PH-responsive polymeric micelle based on PEG-poly(β-amino ester)/(amido amine) as intelligent vehicle for magnetic resonance imaging in detection of cerebral ischemic area

Journal of Controlled Release

Volumn 155, Issue 1, 2011, Pages 11-17

  Gao, Guang Hui ^a   Lee, Jae Won ^a,b   Nguyen, Minh Khanh ^a   Im, Geun Ho ^a,b   Yang, Jehoon ^a   Heo, Hyejung ^a   Jeon, Pyoung ^a   Park, Tae Gwan ^c   Lee, Jung Hee ^a   Lee, Doo Sung ^a  

^a Sungkyunkwan University   (South Korea)

^b Samsung Medical Center   (South Korea)

^c Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Contrast agent; Iron oxide nanoparticles; Magnetic resonance imaging; pH responsive; Polymeric micelle

Indexed keywords

ACIDIC ENVIRONMENT; AMINO ESTERS; CEREBRAL ISCHEMIA; CONTRAST AGENT; DIAGNOSTIC IMAGING; HYDROPHOBIC INTERACTIONS; INTELLIGENT CARRIERS; IRON OXIDE NANOPARTICLES; METHOXY POLY(ETHYLENE GLYCOL); MRI SCANNERS; PATHOLOGIC CONDITIONS; PATHOLOGIC TISSUES; PH-RESPONSIVE; PHYSIOLOGICAL PH; POLYMERIC MICELLE; PROTONATED; RAT MODEL; SELF-ASSEMBLED; SUPERCONDUCTING QUANTUM INTERFERENCE DEVICE;

BLOCK COPOLYMERS; DYNAMIC LIGHT SCATTERING; ESTERIFICATION; ESTERS; ETHYLENE; GLYCOLS; HYDROPHOBICITY; INTELLIGENT VEHICLE HIGHWAY SYSTEMS; IRON OXIDES; MICELLES; NANOMAGNETICS; NANOPARTICLES; PATHOLOGY; PH; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYMERS; PROBES; QUANTUM INTERFERENCE DEVICES; RESONANCE; SCANNING; SQUIDS; TISSUE;

MAGNETIC RESONANCE IMAGING;

COPOLYMER; CYTOTOXIC AGENT; DOXORUBICIN; DRUG CARRIER; IRON OXIDE; MACROGOL; METHOXY POLY(ETHYLENE GLYCOL) POLY(BETA AMINO ESTER CO AMIDO AMINE) COPOLYMER; POLY(BETA AMINO ESTER CO AMIDO AMINE); POLYMER; UNCLASSIFIED DRUG;

ACIDITY; ANALYSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ISCHEMIA; CRITICAL MICELLE CONCENTRATION; CYTOTOXICITY; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; LIGHT SCATTERING; MICELLE; NANOENCAPSULATION; NANOPROBE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; SOLUBILITY;

ANIMALS; BRAIN ISCHEMIA; CELL LINE, TUMOR; CONTRAST MEDIA; DELAYED-ACTION PREPARATIONS; FERRIC COMPOUNDS; HUMANS; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE IMAGING; MICELLES; MODELS, MOLECULAR; NANOPARTICLES; POLYETHYLENE GLYCOLS; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 80053334176     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.09.012     Document Type: Article

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