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Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 10, 2011, Pages 3041-3045

Non-competitive and selective dipeptidyl peptidase IV inhibitors with phenethylphenylphthalimide skeleton derived from thalidomide-related α-glucosidase inhibitors and liver X receptor antagonists

(4) Motoshima, Kazunori a Sugita, Kazuyuki a Hashimoto, Yuichi a Ishikawa, Minoru a

a UNIVERSITY OF TOKYO (Japan)

Author keywords

Dipeptidyl peptidase IV; Enzyme inhibitor; Non competitive inhibition; Phthalimide; Subtype selectivity

Indexed keywords

ALPHA GLUCOSIDASE INHIBITOR; DIPEPTIDYL PEPTIDASE IV; DIPEPTIDYL PEPTIDASE IV INHIBITOR; DIPROTIN A; HORMONE RECEPTOR BLOCKING AGENT; LIVER X RECEPTOR ANTAGONIST; PHENETHYLPHENYLPHTHALIMIDE; THALIDOMIDE; UNCLASSIFIED DRUG;

ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; STRUCTURE ACTIVITY RELATION;

ALPHA-GLUCOSIDASES; BINDING, COMPETITIVE; DIPEPTIDYL-PEPTIDASE IV INHIBITORS; ENZYME ACTIVATION; INHIBITORY CONCENTRATION 50; KINETICS; MOLECULAR STRUCTURE; ORPHAN NUCLEAR RECEPTORS; PHTHALIMIDES; THALIDOMIDE;

EID: 79955551684 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2011.03.026 Document Type: Article

Times cited : (19)

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