Humanized FcRn mouse models for evaluating pharmacokinetics of human IgG antibodies

Methods

Volumn 65, Issue 1, 2014, Pages 148-153

  Proetzel, Gabriele ^a   Roopenian, Derry C ^a  

^a JACKSON LABORATORY   (United States)

Author keywords

Efficacy; Humanized mice; Monoclonal antibody; Neonatal Fc receptor; Pharmacokinetics; Serum half life

Indexed keywords

BEVACIZUMAB; CETUXIMAB; FC RECEPTOR; IMMUNOGLOBULIN G; NEONATAL FC RECEPTOR; PROTEIN VARIANT; TRASTUZUMAB; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; BACKCROSSING; CONTROLLED STUDY; DRUG CLEARANCE; DRUG HALF LIFE; DRUG RECEPTOR BINDING; FEMALE; GENE EXPRESSION; GENETIC ENGINEERING; HUMAN; IN VIVO STUDY; MACACA FASCICULARIS; MOLECULAR CLONING; MOUSE; MOUSE MODEL; MOUSE STRAIN; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SPECIES DIFFERENCE; TRANSGENE; TRANSGENIC MOUSE; WILD TYPE;

ANIMALIA; MUS; RODENTIA;

B2M; BETA-2-MICROGLOBULIN; EFFICACY; EGFR; EMBRYONIC STEM; EPIDERMAL GROWTH FACTOR RECEPTOR; ES; FAB; FC; FC RECEPTOR IGG ALPHA CHAIN TRANSPORTER; FCGRT; FCRN; FRAGMENT CRYSTALLIZABLE; FRAGMENT OF ANTIGEN BINDING; HSA; HUMAN SERUM ALBUMIN; HUMANIZED MICE; IG; IMMUNOGLOBULIN; INTRAPERITONEAL; INTRAVENOUS; IP; IV; MAB; MADIN-DARBY CANINE KIDNEY; MAJOR HISTOCOMPATIBILITY COMPLEX; MDCK; MHC; MONOCLONAL ANTIBODY; MOUSE SERUM ALBUMIN; MSA; NEONATAL FC RECEPTOR; P; PHARMACOKINETICS; PK; PROBABILITY VALUE; SERUM HALF-LIFE; VASCULAR ENDOTHELIAL GROWTH FACTOR; VEGF;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, MONOCLONAL, HUMANIZED; HALF-LIFE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNOGLOBULIN G; MACACA FASCICULARIS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, FC;

EID: 84891627700     PISSN: 10462023     EISSN: 10959130     Source Type: Journal    
DOI: 10.1016/j.ymeth.2013.07.005     Document Type: Review

References (43)

1. Kohler G., Milstein C. Nature 1975, 256:495-497.
2. Spiegelberg H.L., Weigle W.O. J. Exp. Med. 1965, 121:323-338.
3. Murphy K., Travers P., Walport M. Janeway's Immunobiology 2008, Garland Science, New York, p. seventh ed.
4. Simister N.E., Mostov K.E. Cold Spring Harb. Symp. Quant. Biol. 1989, 54(Pt. 1):571-580.
5. Stern C.M. Immunology 1976, 30:443-448.
6. Brambell F.W., Hemmings W.A., Morris I.G. Nature 1964, 203:1352-1354.
7. Jones E.A., Waldmann T.A. J. Clin. Invest. 1972, 51:2916-2927.
8. Ghetie V., Ward E.S. Annu. Rev. Immunol. 2000, 18:739-766.
9. Roopenian D.C., Akilesh S. Nat. Rev. Immunol. 2007, 7:715-725.
10. Chaudhury C., Mehnaz S., Robinson J.M., Hayton W.L., Pearl D.K., et al. J. Exp. Med. 2003, 197:315-322.
11. Junghans R.P., Anderson C.L. Proc. Natl. Acad. Sci. USA 1996, 93:5512-5516.
12. Story C.M., Mikulska J.E., Simister N.E. J. Exp. Med. 1994, 180:2377-2381.
13. Ghetie V., Ward E.S. Immunol. Today 1997, 18:592-598.
14. Roopenian D.C., Sun V.Z. J. Clin. Immunol. 2010, 30:790-797.
15. Kuo T.T., Aveson V.G. mABs 2011, 3:422-430.
16. Kuo T.T., Baker K., Yoshida M., Qiao S.W., Aveson V.G., et al. J. Clin. Immunol. 2010, 30:777-789.
17. Martin W.L., West A.P., Gan L., Bjorkman P.J. Mol. Cell 2001, 7:867-877.
18. Wang W., Lu P., Fang Y., Hamuro L., Pittman T., et al. Drug Metab. Dispos. 2011, 39:1469-1477.
19. Ober R.J., Radu C.G., Ghetie V., Ward E.S. Int. Immunol. 2001, 13:1551-1559.
20. Andersen J.T., Daba M.B., Berntzen G., Michaelsen T.E., Sandlie I. J. Biol. Chem. 2010, 285:4826-4836.
21. Roopenian D.C., Christianson G.J., Sproule T.J., Brown A.C., Akilesh S., et al. J. Immunol. 2003, 170:3528-3533.
22. Roopenian D.C., Christianson G.J., Sproule T.J. Methods Mol. Biol. 2010, 602:93-104.
23. Petkova S.B., Akilesh S., Sproule T.J., Christianson G.J., Al Khabbaz H. Int. Immunol. 2006, 18:1759-1769.
24. Wang W., Vlasak J., Li Y., Pristatsky P., Fang Y., et al. Mol. Immunol. 2011, 48:860-866.
25. Krimpenfort P., Rudenko G., Hochstenbach F., Guessow D., Berns A., et al. EMBO J. 1987, 6:1673-1676.
26. Tam S.H., McCarthy S.G., Brosnan K., Goldberg K.M., Scallon B.J. mABs 2013, 5:1-9.
27. Zalevsky J., Chamberlain A.K., Horton H.M., Karki S., Leung I.W., et al. Nat. Biotechnol. 2010, 28:157-159.
28. Stein C., Kling L., Proetzel G., Roopenian D.C., de Angelis M.H., et al. Mamm. Genome 2012, 23:259-269.
29. Gehlsen K., Gong R., Bramhill D., Wiersma D., Kirkpatrick S., et al. mABs 2012, 4:466-474.
30. Andersen J.T., Foss S., Kenanova V.E., Olafsen T., Leikfoss I.S., et al. J. Biol. Chem. 2012, 287:22927-22937.
31. Dumont J.A., Liu T., Low S.C., Zhang X., Kamphaus G., et al. Blood 2012, 119:3024-3030.
32. Waldner M.J., Neurath M.F. Chemically induced mouse models of colitis. Curr. Protoc. Pharmacol. 2009, Chapter 5, Unit 5 55.
33. Wirtz S., Neufert C., Weigmann B., Neurath M.F. Nat. Protoc. 2007, 2:541-546.
34. Paveglio S., Puddington L., Rafti E., Matson A.P. Clin. Exp. Allergy 2012, 42:1791-1800.
35. Blyth D.I., Pedrick M.S., Savage T.J., Hessel E.M., Fattah D. Am. J. Respir. Cell Mol. Biol. 1996, 14:425-438.
36. Fox J.G., Ge Z., Whary M.T., Erdman S.E., Horwitz B.H. Mucosal Immunol. 2011, 4:22-30.
37. Medina E. Methods Mol. Biol. 2010, 602:395-403.
38. Medina E. Methods Mol. Biol. 2010, 602:411-415.
39. Medina E. Methods Mol. Biol. 2010, 602:405-410.
40. Kalish B.T., Le H.D., Gura K.M., Bistrian B.R., Puder M. PLoS One 2013, 8:e59653.
41. Fazio S., Linton M.F. Front. Biosci. 2001, 6:D515-D525.
42. Claypool S.M., Dickinson B.L., Yoshida M., Lencer W.I., Blumberg R.S. J. Biol. Chem. 2002, 277:28038-28050.
43. Datta-Mannan A., Chow C.K., Dickinson C., Driver D., Lu J., et al. Drug Metab. Dispos. 2012, 40:1545-1555.