Synthesis, characterization and antimicrobial activity of some novel isoindole-1,3-dione derivatives

Der Pharma Chemica

Volumn 5, Issue 5, 2013, Pages 97-108

  Amin, Kamelia M ^a   El Masry, Afaf H ^b   Mohamed, Neama A ^b   Awad, Ghada E A ^b   Habib, Basma S ^b  

^a CAIRO UNIVERSITY   (Egypt)

^b NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Antibacterial agents; Antifungal agents; Heterocyclic derivatives; Phthalimide

Indexed keywords

2 [(4 ACETYLPHENYL AMINO)METHYL]ISOINDOLINE 1,3 DIONE DERIVATIVE; 2 [1 [4 [[(1,3 DIOXO 1,3 DIHYDRO 2H ISOINDOL 2 YL)METHYL]AMINO]PHENYL]ETHYLIDENE]HYDRAZINECARBOTHIOAMIDE; 2 [1 [4 [[(1,3 DIOXO 1,3 DIHYDRO 2H ISOINDOL 2 YL)METHYL]AMINO]PHENYL]ETHYLIDENE]HYDRAZINECARBOXAMIDE; 2 [[(4 ACETYLPHENYL)AMINO]METHYL] 1H ISOINDOLE 1,3(2H) DIONE; 2 [[4 (2 MORPHOLINO 2 THIOXOETHYL)PHENYLAMINO]METHYL]ISOINDOLINE 1,3 DIONE; 2 [[4 [2 (4 METHYLPIPERAZIN 1 YL) 2 THIOXOETHYL]PHENYLAMINO]METHYL]ISOINDOLINE 1,3 DIONE; 2 [[4 [6 (3,4 DIMETHOXYPHENYL) 2 OXO 1,2 DIHYDROPYRIMIDIN 4 YL] PHENYLAMINO]METHYL]ISOINDOLINE 1,3 DIONE; 2 [[4 [6 (3,4 DIMETHOXYPHENYL) 2 THIO 1,2 DIHYDROPYRIMIDIN 4 YL] PHENYLAMINO]METHYL]ISOINDOLINE 1,3 DIONE; 2 [[4 [6 (4 HYDROXY 3 METHOXYPHENYL) 2 OXO 1,2 DIHYDROPYRIMIDIN 4 YL] PHENYLAMINO]METHYL]ISOINDOLINE 1,3 DIONE; 2 [[4 [6 (4 HYDROXY 3 METHOXYPHENYL) 2 THIO 1,2 DIHYDROPYRIMIDIN 4 YL] PHENYLAMINO]METHYL]ISOINDOLINE 1,3 DIONE; 2 [[[4 [3 (3,4 DIMETHOXYPHENYL)PROP 2 ENOYL]PHENYL]AMINO]METHYL] 1H ISOINDOLE 1,3(2H) DIONE; 2 [[[4 [3 (3,4,5 TRIMETHOXYPHENYL)PROP 2 ENOYL]PHENYL]AMINO]METHYL] 1H ISOINDOLE 1,3(2H) DIONE; 2 [[[4 [3 (4 CHLOROPHENYL)PROP 2 ENOYL]PHENYL]AMINO]METHYL] 1H ISOINDOLE 1,3(2H) DIONE; 2 [[[4 [3 (4 HYDROXY 3 METHOXYPHENYL)PROP 2 ENOYL]PHENYL]AMINO]METHYL] 1H ISOINDOLE 1,3(2H) DIONE; 2 [[[4 [3 [4 (DIMETHYLAMINO)PHENYL]PROP 2 ENOYL]PHENYL]AMINO]METHYL] 1H ISOINDOLE 1,3(2H) DIONE; 2 [[[4 [5 (3,4,5 TRIMETHOXYPHENYL) 1 ACETYL 4,5 DIHYDRO 1H PYRAZOL 3 YL] PHENYL]AMINO]METHYL] 1H ISOINDOLE 1,3(2H) DIONE; 2 [[[4 [5 (4 CHLOROPHENYL) 1 ACETYL 4,5 DIHYDRO 1H PYRAZOL 3 YL]PHENYL]AMINO]METHYL] 1H ISOINDOLE 1,3(2H) DIONE; 2 [[[4 [5 (4 CHLOROPHENYL) 4,5 DIHYDRO 1,2 OXAZOL 3 YL]PHENYL]AMINO]METHYL] 1H ISOINDOLE 1,3(2H) DIONE; 2 [[[4 [5 (4 HYDROXY 3 METHOXYPHENYL) 4,5 DIHYDRO 1,2 OXAZOL 3 YL]PHENYL]AMINO]METHYL] 1H ISOINDOLE 1,3(2H) DIONE; 2 [[[4 [5 [4 (DIMETHYLAMINO)PHENYL] 1 PHENYL 4,5 DIHYDRO 1H PYRAZOL 3 YL]PHENYL]AMINO]METHYL] 1H ISOINDOLE 1,3(2H) DIONE; 2 [[[4 [5 [4 (DIMETHYLAMINO)PHENYL] 4,5 DIHYDRO 1H PYRAZOL 3 YL]PHENYL]AMINO]METHYL] 1H ISOINDOLE 1,3(2H) DIONE; 2 AMINO 6 [4 [[(1,3 DIOXO 1,3 DIHYDRO 2H ISOINDOL 2 YL)METHYL]AMINO]PHENYL] 4 (3,4 DIMETHOXYPHENYL) 4H PYRAN 3 CARBONITRILE; 2 AMINO 6 [4 [[(1,3 DIOXO 1,3 DIHYDRO 2H ISOINDOL 2 YL)METHYL]AMINO]PHENYL] 4 [4 (DIMETHYLAMINO)PHENYL] 4H PYRAN 3 CARBONITRILE; 4 (4 CHLOROPHENYL) 6 [4 [[(1,3 DIOXO 1,3 DIHYDRO 2H ISOINDOL 2 YL)METHYL]AMINO]PHENYL] 2 OXO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE; 6 [4 [[(1,3 DIOXO 1,3 DIHYDRO 2H ISOINDOL 2 YL)METHYL]AMINO]PHENYL] 4 (3,4 DIMETHOXYPHENYL) 2 IMINO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE; 6 [4 [[(1,3 DIOXO 1,3 DIHYDRO 2H ISOINDOL 2 YL)METHYL]AMINO]PHENYL] 4 [4 (DIMETHYLAMINO)PHENYL] 2 IMINO 1,2 DIHYDROPYRIDINE 3 CARBONITRILE; CIPROFLOXACIN; ISOINDOLE DERIVATIVE; KETOCONAZOLE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

AGAR DIFFUSION; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; COLONY FORMING UNIT; CONTROLLED STUDY; CRYSTALLIZATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; FUNGAL STRAIN; FUNGUS ISOLATION; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; MASS SPECTROMETRY; MELTING POINT; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 84891533731     PISSN: None     EISSN: 0975413X     Source Type: Journal    
DOI: None     Document Type: Article

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