Nargenicin enhances 1,25-dihydroxyvitamin D3- and all-trans retinoic acid-induced leukemia cell differentiation via PKCβI/MAPK pathways

Biochemical Pharmacology

Volumn 77, Issue 11, 2009, Pages 1694-1701

  Kim, Seung Hyun ^a   Yoo, Jin Cheol ^b   Kim, Tae Sung ^a  

^a Korea University   (South Korea)

^b Chosun University   (South Korea)

Author keywords

1,25 Dihydroxyvitamin D3; All trans retinoic acid; Cell differentiation; Mitogen activated protein kinase; Nargenicin; Protein kinase C

Indexed keywords

BACTERIAL PROTEIN; CALCITRIOL; MITOGEN ACTIVATED PROTEIN KINASE; NARGENICIN; PROTEIN KINASE C BETA; PROTEIN KINASE C BETA1; RETINOIC ACID; UNCLASSIFIED DRUG;

ACTINOBACTERIA; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN HL 60; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOFLUOROMETRY; DRUG EFFECT; DRUG POTENTIATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LEUKEMIA CELL; MITOSIS INHIBITION; MYELOID LEUKEMIA; NOCARDIA; PRIORITY JOURNAL; WESTERN BLOTTING;

CALCITRIOL; CELL DIFFERENTIATION; CELL DIVISION; CELL SURVIVAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HL-60 CELLS; HUMANS; LACTONES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PROTEIN KINASE C; TETRADECANOYLPHORBOL ACETATE; TRETINOIN;

EID: 64249148822     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.03.004     Document Type: Article

References (37)

1. Warner J.K., Wang J.C., Hope K.J., Jin L., and Dick J.E. Concepts of human leukemic development. Oncogene 23 (2004) 7164-7177
2. Sell S. Leukemia: stem cells, maturation arrest, and differentiation therapy. Stem Cell Rev 1 (2005) 197-205
3. Zhou G.B., Zhang J., Wang Z.Y., Chen S.J., and Chen Z. Treatment of acute promyelocytic leukaemia with all-trans retinoic acid and arsenic trioxide: a paradigm of synergistic molecular targeting therapy. Philos Trans R Soc Lond B: Biol Sci 362 (2007) 959-971
4. James S.Y., Williams M.A., Newland A.C., and Colston K.W. Leukemia cell differentiation: cellular and molecular interactions of retinoids and vitamin D. Gen Pharmacol 32 (1999) 143-154
5. Tallman M.S. Differentiating therapy in acute myeloid leukemia. Leukemia 10 (1996) 1262-1268
6. Patatanian E., and Thompson D.F. Retinoic acid syndrome. J Clin Pharm Ther 33 (2008) 331-338
7. Wang Z.Y., and Chen Z. Acute promyelocytic leukemia: from highly fatal to highly curable. Blood 111 (2008) 2505-2515
8. 3-induced differentiation of human promyelocytic leukemia cells into monocytes by costunolide, a germacranolide sesquiterpene lactone. Biochem Pharmacol 64 (2002) 1233-1242
9. Matkovic K., Brugnoli F., Bertagnolo V., Banfic H., and Visnjic D. The role of the nuclear Akt activation and Akt inhibitors in all-trans-retinoic acid-differentiated HL-60 cells. Leukemia 20 (2006) 941-951
10. 3 on monocytic differentiation and myeloblastin gene down-regulation in HL60 and THP-1 human leukemia cells. Cancer Res 60 (2000) 672-678
11. 3 regulation of protein kinase C levels and activity. Biochem Pharmacol 54 (1997) 909-915
12. 3. Exp Cell Res 312 (2006) 2054-2065
13. Yamada O., Ozaki K., Nakatake M., Akiyama M., Kawauchi K., and Matsuoka R. Multistep regulation of telomerase during differentiation of HL60 cells. J Leukoc Biol 83 (2008) 1240-1248
14. 3-stimulated increase in steroid sulphatase activity in myeloid leukaemic cell lines. J Cell Biochem 103 (2008) 1551-1572
15. Wang J., and Yen A. A MAPK-positive feedback mechanism for BLR1 signaling propels retinoic acid-triggered differentiation and cell cycle arrest. J Biol Chem 283 (2008) 4375-4386
16. Weist S., and Süssmuth R.D. Mutational biosynthesis-a tool for the generation of structural diversity in the biosynthesis of antibiotics. Appl Microbiol Biotechnol 68 (2005) 141-150
17. Ganesan A. The impact of natural products upon modern drug discovery. Curr Opin Chem Biol 12 (2008) 306-317
18. Paradkar A., Trefzer A., Chakraburtty R., and Stassi D. Streptomyces genetics: a genomic perspective. Crit Rev Biotechnol 23 (2003) 1-27
19. Sohng J.K., Yamaguchi T., Seong C.N., Baik K.S., Park S.C., Lee H.J., et al. Production, isolation and biological activity of nargenicin from Nocardia sp. CS682. Arch Pharm Res 31 (2008) 1339-1345
20. Faurschou M., and Borregaard N. Neutrophil granules and secretory vesicles in inflammation. Microbes Infect 5 (2003) 1317-1327
21. Warren M.K., Rose W.L., Beall L.D., and Cone J. CD34+ cell expansion and expression of lineage markers during liquid culture of human progenitor cells. Stem Cells 13 (1995) 167-174
22. Wang Q., Salman H., Danilenko M., and Studzinski G.P. Cooperation between antioxidants and 1,25-dihydroxyvitamin D3 in induction of leukemia HL60 cell differentiation through the JNK/AP-1/Egr-1 pathway. J Cell Physiol 204 (2005) 964-974
23. Levis M., Pham R., Smith B.D., and Small D. In vitro studies of a FLT3 inhibitor combined with chemotherapy: sequence of administration is important to achieve synergistic cytotoxic effects. Blood 104 (2004) 1145-1150
24. Wang Q., Harrison J.S., Uskokovic M., Kutner A., and Studzinski G.P. Translational study of vitamin D differentiation therapy of myeloid leukemia: effects of the combination with a p38 MAPK inhibitor and an antioxidant. Leukemia 19 (2005) 1812-1817
25. Kim S.H., Danilenko M., and Kim T.S. Differential enhancement of leukaemia cell differentiation without elevation of intracellular calcium by plant-derived sesquiterpene lactone compounds. Br J Pharmacol 155 (2008) 814-825
26. 3 involves Raf1 but not Erk 1/2 signaling. Cell Cycle 7 (2008) 917-924
27. Savickiene J., Treigyte G., Borutinskaite V., Navakauskiene R., and Magnusson K.E. The histone deacetylase inhibitor FK228 distinctly sensitizes the human leukemia cells to retinoic acid-induced differentiation. Ann N Y Acad Sci 1091 (2006) 368-384
28. Ishida S., Shigemoto-Mogami Y., Shinozaki Y., Kagechika H., Shudo K., Ozawa S., et al. Differential modulation of PI3-kinase/Akt pathway during all-trans retinoic acid- and Am80-induced HL-60 cell differentiation revealed by DNA microarray analysis. Biochem Pharmacol 68 (2004) 2177-2186
29. Si J., Mueller L., Schuler A., Simon J., and Collins S.J. The retinoic acid receptor/CaMKII interaction: pharmacologic inhibition of CaMKII enhances the differentiation of myeloid leukemia cells. Blood Cells Mol Dis 39 (2007) 307-315
30. 3. Steroids 67 (2002) 457-466
31. Miranda M.B., McGuire T.F., and Johnson D.E. Importance of MEK-1/-2 signaling in monocytic and granulocytic differentiation of myeloid cell lines. Leukemia 16 (2002) 683-692
32. Schultz H., Engel K., and Gaestel M. PMA-induced activation of the p42/44ERK- and p38RK-MAP kinase cascades in HL-60 cells is PKC dependent but not essential for differentiation to the macrophage-like phenotype. J Cell Physiol 173 (1997) 310-318
33. Shen M., and Yen A. c-Cbl interacts with CD38 and promotes retinoic acid-induced differentiation and G0 arrest of human myeloblastic leukemia cells. Cancer Res 68 (2008) 8761-8769
34. 3: therapeutic implications in hemodialysis and renal transplantation. Clin Nephrol 66 (2006) 275-283
35. Wolters M. Diet and psoriasis: experimental data and clinical evidence. Br J Dermatol 153 (2005) 706-714
36. Degos L., and Wang Z.Y. All trans retinoic acid in acute promyelocytic leukemia. Oncogene 20 (2001) 7140-7145
37. van de Kerkhof P.C. Update on retinoid therapy of psoriasis in: an update on the use of retinoids in dermatology. Dermatol Ther 19 (2006) 252-263