Functional diversity of Nocardia in metabolism

Environmental Microbiology

Volumn 16, Issue 1, 2014, Pages 29-48

  Luo, Quan ^a   Hiessl, Sebastian ^a   Steinbüchel, Alexander ^a,b  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

ACTINOBACTERIA; ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); NOCARDIA; POSIBACTERIA;

BIOLOGICAL FACTOR;

ANIMAL; BIOREMEDIATION; CHEMISTRY; CLASSIFICATION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; NOCARDIA; NOCARDIOSIS; PHYLOGENY; REVIEW;

ANIMALS; BIODEGRADATION, ENVIRONMENTAL; BIOLOGICAL FACTORS; HUMANS; NOCARDIA; NOCARDIA INFECTIONS; PHYLOGENY;

EID: 84891635104     PISSN: 14622912     EISSN: 14622920     Source Type: Journal    
DOI: 10.1111/1462-2920.12221     Document Type: Review

References (196)

1. Albuquerque de Barros, E.V., Manfio, G.P., Ribiero Maitan, V., Mendes Bataus, L.A., Kim, S.B., Maldonado, L.A., and Goodfellow, M. (2003) Nocardia cerradoensis sp. nov., a novel isolate from Cerrado soil in Brazil. Int J Syst Evol Microbiol 53: 29-33.
2. Almatawah, Q.A., Cramp, R., and Cowan, D.A. (1999) Characterization of an inducible nitrilase from a thermophilic bacillus. Extremophiles 3: 283-291.
3. Alvarez, H.M., Souto, M.F., Viale, A., and Pucci, O.H. (2001) Biosynthesis of fatty acids and triacylglycerols by 2, 6, 10, 14-tetramethyl pentadecane-grown cells of Nocardia globerula 432. FEMS Microbiol Lett 200: 195-200.
4. Ambrosioni, J., Lew, D., and Garbino, J. (2010) Nocardiosis: updated clinical review and experience at a tertiary center. Infection 38: 89-97.
5. Aoki, H., Sakai, H., Kohsaka, M., Konomi, T., Hosoda, J., Kubochi, Y., etal. (1976) Nocardicin A, a new monocyclic β-lactam antibiotic. I. Discovery, isolation and characterization. J Antibiot (Tokyo) 29: 492-500.
6. Barker, G.A., and Ellory, J.C. (1990) The identification of neutral amino acid transport systems. Exp Physiol 75: 3-26.
7. Bendinger, B., Rijnaarts, H.H., Altendorf, K., and Zehnder, A.J. (1993) Physicochemical cell surface and adhesive properties of coryneform bacteria related to the presence and chain length of mycolic acids. Appl Environ Microbiol 59: 3973-3977.
8. Berekaa, M.M. (2006) Colonization and microbial degradation of polyisoprene rubber by nocardiaform actinomycete Nocardia sp. strain-MBR. Biotechnology 5: 234-239.
9. Betrán, A., Rezusta, A., Lezcano, M.A., Villuendas, M.C., Revillo, M.J., Boiron, P., and Rodríguez-Nava, V. (2009) First Spanish case of nocardiosis caused by Nocardia takedensis. J Clin Microbiol 47: 1918-1919.
10. Bhalla, T.C., and Kumar, H. (2005) Nocardia globerula NHB-2: a versatile nitrile-degrading organism. Can J Microbiol 51: 705-708.
11. Bhatia, M., and Singh, H.D. (1996) Biodegradation of commercial linear alkyl benzenes by Nocardia amarae. J Biosci 21: 487-496.
12. Brown-Elliott, B.A., Brown, J.M., Conville, P.S., and Wallace, R.J., Jr (2006) Clinical and laboratory features of the Nocardia spp. based on current molecular taxonomy. Clin Microbiol Rev 19: 259-282.
13. 1. J Am Chem Soc 106: 784-787.
14. Cane, D.E., and Yang, C.C. (1985) Nargenicin biosynthesis: late stage oxidations and absolute configuration. J Antibiot (Tokyo) 38: 423-426.
15. Celmer, W.D., Cullen, W.P., Moppett, C.E., Jefferson, M.T., Huang, L.H., Shibakawa, R., and Tone, J. (1977) Antibiotics produced by new species of Nocardia. U. S. Patent 4, 148, 883.
16. Celmer, W.D., Chmurny, G.N., Moppett, C.E., Ware, R.S., Watts, P.C., and Whipple, E.B. (1980) Structure of natural antibiotic CP-47, 444. J Am Chem Soc 102: 4203-4209.
17. Cerniglia, C.E. (1992) Biodegradation of polycyclic aromatic hydrocarbons. Biodegradation 3: 351-368.
18. Chamoiseau, G., and Asselineau, J. (1970) Examen des lipides d'une souche de Nocardia farcinica: présence d'acides mycoliques. C R Acad Sci Hebd Seances Acad Sci D 270: 2603-2604.
19. Chang, J.H., Rhee, S.K., Chang, Y.K., and Chang, H.N. (1998) Desulfurization of diesel oils by a newly isolated dibenzothiophene-degrading Nocardia sp. strain CYKS2. Biotechnol Prog 14: 851-855.
20. Chiba, K., Hoshino, Y., Ishino, K., Kogure, T., Mikami, Y., Uehara, Y., and Ishikawa, J. (2007) Construction of a pair of practical Nocardia-Escherichia coli shuttle vectors. Jpn J Infect Dis 60: 45-47.
21. Chun, J., and Goodfellow, M. (1995) A phylogenetic analysis of the genus Nocardia with 16S rRNA gene sequences. Int J Syst Bacteriol 45: 240-245.
22. Cloud, J.L., Conville, P.S., Croft, A., Harmsen, D., Witebsky, F.G., and Carroll, K.C. (2004) Evaluation of partial 16S ribosomal DNA sequencing for identification of Nocardia species by using the MicroSeq 500 system with an expanded database. J Clin Microbiol 42: 578-584.
23. Collins, P.A., and Knowles, C.J. (1983) The utilization of nitriles and amides by Nocardia rhodochrous. J Gen Microbiol 129: 711-718.
24. Conville, P.S., Fischer, S.H., Cartwright, C.P., and Witebsky, F.G. (2000) Identification of Nocardia species by restriction endonuclease analysis of an amplified portion of the 16S rRNA gene. J Clin Microbiol 38: 158-164.
25. Cripps, R.E. (1975) The microbial metabolism of acetophenone. Metabolism of acetophenone and some chloroacetophenones by an Arthrobacter species. Biochem J 152: 233-241.
26. Cripps, R.E., Trudgill, P.W., and Whateley, J.G. (1978) The metabolism of 1-phenylethanol and acetophenone by Nocardia T5 and an Arthrobacter species. Eur J Biochem 86: 175-186.
27. Davidsen, J.M., and Townsend, C.A. (2009) Identification and characterization of NocR as a positive transcriptional regulator of the β-lactam nocardicin A in Nocardia uniformis. J Bacteriol 191: 1066-1077.
28. Davidsen, J.M., and Townsend, C.A. (2012) In vivo characterization of nonribosomal peptide synthetases NocA and NocB in the biosynthesis of nocardicin A. Chem Biol 19: 297-306.
29. Dehghani, M., and Davarpanah, M.A. (2009) Epididymo-orchitis and central nervous system nocardiosis in a bone marrow transplant recipient for acute lymphoblastic leukemia. Exp Clin Transplant 7: 264-266.
30. Denome, S.A., Oldfield, C., Nash, L.J., and Young, K.D. (1994) Characterization of the desulfurization genes from Rhodococcus sp. strain IGTS8. J Bacteriol 176: 6707-6716.
31. El-Gendy, M.M., Hawas, U.W., and Jaspars, M. (2008) Novel bioactive metabolites from a marine derived bacterium Nocardia sp. ALAA 2000. J Antibiot (Tokyo) 61: 379-386.
32. Fu, Y., Shao, L., Tong, L., and Liu, H. (2011) Ethylene removal efficiency and bacterial community diversity of a natural zeolite biofilter. Bioresour Technol 102: 576-584.
33. Furuhashi, K., Taoka, A., Uchida, S., Karube, I., and Suzuki, S. (1981) Production of 1, 2-epoxyalkanes from 1-alkenes by Nocardia corallina B-276. Eur J Appl Microbiol Biotechnol 12: 39-45.
34. Georghiou, P.R., and Blacklock, Z.M. (1992) Infection with Nocardia species in Queensland. A review of 102 clinical isolates. Med J Aust 156: 692-697.
35. Gevers, D., Cohan, F.M., Lawrence, J.G., Spratt, B.G., Coenye, T., Feil, E.J., etal. (2005) Opinion: re-evaluating prokaryotic species. Nat Rev Microbiol 3: 733-739.
36. Goodfellow, M. (1971) Numerical taxonomy of some nocardioform bacteria. J Gen Microbiol 69: 33-80.
37. Goodfellow, M., Kämpfer, P., Busse, H.J., Trujillo, M.E., Suzuki, K., Ludwig, W., and Whitman, W.B. (2012) Bergey's Manual of Systematic Bacteriology. Second Edition. Volume Five. New York, USA: Springer.
38. Gordon, R.E., and Mihm, J.M. (1957) A comparative study of some strains received as nocardiae. J Bacteriol 73: 15-27.
39. Gordon, R.E., and Mihm, J.M. (1959) A comparison of Nocardia asteroides and Nocardia brasiliensis. J Gen Microbiol 20: 129-135.
40. Gordon, R.E., and Mihm, J.M. (1962a) Identification of Nocardia caviae (Erikson) nov. comb. Ann NY Acad Sci 98: 628-636.
41. Gordon, R.E., and Mihm, J.M. (1962b) The type species of the genus Nocardia. J Gen Microbiol 27: 1-10.
42. Gunsior, M., Breazeale, S.D., Lind, A.J., Ravel, J., Janc, J.W., and Townsend, C.A. (2004) The biosynthetic gene cluster for a monocyclic β-lactam antibiotic, nocardicin A. Chem Biol 11: 927-938.
43. Hahn, V., Sunwoldt, K., Mikolasch, A., and Schauer, F. (2013) Two different primary oxidation mechanisms during biotransformation of thymol by Gram-positive bacteria of the genera Nocardia and Mycobacterium. Appl Microbiol Biotechnol 97: 1289-1297.
44. 14C-labelled lignins. Arch Microbiol 119: 103-106.
45. Hashimoto, M., Komori, T., and Kamiya, T. (1976) Nocardicin A, a new monocyclic β-lactam antibiotic. II. Structure determination of nocardicins A and B. J Antibiot (Tokyo) 29: 890-901.
46. Hashimoto, M., Johkura, K., Ichikawa, T., and Shinonaga, M. (2008) Brain abscess caused by Nocardia nova. J Clin Neurosci 15: 87-89.
47. Hayashi, Y., Matsuura, N., Toshima, H., Itoh, N., Ishikawa, J., Mikami, Y., and Dairi, T. (2008) Cloning of the gene cluster responsible for the biosynthesis of brasilicardin A, a unique diterpenoid. J Antibiot (Tokyo) 61: 164-174.
48. Hiessl, S., Schuldes, J., Thurmer, A., Halbsguth, T., Bröker, D., Angelov, A., etal. (2012) Involvement of two latex clearing proteins during rubber degradation and insights into the subsequent degradation pathway revealed by the genome sequence of Gordonia polyisoprenivorans strain VH2. Appl Environ Microbiol 78: 2874-2887.
49. Hoshino, Y., Mukai, A., Yazawa, K., Uno, J., Ishikawa, J., Ando, A., etal. (2004a) Transvalencin A, a thiazolidine zinc complex antibiotic produced by a clinical isolate of Nocardia transvalensis. I. Taxonomy, fermentation, isolation and biological activities. J Antibiot (Tokyo) 57: 797-802.
50. Hoshino, Y., Mukai, A., Yazawa, K., Uno, J., Ando, A., Mikami, Y., etal. (2004b) Transvalencin A, a thiazolidine zinc complex antibiotic produced by a clinical isolate of Nocardia transvalensis. II. Structure elucidation. J Antibiot (Tokyo) 57: 803-807.
51. Hoshino, Y., Watanabe, K., Iida, S., Suzuki, S., Kudo, T., Kogure, T., etal. (2007) Nocardia terpenica sp. nov., isolated from Japanese patients with nocardiosis. Int J Syst Evol Microbiol 57: 1456-1460.
52. Hoshino, Y., Fujii, S., Shinonaga, H., Arai, K., Saito, F., Fukai, T., etal. (2010) Monooxygenation of rifampicin catalyzed by the rox gene product of Nocardia farcinica: structure elucidation, gene identification and role in drug resistance. J Antibiot (Tokyo) 63: 23-28.
53. Hoshino, Y., Chiba, K., Ishino, K., Fukai, T., Igarashi, Y., Yazawa, K., etal. (2011) Identification of nocobactin NA biosynthetic gene clusters in Nocardia farcinica. J Bacteriol 193: 441-448.
54. Hosoda, J., Konomi, T., Tani, N., and Aoki, H. (1977) Isolation of new nocardicins from Nocardia uniformis subs. tsuyamanensis. Agric Biol Chem 41: 2013-2020.
55. Husain, S., McCurry, K., Dauber, J., Singh, N., and Kusne, S. (2002) Nocardia infection in lung transplant recipients. J Heart Lung Transplant 21: 354-359.
56. Ibrahim, E.M., Arenskötter, M., Luftmann, H., and Steinbüchel, A. (2006) Identification of poly(cis-1, 4-isoprene) degradation intermediates during growth of moderately thermophilic actinomycetes on rubber and cloning of a functional lcp homologue from Nocardia farcinica strain E1. Appl Environ Microbiol 72: 3375-3382.
57. Igarashi, M., Nakamura, H., Naganawa, H., and Takeuchi, T. (2000a) Tubelactomicin A, a novel 16-membered lactone antibiotic, from Nocardia sp. II. Structure elucidation. J Antibiot (Tokyo) 53: 1102-1107.
58. Igarashi, M., Hayashi, C., Homma, Y., Hattori, S., Kinoshita, N., Hamada, M., and Takeuchi, T. (2000b) Tubelactomicin A, a novel 16-membered lactone antibiotic, from Nocardia sp. I. Taxonomy, production, isolation and biological properties. J Antibiot (Tokyo) 53: 1096-1101.
59. Ikeda, Y., Furumai, T., and Igarashi, Y. (2005a) Nocardimicins G, H and I, siderophores with muscarinic M3 receptor binding inhibitory activity from Nocardia nova JCM 6044. J Antibiot (Tokyo) 58: 566-572.
60. Ikeda, Y., Nonaka, H., Furumai, T., Onaka, H., and Igarashi, Y. (2005b) Nocardimicins A, B, C, D, E, and F, siderophores with muscarinic M3 receptor inhibiting activity from Nocardia sp. TP-A0674. J Nat Prod 68: 1061-1065.
61. Imai, K., Koibuchi, T., Kikuchi, T., Koga, M., Nakamura, H., Miura, T., etal. (2011) Pulmonary nocardiosis caused by Nocardia exalbida complicating Pneumocystis pneumonia in an HIV-infected patient. J Infect Chemother 17: 547-551.
62. Imai, T., Yazawa, K., Tanaka, Y., Mikami, Y., Kudo, T., Suzuki, K., etal. (1997) Productivity of antimicrobial substance in pathogenic actinomycetes Nocardia brasiliensis. Microbiol Cult Coll 13: 103-108.
63. Ishikawa, J., Yamashita, A., Mikami, Y., Hoshino, Y., Kurita, H., Hotta, K., etal. (2004) The complete genomic sequence of Nocardia farcinica IFM 10152. Proc Natl Acad Sci USA 101: 14925-14930.
64. Ishikawa, J., Chiba, K., Kurita, H., and Satoh, H. (2006) Contribution of rpoB2 RNA polymerase β subunit gene to rifampin resistance in Nocardia species. Antimicrob Agents Chemother 50: 1342-1346.
65. Isik, K., Chun, J., Hah, Y.C., and Goodfellow, M. (1999) Nocardia salmonicida nom. rev., a fish pathogen. Int J Syst Bacteriol 49: 833-837.
66. Itoh, J., and Miyadoh, S. (1992) SF2457, a new antibiotic related to amicetin. J Antibiot (Tokyo) 45: 846-853.
67. Iwahori, K., Wang, M., Taki, H., and Fujita, M. (1995) Comparative studies on utilization of fatty acids and hydrocarbons in Nocardia amarae and Rhodococcus spp. J Fermen Bioeng 79: 186-189.
68. Jannat-Khah, D., Kroppenstedt, R.M., Klenk, H.P., Spröer, C., Schumann, P., Lasker, B.A., etal. (2010) Nocardia mikamii sp. nov., isolated from human pulmonary infections in the USA. Int J Syst Evol Microbiol 60: 2272-2276.
69. Kageyama, A., Torikoe, K., Iwamoto, M., Masuyama, J., Shibuya, Y., Okazaki, H., etal. (2004) Nocardia arthritidis sp. nov., a new pathogen isolated from a patient with rheumatoid arthritis in Japan. J Clin Microbiol 42: 2366-2371.
70. Kageyama, A., Yazawa, K., Taniguchi, H., Chibana, H., Nishimura, K., Kroppenstedt, R.M., and Mikami, Y. (2005) Nocardia concava sp. nov., isolated from Japanese patients. Int J Syst Evol Microbiol 55: 2081-2083.
71. Kalscheuer, R., Arenskötter, M., and Steinbüchel, A. (1999) Establishment of a gene transfer system for Rhodococcus opacus PD630 based on electroporation and its application for recombinant biosynthesis of poly(3-hydroxyalkanoic acids). Appl Microbiol Biotechnol 52: 508-515.
72. Kämpfer, P., Buczolits, S., Jäckel, U., Grün-Wollny, I., and Busse, H.J. (2004) Nocardia tenerifensis sp. nov. Int J Syst Evol Microbiol 54: 381-383.
73. Khanna, A.K. (2000) Mechanism of the combination immunosuppressive effects of rapamycin with either cyclosporine or tacrolimus. Transplantation 70: 690-694.
74. Kim, S.H., Yoo, J.C., and Kim, T.S. (2009) Nargenicin enhances 1, 25-dihydroxyvitamin D(3)- and all-trans retinoic acid-induced leukemia cell differentiation via PKCbetaI/MAPK pathways. Biochem Pharmacol 77: 1694-1701.
75. Kinoshita, N., Homma, Y., Igarashi, M., Ikeno, S., Hori, M., and Hamada, M. (2001) Nocardia vinacea sp. nov. Actinomycetologica 15: 1-5.
76. Kobayashi, J., Tsuda, M., Nemoto, A., Tanaka, Y., Yazawa, K., and Mikami, Y. (1997) Brasilidine A, a new cytotoxic isonitrile-containing indole alkaloid from the actinomycete Nocardia brasiliensis. J Nat Prod 60: 719-720.
77. Kokubo, S., Suenaga, K., Shinohara, C., Tsuji, T., and Uemura, D. (2000) Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from Nocardia asteroides. Tetrahedron 56: 6435-6440.
78. Komaki, H., Nemoto, A., Tanaka, Y., Takagi, H., Yazawa, K., Mikami, Y., etal. (1999) Brasilicardin A, a new terpenoid antibiotic from pathogenic Nocardia brasiliensis: fermentation, isolation and biological activity. J Antibiot (Tokyo) 52: 13-19.
79. Komaki, H., Tanaka, Y., Yazawa, K., Takagi, H., Ando, A., Nagata, Y., and Mikami, Y. (2000) Antitumor activity of brasilicardin A, a novel terpenoid antibiotic from Nocardia brasiliensis. J Antibiot (Tokyo) 53: 75-77.
80. Komatsu, K., Tsuda, M., Shiro, M., Tanaka, Y., Mikami, Y., and Kobayashi, J. (2004) Brasilicardins B-D, new tricyclic terpenoids from actinomycete Nocardia brasiliensis. Bioorg Med Chem 12: 5545-5551.
81. Kumagai, K., Taya, K., Fukui, A., Fukasawa, M., Fukui, M., and Nabeshima, S. (1993a) PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. I. Taxonomy, fermentation and biological activity. J Antibiot (Tokyo) 46: 972-978.
82. Kumagai, K., Fukui, A., Tanaka, S., Ikemoto, M., Moriguchi, K., and Nabeshima, S. (1993b) PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. II. Isolation, physico-chemical properties and structure elucidation. J Antibiot (Tokyo) 46: 1139-1144.
83. Kurita, M., Jomon, K., Komori, T., Miyairi, N., Aoki, H., Kuge, S., etal. (1976) Isolation and characterization of nocardicin B. J Antibiot (Tokyo) 29: 1243-1245.
84. Kurup, P.V., and Sandhu, R.S. (1965) Isolation of Nocardia caviae from soil and its pathogenicity for laboratory animals. J Bacteriol 90: 822-823.
85. Kurup, P.V., and Schmitt, J.A. (1973) Numerical taxonomy of Nocardia. Can J Microbiol 19: 1035-1048.
86. Lalitha, P., Srinivasan, M., Rajaraman, R., Ravindran, M., Mascarenhas, J., Priya, J.L., etal. (2012) Nocardia keratitis: clinical course and effect of corticosteroids. Am J Ophthalmol 154: 934-939.
87. Le, T.N., Mikolasch, A., Awe, S., Sheikhany, H., Klenk, H.P., and Schauer, F. (2010) Oxidation of aliphatic, branched chain, and aromatic hydrocarbons by Nocardia cyriacigeorgica isolated from oil-polluted sand samples collected in the Saudi Arabian desert. J Basic Microbiol 50: 241-253.
88. Leet, J.E., Li, W., Ax, H.A., Matson, J.A., Huang, S., Huang, R., etal. (2003) Nocathiacins, new thiazolyl peptide antibiotics from Nocardia sp. II. Isolation, characterization, and structure determination. J Antibiot (Tokyo) 56: 232-242.
89. Li, W., Leet, J.E., Ax, H.A., Gustavson, D.R., Brown, D.M., Turner, L., etal. (2003) Nocathiacins, new thiazolyl peptide antibiotics from Nocardia sp. I. Taxonomy, fermentation and biological activities. J Antibiot (Tokyo) 56: 226-231.
90. Lievano, R., Pérez, H.I., Manjarrez, N., Solís, A., and Solís-Oba, M. (2012) Hydrolysis of ibuprofen nitrile and ibuprofen amide and deracemisation of ibuprofen using Nocardia corallina B-276. Molecules 17: 3148-3154.
91. Lloyd, M.D., Darley, D.J., Wierzbicki, A.S., and Threadgill, M.D. (2008) α-Methylacyl-CoA racemase - an 'obscure' metabolic enzyme takes centre stage. FEBS J 275: 1089-1102.
92. van Loosdrecht, M.C., Lyklema, J., Norde, W., Schraa, G., and Zehnder, A.J. (1987) The role of bacterial cell wall hydrophobicity in adhesion. Appl Environ Microbiol 53: 1893-1897.
93. Luo, Q., Hiessl, S., Poehlein, A., and Steinbüchel, A. (2013) Microbial gutta-percha degradation shares common steps with rubber degradation by Nocardia nova SH22a. Appl Environ Microbiol 79: 1140-1149.
94. McTaggart, L.R., Richardson, S.E., Witkowska, M., and Zhang, S.X. (2010) Phylogeny and identification of Nocardia species on the basis of multilocus sequence analysis. J Clin Microbiol 48: 4525-4533.
95. McVeigh, H.P., Munro, J., and Embley, T.M. (1994) The phylogenetic position of Pseudoamycolata halophobica (Akimov etal. 1989) and a proposal to reclassify it as Pseudonocardia halophobica. Int J Syst Bacteriol 44: 300-302.
96. Maeda, A., Yazawa, K., Mikami, Y., Ishibashi, M., and Kobayashi, J. (1992) The producer and biological activities of SO-75R1, a new mutactimycin group antibiotic. J Antibiot (Tokyo) 45: 1848-1852.
97. Maeda, A., Nagai, H., Yazawa, K., Tanaka, Y., Imai, T., Mikami, Y., etal. (1994) Three new reduced anthracycline related compounds from pathogenic Nocardia brasiliensis. J Antibiot (Tokyo) 47: 976-981.
98. 1. Appl Biochem Biotechnol 166: 805-817.
99. Maiden, M.C., Bygraves, J.A., Feil, E., Morelli, G., Russell, J.E., Urwin, R., etal. (1998) Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms. Proc Natl Acad Sci USA 95: 3140-3145.
100. Mari, B., Montón, C., Mariscal, D., Luján, M., Sala, M., and Domingo, C. (2001) Pulmonary nocardiosis: clinical experience in ten cases. Respiration 68: 382-388.
101. Martínez, R., Reyes, S., and Menéndez, R. (2008) Pulmonary nocardiosis: risk factors, clinical features, diagnosis and prognosis. Curr Opin Pulm Med 14: 219-227.
102. Martínez Tomás, R., Menéndez Villanueva, R., Reyes Calzada, S., Santos Durantez, M., Vallés Tarazona, J.M., Modesto Alapont, M., and Gobernado Serrano, M. (2007) Pulmonary nocardiosis: risk factors and outcomes. Respirology 12: 394-400.
103. Mathew, C.D., Nagasawa, T., Kobayashi, M., and Yamada, H. (1988) Nitrilase-catalyzed production of nicotinic acid from 3-cyanopyridine in Rhodococcus rhodochrous J1. Appl Environ Microbiol 54: 1030-1032.
104. Menéndez, R., Cordero, P.J., Santos, M., Gobernado, M., and Marco, V. (1997) Pulmonary infection with Nocardia species: a report of 10 cases and review. Eur Respir J 10: 1542-1546.
105. Mikami, Y. (2007) Biological work on medically important Nocardia species. Actinomycetologica 21: 46-51.
106. Mikami, Y., Yu, S.F., Yazawa, K., Fukushima, K., Maeda, A., Uno, J., etal. (1990) A toxic substance produced by Nocardia otitidiscaviarum isolated from cutaneous nocardiosis. Mycopathologia 112: 113-118.
107. Mikami, Y., Yazawa, K., Ohashi, S., Maeda, A., Akao, M., Ishibashi, M., etal. (1992) SO-75R1, a new mutactimycin derivative produced by Nocardia brasiliensis. J Antibiot (Tokyo) 45: 995-997.
108. Mikami, Y., Yazawa, K., Nemoto, A., Komaki, H., Tanaka, Y., and Gräfe, U. (1999) Production of erythromycin E by pathogenic Nocardia brasiliensis. J Antibiot (Tokyo) 52: 201-202.
109. Mikami, Y., Komaki, H., Imai, T., Yazawa, K., Nemoto, A., Tanaka, Y., and Gräefe, U. (2000) A new antifungal macrolide component, brasilinolide B, produced by Nocardia brasiliensis. J Antibiot (Tokyo) 53: 70-74.
110. Mine, Y., Nonoyama, S., Kojo, H., Fukada, S., and Nishida, M. (1977a) Nocardicin A, a new monocyclic β-lactam antibiotic. V. In vivo evaluation. J Antibiot (Tokyo) 30: 932-937.
111. Mine, Y., Nonoyama, S., Kojo, H., Fukada, S., and Nishida, M. (1977b) Nocardicin A, a new monocyclic β-lactam antibiotic. VI. Absorption, excretion and tissue distribution in animals. J Antibiot (Tokyo) 30: 938-944.
112. Minero, M.V., Marín, M., Cercenado, E., Rabadán, P.M., Bouza, E., and Muñoz, P. (2009) Nocardiosis at the turn of the century. Medicine (Baltimore) 88: 250-261.
113. Miyadoh, S., Amano, S., and Shomura, T. (1990) Strain SF2457, a new producer of amicetin group antibiotic. Actinomycetologica 4: 85-88.
114. Moe, W.M., Hu, W., Key, T.A., and Bowman, K.S. (2013) Removal of the sesquiterpene β-caryophyllene from air via biofiltration: performance assessment and microbial community structure. Biodegradation 24: 685-698.
115. Momose, I., Kinoshita, N., Sawa, R., Naganawa, H., Iinuma, H., Hamada, M., and Takeuchi, T. (1998) Nothramicin, a new anthracycline antibiotic from Nocardia sp. MJ896-43F17. J Antibiot (Tokyo) 51: 130-135.
116. Motozaki, T., Sawamura, K., Suzuki, A., Yoshida, K., Ueki, T., Ohara, A., etal. (2005a) Total synthesis of (+)-tubelactomicin A. 2. Synthesis of the upper-half segment and completion of the total synthesis. Org Lett 7: 2265-2267.
117. Motozaki, T., Sawamura, K., Suzuki, A., Yoshida, K., Ueki, T., Ohara, A., etal. (2005b) Total synthesis of (+)-tubelactomicin A. 1. Stereoselective synthesis of the lower-half segment by an intramolecular Diels-Alder approach. Org Lett 7: 2261-2264.
118. Mukai, A., Fukai, T., Matsumoto, Y., Ishikawa, J., Hoshino, Y., Yazawa, K., etal. (2006) Transvalencin Z, a new antimicrobial compound with salicylic acid residue from Nocardia transvalensis IFM 10065. J Antibiot (Tokyo) 59: 366-369.
119. Mukai, A., Fukai, T., Hoshino, Y., Yazawa, K., Harada, K., and Mikami, Y. (2009) Nocardithiocin, a novel thiopeptide antibiotic, produced by pathogenic Nocardia pseudobrasiliensis IFM 0757. J Antibiot (Tokyo) 62: 613-619.
120. Murakami, Y., Kato, S., Nakajima, M., Matsuoka, M., Kawai, H., Shin-Ya, K., and Seto, H. (1996) Formobactin, a novel free radical scavenging and neuronal cell protecting substance from Nocardia sp. J Antibiot (Tokyo) 49: 839-845.
121. Nemoto, A., Tanaka, Y., Karasaki, Y., Komaki, H., Yazawa, K., Mikami, Y., etal. (1997) Brasiliquinones A, B and C, new benz[α]anthraquinone antibiotics from Nocardia brasiliensis. I. Producing strain, isolation and biological activities of the antibiotics. J Antibiot (Tokyo) 50: 18-21.
122. Nemoto, A., Hoshino, Y., Yazawa, K., Ando, A., Mikami, Y., Komaki, H., etal. (2002) Asterobactin, a new siderophore group antibiotic from Nocardia asteroides. J Antibiot (Tokyo) 55: 593-597.
123. Nishida, M., Mine, Y., Nonoyama, S., and Kojo, H. (1977) Nocardicin A, a new monocyclic β-lactam antibiotic. III. In vitro evaluation. J Antibiot (Tokyo) 30: 917-925.
124. Nocard, E. (1888) Note sur la maladie des boeufs de la Gouadeloupe connue sous le nom de farcin. Ann Inst Pasteur 2: 293-302.
125. Norris, D.B., and Trudgill, P.W. (1971) The metabolism of cyclohexanol by Nocardia globerula CL1. Biochem J 121: 363-370.
126. Ntziora, F., and Falagas, M.E. (2007) Linezolid for the treatment of patients with central nervous system infection. Ann Pharmacother 41: 296-308.
127. Ottengraf, S.P.P., Meesters, J.J.P., Vandenoever, A.H.C., and Rozema, H.R. (1986) Biological elimination of volatile xenobiotic compounds in biofilters. Bioprocess Eng 1: 61-69.
128. Park, S.J., Lee, I.S., Chang, Y.K., and Lee, S.Y. (2003) Desulfurization of dibenzothiophene and diesel oil by metabolically engineered Escherichia coli. J Microbiol Biotechnol 13: 578-583.
129. Patel, J.B., Wallace, R.J., Jr, Brown-Elliott, B.A., Taylor, T., Imperatrice, C., Leonard, D.G., etal. (2004) Sequence-based identification of aerobic actinomycetes. J Clin Microbiol 42: 2530-2540.
130. Peraira, J.R., Segovia, J., Fuentes, R., Jiménez-Mazuecos, J., Arroyo, R., Fuertes, B., etal. (2003) Pulmonary nocardiosis in heart transplant recipients: treatment and outcome. Transplant Proc 35: 2006-2008.
131. Pérez, H.I., Manjarrez, N., Luna, H., Solís, A., and Ramírez, C. (2005) Nitrile hydratase activity of Nocardia corallina B-276. J Braz Chem Soc 16: 1150-1153.
132. Piddington, C.S., Kovacevich, B.R., and Rambosek, J. (1995) Sequence and molecular characterization of a DNA region encoding the dibenzothiophene desulfurization operon of Rhodococcus sp. strain IGTS8. Appl Environ Microbiol 61: 468-475.
133. Quatrini, P., Scaglione, G., De Pasquale, C., Riela, S., and Puglia, A.M. (2008) Isolation of Gram-positive n-alkane degraders from a hydrocarbon-contaminated mediterranean shoreline. J Appl Microbiol 104: 251-259.
134. Queipo-Zaragozá, J.A., Broseta-Rico, E., Alapont-Alacreu, J.M., Santos-Durantez, M., Sánchez-Plumed, J., and Jiménez-Cruz, J.F. (2004) Nocardial infection in immunosuppressed kidney transplant recipients. Scand J Urol Nephrol 38: 168-173.
135. Ramos-Vara, J.A., Wu, C.C., Lin, T.L., and Miller, M.A. (2007) Nocardia tenerifensis genome identification in a cutaneous granuloma of a cat. J Vet Diagn Invest 19: 577-580.
136. Ratledge, C., and Snow, G.A. (1974) Isolation and structure of nocobactin NA, a lipid-soluble iron-binding compound from Nocardia asteroides. Biochem J 139: 407-413.
137. Roberts, S.A., Franklin, J.C., Mijch, A., and Spelman, D. (2000) Nocardia infection in heart-lung transplant recipients at Alfred Hospital, Melbourne, Australia, 1989-1998. Clin Infect Dis 31: 968-972.
138. Roth, A., Andrees, S., Kroppenstedt, R.M., Harmsen, D., and Mauch, H. (2003) Phylogeny of the genus Nocardia based on reassessed 16S rRNA gene sequences reveals underspeciation and division of strains classified as Nocardia asteroides into three established species and two unnamed taxons. J Clin Microbiol 41: 851-856.
139. Ruimy, R., Boiron, P., Boivin, V., and Christen, R. (1994) A phylogeny of the genus Nocardia deduced from the analysis of small-subunit ribosomal DNA sequences, including transfer of Nocardia amarae to the genus Gordona as Gordona amarae comb. nov. FEMS Microbiol Lett 123: 261-267.
140. Rutherford, K., Parkhill, J., Crook, J., Horsnell, T., Rice, P., Rajandream, M.A., and Barrell, B. (2000) Artemis: sequence visualization and annotation. Bioinformatics 16: 944-945.
141. Saintpierre-Bonaccio, D., Maldonado, L.A., Amir, H., Pineau, R., and Goodfellow, M. (2004) Nocardia neocaledoniensis sp. nov., a novel actinomycete isolated from a New-Caledonian brown hypermagnesian ultramafic soil. Int J Syst Evol Microbiol 54: 599-603.
142. Saitou, N., and Nei, M. (1987) The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 4: 406-425.
143. Sakagami, H., Ishihara, M., Hoshino, Y., Ishikawa, J., Mikami, Y., and Fukai, T. (2005) Cytotoxicity of nocobactins NA-a, NA-b and their ferric complexes assessed by semiempirical molecular orbital method. In Vivo 19: 277-282.
144. Sánchez-Herrera, K., Sandoval, H., Couble, A., Mouniee, D., Ramírez-Durán, N., Uzcategui de Morillo, M., etal. (2012) Phenotypic and genotypic evaluation of 18 Nocardia isolates from human clinical samples in Mexico. J Mycol Med 22: 1-7.
145. Sariaslani, F.S., Harper, D.B., and Higgins, I.J. (1974) Microbial degradation of hydrocarbons. Catabolism of 1-phenylalkanes by Nocardia salmonicolor. Biochem J 140: 31-45.
146. Schneider, K., Rose, I., Vikineswary, S., Jones, A.L., Goodfellow, M., Nicholson, G., etal. (2007) Nocardichelins A and B, siderophores from Nocardia strain Acta 3026. J Nat Prod 70: 932-935.
147. Schulze, B., and Wubbolts, M.G. (1999) Biocatalysis for industrial production of fine chemicals. Curr Opin Biotechnol 10: 609-615.
148. Sharma, N.N., Sharma, M., and Bhalla, T.C. (2011) An improved nitrilase-mediated bioprocess for synthesis of nicotinic acid from 3-cyanopyridine with hyperinduced Nocardia globerula NHB-2. J Ind Microbiol Biotechnol 38: 1235-1243.
149. Sharma, N.N., Sharma, M., and Bhalla, T.C. (2012) Nocardia globerula NHB-2 nitrilase catalysed biotransformation of 4-cyanopyridine to isonicotinic acid. AMB Express 2: 25.
150. Shavandi, M., Sadeghizadeh, M., Zomorodipour, A., and Khajeh, K. (2009) Biodesulfurization of dibenzothiophene by recombinant Gordonia alkanivorans RIPI90A. Bioresour Technol 100: 475-479.
151. Shigemori, H., Tanaka, Y., Yazawa, K., Mikami, Y., and Kobayashi, J. (1996) Brasilinolide A, new immunosuppressive macrolide from actinomycete Nocardia brasiliensis. Tetrahedron 52: 9031-9034.
152. Shigemori, H., Komaki, H., Yazawa, K., Mikami, Y., Nemoto, A., Tanaka, Y., etal. (1998) Brasilicardin A. A novel tricyclic metabolite with potent immunosuppressive activity from actinomycete Nocardia brasiliensis. J Org Chem 63: 6900-6904.
153. Shneyer, V.S. (2007) On the species-specificity of DNA: fifty years later. Biochemistry (Mosc) 72: 1377-1384.
154. Skerman, V.B.D., McGowan, V., and Sneath, P.H.A. (1980) Approved lists of bacterial names. Int J Syst Bacteriol 30: 225-420.
155. Smith, A., Tranter, E.K., and Cain, R.B. (1968) The utilization of some halogenated aromatic acids by Nocardia. Effects on growth and enzyme induction. Biochem J 106: 203-209.
156. Smith, M.R. (1990) The biodegradation of aromatic hydrocarbons by bacteria. Biodegradation 1: 191-206.
157. Sohng, J.K., Yamaguchi, T., Seong, C.N., Baik, K.S., Park, S.C., Lee, H.J., etal. (2008) Production, isolation and biological activity of nargenicin from Nocardia sp. CS682. Arch Pharm Res 31: 1339-1345.
158. Suenaga, K., Kokubo, S., Shinohara, C., Tsuji, T., and Uemura, D. (1999) Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from an actinomycete. Tetrahedron Lett 40: 1945-1948.
159. Tamura, T., Matsuzawa, T., Oji, S., Ichikawa, N., Hosoyama, A., Katsumata, H., etal. (2012) A genome sequence-based approach to taxonomy of the genus Nocardia. Antonie Van Leeuwenhoek 102: 481-491.
160. Tanaka, Y., Gräfe, U., Yazawa, K., Mikami, Y., and Ritzau, M. (1997a) Nocardicyclins A and B: new anthracycline antibiotics produced by Nocardia pseudobrasiliensis. J Antibiot (Tokyo) 50: 822-827.
161. Tanaka, Y., Komaki, H., Yazawa, K., Mikami, Y., Nemoto, A., Tojyo, T., etal. (1997b) Brasilinolide A, a new macrolide antibiotic produced by Nocardia brasiliensis: producing strain, isolation and biological activity. J Antibiot (Tokyo) 50: 1036-1041.
162. Tatsuta, K., and Hosokawa, S. (2006) Total syntheses of polyketide-derived bioactive natural products. Chem Rec 6: 217-233.
163. Townsend, C.A., and Brown, A.M. (1981) Biosynthetic studies of nocardicin A. J Am Chem Soc 103: 2873-2874.
164. Townsend, C.A., and Brown, A.M. (1983) Nocardicin A: biosynthetic experiments with amino acid precursors. J Am Chem Soc 105: 913-918.
165. Trevisan, V. (1889) I Generi e le Specie Delle Batteriacee. Milano, Italy: Zanaboni and Gabuzzi.
166. Tsuchii, A., Suzuki, T., and Takeda, K. (1985) Microbial degradation of natural rubber vulcanizates. Appl Environ Microbiol 50: 965-970.
167. Tsuda, M., Sato, H., Tanaka, Y., Yazawa, G., Mikami, Y., Sasaki, T., and Kobayashi, J. (1996) Brasiliquinones A-C, new cytotoxic benz[α]anthraquinones with an ethyl group at C-3 from actinomycete Nocardia brasiliensis. J Chem Soc, Perkin Trans 1: 1773-1775.
168. Tsuda, M., Nemoto, A., Komaki, H., Tanaka, Y., Yazawa, K., Mikami, Y., and Kobayashi, J. (1999) Nocarasins A-C and brasiliquinone D, new metabolites from the actinomycete Nocardia brasiliensis. J Nat Prod 62: 1640-1642.
169. Tsuda, M., Yamakawa, M., Oka, S., Tanaka, Y., Hoshino, Y., Mikami, Y., etal. (2005) Brasilibactin A, a cytotoxic compound from actinomycete Nocardia brasiliensis. J Nat Prod 68: 462-464.
170. Tsukamoto, M., Murooka, K., Nakajima, S., Abe, S., Suzuki, H., Hirano, K., etal. (1997) BE-32030 A, B, C, D and E, new antitumor substances produced by Nocardia sp. A32030. J Antibiot (Tokyo) 50: 815-821.
171. Tsukamura, M. (1977) Extended numerical taxonomy study of Nocardia. Int J Syst Bacteriol 27: 311-323.
172. Usui, T., Nagumo, Y., Watanabe, A., Kubota, T., Komatsu, K., Kobayashi, J., and Osada, H. (2006) Brasilicardin A, a natural immunosuppressant, targets amino acid transport system L. Chem Biol 13: 1153-1160.
173. Van Ginkel, C.G., Welten, H.G.J., Hartmans, S., and Debont, J.A.M. (1987) Metabolism of trans-2-butene and butane in Nocardia TB1. J Gen Microbiol 133: 1713-1720.
174. Vera-Cabrera, L., Ortiz-Lopez, R., Elizondo-Gonzalez, R., and Ocampo-Candiani, J. (2013) Complete genome sequence analysis of Nocardia brasiliensis HUJEG-1 reveals a saprobic lifestyle and the genes needed for human pathogenesis. PLoS One 8: e65425.
175. Wallace, R.J., Jr, Steele, L.C., Sumter, G., and Smith, J.M. (1988) Antimicrobial susceptibility patterns of Nocardia asteroides. Antimicrob Agents Chemother 32: 1776-1779.
176. Wallace, R.J., Jr, Tsukamura, M., Brown, B.A., Brown, J., Steingrube, V.A., Zhang, Y.S., and Nash, D.R. (1990) Cefotaxime-resistant Nocardia asteroides strains are isolates of the controversial species Nocardia farcinica. J Clin Microbiol 28: 2726-2732.
177. Wallace, R.J., Jr, Brown, B.A., Tsukamura, M., Brown, J.M., and Onyi, G.O. (1991) Clinical and laboratory features of Nocardia nova. J Clin Microbiol 29: 2407-2411.
178. Wang, Y.J., Zheng, Y.G., Zheng, R.C., and Shen, Y.C. (2006) Stability study on the nitrile hydratase of Nocardia sp. 108: from resting cell to crude enzyme preparation. Prikl Biokhim Mikrobiol 42: 434-437.
179. Wang, Y.J., Zheng, Y.G., Xue, J.P., and Shen, Y.C. (2007) Characterization of nitrile hydratation catalysed by Nocardia sp. 108. World J Microbiol Biotechnol 23: 355-362.
180. Warneke, S., Arenskötter, M., Tenberge, K.B., and Steinbüchel, A. (2007) Bacterial degradation of poly(trans-1, 4-isoprene) (gutta percha). Microbiology 153: 347-356.
181. Watson, A., French, P., and Wilson, M. (2001) Nocardia asteroides native valve endocarditis. Clin Infect Dis 32: 660-661.
182. Webley, D.M. (1954) The morphology of Nocardia opaca Waksman & Henrici (Proactinomyces opacus Jensen) when grown on hydrocarbons, vegetable oils, fatty acids and related substances. J Gen Microbiol 11: 420-425.
183. Webley, D.M., Duff, R.B., and Farmer, V.C. (1956) Evidence for β-oxidation in the metabolism of saturated aliphatic hydrocarbons by soil species of Nocardia. Nature 178: 1467-1468.
184. Wilson, J.W. (2012) Nocardiosis: updates and clinical overview. Mayo Clin Proc 87: 403-407.
185. Xiong, X.C., Li, W.L., Li, X., Xing, J.M., and Liu, H.Z. (2005) Comparison of the desulfurization activity among several bacteria and analysis of the conservation of their desulfurization genes. Acta Microbio Sinica 45: 733-737.
186. Yamamura, H., Hayakawa, M., Nakagawa, Y., Tamura, T., Kohno, T., Komatsu, F., and Iimura, Y. (2005) Nocardia takedensis sp. nov., isolated from moat sediment and scumming activated sludge. Int J Syst Evol Microbiol 55: 433-436.
187. Yano, I., Imaeda, T., and Tsukamura, M. (1990) Characterization of Nocardia nova. Int J Syst Bacteriol 40: 170-174.
188. Yao, W., Yang, Y., and Chiao, J. (1994) Cloning vector system for Nocardia spp. Curr Microbiol 29: 223-227.
189. Yassin, A.F., Straubler, B., Schumann, P., and Schaal, K.P. (2003) Nocardia puris sp. nov. Int J Syst Evol Microbiol 53: 1595-1599.
190. Yoo, J.C., Cho, H.S., Park, E., Park, J.A., Kim, S., Kim do, K., etal. (2009) Nargenicin attenuates lipopolysaccharide-induced inflammatory responses in BV-2 cells. Neuroreport 20: 1007-1012.
191. Zaborske, J.M., Wu, X., Wek, R.C., and Pan, T. (2010) Selective control of amino acid metabolism by the GCN2 eIF2 kinase pathway in Saccharomyces cerevisiae. BMC Biochem 11: 29.
192. Zeinali, M., Vossoughi, M., and Ardestani, S.K. (2007a) Characterization of a moderate thermophilic Nocardia species able to grow on polycyclic aromatic hydrocarbons. Lett Appl Microbiol 45: 622-628.
193. Zeinali, M., Vossoughi, M., Ardestani, S.K., Babanezhad, E., and Masoumian, M. (2007b) Hydrocarbon degradation by thermophilic Nocardia otitidiscaviarum strain TSH1: physiological aspects. J Basic Microbiol 47: 534-539.
194. Zhang, W., Jayarao, B.M., and Knabel, S.J. (2004) Multi-virulence-locus sequence typing of Listeria monocytogenes. Appl Environ Microbiol 70: 913-920.
195. Zoropogui, A., Pujic, P., Normand, P., Barbe, V., Beaman, B., Beaman, L., etal. (2012) Genome sequence of the human- and animal-pathogenic strain Nocardia cyriacigeorgica GUH-2. J Bacteriol 194: 2098-2099.
196. Zoropogui, A., Pujic, P., Normand, P., Barbe, V., Belli, P., Graindorge, A., etal. (2013) The Nocardia cyriacigeorgica GUH-2 genome shows ongoing adaptation of an environmental Actinobacteria to a pathogen's lifestyle. BMC Genomics 14: 286.