Inhibition of tumor necrosis factor-alpha and cyclooxigenase-2 by Isatin: A molecular mechanism of protection against TNBS-induced colitis in rats

Chemico-Biological Interactions

Volumn 209, Issue 1, 2014, Pages 48-55

  Rabelo Socca, Eduardo Augusto ^a   Luiz Ferreira, Anderson ^b   De Faria, Felipe Meira ^a   De Almeida, Ana Cristina ^a   Dunder, Ricardo José ^a   Manzo, Luis Paulo ^a   Souza Brito, Alba Regina Monteiro ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b FEDERAL UNIVERSITY OF GOIÁS   (Brazil)

Author keywords

COX 2; Isatin; Myeloperoxidase; TNBS; TNF ; Ulcerative colitis

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GAMMA INTERFERON; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; INTERLEUKIN 10; ISATIN; MYELOPEROXIDASE; PROSTAGLANDIN E2; SUPEROXIDE DISMUTASE; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; COLITIS; CONTROLLED STUDY; DIARRHEA; DRUG DOSE COMPARISON; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; TISSUE ADHESION; WEIGHT CHANGE;

COX-2; ISATIN; MYELOPEROXIDASE; TNBS; TNF-Α; ULCERATIVE COLITIS;

ANIMALS; BLOTTING, WESTERN; COLITIS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; GLUTATHIONE; ISATIN; RATS; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84891681369     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2013.11.019     Document Type: Article

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