Human FcRn transgenic mice for pharmacokinetic evaluation of therapeutic antibodies

Methods in Molecular Biology

Volumn 602, Issue , 2010, Pages 93-104

  Roopenian, Derry C ^a   Christianson, Gregory J ^a   Sproule, Thomas J ^a  

^a JACKSON LABORATORY   (United States)

Author keywords

Fc fusion proteins; FcRn; Monoclonal antibodies; pharmacokinetics; serum half life; transgenic mice

Indexed keywords

ANIMALIA; MUS MUSCULUS; RODENTIA;

ALBUMINOID; FC RECEPTOR; FC RECEPTOR, NEONATAL; HLA ANTIGEN CLASS 1; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; TRASTUZUMAB;

ANIMAL; ANIMAL MODEL; ARTICLE; C57BL MOUSE; CHEMISTRY; GENETICS; GENOTYPE; HUMAN; IMMUNOLOGY; METABOLISM; MOUSE; TRANSGENE; TRANSGENIC MOUSE;

ALBUMINS; ANIMALS; ANTIBODIES, MONOCLONAL; GENOTYPE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNOGLOBULIN G; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, ANIMAL; RECEPTORS, FC; TRANSGENES;

EID: 77449130936     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-60761-058-8_6     Document Type: Article

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