Ursodeoxycholic acid but not tauroursodeoxycholic acid inhibits proliferation and differentiation of human subcutaneous adipocytes

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Mališová, Lucia ^a,b   Kováčová, Zuzana ^a,b   Koc, Michal ^a,b   Kračmerová, Jana ^a,b   Štich, Vladimír ^a,b   Rossmeislová, Lenka ^a,b  

^a CHARLES UNIVERSITY   (Czech Republic)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FARNESOID X RECEPTOR; G PROTEIN COUPLED MEMBRANE SURFACE RECEPTOR TGR5; G PROTEIN COUPLED RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TAUROURSODEOXYCHOLIC ACID; TOLL LIKE RECEPTOR 4; TUNICAMYCIN; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID;

ABDOMINAL SUBCUTANEOUS FAT; ADIPOCYTE; ADIPOGENESIS; ARTICLE; ATF4 GENE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLULAR STRESS RESPONSE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNAJC3 GENE; DOWN REGULATION; DRUG TARGETING; EDEM1 GENE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FEMALE; FXR GENE; GENE; GENE EXPRESSION; GLUTEAL SUBCUTANEOUS FAT; HSPA5 GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIPOLYSIS; OBESITY; PROADIPOCYTE; PROTEIN EXPRESSION; SUBCUTANEOUS FAT; TGR5 GENE; XBP1 GENE;

ADIPOCYTES; ADIPOGENESIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOKINES; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; SUBCUTANEOUS FAT; TAUROCHENODEOXYCHOLIC ACID; URSODEOXYCHOLIC ACID;

EID: 84891789535     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0082086     Document Type: Article

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