Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells

Nature Cell Biology

Volumn 12, Issue 11, 2010, Pages 1046-1056

  Kobayashi, Hideki ^a   Butler, Jason M ^a   O'Donnell, Rebekah ^b   Kobayashi, Mariko ^a   Ding, Bi Sen ^a   Bonner, Bryant ^a   Chiu, Vi K ^a   Nolan, Daniel J ^a   Shido, Koji ^a   Benjamin, Laura ^b   Rafii, Shahin ^a,c  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CD135 ANTIGEN; LEUKOSIALIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; TRANSCRIPTION FACTOR FOXO; VASCULOTROPIN A;

ANIMAL CELL; ARTICLE; BONE MARROW; CELL ACTIVATION; CELL DIFFERENTIATION; CELL LINEAGE; CELL POPULATION; CELL PROLIFERATION; CELL RENEWAL; COLONY FORMING UNIT; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; HEMATOPOIETIC STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; UMBILICAL VEIN; UPREGULATION; VASCULAR ENDOTHELIUM;

ANIMALS; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME ACTIVATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASES; PARACRINE COMMUNICATION; PROTO-ONCOGENE PROTEINS C-AKT; TOR SERINE-THREONINE KINASES; TRANSFORMING GROWTH FACTORS;

MUS;

EID: 78149280740     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb2108     Document Type: Article

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