Akt suppression of TGFb signaling contributes to the maintenance of vascular identity in embryonic stem cell-derived endothelial cells

Stem Cells

Volumn 32, Issue 1, 2014, Pages 177-190

  Israely, Edo ^a   Ginsberg, Michael ^b   Nolan, Daniel ^b   Ding, Bi Sen ^a   James, Daylon ^a,c   Elemento, Olivier ^c   Rafii, Shahin ^a   Rabbany, Sina Y ^a,d  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b Angiocrine Bioscience   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d HOFSTRA UNIVERSITY   (United States)

Author keywords

Akt; Embryonic; Endothelial; SMAD3; Stem

Indexed keywords

PROTEIN KINASE B; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN A;

ANIMAL CELL; ARTICLE; BLOOD VESSEL SHUNT; CELL CULTURE; CELL FATE; CELL FUNCTION; CELL PROTECTION; CELL SURVIVAL; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYONIC STEM CELL; ENDOTHELIUM CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN STABILITY; SIGNAL TRANSDUCTION; STEM CELL EXPANSION; VASCULAR ENDOTHELIUM; AKT; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; DRUG ANTAGONISM; EMBRYONIC; ENDOTHELIAL; METABOLISM; PHYSIOLOGY; SMAD3; STEM;

AKT; EMBRYONIC; ENDOTHELIAL; SMAD3; STEM;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; EMBRYONIC STEM CELLS; ENDOTHELIAL CELLS; MICE; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 84891808126     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1521     Document Type: Article

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