Classical transient receptor potential 1 and 6 contribute to hypoxic pulmonary hypertension through differential regulation of pulmonary vascular functions

Hypertension

Volumn 63, Issue 1, 2014, Pages 173-180

  Xia, Yang ^a,b   Yang, Xiao Ru ^a   Fu, Zhenzhen ^a   Paudel, Omkar ^a   Abramowitz, Joel ^c   Birnbaumer, Lutz ^c   Sham, James S K ^a  

^a JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Hypertension, pulmonary; Hypoxia; TRPC1 channel; TRPC6 channel; Vascular smooth muscle

Indexed keywords

MESSENGER RNA; OXYGEN; SEROTONIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOVASCULAR FUNCTION; CHRONIC DISEASE; CONTROLLED STUDY; GENE DELETION; HEART RIGHT VENTRICLE HYPERTROPHY; HYPOXIA; LUNG ARTERY PRESSURE; LUNG BLOOD VESSEL; LUNG FUNCTION; LUNG VASCULAR RESISTANCE; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY; PULMONARY HYPERTENSION; REGULATORY MECHANISM; VASOCONSTRICTION; WILD TYPE;

HYPERTENSION, PULMONARY; HYPOXIA; TRPC1 CHANNEL; TRPC6 CHANNEL; VASCULAR SMOOTH MUSCLE;

ANIMALS; ANOXIA; DISEASE MODELS, ANIMAL; HYPERTENSION, PULMONARY; MICE; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; PULMONARY ARTERY; TRPC CATION CHANNELS; VASOMOTOR SYSTEM;

EID: 84891633620     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.113.01902     Document Type: Article

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