Development of tryptase inhibitors derived from thalidomide

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 14, 2010, Pages 5323-5338

  Tetsuhashi, Masashi ^a   Ishikawa, Minoru ^a   Hashimoto, Mariko ^a   Hashimoto, Yuichi ^a   Aoyama, Hiroshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Inhibitor; Phthalimide; Serine protease; Thalidomide; Tryptase

Indexed keywords

2 (4 CYANOPHENYL)ISOINDOLE 1,3 DION 5 YL 3 (2 AMINOPYRIDIN 5 YL)PROPANOATE; PHTHALIMIDE DERIVATIVE; SERINE PROTEINASE; THALIDOMIDE; TRYPTASE; TRYPTASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; STRUCTURE ACTIVITY RELATION;

ENZYME INHIBITORS; HUMANS; MODELS, MOLECULAR; PHTHALIMIDES; THALIDOMIDE; TRYPTASES;

EID: 77955312720     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.05.037     Document Type: Article

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