메뉴 건너뛰기




Volumn 8, Issue 12, 2013, Pages

Carcinoma initiation via Rb tumor suppressor inactivation: A versatile approach to epithelial subtype-dependent cancer initiation in diverse tissues

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; CYTOKERATIN 18; CYTOKERATIN 19; PROTEIN P107; PROTEIN P130;

EID: 84891783286     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080459     Document Type: Article
Times cited : (7)

References (40)
  • 1
    • 0036090767 scopus 로고    scopus 로고
    • Keratin expression in human tissues and neoplasms
    • Chu PG, Weiss LM (2002) Keratin expression in human tissues and neoplasms. Histopathology 40: 403-439.
    • (2002) Histopathology , vol.40 , pp. 403-439
    • Chu, P.G.1    Weiss, L.M.2
  • 2
    • 68849111162 scopus 로고    scopus 로고
    • Toward unraveling the complexity of simple epithelial keratins in human disease
    • Omary MB, Ku NO, Strnad P, Hanada S (2009) Toward unraveling the complexity of simple epithelial keratins in human disease. J Clin Invest 119: 1794-1805.
    • (2009) J Clin Invest , vol.119 , pp. 1794-1805
    • Omary, M.B.1    Ku, N.O.2    Strnad, P.3    Hanada, S.4
  • 3
    • 44149099717 scopus 로고    scopus 로고
    • The human keratins: Biology and pathology
    • Moll R, Divo M, Langbein L (2008) The human keratins: biology and pathology. Histochem Cell Biol 129: 705-733.
    • (2008) Histochem Cell Biol , vol.129 , pp. 705-733
    • Moll, R.1    Divo, M.2    Langbein, L.3
  • 5
    • 0021064832 scopus 로고
    • Intermediate filament protein synthesis in preimplantation murine embryos
    • Oshima RG, Howe WE, Klier FG, Adamson ED, Shevinsky LH (1983) Intermediate filament protein synthesis in preimplantation murine embryos. Dev Biol 99: 447-455.
    • (1983) Dev Biol , vol.99 , pp. 447-455
    • Oshima, R.G.1    Howe, W.E.2    Klier, F.G.3    Adamson, E.D.4    Shevinsky, L.H.5
  • 6
    • 0019312840 scopus 로고
    • Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation
    • Brulet P, Babinet C, Kemler R, Jacob F (1980) Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation. Proc Natl Acad Sci USA 77: 4113-4117.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 4113-4117
    • Brulet, P.1    Babinet, C.2    Kemler, R.3    Jacob, F.4
  • 7
    • 23844528832 scopus 로고    scopus 로고
    • Type II keratins precede type I keratins during early embryonic development
    • Lu H, Hesse M, Peters B, Magin TM (2005) Type II keratins precede type I keratins during early embryonic development. Eur J Cell Biol 84: 709-718.
    • (2005) Eur J Cell Biol , vol.84 , pp. 709-718
    • Lu, H.1    Hesse, M.2    Peters, B.3    Magin, T.M.4
  • 8
    • 78651397689 scopus 로고    scopus 로고
    • Keratins in health and cancer: More than mere epithelial cell markers
    • Karantza V (2011) Keratins in health and cancer: more than mere epithelial cell markers. Oncogene 30: 127-138.
    • (2011) Oncogene , vol.30 , pp. 127-138
    • Karantza, V.1
  • 9
    • 0001510491 scopus 로고    scopus 로고
    • The RB and p53 pathways in cancer
    • Sherr CJ, McCormick F (2002) The RB and p53 pathways in cancer. Cancer Cell 2: 103-112.
    • (2002) Cancer Cell , vol.2 , pp. 103-112
    • Sherr, C.J.1    McCormick, F.2
  • 10
    • 80052296424 scopus 로고    scopus 로고
    • Newly identified aspects of tumor suppression by RB
    • Viatour P, Sage J (2011) Newly identified aspects of tumor suppression by RB. Dis Model Mech 4: 581-585.
    • (2011) Dis Model Mech , vol.4 , pp. 581-585
    • Viatour, P.1    Sage, J.2
  • 11
    • 84870863931 scopus 로고    scopus 로고
    • Retinoblastoma and phosphate and tensin homolog tumor suppressors: Impact on ductal carcinoma in situ progression
    • Knudsen ES, Pajak TF, Qeenan M, McClendon AK, Armon BD, et al. (2012) Retinoblastoma and phosphate and tensin homolog tumor suppressors: impact on ductal carcinoma in situ progression. Journal of the National Cancer Institute 104: 1825-1836.
    • (2012) Journal of the National Cancer Institute , vol.104 , pp. 1825-1836
    • Knudsen, E.S.1    Pajak, T.F.2    Qeenan, M.3    McClendon, A.K.4    Armon, B.D.5
  • 12
    • 35748943534 scopus 로고    scopus 로고
    • Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumors
    • Gauthier ML, Berman HK, Miller C, Kozakeiwicz K, Chew K, et al. (2007) Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumors. Cancer Cell 12: 479-491.
    • (2007) Cancer Cell , vol.12 , pp. 479-491
    • Gauthier, M.L.1    Berman, H.K.2    Miller, C.3    Kozakeiwicz, K.4    Chew, K.5
  • 13
    • 80052842495 scopus 로고    scopus 로고
    • Association of RB/p16-pathway perturbations with DCIS recurrence: Dependence on tumor versus tissue microenvironment
    • Witkiewicz AK, Rivadeneira DB, Ertel A, Kline J, Hyslop T, et al. (2011) Association of RB/p16-pathway perturbations with DCIS recurrence: dependence on tumor versus tissue microenvironment. Am J Pathol 179: 1171-1178.
    • (2011) Am J Pathol , vol.179 , pp. 1171-1178
    • Witkiewicz, A.K.1    Rivadeneira, D.B.2    Ertel, A.3    Kline, J.4    Hyslop, T.5
  • 14
    • 72449154569 scopus 로고    scopus 로고
    • RB has a critical role in mediating the in vivo checkpoint response, mitigating secondary DNA damage and suppressing liver tumorigenesis initiated by aflatoxin B1
    • Reed CA, Mayhew CN, McClendon AK, Yang X, Witkiewicz A, et al. (2009) RB has a critical role in mediating the in vivo checkpoint response, mitigating secondary DNA damage and suppressing liver tumorigenesis initiated by aflatoxin B1. Oncogene 28: 4434-4443.
    • (2009) Oncogene , vol.28 , pp. 4434-4443
    • Reed, C.A.1    Mayhew, C.N.2    McClendon, A.K.3    Yang, X.4    Witkiewicz, A.5
  • 15
    • 50149120366 scopus 로고    scopus 로고
    • Cellular mechanisms of tumour suppression by the retinoblastoma gene
    • Burkhart DL, Sage J (2008) Cellular mechanisms of tumour suppression by the retinoblastoma gene. Nature Reviews Cancer 8: 671-682.
    • (2008) Nature Reviews Cancer , vol.8 , pp. 671-682
    • Burkhart, D.L.1    Sage, J.2
  • 16
    • 78649888666 scopus 로고    scopus 로고
    • The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression
    • Sharma A, Yeow WS, Ertel A, Coleman I, Clegg N, et al. (2010) The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression. J Clin Invest 120: 4478-4492.
    • (2010) J Clin Invest , vol.120 , pp. 4478-4492
    • Sharma, A.1    Yeow, W.S.2    Ertel, A.3    Coleman, I.4    Clegg, N.5
  • 17
    • 0032549001 scopus 로고    scopus 로고
    • Rb interacts with histone deacetylase to repress transcription
    • Luo RX, Postigo AA, Dean DC (1998) Rb interacts with histone deacetylase to repress transcription. Cell 92: 463-473.
    • (1998) Cell , vol.92 , pp. 463-473
    • Luo, R.X.1    Postigo, A.A.2    Dean, D.C.3
  • 19
    • 0033635597 scopus 로고    scopus 로고
    • Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions
    • Dannenberg JH, van Rossum A, Schuijff L, te Riele H (2000) Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions. Genes Dev 14: 3051-3064.
    • (2000) Genes Dev , vol.14 , pp. 3051-3064
    • Dannenberg, J.H.1    Van Rossum, A.2    Schuijff, L.3    Te Riele, H.4
  • 20
    • 0033637086 scopus 로고    scopus 로고
    • Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization
    • Sage J, Mulligan GJ, Attardi LD, Miller A, Chen S, et al. (2000) Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. Genes Dev 14: 3037-3050.
    • (2000) Genes Dev , vol.14 , pp. 3037-3050
    • Sage, J.1    Mulligan, G.J.2    Attardi, L.D.3    Miller, A.4    Chen, S.5
  • 21
    • 0024418207 scopus 로고
    • The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element
    • DeCaprio JA, Ludlow JW, Lynch D, Furukawa Y, Griffin J, et al. (1989) The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell 58: 1085-1095.
    • (1989) Cell , vol.58 , pp. 1085-1095
    • DeCaprio, J.A.1    Ludlow, J.W.2    Lynch, D.3    Furukawa, Y.4    Griffin, J.5
  • 22
    • 0024413538 scopus 로고
    • The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus
    • Dyson N, Buchkovich K, Whyte P, Harlow E (1989) The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus. Cell 58: 249-255.
    • (1989) Cell , vol.58 , pp. 249-255
    • Dyson, N.1    Buchkovich, K.2    Whyte, P.3    Harlow, E.4
  • 23
    • 0024395586 scopus 로고
    • An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110Rb and a second cellular protein, p120
    • Ewen ME, Ludlow JW, Marsilio E, DeCaprio JA, Millikan RC, et al. (1989) An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110Rb and a second cellular protein, p120. Cell 58: 257-267.
    • (1989) Cell , vol.58 , pp. 257-267
    • Ewen, M.E.1    Ludlow, J.W.2    Marsilio, E.3    DeCaprio, J.A.4    Millikan, R.C.5
  • 24
    • 0030794278 scopus 로고    scopus 로고
    • Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen
    • Stubdal H, Zalvide J, Campbell KS, Schweitzer C, Roberts TM, et al. (1997) Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen. Mol Cell Biol 17: 4979-4990.
    • (1997) Mol Cell Biol , vol.17 , pp. 4979-4990
    • Stubdal, H.1    Zalvide, J.2    Campbell, K.S.3    Schweitzer, C.4    Roberts, T.M.5
  • 25
    • 0033929731 scopus 로고    scopus 로고
    • Species-specific elements in the large T-antigen J domain are required for cellular transformation and DNA replication by simian virus 40
    • Sullivan CS, Tremblay JD, Fewell SW, Lewis JA, Brodsky JL, et al. (2000) Species-specific elements in the large T-antigen J domain are required for cellular transformation and DNA replication by simian virus 40. Mol Cell Biol 20: 5749-5757.
    • (2000) Mol Cell Biol , vol.20 , pp. 5749-5757
    • Sullivan, C.S.1    Tremblay, J.D.2    Fewell, S.W.3    Lewis, J.A.4    Brodsky, J.L.5
  • 26
    • 28544436228 scopus 로고    scopus 로고
    • Heterogeneous tumor evolution initiated by loss of pRb function in a preclinical prostate cancer model
    • Hill R, Song Y, Cardiff RD, Van Dyke T (2005) Heterogeneous tumor evolution initiated by loss of pRb function in a preclinical prostate cancer model. Cancer Res 65: 10243-10254.
    • (2005) Cancer Res , vol.65 , pp. 10243-10254
    • Hill, R.1    Song, Y.2    Cardiff, R.D.3    Van Dyke, T.4
  • 27
    • 19344366282 scopus 로고    scopus 로고
    • pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia
    • Simin K, Wu H, Lu L, Pinkel D, Albertson D, et al. (2004) pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia. PLoS Biol 2: E22.
    • (2004) PLoS Biol , vol.2
    • Simin, K.1    Wu, H.2    Lu, L.3    Pinkel, D.4    Albertson, D.5
  • 28
    • 84865140569 scopus 로고    scopus 로고
    • Perturbation of Rb, p53 and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer
    • Szabova L, Yin C, Bupp S, Guerin TM, Schlomer JJ, et al. (2012) Perturbation of Rb, p53 and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer. Cancer Res 72: 13.
    • (2012) Cancer Res , vol.72 , pp. 13
    • Szabova, L.1    Yin, C.2    Bupp, S.3    Guerin, T.M.4    Schlomer, J.J.5
  • 29
    • 0028169994 scopus 로고
    • p53- dependent apoptosis suppresses tumor growth and progression in vivo
    • Symonds H, Krall L, Remington L, Saenz-Robles M, Lowe S, et al. (1994) p53- dependent apoptosis suppresses tumor growth and progression in vivo. Cell 78: 703-711.
    • (1994) Cell , vol.78 , pp. 703-711
    • Symonds, H.1    Krall, L.2    Remington, L.3    Saenz-Robles, M.4    Lowe, S.5
  • 30
    • 0036490954 scopus 로고    scopus 로고
    • Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation
    • Xiao A, Wu H, Pandolfi PP, Louis DN, Van Dyke T (2002) Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation. Cancer Cell 1: 157-168.
    • (2002) Cancer Cell , vol.1 , pp. 157-168
    • Xiao, A.1    Wu, H.2    Pandolfi, P.P.3    Louis, D.N.4    Van Dyke, T.5
  • 32
    • 0026578113 scopus 로고
    • T-antigen mutant activities in vivo: Roles of p53 and pRB binding in tumorigenesis of the choroid plexus
    • Chen J, Tobin GJ, Pipas JM, Van Dyke T (1992) T-antigen mutant activities in vivo: roles of p53 and pRB binding in tumorigenesis of the choroid plexus. Oncogene 7: 1167-1175.
    • (1992) Oncogene , vol.7 , pp. 1167-1175
    • Chen, J.1    Tobin, G.J.2    Pipas, J.M.3    Van Dyke, T.4
  • 34
    • 84870718594 scopus 로고    scopus 로고
    • Cooperativity of Rb, Brca1, and p53 in malignant breast cancer evolution
    • Kumar P, Mukherjee M, Johnson JP, Patel M, Huey B, et al. (2012) Cooperativity of Rb, Brca1, and p53 in malignant breast cancer evolution. PLoS Genet 8: e1003027.
    • (2012) PLoS Genet , vol.8
    • Kumar, P.1    Mukherjee, M.2    Johnson, J.P.3    Patel, M.4    Huey, B.5
  • 35
    • 0020625930 scopus 로고
    • Mutational analysis of simian virus 40 T antigen: Isolation and characterization of mutants with deletions in the Tantigen gene
    • Pipas JM, Peden KW, Nathans D (1983) Mutational analysis of simian virus 40 T antigen: isolation and characterization of mutants with deletions in the Tantigen gene. Mol Cell Biol 3: 203-213.
    • (1983) Mol Cell Biol , vol.3 , pp. 203-213
    • Pipas, J.M.1    Peden, K.W.2    Nathans, D.3
  • 36
    • 0036286620 scopus 로고    scopus 로고
    • T antigens of simian virus 40: Molecular chaperones for viral replication and tumorigenesis
    • Sullivan CS, Pipas JM (2002) T antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesis. Microbiol Mol Biol Rev 66: 179-202.
    • (2002) Microbiol Mol Biol Rev , vol.66 , pp. 179-202
    • Sullivan, C.S.1    Pipas, J.M.2
  • 37
    • 0035487293 scopus 로고    scopus 로고
    • Recombineering: A powerful new tool for mouse functional genomics
    • Copeland NG, Jenkins NA, Court DL (2001) Recombineering: a powerful new tool for mouse functional genomics. Nat Rev Genet 2: 769-779.
    • (2001) Nat Rev Genet , vol.2 , pp. 769-779
    • Copeland, N.G.1    Jenkins, N.A.2    Court, D.L.3
  • 38
    • 0035308590 scopus 로고    scopus 로고
    • A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA
    • Lee EC, Yu D, Martinez de Velasco J, Tessarollo L, Swing DA, et al. (2001) A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. Genomics 73: 56-65.
    • (2001) Genomics , vol.73 , pp. 56-65
    • Lee, E.C.1    Yu, D.2    Martinez De Velasco, J.3    Tessarollo, L.4    Swing, D.A.5
  • 39
    • 0025008962 scopus 로고
    • Distinct positive and negative elements control the limited hepatocyte and choroid plexus expression of transthyretin in transgenic mice
    • Yan C, Costa RH, Darnell JE, Jr., Chen JD, Van Dyke TA (1990) Distinct positive and negative elements control the limited hepatocyte and choroid plexus expression of transthyretin in transgenic mice. EMBO J 9: 869-878.
    • (1990) EMBO J , vol.9 , pp. 869-878
    • Yan, C.1    Costa, R.H.2    Darnell Jr., J.E.3    Chen, J.D.4    Van Dyke, T.A.5
  • 40
    • 47549119127 scopus 로고    scopus 로고
    • A CK19CreERT knockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs
    • Means AL, Xu Y, Zhao A, Ray KC, Gu G (2008) A CK19CreERT knockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs. Genesis 46: 318-323.
    • (2008) Genesis , vol.46 , pp. 318-323
    • Means, A.L.1    Xu, Y.2    Zhao, A.3    Ray, K.C.4    Gu, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.