Strong heterogeneity in mutation rate causes misleading hallmarks of natural selection on indel mutations in the human genome

Molecular Biology and Evolution

Volumn 31, Issue 1, 2014, Pages 23-36

  Kvikstad, Erika M ^a   Duret, Laurent ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

homoplasy; indels; natural selection; sequence evolution

Indexed keywords

ALLELE; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; GENE CONVERSION; GENE FREQUENCY; GENETIC HETEROGENEITY; HOMOPLASY; HUMAN; HUMAN GENOME; INDEL MUTATION; MOLECULAR EVOLUTION; MUTATION RATE; NATURAL SELECTION; NONHUMAN; PHYLOGENY; POLARIZATION; SYSTEMATIC ERROR;

HOMOPLASY; INDELS; NATURAL SELECTION; SEQUENCE EVOLUTION;

EVOLUTION, MOLECULAR; GENE CONVERSION; GENETIC LOCI; GENOME, HUMAN; HUMANS; INDEL MUTATION; MODELS, GENETIC; MUTATION RATE; PHYLOGENY; POLYMORPHISM, SINGLE NUCLEOTIDE; SELECTION, GENETIC;

EID: 84891793973     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/mst185     Document Type: Article

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