Pharmacological LXR activation reduces presence of SR-B1 in liver membranes contributing to LXR-mediated induction of HDL-cholesterol

Atherosclerosis

Volumn 222, Issue 2, 2012, Pages 382-389

  Grefhorst, Aldo ^a,b   Oosterveer, Maaike H ^a   Brufau, Gemma ^a   Boesjes, Marije ^a   Kuipers, Folkert ^a   Groen, Albert K ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

HDL; Liver X receptor; LXR; Scavenger receptor 1B; SR B1; T0901317; TICE

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER A1; ABC TRANSPORTER G1; ABC TRANSPORTER G5; ABC TRANSPORTER G8; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; MESSENGER RNA; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; SCAVENGER RECEPTOR BI; STEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL METABOLISM; CONTROLLED STUDY; FECES LEVEL; GENE EXPRESSION REGULATION; HORMONE RECEPTOR INTERACTION; LIVER METABOLISM; MALE; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN CONTENT; TREATMENT DURATION; WILD TYPE;

ANIMALS; ATP BINDING CASSETTE TRANSPORTER 1; ATP-BINDING CASSETTE TRANSPORTERS; BILE ACIDS AND SALTS; CELL MEMBRANE; CHOLESTEROL, HDL; DOWN-REGULATION; FECES; HYDROCARBONS, FLUORINATED; LIPOPROTEINS; LIVER; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; ORPHAN NUCLEAR RECEPTORS; PARTICLE SIZE; SCAVENGER RECEPTORS, CLASS B; SULFONAMIDES; TIME FACTORS; UP-REGULATION;

EID: 84861344598     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.02.014     Document Type: Article

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