independent of intestinal cholesterol absorption and ABCA1 protein expression

Lipids

Volumn 49, Issue 1, 2014, Pages 71-83

  Kannisto, Kristina ^a   Gåfvels, Mats ^a,b   Jiang, Zhao Yan ^a,c   Slätis, Katharina ^a   Hu, Xiaoli ^a   Jorns, Carl ^d   Steffensen, Knut R ^a,d   Eggertsen, Gösta ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

ABCA1; ABCG5; ApoAI; Ezetimibe; GW3965; HDL; Intestinal cholesterol absorption; LXR; NPC1L1

Indexed keywords

3 [3 [[2 CHLORO 3 (TRIFLUOROMETHYL)BENZYL](2 DIPHENYLETHYL)AMINO]PROPOXY]PHENYLACETIC ACID; ABC TRANSPORTER A1; ABC TRANSPORTER G5; APOLIPOPROTEIN A1; EZETIMIBE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIVER X RECEPTOR; MESSENGER RNA; PROTEIN; PROTEIN NPC1L1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL LIVER LEVEL; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; INTESTINE ABSORPTION; LIPID ABSORPTION; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION;

MUS;

ANIMALS; ANTICHOLESTEREMIC AGENTS; APOLIPOPROTEIN A-I; ATP BINDING CASSETTE TRANSPORTER 1; ATP-BINDING CASSETTE TRANSPORTERS; AZETIDINES; BENZOATES; BENZYLAMINES; BLOTTING, WESTERN; CELL LINE, TUMOR; CELLS, CULTURED; CHOLESTEROL; CHOLESTEROL, HDL; FECES; GENE EXPRESSION; HEPATOCYTES; INTESTINAL ABSORPTION; INTESTINES; LIPOPROTEINS; LIVER; MALE; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED C57BL; ORPHAN NUCLEAR RECEPTORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84891862000     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/s11745-013-3853-8     Document Type: Article

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