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Volumn 8, Issue 5, 2013, Pages 1224-1238

Combinatorial assessments of brain tissue metabolomics and histopathology in rodent models of human immunodeficiency virus infection

Author keywords

Antigen preservation; Focused beam microwave irradiation; Human immunodeficiency virus type one; Magnetic resonance spectroscopy; Metabolomics; Neural antigens; neuroAIDS

Indexed keywords

ANTIRETROVIRUS AGENT; CD34 ANTIGEN; CHOLINE; CREATINE; INOSITOL; NANOMATERIAL; PHOSPHORYLCHOLINE;

EID: 84891373770     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-013-9461-9     Document Type: Article
Times cited : (26)

References (54)
  • 2
    • 80355145310 scopus 로고    scopus 로고
    • Methods development for blood borne macrophage carriage of nanoformulated antiretroviral drugs
    • doi: 10.3791/2460
    • Balkundi S, Nowacek AS, Roy U, Martinez-Skinner A, McMillan J, Gendelman HE (2010) Methods development for blood borne macrophage carriage of nanoformulated antiretroviral drugs. J Visual Exp (46). doi: 10.3791/2460
    • (2010) J Visual Exp , Issue.46
    • Balkundi, S.1    Nowacek, A.S.2    Roy, U.3    Martinez-Skinner, A.4    McMillan, J.5    Gendelman, H.E.6
  • 4
    • 84862790001 scopus 로고    scopus 로고
    • Rapid and reliable quantitation of amino acids and myo-inositol in mouse brain by high performance liquid chromatography and tandem mass spectrometry
    • 10.1016/j.jchromb.2012.01.035 22425384 10.1016/j.jchromb.2012.01.035 3322302
    • Bathena SP, Huang J, Epstein AA, Gendelman HE, Boska MD, Alnouti Y (2012) Rapid and reliable quantitation of amino acids and myo-inositol in mouse brain by high performance liquid chromatography and tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 893-894:15-20. doi: 10.1016/j.jchromb.2012.01.035
    • (2012) J Chromatogr B Analyt Technol Biomed Life Sci , vol.893-894 , pp. 15-20
    • Bathena, S.P.1    Huang, J.2    Epstein, A.A.3    Gendelman, H.E.4    Boska, M.D.5    Alnouti, Y.6
  • 6
    • 2342481248 scopus 로고    scopus 로고
    • Advances in neuroimaging for HIV-1 associated neurological dysfunction: Clues to the diagnosis, pathogenesis and therapeutic monitoring
    • 15053341 10.2174/1570162043485095 1:CAS:528:DC%2BD2cXhvVCiurs%3D
    • Boska MD, Mosley RL, Nawab M, Nelson JA, Zelivyanskaya M, Poluektova L, Uberti M, Dou H, Lewis TB, Gendelman HE (2004) Advances in neuroimaging for HIV-1 associated neurological dysfunction: Clues to the diagnosis, pathogenesis and therapeutic monitoring. Curr HIV Res 2(1):61-78
    • (2004) Curr HIV Res , vol.2 , Issue.1 , pp. 61-78
    • Boska, M.D.1    Mosley, R.L.2    Nawab, M.3    Nelson, J.A.4    Zelivyanskaya, M.5    Poluektova, L.6    Uberti, M.7    Dou, H.8    Lewis, T.B.9    Gendelman, H.E.10
  • 7
    • 84867572303 scopus 로고    scopus 로고
    • Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
    • 10.1007/s00018-012-1071-9 22821000 10.1007/s00018-012-1071-9 1:CAS:528:DC%2BC38XhtlKltLfE 3445802
    • Cho KI, Searle K, Webb M, Yi H, Ferreira PA (2012) Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Cell Mol Life Sci 69(20):3511-3527. doi: 10.1007/s00018-012-1071-9
    • (2012) Cell Mol Life Sci , vol.69 , Issue.20 , pp. 3511-3527
    • Cho, K.I.1    Searle, K.2    Webb, M.3    Yi, H.4    Ferreira, P.A.5
  • 8
    • 34249704131 scopus 로고    scopus 로고
    • Application of MRS to mouse models of neurodegenerative illness
    • 10.1002/nbm.1145 17451183 10.1002/nbm.1145
    • Choi JK, Dedeoglu A, Jenkins BG (2007) Application of MRS to mouse models of neurodegenerative illness. NMR Biomed 20(3):216-237. doi: 10.1002/nbm.1145
    • (2007) NMR Biomed , vol.20 , Issue.3 , pp. 216-237
    • Choi, J.K.1    Dedeoglu, A.2    Jenkins, B.G.3
  • 9
    • 68249156652 scopus 로고    scopus 로고
    • Dynamics of cognitive change in impaired HIV-positive patients initiating antiretroviral therapy
    • 10.1212/WNL.0b013e3181ab2b3b 19474412 10.1212/WNL.0b013e3181ab2b3b 1:STN:280:DC%2BD1MrjtVOnug%3D%3D 2725933
    • Cysique LA, Vaida F, Letendre S, Gibson S, Cherner M, Woods SP, McCutchan JA, Heaton RK, Ellis RJ (2009) Dynamics of cognitive change in impaired HIV-positive patients initiating antiretroviral therapy. Neurology 73(5):342-348. doi: 10.1212/WNL.0b013e3181ab2b3b
    • (2009) Neurology , vol.73 , Issue.5 , pp. 342-348
    • Cysique, L.A.1    Vaida, F.2    Letendre, S.3    Gibson, S.4    Cherner, M.5    Woods, S.P.6    McCutchan, J.A.7    Heaton, R.K.8    Ellis, R.J.9
  • 10
    • 81455161610 scopus 로고    scopus 로고
    • Central nervous system antiretroviral efficacy in HIV infection: A qualitative and quantitative review and implications for future research
    • 10.1186/1471-2377-11-148 22107790 10.1186/1471-2377-11-148 3252248
    • Cysique LA, Waters EK, Brew BJ (2011) Central nervous system antiretroviral efficacy in HIV infection: A qualitative and quantitative review and implications for future research. BMC Neurol 11:148. doi: 10.1186/1471-2377-11-148
    • (2011) BMC Neurol , vol.11 , pp. 148
    • Cysique, L.A.1    Waters, E.K.2    Brew, B.J.3
  • 11
    • 84869498397 scopus 로고    scopus 로고
    • Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice
    • 10.1097/QAD.0b013e328357f5ad 22824628 10.1097/QAD.0b013e328357f5ad 1:CAS:528:DC%2BC38Xhs1Wis7%2FK
    • Dash PK, Gendelman HE, Roy U, Balkundi S, Alnouti Y, Mosley RL, Gelbard HA, McMillan J, Gorantla S, Poluektova LY (2012) Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice. AIDS 26(17):2135-2144. doi: 10.1097/QAD.0b013e328357f5ad
    • (2012) AIDS , vol.26 , Issue.17 , pp. 2135-2144
    • Dash, P.K.1    Gendelman, H.E.2    Roy, U.3    Balkundi, S.4    Alnouti, Y.5    Mosley, R.L.6    Gelbard, H.A.7    McMillan, J.8    Gorantla, S.9    Poluektova, L.Y.10
  • 13
    • 62649149295 scopus 로고    scopus 로고
    • In situ 3D magnetic resonance metabolic imaging of microwave-irradiated rodent brain: A new tool for metabolomics research
    • 10.1111/j.1471-4159.2009.05967.x 19200336 10.1111/j.1471-4159.2009.05967. x 2843429
    • de Graaf RA, Chowdhury GM, Brown PB, Rothman DL, Behar KL (2009) In situ 3D magnetic resonance metabolic imaging of microwave-irradiated rodent brain: A new tool for metabolomics research. J Neurochem 109(2):494-501. doi: 10.1111/j.1471-4159.2009.05967.x
    • (2009) J Neurochem , vol.109 , Issue.2 , pp. 494-501
    • De Graaf, R.A.1    Chowdhury, G.M.2    Brown, P.B.3    Rothman, D.L.4    Behar, K.L.5
  • 14
    • 0029885802 scopus 로고    scopus 로고
    • Brain regional levels of adenosine and adenosine nucleotides in rats killed by high-energy focused microwave irradiation
    • 8699875 10.1016/0165-0270(95)00119-0 1:CAS:528:DyaK28XisV2ls7Y%3D
    • Delaney SM, Geiger JD (1996) Brain regional levels of adenosine and adenosine nucleotides in rats killed by high-energy focused microwave irradiation. J Neurosci Methods 64(2):151-156
    • (1996) J Neurosci Methods , vol.64 , Issue.2 , pp. 151-156
    • Delaney, S.M.1    Geiger, J.D.2
  • 15
    • 80052328810 scopus 로고    scopus 로고
    • Ultrafast in vivo microwave irradiation for enhanced metabolic stability of brain biopsy samples during HRMAS NMR analysis
    • 10.1016/j.jneumeth.2011.07.014 21803072 10.1016/j.jneumeth.2011.07.014 1:CAS:528:DC%2BC3MXhtFahtr7F
    • Detour J, Elbayed K, Piotto M, Moussallieh FM, Nehlig A, Namer IJ (2011) Ultrafast in vivo microwave irradiation for enhanced metabolic stability of brain biopsy samples during HRMAS NMR analysis. J Neurosci Methods 201(1):89-97. doi: 10.1016/j.jneumeth.2011.07.014
    • (2011) J Neurosci Methods , vol.201 , Issue.1 , pp. 89-97
    • Detour, J.1    Elbayed, K.2    Piotto, M.3    Moussallieh, F.M.4    Nehlig, A.5    Namer, I.J.6
  • 17
    • 84865051101 scopus 로고    scopus 로고
    • Metabolite profiles correlate closely with neurobehavioral function in experimental spinal cord injury in rats
    • 10.1371/journal.pone.0043152 22912814 10.1371/journal.pone.0043152 1:CAS:528:DC%2BC38Xht1anu7fO 3418274
    • Fujieda Y, Ueno S, Ogino R, Kuroda M, Jonsson TJ, Guo L, Bamba T, Fukusaki E (2012) Metabolite profiles correlate closely with neurobehavioral function in experimental spinal cord injury in rats. PLoS One 7(8):e43152. doi: 10.1371/journal.pone.0043152
    • (2012) PLoS One , vol.7 , Issue.8 , pp. 43152
    • Fujieda, Y.1    Ueno, S.2    Ogino, R.3    Kuroda, M.4    Jonsson, T.J.5    Guo, L.6    Bamba, T.7    Fukusaki, E.8
  • 18
    • 0023898273 scopus 로고
    • Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes
    • 3258626 10.1084/jem.167.4.1428 1:CAS:528:DyaL1cXit1Sitr0%3D
    • Gendelman HE, Orenstein JM, Martin MA, Ferrua C, Mitra R, Phipps T, Wahl LA, Lane HC, Fauci AS, Burke DS et al (1988) Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes. J Exp Med 167(4):1428-1441
    • (1988) J Exp Med , vol.167 , Issue.4 , pp. 1428-1441
    • Gendelman, H.E.1    Orenstein, J.M.2    Martin, M.A.3    Ferrua, C.4    Mitra, R.5    Phipps, T.6    Wahl, L.A.7    Lane, H.C.8    Fauci, A.S.9    Burke, D.S.10
  • 20
    • 78650966753 scopus 로고    scopus 로고
    • Brain ingress of regulatory T cells in a murine model of HIV-1 encephalitis
    • 10.1016/j.jneuroim.2010.08.014 20846730 10.1016/j.jneuroim.2010.08.014 1:CAS:528:DC%2BC3MXntVahtg%3D%3D 3003943
    • Gong N, Liu J, Reynolds AD, Gorantla S, Mosley RL, Gendelman HE (2011) Brain ingress of regulatory T cells in a murine model of HIV-1 encephalitis. J Neuroimmunol 230(1-2):33-41. doi: 10.1016/j.jneuroim.2010.08.014
    • (2011) J Neuroimmunol , vol.230 , Issue.1-2 , pp. 33-41
    • Gong, N.1    Liu, J.2    Reynolds, A.D.3    Gorantla, S.4    Mosley, R.L.5    Gendelman, H.E.6
  • 21
    • 78650217622 scopus 로고    scopus 로고
    • Links between progressive HIV-1 infection of humanized mice and viral neuropathogenesis
    • 10.2353/ajpath.2010.100536 21088215 10.2353/ajpath.2010.100536 1:CAS:528:DC%2BC3MXis1GqsA%3D%3D 2993281
    • Gorantla S, Makarov E, Finke-Dwyer J, Castanedo A, Holguin A, Gebhart CL, Gendelman HE, Poluektova L (2010a) Links between progressive HIV-1 infection of humanized mice and viral neuropathogenesis. Am J Pathol 177(6):2938-2949. doi: 10.2353/ajpath.2010.100536
    • (2010) Am J Pathol , vol.177 , Issue.6 , pp. 2938-2949
    • Gorantla, S.1    Makarov, E.2    Finke-Dwyer, J.3    Castanedo, A.4    Holguin, A.5    Gebhart, C.L.6    Gendelman, H.E.7    Poluektova, L.8
  • 23
    • 84857690625 scopus 로고    scopus 로고
    • Rodent models for HIV-associated neurocognitive disorders
    • 10.1016/j.tins.2011.12.006 22305769 10.1016/j.tins.2011.12.006 1:CAS:528:DC%2BC38Xjt1Oqtb0%3D 3294256
    • Gorantla S, Poluektova L, Gendelman HE (2012) Rodent models for HIV-associated neurocognitive disorders. Trends Neurosci 35(3):197-208. doi: 10.1016/j.tins.2011.12.006
    • (2012) Trends Neurosci , vol.35 , Issue.3 , pp. 197-208
    • Gorantla, S.1    Poluektova, L.2    Gendelman, H.E.3
  • 24
    • 0034099574 scopus 로고    scopus 로고
    • Proton NMR chemical shifts and coupling constants for brain metabolites
    • 10861994 10.1002/1099-1492(200005)13:3<129: AID-NBM619>3.0.CO;2-V 1:CAS:528:DC%2BD3cXksFSgtL8%3D
    • Govindaraju V, Young K, Maudsley AA (2000) Proton NMR chemical shifts and coupling constants for brain metabolites. NMR Biomed 13(3):129-153
    • (2000) NMR Biomed , vol.13 , Issue.3 , pp. 129-153
    • Govindaraju, V.1    Young, K.2    Maudsley, A.A.3
  • 26
    • 0020144785 scopus 로고
    • The use of high-energy microwave irradiation to inactivate mitochondrial enzymes
    • 6287883 10.1016/0003-2697(82)90621-2 1:CAS:528:DyaL38Xlt1egurY%3D
    • Hampson RK, Medina MA, Olson MS (1982) The use of high-energy microwave irradiation to inactivate mitochondrial enzymes. Anal Biochem 123(1):49-54
    • (1982) Anal Biochem , vol.123 , Issue.1 , pp. 49-54
    • Hampson, R.K.1    Medina, M.A.2    Olson, M.S.3
  • 27
    • 84863672520 scopus 로고    scopus 로고
    • Neuroimaging studies of the aging HIV-1-infected brain
    • 10.1007/s13365-012-0114-1 22653528 10.1007/s13365-012-0114-1 1:CAS:528:DC%2BC38XotlKntr0%3D
    • Holt JL, Kraft-Terry SD, Chang L (2012) Neuroimaging studies of the aging HIV-1-infected brain. Journal of neurovirology 18(4):291-302. doi: 10.1007/s13365-012-0114-1
    • (2012) Journal of Neurovirology , vol.18 , Issue.4 , pp. 291-302
    • Holt, J.L.1    Kraft-Terry, S.D.2    Chang, L.3
  • 28
    • 66849091880 scopus 로고    scopus 로고
    • Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex
    • 10.1111/j.1365-2249.2009.03933.x 19659776 10.1111/j.1365-2249.2009.03933. x 1:CAS:528:DC%2BD1MXos1Ojurs%3D 2710598
    • King MA, Covassin L, Brehm MA, Racki W, Pearson T, Leif J, Laning J, Fodor W, Foreman O, Burzenski L, Chase TH, Gott B, Rossini AA, Bortell R, Shultz LD, Greiner DL (2009) Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex. Clin Exp Immunol 157(1):104-118. doi: 10.1111/j.1365-2249.2009.03933.x
    • (2009) Clin Exp Immunol , vol.157 , Issue.1 , pp. 104-118
    • King, M.A.1    Covassin, L.2    Brehm, M.A.3    Racki, W.4    Pearson, T.5    Leif, J.6    Laning, J.7    Fodor, W.8    Foreman, O.9    Burzenski, L.10    Chase, T.H.11    Gott, B.12    Rossini, A.A.13    Bortell, R.14    Shultz, L.D.15    Greiner, D.L.16
  • 30
    • 70349810685 scopus 로고    scopus 로고
    • A coat of many colors: Neuroimmune crosstalk in human immunodeficiency virus infection
    • 10.1016/j.neuron.2009.09.042 19840555 10.1016/j.neuron.2009.09.042 1:CAS:528:DC%2BD1MXhsFajsbbI 2784686
    • Kraft-Terry SD, Buch SJ, Fox HS, Gendelman HE (2009) A coat of many colors: neuroimmune crosstalk in human immunodeficiency virus infection. Neuron 64(1):133-145. doi: 10.1016/j.neuron.2009.09.042
    • (2009) Neuron , vol.64 , Issue.1 , pp. 133-145
    • Kraft-Terry, S.D.1    Buch, S.J.2    Fox, H.S.3    Gendelman, H.E.4
  • 33
    • 0031871458 scopus 로고    scopus 로고
    • Calibration and standardization of microwave ovens for fixation of brain and peripheral nerve tissue
    • 10.1006/meth.1998.0613 9654457 10.1006/meth.1998.0613 1:CAS:528:DyaK1cXkvFamsrY%3D
    • Login GR, Leonard JB, Dvorak AM (1998) Calibration and standardization of microwave ovens for fixation of brain and peripheral nerve tissue. Methods 15(2):107-117. doi: 10.1006/meth.1998.0613
    • (1998) Methods , vol.15 , Issue.2 , pp. 107-117
    • Login, G.R.1    Leonard, J.B.2    Dvorak, A.M.3
  • 34
    • 84865054287 scopus 로고    scopus 로고
    • Developmental alterations in motor coordination and medium spiny neuron markers in mice lacking pgc-1alpha
    • 10.1371/journal.pone.0042878 22916173 10.1371/journal.pone.0042878 1:CAS:528:DC%2BC38Xht1ejt7nO 3419240
    • Lucas EK, Dougherty SE, McMeekin LJ, Trinh AT, Reid CS, Cowell RM (2012) Developmental alterations in motor coordination and medium spiny neuron markers in mice lacking pgc-1alpha. PLoS One 7(8):e42878. doi: 10.1371/journal.pone. 0042878
    • (2012) PLoS One , vol.7 , Issue.8 , pp. 42878
    • Lucas, E.K.1    Dougherty, S.E.2    McMeekin, L.J.3    Trinh, A.T.4    Reid, C.S.5    Cowell, R.M.6
  • 35
    • 79953696557 scopus 로고    scopus 로고
    • Statistical integration of 1H NMR and MRS data from different biofluids and tissues enhances recovery of biological information from individuals with HIV-1 infection
    • 10.1021/pr1010263 21244037 10.1021/pr1010263 1:CAS:528: DC%2BC3MXit1ygt7s%3D
    • Maher AD, Cysique LA, Brew BJ, Rae CD (2011) Statistical integration of 1H NMR and MRS data from different biofluids and tissues enhances recovery of biological information from individuals with HIV-1 infection. Journal of proteome research 10(4):1737-1745. doi: 10.1021/pr1010263
    • (2011) Journal of Proteome Research , vol.10 , Issue.4 , pp. 1737-1745
    • Maher, A.D.1    Cysique, L.A.2    Brew, B.J.3    Rae, C.D.4
  • 36
    • 84855481293 scopus 로고    scopus 로고
    • Early alterations of brain cellular energy homeostasis in Huntington disease models
    • 10.1074/jbc.M111.309849 22123819 10.1074/jbc.M111.309849 1:CAS:528:DC%2BC38XjslyltQ%3D%3D 3256882
    • Mochel F, Durant B, Meng X, O'Callaghan J, Yu H, Brouillet E, Wheeler VC, Humbert S, Schiffmann R, Durr A (2012) Early alterations of brain cellular energy homeostasis in Huntington disease models. J Biol Chem 287(2):1361-1370. doi: 10.1074/jbc.M111.309849
    • (2012) J Biol Chem , vol.287 , Issue.2 , pp. 1361-1370
    • Mochel, F.1    Durant, B.2    Meng, X.3    O'Callaghan, J.4    Yu, H.5    Brouillet, E.6    Wheeler, V.C.7    Humbert, S.8    Schiffmann, R.9    Durr, A.10
  • 39
    • 84857195689 scopus 로고    scopus 로고
    • Metabolomics implicates altered sphingolipids in chronic pain of neuropathic origin
    • 10.1038/nchembio.767 22267119 10.1038/nchembio.767 1:CAS:528: DC%2BC38XhtVGqsbg%3D 3567618
    • Patti GJ, Yanes O, Shriver LP, Courade JP, Tautenhahn R, Manchester M, Siuzdak G (2012) Metabolomics implicates altered sphingolipids in chronic pain of neuropathic origin. Nat Chem Biol 8(3):232-234. doi: 10.1038/nchembio.767
    • (2012) Nat Chem Biol , vol.8 , Issue.3 , pp. 232-234
    • Patti, G.J.1    Yanes, O.2    Shriver, L.P.3    Courade, J.P.4    Tautenhahn, R.5    Manchester, M.6    Siuzdak, G.7
  • 40
    • 0033226834 scopus 로고    scopus 로고
    • Toward an in vivo neurochemical profile: Quantification of 18 metabolites in short-echo-time (1)H NMR spectra of the rat brain
    • 10.1006/jmre.1999.1895 10527748 10.1006/jmre.1999.1895 1:CAS:528:DyaK1MXms1Kntr8%3D
    • Pfeuffer J, Tkac I, Provencher SW, Gruetter R (1999) Toward an in vivo neurochemical profile: quantification of 18 metabolites in short-echo-time (1)H NMR spectra of the rat brain. J Magn Reson 141(1):104-120. doi: 10.1006/jmre.1999.1895
    • (1999) J Magn Reson , vol.141 , Issue.1 , pp. 104-120
    • Pfeuffer, J.1    Tkac, I.2    Provencher, S.W.3    Gruetter, R.4
  • 42
    • 14844292113 scopus 로고    scopus 로고
    • Time-domain semi-parametric estimation based on a metabolite basis set
    • 10.1002/nbm.895 15660450 10.1002/nbm.895 1:CAS:528:DC%2BD2MXis1Wlt7o%3D
    • Ratiney H, Sdika M, Coenradie Y, Cavassila S, van Ormondt D, Graveron-Demilly D (2005) Time-domain semi-parametric estimation based on a metabolite basis set. NMR Biomed 18(1):1-13. doi: 10.1002/nbm.895
    • (2005) NMR Biomed , vol.18 , Issue.1 , pp. 1-13
    • Ratiney, H.1    Sdika, M.2    Coenradie, Y.3    Cavassila, S.4    Van Ormondt, D.5    Graveron-Demilly, D.6
  • 44
    • 36349014934 scopus 로고    scopus 로고
    • Cerebrospinal fluid proteomic profiling of HIV-1-infected patients with cognitive impairment
    • 10.1021/pr070220c 10.1021/pr070220c 1:CAS:528:DC%2BD2sXhtFGisrnK
    • Rozek W, Ricardo-Dukelow M, Holloway S, Gendelman HE, Wojna V, Melendez LM, Ciborowski P (2007) Cerebrospinal fluid proteomic profiling of HIV-1-infected patients with cognitive impairment. J Prot Res 6(11):4189-4199. doi: 10.1021/pr070220c
    • (2007) J Prot Res , vol.6 , Issue.11 , pp. 4189-4199
    • Rozek, W.1    Ricardo-Dukelow, M.2    Holloway, S.3    Gendelman, H.E.4    Wojna, V.5    Melendez, L.M.6    Ciborowski, P.7
  • 45
    • 84855995732 scopus 로고    scopus 로고
    • Central metabolite changes and activation of microglia after peripheral interleukin-2 challenge
    • 10.1016/j.bbi.2011.09.011 21983278 10.1016/j.bbi.2011.09.011 1:CAS:528:DC%2BC38Xht1yqtLo%3D
    • Schneider P, Weber-Fahr W, Schweinfurth N, Ho YJ, Sartorius A, Spanagel R, Pawlak CR (2012) Central metabolite changes and activation of microglia after peripheral interleukin-2 challenge. Brain Behav Immun 26(2):277-283. doi: 10.1016/j.bbi.2011.09.011
    • (2012) Brain Behav Immun , vol.26 , Issue.2 , pp. 277-283
    • Schneider, P.1    Weber-Fahr, W.2    Schweinfurth, N.3    Ho, Y.J.4    Sartorius, A.5    Spanagel, R.6    Pawlak, C.R.7
  • 47
    • 0001876029 scopus 로고
    • Computer simulations in magnetic resonance. An object-oriented programming approach
    • 10.1006/jmra.1994.1008 10.1006/jmra.1994.1008 1:CAS:528: DyaK2cXhvVWgs7w%3D
    • Smith SA, Levante TO, Meier BH, Ernst RR (1994) Computer Simulations in Magnetic Resonance. An Object-Oriented Programming Approach. J Magnet Reson, Series A 106(1):75-105. doi: 10.1006/jmra.1994.1008
    • (1994) J Magnet Reson, Series A , vol.106 , Issue.1 , pp. 75-105
    • Smith, S.A.1    Levante, T.O.2    Meier, B.H.3    Ernst, R.R.4
  • 51
    • 58149475955 scopus 로고    scopus 로고
    • Antioxidant enzyme dysfunction in monocytes and CSF of Hispanic women with HIV-associated cognitive impairment
    • 10.1016/j.jneuroim.2008.10.013 19101040 10.1016/j.jneuroim.2008.10.013 1:CAS:528:DC%2BD1MXktlClsg%3D%3D 2947717
    • Velazquez I, Plaud M, Wojna V, Skolasky R, Laspiur JP, Melendez LM (2009) Antioxidant enzyme dysfunction in monocytes and CSF of Hispanic women with HIV-associated cognitive impairment. J Neuroimmunol 206(1-2):106-111. doi: 10.1016/j.jneuroim.2008.10.013
    • (2009) J Neuroimmunol , vol.206 , Issue.1-2 , pp. 106-111
    • Velazquez, I.1    Plaud, M.2    Wojna, V.3    Skolasky, R.4    Laspiur, J.P.5    Melendez, L.M.6
  • 52
    • 46749146517 scopus 로고    scopus 로고
    • Metabolomic analysis of the cerebrospinal fluid reveals changes in phospholipase expression in the CNS of SIV-infected macaques
    • 10.1172/JCI34138 18521184 1:CAS:528:DC%2BD1cXot1Omsr4%3D 2398736
    • Wikoff WR, Pendyala G, Siuzdak G, Fox HS (2008) Metabolomic analysis of the cerebrospinal fluid reveals changes in phospholipase expression in the CNS of SIV-infected macaques. J Clin Invest 118(7):2661-2669. doi: 10.1172/JCI34138
    • (2008) J Clin Invest , vol.118 , Issue.7 , pp. 2661-2669
    • Wikoff, W.R.1    Pendyala, G.2    Siuzdak, G.3    Fox, H.S.4
  • 54
    • 79960839794 scopus 로고    scopus 로고
    • Metabolomics analysis reveals elevation of 3-indoxyl sulfate in plasma and brain during chemically-induced acute kidney injury in mice: Investigation of nicotinic acid receptor agonists
    • 10.1016/j.taap.2011.05.015 21640743 10.1016/j.taap.2011.05.015 1:CAS:528:DC%2BC3MXpsFKgsb0%3D
    • Zgoda-Pols JR, Chowdhury S, Wirth M, Milburn MV, Alexander DC, Alton KB (2011) Metabolomics analysis reveals elevation of 3-indoxyl sulfate in plasma and brain during chemically-induced acute kidney injury in mice: Investigation of nicotinic acid receptor agonists. Toxicol Appl Pharmacol 255(1):48-56. doi: 10.1016/j.taap.2011.05.015
    • (2011) Toxicol Appl Pharmacol , vol.255 , Issue.1 , pp. 48-56
    • Zgoda-Pols, J.R.1    Chowdhury, S.2    Wirth, M.3    Milburn, M.V.4    Alexander, D.C.5    Alton, K.B.6


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