Hematopoietic stem cells express Tie-2 receptor in the murine fetal liver

Blood

Volumn 96, Issue 12, 2000, Pages 3757-3762

  Hsu, H C ^a   Ema, H ^a   Osawa, M ^a   Nakamura, Y ^a   Suda, T ^a   Nakauchi, H ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; INTERLEUKIN 3; MONOCLONAL ANTIBODY; PROTEIN TYROSINE KINASE; STEM CELL FACTOR;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL POPULATION; CHIMERA; CONTROLLED STUDY; EMBRYO; ENDOTHELIUM CELL; FETUS LIVER; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0034551745     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v96.12.3757.h8003757_3757_3762     Document Type: Article

References (37)

1. Ontogeny of the hemopoietic system: Yolk sac origin of in vivo and in vitro colony forming cells in the developing mouse embryo
2. Role of stem cell migration in initiation of mouse fetal liver hemopoiesis
3. A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells
4. Bipotential precursors of B cells and macrophages in murine fetal liver
5. Development of hematopoietic stem cell activity in the mouse embryo
6. Development of T cell precursor activity in the murine fetal liver
7. Competitive in vivo proliferation of fetal and adult haematopoietic cells in lethally irradiated mice
8. The repopulating potential of fetal liver hematopoietic stem cells in mice exceeds that of their adult bone marrow counterparts
9. Evidence of both ontogeny and transplant dose-regulated expansion of hematopoietic stem cells in vivo
10. Relative to adult marrow, fetal liver repopulates nearly 5 times more effectively long-term than short-term
11. Cellular and developmental properties of fetal hematopoietic stem cells
12. In vivo and in vitro stem cell function of c-kit and Sca-1-positive murine hematopoietic cells
13. Long-term repopulating abilities of enriched fetal liver stem cells measured by competitive repopulation
14. Expression of murine CD38 defines a population of long-term reconstituting hematopoietic stem cells
15. In vitro maintenance of highly purified, transplantable hematopoietic stem cells
16. The purification and characterization of fetal liver hematopoietic stem cells
17. A comparison of long-term repopulating hematopoietic stem cells in fetal liver and adult bone marrow from the mouse
18. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell
19. Characterization of the first definitive hematopoietic stem cells in the AGM and liver of the mouse embryo
20. Tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors
21. Molecular cloning and characterization of mouse Tie and Tek receptor tyrosine kinase genes and their expression in hematopoietic stem cells
22. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
23. Requisite role of angiopoietin-1, a ligand for the Tie-2 receptor, during embryonic angiogenesis
24. In vitro hematopoietic and endothelial cell development from cells expressing Tek receptor in murine aorta-gonad-mesonephros region
25. Expression and function of murine receptor tyrosine kinases, Tie and Tek, in hematopoietic stem cells
26. Enrichment and characterization of uncommitted B-cell precursors from fetal liver at day 12 of gestation
27. Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac
28. Expansion of hematopoietic stem cells in the developing liver of a mouse embryo
29. A role for pref-1 and HES-1 in thymocyte development
30. Cellular and molecular characterization of the role of the flk-2/flt-3 receptor tyrosine kinase in hematopoietic stem cells
31. The molecular characterization of the fetal stem cell marker AA4
32. A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit
33. Isolation of angiopoietin-1, a ligand for the Tie2 receptor, by secretion-trap expression cloning
34. The genetic program of hematopoietic stem cells
35. Isolation of putative progenitor endothelial cells for angiogenesis
36. KDR receptor: A key marker defining hematopoietic stem cells
37. In vitro effects of angiopoietins and VEGF on hematopoietic and endothelial cells