-
1
-
-
0022402513
-
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
-
Greider C.W., Blackburn E.H. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 1985, 43:405-413.
-
(1985)
Cell
, vol.43
, pp. 405-413
-
-
Greider, C.W.1
Blackburn, E.H.2
-
2
-
-
0037148271
-
Telomerase in the human organism
-
Collins K., Mitchell J.R. Telomerase in the human organism. Oncogene 2002, 21:564-579.
-
(2002)
Oncogene
, vol.21
, pp. 564-579
-
-
Collins, K.1
Mitchell, J.R.2
-
3
-
-
0034006777
-
Role of telomerase in cell senescence and oncogenesis
-
Urquidi V., Tarin D., Goodison S. Role of telomerase in cell senescence and oncogenesis. Annu. Rev. Med. 2000, 51:65-79.
-
(2000)
Annu. Rev. Med.
, vol.51
, pp. 65-79
-
-
Urquidi, V.1
Tarin, D.2
Goodison, S.3
-
4
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Kim N.W., Piatyszek M.A., Prowse K.R., Harley C.B., West M.D., Ho P.L., Coviello G.M., Wright W.E., Weinrich S.L., Shay J.W. Specific association of human telomerase activity with immortal cells and cancer. Science 1994, 266:2011-2015.
-
(1994)
Science
, vol.266
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.6
Coviello, G.M.7
Wright, W.E.8
Weinrich, S.L.9
Shay, J.W.10
-
5
-
-
0026523228
-
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
-
Counter C.M., Avilion A.A., LeFeuvre C.E., Stewart N.G., Greider C.W., Harley C.B., Bacchetti S. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 1992, 11:1921-1929.
-
(1992)
EMBO J.
, vol.11
, pp. 1921-1929
-
-
Counter, C.M.1
Avilion, A.A.2
LeFeuvre, C.E.3
Stewart, N.G.4
Greider, C.W.5
Harley, C.B.6
Bacchetti, S.7
-
6
-
-
0035059660
-
Telomerase and cancer
-
Shay J.W., Zou Y., Hiyama E., Wright W.E. Telomerase and cancer. Hum. Mol. Genet. 2001, 10:677-685.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 677-685
-
-
Shay, J.W.1
Zou, Y.2
Hiyama, E.3
Wright, W.E.4
-
7
-
-
17344363008
-
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas
-
Nakayama J., Tahara H., Tahara E., Saito M., Ito K., Nakamura H., Nakanishi T., Ide T., Ishikawa F. Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas. Nat. Genet. 1998, 18:65-68.
-
(1998)
Nat. Genet.
, vol.18
, pp. 65-68
-
-
Nakayama, J.1
Tahara, H.2
Tahara, E.3
Saito, M.4
Ito, K.5
Nakamura, H.6
Nakanishi, T.7
Ide, T.8
Ishikawa, F.9
-
8
-
-
0032440891
-
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization
-
Counter C.M., Hahn W.C., Wei W., Caddle S.D., Beijersbergen R.L., Lansdorp P.M., Sedivy J.M., Weinberg R.A. Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:14723-14728.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 14723-14728
-
-
Counter, C.M.1
Hahn, W.C.2
Wei, W.3
Caddle, S.D.4
Beijersbergen, R.L.5
Lansdorp, P.M.6
Sedivy, J.M.7
Weinberg, R.A.8
-
9
-
-
0031750443
-
Antisense telomerase treatment: induction of two distinct pathways, apoptosis and differentiation
-
Kondo S., Tanaka Y., Kondo Y., Hitomi M., Barnett G.H., Ishizaka Y., Liu J., Haqqi T., Nishiyama A., Villeponteau B., Cowell J.K., Barna B.P. Antisense telomerase treatment: induction of two distinct pathways, apoptosis and differentiation. FASEB J. 1998, 12:801-811.
-
(1998)
FASEB J.
, vol.12
, pp. 801-811
-
-
Kondo, S.1
Tanaka, Y.2
Kondo, Y.3
Hitomi, M.4
Barnett, G.H.5
Ishizaka, Y.6
Liu, J.7
Haqqi, T.8
Nishiyama, A.9
Villeponteau, B.10
Cowell, J.K.11
Barna, B.P.12
-
10
-
-
49749139661
-
Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers
-
Kyo S., Takakura M., Fujiwara T., Inoue M. Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers. Cancer Sci. 2008, 99:1528-1538.
-
(2008)
Cancer Sci.
, vol.99
, pp. 1528-1538
-
-
Kyo, S.1
Takakura, M.2
Fujiwara, T.3
Inoue, M.4
-
11
-
-
0033082526
-
Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells
-
Takakura M., Kyo S., Kanaya T., Hirano H., Takeda J., Yutsudo M., Inoue M. Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells. Cancer Res. 1999, 59:551-557.
-
(1999)
Cancer Res.
, vol.59
, pp. 551-557
-
-
Takakura, M.1
Kyo, S.2
Kanaya, T.3
Hirano, H.4
Takeda, J.5
Yutsudo, M.6
Inoue, M.7
-
12
-
-
0033558281
-
Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene
-
Horikawa I., Cable P.L., Afshari C., Barrett J.C. Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene. Cancer Res. 1999, 59:826-830.
-
(1999)
Cancer Res.
, vol.59
, pp. 826-830
-
-
Horikawa, I.1
Cable, P.L.2
Afshari, C.3
Barrett, J.C.4
-
13
-
-
0033521960
-
Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation
-
Greenberg R.A., O'Hagan R.C., Deng H., Xiao Q., Hann S.R., Adams R.R., Lichtsteiner S., Chin L., Morin G.B., DePinho R.A. Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation. Oncogene 1999, 18:1219-1226.
-
(1999)
Oncogene
, vol.18
, pp. 1219-1226
-
-
Greenberg, R.A.1
O'Hagan, R.C.2
Deng, H.3
Xiao, Q.4
Hann, S.R.5
Adams, R.R.6
Lichtsteiner, S.7
Chin, L.8
Morin, G.B.9
DePinho, R.A.10
-
14
-
-
2642610318
-
Myc activates telomerase
-
Wang J., Xie L.Y., Allan S., Beach D., Hannon G.J. Myc activates telomerase. Genes Dev. 1998, 12:1769-1774.
-
(1998)
Genes Dev.
, vol.12
, pp. 1769-1774
-
-
Wang, J.1
Xie, L.Y.2
Allan, S.3
Beach, D.4
Hannon, G.J.5
-
15
-
-
0032911694
-
Direct activation of TERT transcription by c-MYC
-
Wu K.J., Grandori C., Amacker M., Simon-Vermot N., Polack A., Lingner J., Dalla-Favera R. Direct activation of TERT transcription by c-MYC. Nat. Genet. 1999, 21:220-224.
-
(1999)
Nat. Genet.
, vol.21
, pp. 220-224
-
-
Wu, K.J.1
Grandori, C.2
Amacker, M.3
Simon-Vermot, N.4
Polack, A.5
Lingner, J.6
Dalla-Favera, R.7
-
16
-
-
0035394055
-
E2F-1 represses transcription of the human telomerase reverse transcriptase gene
-
Crowe D.L., Nguyen D.C., Tsang K.J., Kyo S. E2F-1 represses transcription of the human telomerase reverse transcriptase gene. Nucleic Acids Res. 2001, 29:2789-2794.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 2789-2794
-
-
Crowe, D.L.1
Nguyen, D.C.2
Tsang, K.J.3
Kyo, S.4
-
17
-
-
0345549479
-
Regulation of telomerase reverse transcriptase gene activity by upstream stimulatory factor
-
Goueli B.S., Janknecht R. Regulation of telomerase reverse transcriptase gene activity by upstream stimulatory factor. Oncogene 2003, 22:8042-8047.
-
(2003)
Oncogene
, vol.22
, pp. 8042-8047
-
-
Goueli, B.S.1
Janknecht, R.2
-
18
-
-
2942709631
-
Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT)
-
Nishi H., Nakada T., Kyo S., Inoue M., Shay J.W., Isaka K. Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT). Mol. Cell. Biol. 2004, 24:6076-6083.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 6076-6083
-
-
Nishi, H.1
Nakada, T.2
Kyo, S.3
Inoue, M.4
Shay, J.W.5
Isaka, K.6
-
19
-
-
84866551580
-
Human telomerase reverse transcriptase (hTERT) is a novel target of the Wnt/beta-catenin pathway in human cancer
-
Zhang Y., Toh L., Lau P., Wang X. Human telomerase reverse transcriptase (hTERT) is a novel target of the Wnt/beta-catenin pathway in human cancer. J. Biol. Chem. 2012, 287:32494-32511.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 32494-32511
-
-
Zhang, Y.1
Toh, L.2
Lau, P.3
Wang, X.4
-
20
-
-
53449083111
-
Central role of PI3K in transcriptional activation of hTERT in HTLV-I-infected cells
-
Bellon M., Nicot C. Central role of PI3K in transcriptional activation of hTERT in HTLV-I-infected cells. Blood 2008, 112:2946-2955.
-
(2008)
Blood
, vol.112
, pp. 2946-2955
-
-
Bellon, M.1
Nicot, C.2
-
21
-
-
72149106462
-
Transcriptional activation of hTERT, the human telomerase reverse transcriptase, by nuclear factor of activated T cells
-
Chebel A., Rouault J.P., Urbanowicz I., Baseggio L., Chien W.W., Salles G., Ffrench M. Transcriptional activation of hTERT, the human telomerase reverse transcriptase, by nuclear factor of activated T cells. J. Biol. Chem. 2009, 284:35725-35734.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 35725-35734
-
-
Chebel, A.1
Rouault, J.P.2
Urbanowicz, I.3
Baseggio, L.4
Chien, W.W.5
Salles, G.6
Ffrench, M.7
-
22
-
-
79959419265
-
High-mobility group A2 protein modulates hTERT transcription to promote tumorigenesis
-
Li A.Y., Lin H.H., Kuo C.Y., Shih H.M., Wang C.C., Yen Y., Ann D.K. High-mobility group A2 protein modulates hTERT transcription to promote tumorigenesis. Mol. Cell. Biol. 2011, 31:2605-2617.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 2605-2617
-
-
Li, A.Y.1
Lin, H.H.2
Kuo, C.Y.3
Shih, H.M.4
Wang, C.C.5
Yen, Y.6
Ann, D.K.7
-
23
-
-
0037102196
-
The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells
-
Dimri G.P., Martinez J.L., Jacobs J.J., Keblusek P., Itahana K., Van Lohuizen M., Campisi J., Wazer D.E., Band V. The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells. Cancer Res. 2002, 62:4736-4745.
-
(2002)
Cancer Res.
, vol.62
, pp. 4736-4745
-
-
Dimri, G.P.1
Martinez, J.L.2
Jacobs, J.J.3
Keblusek, P.4
Itahana, K.5
Van Lohuizen, M.6
Campisi, J.7
Wazer, D.E.8
Band, V.9
-
24
-
-
0030008177
-
Telomerase activation by the E6 gene product of human papillomavirus type 16
-
Klingelhutz A.J., Foster S.A., McDougall J.K. Telomerase activation by the E6 gene product of human papillomavirus type 16. Nature 1996, 380:79-82.
-
(1996)
Nature
, vol.380
, pp. 79-82
-
-
Klingelhutz, A.J.1
Foster, S.A.2
McDougall, J.K.3
-
25
-
-
0033601234
-
The Wilms' tumor 1 tumor suppressor gene represses transcription of the human telomerase reverse transcriptase gene
-
Oh S., Song Y., Yim J., Kim T.K. The Wilms' tumor 1 tumor suppressor gene represses transcription of the human telomerase reverse transcriptase gene. J. Biol. Chem. 1999, 274:37473-37478.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37473-37478
-
-
Oh, S.1
Song, Y.2
Yim, J.3
Kim, T.K.4
-
26
-
-
0343673898
-
Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1
-
Gunes C., Lichtsteiner S., Vasserot A.P., Englert C. Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1. Cancer Res. 2000, 60:2116-2121.
-
(2000)
Cancer Res.
, vol.60
, pp. 2116-2121
-
-
Gunes, C.1
Lichtsteiner, S.2
Vasserot, A.P.3
Englert, C.4
-
27
-
-
0034234575
-
Identification and characterization of negative regulatory elements of the human telomerase catalytic subunit (hTERT) gene promoter: possible role of MZF-2 in transcriptional repression of hTERT
-
Fujimoto K., Kyo S., Takakura M., Kanaya T., Kitagawa Y., Itoh H., Takahashi M., Inoue M. Identification and characterization of negative regulatory elements of the human telomerase catalytic subunit (hTERT) gene promoter: possible role of MZF-2 in transcriptional repression of hTERT. Nucleic Acids Res. 2000, 28:2557-2562.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 2557-2562
-
-
Fujimoto, K.1
Kyo, S.2
Takakura, M.3
Kanaya, T.4
Kitagawa, Y.5
Itoh, H.6
Takahashi, M.7
Inoue, M.8
-
28
-
-
47949116315
-
NFX1 interacts with mSin3A/histone deacetylase to repress hTERT transcription in keratinocytes
-
Xu M., Luo W., Elzi D.J., Grandori C., Galloway D.A. NFX1 interacts with mSin3A/histone deacetylase to repress hTERT transcription in keratinocytes. Mol. Cell. Biol. 2008, 28:4819-4828.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 4819-4828
-
-
Xu, M.1
Luo, W.2
Elzi, D.J.3
Grandori, C.4
Galloway, D.A.5
-
29
-
-
33748741642
-
Transforming growth factor beta suppresses human telomerase reverse transcriptase (hTERT) by Smad3 interactions with c-Myc and the hTERT gene
-
Li H., Xu D., Li J., Berndt M.C., Liu J.P. Transforming growth factor beta suppresses human telomerase reverse transcriptase (hTERT) by Smad3 interactions with c-Myc and the hTERT gene. J. Biol. Chem. 2006, 281:25588-25600.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 25588-25600
-
-
Li, H.1
Xu, D.2
Li, J.3
Berndt, M.C.4
Liu, J.P.5
-
30
-
-
48749095772
-
Role of menin in the regulation of telomerase activity in normal and cancer cells
-
Hashimoto M., Kyo S., Hua X., Tahara H., Nakajima M., Takakura M., Sakaguchi J., Maida Y., Nakamura M., Ikoma T., Mizumoto Y., Inoue M. Role of menin in the regulation of telomerase activity in normal and cancer cells. Int. J. Oncol. 2008, 33:333-340.
-
(2008)
Int. J. Oncol.
, vol.33
, pp. 333-340
-
-
Hashimoto, M.1
Kyo, S.2
Hua, X.3
Tahara, H.4
Nakajima, M.5
Takakura, M.6
Sakaguchi, J.7
Maida, Y.8
Nakamura, M.9
Ikoma, T.10
Mizumoto, Y.11
Inoue, M.12
-
31
-
-
0034718769
-
Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells
-
Xu D., Wang Q., Gruber A., Bjorkholm M., Chen Z., Zaid A., Selivanova G., Peterson C., Wiman K.G., Pisa P. Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells. Oncogene 2000, 19:5123-5133.
-
(2000)
Oncogene
, vol.19
, pp. 5123-5133
-
-
Xu, D.1
Wang, Q.2
Gruber, A.3
Bjorkholm, M.4
Chen, Z.5
Zaid, A.6
Selivanova, G.7
Peterson, C.8
Wiman, K.G.9
Pisa, P.10
-
32
-
-
0034048726
-
Adenoviral expression of p53 represses telomerase activity through down-regulation of human telomerase reverse transcriptase transcription
-
Kanaya T., Kyo S., Hamada K., Takakura M., Kitagawa Y., Harada H., Inoue M. Adenoviral expression of p53 represses telomerase activity through down-regulation of human telomerase reverse transcriptase transcription. Clin. Cancer. Res. 2000, 6:1239-1247.
-
(2000)
Clin. Cancer. Res.
, vol.6
, pp. 1239-1247
-
-
Kanaya, T.1
Kyo, S.2
Hamada, K.3
Takakura, M.4
Kitagawa, Y.5
Harada, H.6
Inoue, M.7
-
33
-
-
23644460701
-
Hormones and growth factors regulate telomerase activity in ageing and cancer
-
Bayne S., Liu J.P. Hormones and growth factors regulate telomerase activity in ageing and cancer. Mol. Cell. Endocrinol. 2005, 240:11-22.
-
(2005)
Mol. Cell. Endocrinol.
, vol.240
, pp. 11-22
-
-
Bayne, S.1
Liu, J.P.2
-
34
-
-
0034107095
-
Induction of hTERT expression and telomerase activity by estrogens in human ovary epithelium cells
-
Misiti S., Nanni S., Fontemaggi G., Cong Y.S., Wen J., Hirte H.W., Piaggio G., Sacchi A., Pontecorvi A., Bacchetti S., Farsetti A. Induction of hTERT expression and telomerase activity by estrogens in human ovary epithelium cells. Mol. Cell. Biol. 2000, 20:3764-3771.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3764-3771
-
-
Misiti, S.1
Nanni, S.2
Fontemaggi, G.3
Cong, Y.S.4
Wen, J.5
Hirte, H.W.6
Piaggio, G.7
Sacchi, A.8
Pontecorvi, A.9
Bacchetti, S.10
Farsetti, A.11
-
35
-
-
59249103923
-
Regulation of telomerase activity by interferon regulatory factors 4 and 8 in immune cells
-
Hrdlickova R., Nehyba J., Bose H.R. Regulation of telomerase activity by interferon regulatory factors 4 and 8 in immune cells. Mol. Cell. Biol. 2009, 29:929-941.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 929-941
-
-
Hrdlickova, R.1
Nehyba, J.2
Bose, H.R.3
-
36
-
-
0036884618
-
Opposing regulatory roles of E2F in human telomerase reverse transcriptase (hTERT) gene expression in human tumor and normal somatic cells
-
Won J., Yim J., Kim T.K. Opposing regulatory roles of E2F in human telomerase reverse transcriptase (hTERT) gene expression in human tumor and normal somatic cells. FASEB J. 2002, 16:1943-1945.
-
(2002)
FASEB J.
, vol.16
, pp. 1943-1945
-
-
Won, J.1
Yim, J.2
Kim, T.K.3
-
37
-
-
0036782079
-
Hypermethylation of the human telomerase catalytic subunit (hTERT) gene correlates with telomerase activity
-
Guilleret I., Yan P., Grange F., Braunschweig R., Bosman F.T., Benhattar J. Hypermethylation of the human telomerase catalytic subunit (hTERT) gene correlates with telomerase activity. Int. J. Cancer 2002, 101:335-341.
-
(2002)
Int. J. Cancer
, vol.101
, pp. 335-341
-
-
Guilleret, I.1
Yan, P.2
Grange, F.3
Braunschweig, R.4
Bosman, F.T.5
Benhattar, J.6
-
38
-
-
0034680840
-
Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells
-
Cong Y.S., Bacchetti S. Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells. J. Biol. Chem. 2000, 275:35665-35668.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35665-35668
-
-
Cong, Y.S.1
Bacchetti, S.2
-
39
-
-
0032079716
-
The 58-kDa microspherule protein (MSP58), a nucleolar protein, interacts with nucleolar protein p120
-
Ren Y., Busch R.K., Perlaky L., Busch H. The 58-kDa microspherule protein (MSP58), a nucleolar protein, interacts with nucleolar protein p120. Eur. J. Biochem. 1998, 253:734-742.
-
(1998)
Eur. J. Biochem.
, vol.253
, pp. 734-742
-
-
Ren, Y.1
Busch, R.K.2
Perlaky, L.3
Busch, H.4
-
40
-
-
0037067668
-
Essential role of the 58-kDa microspherule protein in the modulation of Daxx-dependent transcriptional repression as revealed by nucleolar sequestration
-
Lin D.Y., Shih H.M. Essential role of the 58-kDa microspherule protein in the modulation of Daxx-dependent transcriptional repression as revealed by nucleolar sequestration. J. Biol. Chem. 2002, 277:25446-25456.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25446-25456
-
-
Lin, D.Y.1
Shih, H.M.2
-
41
-
-
15044365234
-
Association, mutual stabilization, and transcriptional activity of the STRA13 and MSP58 proteins
-
Ivanova A.V., Ivanov S.V., Lerman M.L. Association, mutual stabilization, and transcriptional activity of the STRA13 and MSP58 proteins. Cell. Mol. Life Sci. 2005, 62:471-484.
-
(2005)
Cell. Mol. Life Sci.
, vol.62
, pp. 471-484
-
-
Ivanova, A.V.1
Ivanov, S.V.2
Lerman, M.L.3
-
42
-
-
28244475343
-
Microspherule protein 1, Mi-2beta, and RET finger protein associate in the nucleolus and up-regulate ribosomal gene transcription
-
Shimono K., Shimono Y., Shimokata K., Ishiguro N., Takahashi M. Microspherule protein 1, Mi-2beta, and RET finger protein associate in the nucleolus and up-regulate ribosomal gene transcription. J. Biol. Chem. 2005, 280:39436-39447.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 39436-39447
-
-
Shimono, K.1
Shimono, Y.2
Shimokata, K.3
Ishiguro, N.4
Takahashi, M.5
-
43
-
-
1642338831
-
Human MCRS2, a cell-cycle-dependent protein, associates with LPTS/PinX1 and reduces the telomere length
-
Song H., Li Y., Chen G., Xing Z., Zhao J., Yokoyama K.K., Li T., Zhao M. Human MCRS2, a cell-cycle-dependent protein, associates with LPTS/PinX1 and reduces the telomere length. Biochem. Biophys. Res. Commun. 2004, 316:1116-1123.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.316
, pp. 1116-1123
-
-
Song, H.1
Li, Y.2
Chen, G.3
Xing, Z.4
Zhao, J.5
Yokoyama, K.K.6
Li, T.7
Zhao, M.8
-
44
-
-
77956699130
-
Drosophila MCRS2 associates with RNA polymerase II complexes to regulate transcription
-
Andersen D.S., Raja S.J., Colombani J., Shaw R.L., Langton P.F., Akhtar A., Tapon N. Drosophila MCRS2 associates with RNA polymerase II complexes to regulate transcription. Mol. Cell. Biol. 2010, 30:4744-4755.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 4744-4755
-
-
Andersen, D.S.1
Raja, S.J.2
Colombani, J.3
Shaw, R.L.4
Langton, P.F.5
Akhtar, A.6
Tapon, N.7
-
45
-
-
77955474748
-
The nonspecific lethal complex is a transcriptional regulator in Drosophila
-
Raja S.J., Charapitsa I., Conrad T., Vaquerizas J.M., Gebhardt P., Holz H., Kadlec J., Fraterman S., Luscombe N.M., Akhtar A. The nonspecific lethal complex is a transcriptional regulator in Drosophila. Mol. Cell 2010, 38:827-841.
-
(2010)
Mol. Cell
, vol.38
, pp. 827-841
-
-
Raja, S.J.1
Charapitsa, I.2
Conrad, T.3
Vaquerizas, J.M.4
Gebhardt, P.5
Holz, H.6
Kadlec, J.7
Fraterman, S.8
Luscombe, N.M.9
Akhtar, A.10
-
46
-
-
79953170957
-
Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling
-
Chen L., Cai Y., Jin J., Florens L., Swanson S.K., Washburn M.P., Conaway J.W., Conaway R.C. Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling. J. Biol. Chem. 2011, 286:11283-11289.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 11283-11289
-
-
Chen, L.1
Cai, Y.2
Jin, J.3
Florens, L.4
Swanson, S.K.5
Washburn, M.P.6
Conaway, J.W.7
Conaway, R.C.8
-
47
-
-
77951182263
-
Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex
-
Cai Y., Jin J., Swanson S.K., Cole M.D., Choi S.H., Florens L., Washburn M.P., Conaway J.W., Conaway R.C. Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex. J. Biol. Chem. 2010, 285:4268-4272.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 4268-4272
-
-
Cai, Y.1
Jin, J.2
Swanson, S.K.3
Cole, M.D.4
Choi, S.H.5
Florens, L.6
Washburn, M.P.7
Conaway, J.W.8
Conaway, R.C.9
-
48
-
-
84863308674
-
58-kDa microspherule protein (MSP58) is novel Brahma-related gene 1 (BRG1)-associated protein that modulates p53/p21 senescence pathway
-
Hsu C.C., Lee Y.C., Yeh S.H., Chen C.H., Wu C.C., Wang T.Y., Chen Y.N., Hung L.Y., Liu Y.W., Chen H.K., Hsiao Y.T., Wang W.S., Tsou J.H., Tsou Y.H., Wu M.H., Chang W.C., Lin D.Y. 58-kDa microspherule protein (MSP58) is novel Brahma-related gene 1 (BRG1)-associated protein that modulates p53/p21 senescence pathway. J. Biol. Chem. 2012, 287:22533-22548.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 22533-22548
-
-
Hsu, C.C.1
Lee, Y.C.2
Yeh, S.H.3
Chen, C.H.4
Wu, C.C.5
Wang, T.Y.6
Chen, Y.N.7
Hung, L.Y.8
Liu, Y.W.9
Chen, H.K.10
Hsiao, Y.T.11
Wang, W.S.12
Tsou, J.H.13
Tsou, Y.H.14
Wu, M.H.15
Chang, W.C.16
Lin, D.Y.17
-
49
-
-
33746911579
-
P78/MCRS1 forms a complex with centrosomal protein Nde1 and is essential for cell viability
-
Hirohashi Y., Wang Q., Liu Q., Du X., Zhang H., Sato N., Greene M.I. p78/MCRS1 forms a complex with centrosomal protein Nde1 and is essential for cell viability. Oncogene 2006, 25:4937-4946.
-
(2006)
Oncogene
, vol.25
, pp. 4937-4946
-
-
Hirohashi, Y.1
Wang, Q.2
Liu, Q.3
Du, X.4
Zhang, H.5
Sato, N.6
Greene, M.I.7
-
50
-
-
33750513797
-
DIPA, which can localize to the centrosome, associates with p78/MCRS1/MSP58 and acts as a repressor of gene transcription
-
Du X., Wang Q., Hirohashi Y., Greene M.I. DIPA, which can localize to the centrosome, associates with p78/MCRS1/MSP58 and acts as a repressor of gene transcription. Exp. Mol. Pathol. 2006, 81:184-190.
-
(2006)
Exp. Mol. Pathol.
, vol.81
, pp. 184-190
-
-
Du, X.1
Wang, Q.2
Hirohashi, Y.3
Greene, M.I.4
-
51
-
-
0035829741
-
TOJ3, a target of the v-Jun transcription factor, encodes a protein with transforming activity related to human microspherule protein 1 (MCRS1)
-
Bader A.G., Schneider M.L., Bister K., Hartl M. TOJ3, a target of the v-Jun transcription factor, encodes a protein with transforming activity related to human microspherule protein 1 (MCRS1). Oncogene 2001, 20:7524-7535.
-
(2001)
Oncogene
, vol.20
, pp. 7524-7535
-
-
Bader, A.G.1
Schneider, M.L.2
Bister, K.3
Hartl, M.4
-
52
-
-
14544282456
-
Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor
-
Okumura K., Zhao M., Depinho R.A., Furnari F.B., Cavenee W.K. Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:2703-2706.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 2703-2706
-
-
Okumura, K.1
Zhao, M.2
Depinho, R.A.3
Furnari, F.B.4
Cavenee, W.K.5
-
53
-
-
14344259439
-
Molecular cloning and characterization of a human gene involved in transcriptional regulation of hTERT
-
Tang Z., Zhao Y., Mei F., Yang S., Li X., Lv J., Hou L., Zhang B. Molecular cloning and characterization of a human gene involved in transcriptional regulation of hTERT. Biochem. Biophys. Res. Commun. 2004, 324:1324-1332.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.324
, pp. 1324-1332
-
-
Tang, Z.1
Zhao, Y.2
Mei, F.3
Yang, S.4
Li, X.5
Lv, J.6
Hou, L.7
Zhang, B.8
-
54
-
-
26944463475
-
Expression of a telomerase-associated gene in normal, atrophic, and tumorous testes
-
Mei F., Zhang B., Tang Z.W., Hou L. Expression of a telomerase-associated gene in normal, atrophic, and tumorous testes. Chin. Med. Sci. J. 2005, 20:217-220.
-
(2005)
Chin. Med. Sci. J.
, vol.20
, pp. 217-220
-
-
Mei, F.1
Zhang, B.2
Tang, Z.W.3
Hou, L.4
-
55
-
-
33645457460
-
Transcriptionally mediated inhibition of telomerase of fungal immunomodulatory protein from Ganoderma tsugae in A549 human lung adenocarcinoma cell line
-
Liao C.H., Hsiao Y.M., Hsu C.P., Lin M.Y., Wang J.C., Huang Y.L., Ko J.L. Transcriptionally mediated inhibition of telomerase of fungal immunomodulatory protein from Ganoderma tsugae in A549 human lung adenocarcinoma cell line. Mol. Carcinog. 2006, 45:220-229.
-
(2006)
Mol. Carcinog.
, vol.45
, pp. 220-229
-
-
Liao, C.H.1
Hsiao, Y.M.2
Hsu, C.P.3
Lin, M.Y.4
Wang, J.C.5
Huang, Y.L.6
Ko, J.L.7
-
56
-
-
10044264506
-
Negative modulation of androgen receptor transcriptional activity by Daxx
-
Lin D.Y., Fang H.I., Ma A.H., Huang Y.S., Pu Y.S., Jenster G., Kung H.J., Shih H.M. Negative modulation of androgen receptor transcriptional activity by Daxx. Mol. Cell. Biol. 2004, 24:10529-10541.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 10529-10541
-
-
Lin, D.Y.1
Fang, H.I.2
Ma, A.H.3
Huang, Y.S.4
Pu, Y.S.5
Jenster, G.6
Kung, H.J.7
Shih, H.M.8
-
57
-
-
0029023065
-
Modifications of a telomeric repeat amplification protocol (TRAP) result in increased reliability, linearity and sensitivity
-
Wright W.E., Shay J.W., Piatyszek M.A. Modifications of a telomeric repeat amplification protocol (TRAP) result in increased reliability, linearity and sensitivity. Nucleic Acids Res. 1995, 23:3794-3795.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 3794-3795
-
-
Wright, W.E.1
Shay, J.W.2
Piatyszek, M.A.3
-
58
-
-
0032004602
-
Increased sensitivity and reproducibility of TRAP assay by avoiding direct primers interaction
-
Falchetti M.L., Levi A., Molinari P., Verna R., D'Ambrosio E. Increased sensitivity and reproducibility of TRAP assay by avoiding direct primers interaction. Nucleic Acids Res. 1998, 26:862-863.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 862-863
-
-
Falchetti, M.L.1
Levi, A.2
Molinari, P.3
Verna, R.4
D'Ambrosio, E.5
-
59
-
-
0036711651
-
Subnuclear shuttling of human telomerase induced by transformation and DNA damage
-
Wong J.M., Kusdra L., Collins K. Subnuclear shuttling of human telomerase induced by transformation and DNA damage. Nat. Cell Biol. 2002, 4:731-736.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 731-736
-
-
Wong, J.M.1
Kusdra, L.2
Collins, K.3
-
60
-
-
0033568462
-
Telomere shortening and apoptosis in telomerase-inhibited human tumor cells
-
Zhang X., Mar V., Zhou W., Harrington L., Robinson M.O. Telomere shortening and apoptosis in telomerase-inhibited human tumor cells. Genes Dev. 1999, 13:2388-2399.
-
(1999)
Genes Dev.
, vol.13
, pp. 2388-2399
-
-
Zhang, X.1
Mar, V.2
Zhou, W.3
Harrington, L.4
Robinson, M.O.5
-
61
-
-
0032828652
-
Inhibition of telomerase limits the growth of human cancer cells
-
Hahn W.C., Stewart S.A., Brooks M.W., York S.G., Eaton E., Kurachi A., Beijersbergen R.L., Knoll J.H., Meyerson M., Weinberg R.A. Inhibition of telomerase limits the growth of human cancer cells. Nat. Med. 1999, 5:1164-1170.
-
(1999)
Nat. Med.
, vol.5
, pp. 1164-1170
-
-
Hahn, W.C.1
Stewart, S.A.2
Brooks, M.W.3
York, S.G.4
Eaton, E.5
Kurachi, A.6
Beijersbergen, R.L.7
Knoll, J.H.8
Meyerson, M.9
Weinberg, R.A.10
-
62
-
-
19944362494
-
P53-Dependent down-regulation of telomerase is mediated by p21waf1
-
Shats I., Milyavsky M., Tang X., Stambolsky P., Erez N., Brosh R., Kogan I., Braunstein I., Tzukerman M., Ginsberg D., Rotter V. p53-Dependent down-regulation of telomerase is mediated by p21waf1. J. Biol. Chem. 2004, 279:50976-50985.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 50976-50985
-
-
Shats, I.1
Milyavsky, M.2
Tang, X.3
Stambolsky, P.4
Erez, N.5
Brosh, R.6
Kogan, I.7
Braunstein, I.8
Tzukerman, M.9
Ginsberg, D.10
Rotter, V.11
-
63
-
-
0028060515
-
The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest
-
Dunaief J.L., Strober B.E., Guha S., Khavari P.A., Alin K., Luban J., Begemann M., Crabtree G.R., Goff S.P. The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell 1994, 79:119-130.
-
(1994)
Cell
, vol.79
, pp. 119-130
-
-
Dunaief, J.L.1
Strober, B.E.2
Guha, S.3
Khavari, P.A.4
Alin, K.5
Luban, J.6
Begemann, M.7
Crabtree, G.R.8
Goff, S.P.9
-
64
-
-
0034737290
-
Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF
-
Zhang H.S., Gavin M., Dahiya A., Postigo A.A., Ma D., Luo R.X., Harbour J.W., Dean D.C. Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. Cell 2000, 101:79-89.
-
(2000)
Cell
, vol.101
, pp. 79-89
-
-
Zhang, H.S.1
Gavin, M.2
Dahiya, A.3
Postigo, A.A.4
Ma, D.5
Luo, R.X.6
Harbour, J.W.7
Dean, D.C.8
-
65
-
-
41649122040
-
Brm transactivates the telomerase reverse transcriptase (TERT) gene and modulates the splicing patterns of its transcripts in concert with p54(nrb)
-
Ito T., Watanabe H., Yamamichi N., Kondo S., Tando T., Haraguchi T., Mizutani T., Sakurai K., Fujita S., Izumi T., Isobe T., Iba H. Brm transactivates the telomerase reverse transcriptase (TERT) gene and modulates the splicing patterns of its transcripts in concert with p54(nrb). Biochem. J. 2008, 411:201-209.
-
(2008)
Biochem. J.
, vol.411
, pp. 201-209
-
-
Ito, T.1
Watanabe, H.2
Yamamichi, N.3
Kondo, S.4
Tando, T.5
Haraguchi, T.6
Mizutani, T.7
Sakurai, K.8
Fujita, S.9
Izumi, T.10
Isobe, T.11
Iba, H.12
-
66
-
-
84872424747
-
Analysis of 20 genes at chromosome band 12q13: RACGAP1 and MCRS1 overexpression in nonsmall-cell lung cancer
-
Liang Y., Liu M., Wang P., Ding X., Cao Y. Analysis of 20 genes at chromosome band 12q13: RACGAP1 and MCRS1 overexpression in nonsmall-cell lung cancer. Genes Chromosomes Cancer 2013, 52:305-315.
-
(2013)
Genes Chromosomes Cancer
, vol.52
, pp. 305-315
-
-
Liang, Y.1
Liu, M.2
Wang, P.3
Ding, X.4
Cao, Y.5
-
67
-
-
84868541264
-
The novel interaction between microspherule protein Msp58 and ubiquitin E3 ligase EDD regulates cell cycle progression
-
Benavides M., Chow-Tsang L.F., Zhang J., Zhong H. The novel interaction between microspherule protein Msp58 and ubiquitin E3 ligase EDD regulates cell cycle progression. Biochim. Biophys. Acta 2013, 1833:21-32.
-
(2013)
Biochim. Biophys. Acta
, vol.1833
, pp. 21-32
-
-
Benavides, M.1
Chow-Tsang, L.F.2
Zhang, J.3
Zhong, H.4
-
68
-
-
84856196744
-
K-fibre minus ends are stabilized by a RanGTP-dependent mechanism essential for functional spindle assembly
-
Meunier S., Vernos I. K-fibre minus ends are stabilized by a RanGTP-dependent mechanism essential for functional spindle assembly. Nat. Cell Biol. 2011, 13:1406-1414.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 1406-1414
-
-
Meunier, S.1
Vernos, I.2
-
69
-
-
20744450967
-
Transcriptional upregulation of DNA polymerase beta by TEIF
-
Zhao Y., Zheng J., Ling Y., Hou L., Zhang B. Transcriptional upregulation of DNA polymerase beta by TEIF. Biochem. Biophys. Res. Commun. 2005, 333:908-916.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.333
, pp. 908-916
-
-
Zhao, Y.1
Zheng, J.2
Ling, Y.3
Hou, L.4
Zhang, B.5
-
70
-
-
63449104484
-
Localization of TEIF in the centrosome and its functional association with centrosome amplification in DNA damage, telomere dysfunction and human cancers
-
Gong Y., Sun Y., McNutt M.A., Sun Q., Hou L., Liu H., Shen Q., Ling Y., Chi Y., Zhang B. Localization of TEIF in the centrosome and its functional association with centrosome amplification in DNA damage, telomere dysfunction and human cancers. Oncogene 2009, 28:1549-1560.
-
(2009)
Oncogene
, vol.28
, pp. 1549-1560
-
-
Gong, Y.1
Sun, Y.2
McNutt, M.A.3
Sun, Q.4
Hou, L.5
Liu, H.6
Shen, Q.7
Ling, Y.8
Chi, Y.9
Zhang, B.10
-
71
-
-
0037288474
-
Chromosome instability in cancer: how, when, and why?
-
Gisselsson D. Chromosome instability in cancer: how, when, and why?. Adv. Cancer Res. 2003, 87:1-29.
-
(2003)
Adv. Cancer Res.
, vol.87
, pp. 1-29
-
-
Gisselsson, D.1
-
72
-
-
33846601331
-
Expression of TEIF protein in soft tissue tumors and its significance
-
Gong Y.L., Li T., Guo H., Sun Y., Chi Y.K., Ling Y., Shen Q., Liu H.J., Hou L., Zhang B. Expression of TEIF protein in soft tissue tumors and its significance. Zhonghua Bing Li Xue Za Zhi 2006, 35:651-655.
-
(2006)
Zhonghua Bing Li Xue Za Zhi
, vol.35
, pp. 651-655
-
-
Gong, Y.L.1
Li, T.2
Guo, H.3
Sun, Y.4
Chi, Y.K.5
Ling, Y.6
Shen, Q.7
Liu, H.J.8
Hou, L.9
Zhang, B.10
-
73
-
-
80051919381
-
Expression of TEIF protein in colorectal tumors and its correlation with centrosome abnormality
-
Gao Y., Zhang B. Expression of TEIF protein in colorectal tumors and its correlation with centrosome abnormality. Ai Zheng 2009, 28:1277-1282.
-
(2009)
Ai Zheng
, vol.28
, pp. 1277-1282
-
-
Gao, Y.1
Zhang, B.2
|