메뉴 건너뛰기




Volumn 177, Issue 6, 2010, Pages 2938-2949

Links between progressive HIV-1 infection of humanized mice and viral neuropathogenesis

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; DISEASE COURSE; ENCEPHALITIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MACROPHAGE; MOUSE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; T CELL DEPLETION;

EID: 78650217622     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.100536     Document Type: Article
Times cited : (82)

References (90)
  • 2
    • 0031447215 scopus 로고    scopus 로고
    • An analysis of HIV-1-associated inflammatory products in brain tissue of humans and SCID mice with HIV-1 encephalitis
    • Persidsky Y, Buttini M, Limoges J, Bock P, Gendelman HE: An analysis of HIV-1-associated inflammatory products in brain tissue of humans and SCID mice with HIV-1 encephalitis. J Neurovirol 1997, 3:401-416
    • (1997) J Neurovirol , vol.3 , pp. 401-416
    • Persidsky, Y.1    Buttini, M.2    Limoges, J.3    Bock, P.4    Gendelman, H.E.5
  • 3
    • 0037090141 scopus 로고    scopus 로고
    • Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis
    • Poluektova LY, Munn DH, Persidsky Y, Gendelman HE: Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis. J Immunol 2002, 168:3941-3949
    • (2002) J Immunol , vol.168 , pp. 3941-3949
    • Poluektova, L.Y.1    Munn, D.H.2    Persidsky, Y.3    Gendelman, H.E.4
  • 4
    • 2942615005 scopus 로고    scopus 로고
    • Neuroregulatory events follow adaptive immune-mediated elimination of HIV-1-infected macrophages: Studies in a murine model of viral encephalitis
    • Poluektova L, Gorantla S, Faraci J, Birusingh K, Dou H, Gendelman HE: Neuroregulatory events follow adaptive immune-mediated elimination of HIV-1-infected macrophages: studies in a murine model of viral encephalitis. J Immunol 2004, 172:7610-7617 (Pubitemid 38747625)
    • (2004) Journal of Immunology , vol.172 , Issue.12 , pp. 7610-7617
    • Poluektova, L.1    Gorantla, S.2    Faraci, J.3    Birusingh, K.4    Dou, H.5    Gendelman, H.E.6
  • 6
    • 30444434294 scopus 로고    scopus 로고
    • Macrophage-induced inflammation affects hippocampal plasticity and neuronal development in a murine model of HIV-1 encephalitis
    • Poluektova L, Meyer V, Walters L, Paez X, Gendelman HE: Macrophage-induced inflammation affects hippocampal plasticity and neuronal development in a murine model of HIV-1 encephalitis. Glia 2005, 52:344-353
    • (2005) Glia , vol.52 , pp. 344-353
    • Poluektova, L.1    Meyer, V.2    Walters, L.3    Paez, X.4    Gendelman, H.E.5
  • 9
    • 36349028152 scopus 로고    scopus 로고
    • Humanized NOD/SCID/IL2R{gamma}null mice transplanted with hematopoietic stem cells under nonmyeloablative conditions show prolonged life spans and allow detailed analysis of human immunodeficiency virus type 1 pathogenesis
    • Watanabe S, Ohta S, Yajima M, Terashima K, Ito M, Mugishima H, Fujiwara S, Shimizu K, Honda M, Shimizu N, Yamamoto N: Humanized NOD/SCID/IL2R{gamma}null mice transplanted with hematopoietic stem cells under nonmyeloablative conditions show prolonged life spans and allow detailed analysis of human immunodeficiency virus type 1 pathogenesis. J Virol 2007, 81:13259-13264
    • (2007) J Virol , vol.81 , pp. 13259-13264
    • Watanabe, S.1    Ohta, S.2    Yajima, M.3    Terashima, K.4    Ito, M.5    Mugishima, H.6    Fujiwara, S.7    Shimizu, K.8    Honda, M.9    Shimizu, N.10    Yamamoto, N.11
  • 13
    • 40849104785 scopus 로고    scopus 로고
    • Mucosal transmission of R5 and X4 tropic HIV-1 via vaginal and rectal routes in humanized Rag2-/- gammac -/- (RAG-hu) mice
    • Berges B, Akkina S, Folkvord J, Connick E, Akkina R: Mucosal transmission of R5 and X4 tropic HIV-1 via vaginal and rectal routes in humanized Rag2-/- gammac -/- (RAG-hu) mice. Virology 2008, 373:342-351
    • (2008) Virology , vol.373 , pp. 342-351
    • Berges, B.1    Akkina, S.2    Folkvord, J.3    Connick, E.4    Akkina, R.5
  • 14
    • 34248335883 scopus 로고    scopus 로고
    • Use of a novel chimeric mouse model with a functionally active human immune system to study human immunodeficiency virus type 1 infection
    • An DS, Poon B, Fang RH, Weijer K, Blom B, Spits H, Chen IS, Uittenbogaart CH: Use of a novel chimeric mouse model with a functionally active human immune system to study human immunodeficiency virus type 1 infection. Clin Vaccine Immunol 2007, 14:391-396
    • (2007) Clin Vaccine Immunol , vol.14 , pp. 391-396
    • An, D.S.1    Poon, B.2    Fang, R.H.3    Weijer, K.4    Blom, B.5    Spits, H.6    Chen, I.S.7    Uittenbogaart, C.H.8
  • 15
    • 33947596455 scopus 로고    scopus 로고
    • HIV-1 infection and pathogenesis in a novel humanized mouse model
    • DOI 10.1182/blood-2006-07-033159
    • Zhang L, Kovalev GI, Su L: HIV-1 infection and pathogenesis in a novel humanized mouse model. Blood 2007, 109:2978-2981 (Pubitemid 46482096)
    • (2007) Blood , vol.109 , Issue.7 , pp. 2978-2981
    • Zhang, L.1    Kovalev, G.I.2    Su, L.3
  • 18
    • 39149143342 scopus 로고    scopus 로고
    • Immune activation of the central nervous system is still present after >4 years of effective highly active antiretroviral therapy
    • Eden A, Price RW, Spudich S, Fuchs D, Hagberg L, Gisslen M: Immune activation of the central nervous system is still present after >4 years of effective highly active antiretroviral therapy. J Infect Dis 2007, 196:1779-1783
    • (2007) J Infect Dis , vol.196 , pp. 1779-1783
    • Eden, A.1    Price, R.W.2    Spudich, S.3    Fuchs, D.4    Hagberg, L.5    Gisslen, M.6
  • 19
    • 54249162813 scopus 로고    scopus 로고
    • HIV-associated neurocognitive disease continues in the antiretroviral era
    • Clifford DB: HIV-associated neurocognitive disease continues in the antiretroviral era. Top HIV Med 2008, 16:94-98
    • (2008) Top HIV Med , vol.16 , pp. 94-98
    • Clifford, D.B.1
  • 20
    • 33846923131 scopus 로고    scopus 로고
    • Dementia and neurocognitive disorders due to HIV-1 infection
    • DOI 10.1055/s-2006-956759
    • Ances BM, Ellis RJ: Dementia and neurocognitive disorders due to HIV-1 infection. Semin Neurol 2007, 27:86-92 (Pubitemid 46239043)
    • (2007) Seminars in Neurology , vol.27 , Issue.1 , pp. 86-92
    • Ances, B.M.1    Ellis, R.J.2
  • 21
    • 34447540064 scopus 로고    scopus 로고
    • Neurologic complications of HIV disease and their treatment
    • Letendre S, Ances B, Gibson S, Ellis RJ: Neurologic complications of HIV disease and their treatment. Top HIV Med 2007, 15:32-39
    • (2007) Top HIV Med , vol.15 , pp. 32-39
    • Letendre, S.1    Ances, B.2    Gibson, S.3    Ellis, R.J.4
  • 22
    • 29144494827 scopus 로고    scopus 로고
    • Regulation of neural cell survival by HIV-1 infection
    • Jones G, Power C: Regulation of neural cell survival by HIV-1 infection. Neurobiol Dis 2006, 21:1-17
    • (2006) Neurobiol Dis , vol.21 , pp. 1-17
    • Jones, G.1    Power, C.2
  • 27
    • 70349810685 scopus 로고    scopus 로고
    • A coat of many colors: Neuroimmune crosstalk in human immunodeficiency virus infection
    • Kraft-Terry SD, Buch SJ, Fox HS, Gendelman HE: A coat of many colors: neuroimmune crosstalk in human immunodeficiency virus infection. Neuron 2009, 64:133-145
    • (2009) Neuron , vol.64 , pp. 133-145
    • Kraft-Terry, S.D.1    Buch, S.J.2    Fox, H.S.3    Gendelman, H.E.4
  • 29
    • 0029859515 scopus 로고    scopus 로고
    • HIV-1 DNA in brains in AIDS and pre-AIDS: Correlation with the stage of disease
    • An SF, Giometto B, Scaravilli F: HIV-1 DNA in brains in AIDS and pre-AIDS: correlation with the stage of disease. Ann Neurol 1996, 40:611-617
    • (1996) Ann Neurol , vol.40 , pp. 611-617
    • An, S.F.1    Giometto, B.2    Scaravilli, F.3
  • 32
    • 0031774155 scopus 로고    scopus 로고
    • Protective role of the virusspecific immune response for development of severe neurologic signs in simian immunodeficiency virus-infected macaques
    • Sopper S, Sauer U, Hemm S, Demuth M, Muller J, Stahl-Hennig C, Hunsmann G, ter Meulen V, Dorries R: Protective role of the virusspecific immune response for development of severe neurologic signs in simian immunodeficiency virus-infected macaques. J Virol 1998, 72:9940-9947
    • (1998) J Virol , vol.72 , pp. 9940-9947
    • Sopper, S.1    Sauer, U.2    Hemm, S.3    Demuth, M.4    Muller, J.5    Stahl-Hennig, C.6    Hunsmann, G.7    Ter Meulen, V.8    Dorries, R.9
  • 34
    • 33646524301 scopus 로고    scopus 로고
    • Longitudinal analysis of monocyte/macrophage infection in simian immunodeficiency virus-infected. CD8+ T-cell-depleted macaques that develop lentiviral encephalitis
    • Bissel SJ, Wang G, Trichel AM, Murphey-Corb M, Wiley CA: Longitudinal analysis of monocyte/macrophage infection in simian immunodeficiency virus-infected. CD8+ T-cell-depleted macaques that develop lentiviral encephalitis. Am J Pathol 2006, 168:1553-1569
    • (2006) Am J Pathol , vol.168 , pp. 1553-1569
    • Bissel, S.J.1    Wang, G.2    Trichel, A.M.3    Murphey-Corb, M.4    Wiley, C.A.5
  • 37
    • 0031985775 scopus 로고    scopus 로고
    • Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques
    • Matano T, Shibata R, Siemon C, Connors M, Lane HC, Martin MA: Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques. J Virol 1998, 72:164-169
    • (1998) J Virol , vol.72 , pp. 164-169
    • Matano, T.1    Shibata, R.2    Siemon, C.3    Connors, M.4    Lane, H.C.5    Martin, M.A.6
  • 38
    • 55249089046 scopus 로고    scopus 로고
    • Enhancement of human immunodeficiency virus (HIV)-specific CD8+ T cells in cerebrospinal fluid compared to those in blood among antiretroviral therapy-naive HIV-positive subjects
    • Sadagopal S, Lorey SL, Barnett L, Basham R, Lebo L, Erdem H, Haman K, Avison M, Waddell K, Haas DW, Kalams SA: Enhancement of human immunodeficiency virus (HIV)-specific CD8+ T cells in cerebrospinal fluid compared to those in blood among antiretroviral therapy-naive HIV-positive subjects. J Virol 2008, 82:10418-10428
    • (2008) J Virol , vol.82 , pp. 10418-10428
    • Sadagopal, S.1    Lorey, S.L.2    Barnett, L.3    Basham, R.4    Lebo, L.5    Erdem, H.6    Haman, K.7    Avison, M.8    Waddell, K.9    Haas, D.W.10    Kalams, S.A.11
  • 39
    • 0027474068 scopus 로고
    • In vivo expression of inducible nitric oxide synthase in experimentally induced neurologic diseases
    • published erratum appears in Proc Natl Acad Sci USA: 1993 Jun 1;90(11):5378
    • Koprowski H, Zheng YM, Heber-Katz E, Fraser N, Rorke L, Fu ZF, Hanlon C, Dietzschold B: In vivo expression of inducible nitric oxide synthase in experimentally induced neurologic diseases [published erratum appears in Proc Natl Acad Sci USA: 1993 Jun 1;90(11):5378]. Proc Natl Acad Sci USA 1993, 90:3024-3027
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3024-3027
    • Koprowski, H.1    Zheng, Y.M.2    Heber-Katz, E.3    Fraser, N.4    Rorke, L.5    Fu, Z.F.6    Hanlon, C.7    Dietzschold, B.8
  • 40
    • 0032930126 scopus 로고    scopus 로고
    • Rate and severity of HIV-associated dementia (HAD): Correlations with Gp41 and iNOS
    • Adamson DC, McArthur JC, Dawson TM, Dawson VL: Rate and severity of HIV-associated dementia (HAD): correlations with Gp41 and iNOS. Mol Med 1999, 5:98-109
    • (1999) Mol Med , vol.5 , pp. 98-109
    • Adamson, D.C.1    McArthur, J.C.2    Dawson, T.M.3    Dawson, V.L.4
  • 41
    • 0029669179 scopus 로고    scopus 로고
    • Expression of inflammatory cytokines and inducible nitric oxide synthase in brains of SIV-infected rhesus monkeys: Applications to HIV-induced central nervous system disease
    • Lane TE, Buchmeier MJ, Watry DD, Fox HS: Expression of inflammatory cytokines and inducible nitric oxide synthase in brains of SIVinfected rhesus monkeys: applications to HIV-induced central nervous system disease. Mol Med 1996, 2:27-37 (Pubitemid 3037403)
    • (1996) Molecular Medicine , vol.2 , Issue.1 , pp. 27-37
    • Lane, T.E.1    Buchmeier, M.J.2    Watry, D.D.3    Fox, H.S.4
  • 42
    • 0029833018 scopus 로고    scopus 로고
    • AIDS dementia is associated with massive, activated HIV-1 infection and concomitant expression of several cytokines
    • Nuovo G, Alfieri M: AIDS dementia is associated with massive, activated HIV-1 infection and concomitant expression of several cytokines. Mol Med 1996, 2:358-366
    • (1996) Mol Med , vol.2 , pp. 358-366
    • Nuovo, G.1    Alfieri, M.2
  • 43
    • 0033559312 scopus 로고    scopus 로고
    • Human immunodeficiency virus-1-infected macrophages induce inducible nitric oxide synthase and nitric oxide (NO) production in astrocytes: Astrocytic NO as a possible mediator of neural damage in acquired immunodeficiency syndrome
    • Hori K, Burd PR, Furuke K, Kutza J, Weih KA, Clouse KA: Human immunodeficiency virus-1-infected macrophages induce inducible nitric oxide synthase and nitric oxide (NO) production in astrocytes: astrocytic NO as a possible mediator of neural damage in acquired immunodeficiency syndrome. Blood 1999, 93:1843-1850
    • (1999) Blood , vol.93 , pp. 1843-1850
    • Hori, K.1    Burd, P.R.2    Furuke, K.3    Kutza, J.4    Weih, K.A.5    Clouse, K.A.6
  • 55
    • 60749126977 scopus 로고    scopus 로고
    • Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for molecules associated with metabolism, signaling and regulation in central nervous system mixed glial cell cultures
    • Lisak RP, Benjamins JA, Bealmear B, Nedelkoska L, Studzinski D, Retland E, Yao B, Land S: Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for molecules associated with metabolism, signaling and regulation in central nervous system mixed glial cell cultures. J Neuroinflammation 2009, 6:4
    • (2009) J Neuroinflammation , vol.6 , pp. 4
    • Lisak, R.P.1    Benjamins, J.A.2    Bealmear, B.3    Nedelkoska, L.4    Studzinski, D.5    Retland, E.6    Yao, B.7    Land, S.8
  • 56
    • 0028966205 scopus 로고
    • Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: Implications for HIV- associated neurological disease
    • Bukrinsky MI, Nottet HS, Schmidtmayerova H, Dubrovsky L, Flanagan CR, Mullins ME, Lipton SA, Gendelman HE: Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV- associated neurological disease. J Exp Med 1995, 181:735-745
    • (1995) J Exp Med , vol.181 , pp. 735-745
    • Bukrinsky, M.I.1    Nottet, H.S.2    Schmidtmayerova, H.3    Dubrovsky, L.4    Flanagan, C.R.5    Mullins, M.E.6    Lipton, S.A.7    Gendelman, H.E.8
  • 58
    • 36749005178 scopus 로고    scopus 로고
    • Mechanisms of inflammatory neurodegeneration: INOS and NADPH oxidase
    • Brown GC: Mechanisms of inflammatory neurodegeneration: iNOS and NADPH oxidase. Biochem Soc Trans 2007, 35:1119-1121
    • (2007) Biochem Soc Trans , vol.35 , pp. 1119-1121
    • Brown, G.C.1
  • 59
    • 55749111902 scopus 로고    scopus 로고
    • Blood-brain barrier changes and cell invasion differ between therapeutic immune clearance of neurotrophic virus and CNS autoimmunity
    • Fabis MJ, Phares TW, Kean RB, Koprowski H, Hooper DC: Blood-brain barrier changes and cell invasion differ between therapeutic immune clearance of neurotrophic virus and CNS autoimmunity. Proc Natl Acad Sci USA 2008, 105:15511-15516
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 15511-15516
    • Fabis, M.J.1    Phares, T.W.2    Kean, R.B.3    Koprowski, H.4    Hooper, D.C.5
  • 60
    • 33744905805 scopus 로고    scopus 로고
    • Regional Differences in Blood-Brain Barrier Permeability Changes and Inflammation in the Apathogenic Clearance of Virus from the Central Nervous System
    • Phares TW, Kean RB, Mikheeva T, Hooper DC: Regional Differences in Blood-Brain Barrier Permeability Changes and Inflammation in the Apathogenic Clearance of Virus from the Central Nervous System. J Immunol 2006, 176:7666-7675
    • (2006) J Immunol , vol.176 , pp. 7666-7675
    • Phares, T.W.1    Kean, R.B.2    Mikheeva, T.3    Hooper, D.C.4
  • 61
    • 0030922857 scopus 로고    scopus 로고
    • Early HIV-1 infection of the central nervous system
    • An SF, Scaravilli F: Early HIV-1 infection of the central nervous system. Arch Anat Cytol Pathol 1997, 45:94-105
    • (1997) Arch Anat Cytol Pathol , vol.45 , pp. 94-105
    • An, S.F.1    Scaravilli, F.2
  • 65
    • 1542285311 scopus 로고    scopus 로고
    • Levels of human immunodeficiency virus type 1 (HIV-1) replication in macrophages determines the severity of murine HIV-1 encephalitis
    • Nukuna A, Gendelman HE, Limoges J, Rasmussen J, Poluektova L, Ghorpade A, Persidsky Y: Levels of human immunodeficiency virus type 1 (HIV-1) replication in macrophages determines the severity of murine HIV-1 encephalitis. J Neurovirol 2004, 10 Suppl 1:82-90
    • (2004) J Neurovirol , vol.10 , Issue.SUPPL. 1 , pp. 82-90
    • Nukuna, A.1    Gendelman, H.E.2    Limoges, J.3    Rasmussen, J.4    Poluektova, L.5    Ghorpade, A.6    Persidsky, Y.7
  • 66
    • 33749035469 scopus 로고    scopus 로고
    • HIV-1-infected and/or immune activated macophages regulate astrocyte SDF-1 production through IL-1beta
    • Peng H, Erdmann N, Whitney N, Dou H, Gorantla S, Gendelman HE, Ghorpade A, Zheng J: HIV-1-infected and/or immune activated macophages regulate astrocyte SDF-1 production through IL-1beta. Glia 2006, 54:619-629
    • (2006) Glia , vol.54 , pp. 619-629
    • Peng, H.1    Erdmann, N.2    Whitney, N.3    Dou, H.4    Gorantla, S.5    Gendelman, H.E.6    Ghorpade, A.7    Zheng, J.8
  • 68
    • 0030922605 scopus 로고    scopus 로고
    • Dexamethasone therapy worsens the neuropathology of human immunodeficiency virus type 1 encephalitis in SCID mice
    • Limoges J, Persidsky Y, Bock P, Gendelman HE: Dexamethasone therapy worsens the neuropathology of human immunodeficiency virus type 1 encephalitis in SCID mice. J Infect Dis 1997, 175:1368-1381 (Pubitemid 27225040)
    • (1997) Journal of Infectious Diseases , vol.175 , Issue.6 , pp. 1368-1381
    • Limoges, J.1    Persidsky, Y.2    Bock, P.3    Gendelman, H.E.4
  • 70
    • 0033956427 scopus 로고    scopus 로고
    • Changes in pathological findings at autopsy in AIDS cases for the last 15 years
    • Masliah E, DeTeresa RM, Mallory ME, Hansen LA: Changes in pathological findings at autopsy in AIDS cases for the last 15 years. AIDS 2000, 14:69-74
    • (2000) AIDS , vol.14 , pp. 69-74
    • Masliah, E.1    DeTeresa, R.M.2    Mallory, M.E.3    Hansen, L.A.4
  • 71
    • 0024264066 scopus 로고
    • Human immunodeficiency virus type 1 (HIV-1) infection of the nervous system: A review
    • Michaels J, Sharer LR, Epstein LG: Human immunodeficiency virus type 1 (HIV-1) infection of the nervous system: a review. Immunodefic Rev 1988, 1:71-104
    • (1988) Immunodefic Rev , vol.1 , pp. 71-104
    • Michaels, J.1    Sharer, L.R.2    Epstein, L.G.3
  • 72
    • 0036744132 scopus 로고    scopus 로고
    • Acute meningoencephalitis as initial presentation of human immunodeficiency virus infection: Report of two cases
    • Li CM, Lee YY, Ho YR: Acute meningoencephalitis as initial presentation of human immunodeficiency virus infection: report of two cases. J Microbiol Immunol Infect 2002, 35:195-198
    • (2002) J Microbiol Immunol Infect , vol.35 , pp. 195-198
    • Li, C.M.1    Lee, Y.Y.2    Ho, Y.R.3
  • 73
    • 0018344553 scopus 로고
    • Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat
    • Barnes CA: Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. J Comp Physiol Psychol 1979, 93:74-104
    • (1979) J Comp Physiol Psychol , vol.93 , pp. 74-104
    • Barnes, C.A.1
  • 76
    • 0036258831 scopus 로고    scopus 로고
    • An assay for long-term engrafting human hematopoietic cells based on newborn NOD/SCID/beta2-microglobulin(null) mice
    • Ishikawa F, Livingston AG, Wingard JR, Nishikawa S, Ogawa M: An assay for long-term engrafting human hematopoietic cells based on newborn NOD/SCID/beta2-microglobulin(null) mice. Exp Hematol 2002, 30:488-494
    • (2002) Exp Hematol , vol.30 , pp. 488-494
    • Ishikawa, F.1    Livingston, A.G.2    Wingard, J.R.3    Nishikawa, S.4    Ogawa, M.5
  • 77
    • 36448992228 scopus 로고    scopus 로고
    • Efficient transplantation via antibody-based clearance of hematopoietic stem cell niches
    • DOI 10.1126/science.1149726
    • Czechowicz A, Kraft D, Weissman IL, Bhattacharya D: Efficient transplantation via antibody-based clearance of hematopoietic stem cell niches. Science 2007, 318:1296-1299 (Pubitemid 350172893)
    • (2007) Science , vol.318 , Issue.5854 , pp. 1296-1299
    • Czechowicz, A.1    Kraft, D.2    Weissman, I.L.3    Bhattacharya, D.4
  • 78
    • 0032530736 scopus 로고    scopus 로고
    • Elevated levels of serum-soluble CD14 in human immunodeficiency virus type 1 (HIV-1) infection: Correlation to disease progression and clinical events
    • Lien E, Aukrust P, Sundan A, Muller F, Froland SS, Espevik T: Elevated levels of serum-soluble CD14 in human immunodeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events. Blood 1998, 92:2084-2092
    • (1998) Blood , vol.92 , pp. 2084-2092
    • Lien, E.1    Aukrust, P.2    Sundan, A.3    Muller, F.4    Froland, S.S.5    Espevik, T.6
  • 79
    • 58149177783 scopus 로고    scopus 로고
    • Cutting edge: Experimentally induced immune activation in natural hosts of simian immunodeficiency virus induces significant increases in viral replication and CD4+ T cell depletion
    • Pandrea I, Gaufin T, Brenchley JM, Gautam R, Monjure C, Gautam A, Coleman C, Lackner AA, Ribeiro RM, Douek DC, Apetrei C: Cutting edge: experimentally induced immune activation in natural hosts of simian immunodeficiency virus induces significant increases in viral replication and CD4+ T cell depletion. J Immunol 2008, 181:6687-6691
    • (2008) J Immunol , vol.181 , pp. 6687-6691
    • Pandrea, I.1    Gaufin, T.2    Brenchley, J.M.3    Gautam, R.4    Monjure, C.5    Gautam, A.6    Coleman, C.7    Lackner, A.A.8    Ribeiro, R.M.9    Douek, D.C.10    Apetrei, C.11
  • 88
    • 33645453995 scopus 로고    scopus 로고
    • Alcohol Abuse Enhances Neuroinflammation and Impairs Immune Responses in an Animal Model of Human Immunodeficiency Virus-1 Encephalitis
    • Potula R, Haorah J, Knipe B, Leibhart J, Chrastil J, Heilman D, Dou H, Reddy R, Ghorpade A, Persidsky Y: Alcohol Abuse Enhances Neuroinflammation and Impairs Immune Responses in an Animal Model of Human Immunodeficiency Virus-1 Encephalitis. Am J Pathol 2006, 168:1335-1344
    • (2006) Am J Pathol , vol.168 , pp. 1335-1344
    • Potula, R.1    Haorah, J.2    Knipe, B.3    Leibhart, J.4    Chrastil, J.5    Heilman, D.6    Dou, H.7    Reddy, R.8    Ghorpade, A.9    Persidsky, Y.10
  • 89
    • 27144489077 scopus 로고    scopus 로고
    • Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis
    • Potula R, Poluektova L, Knipe B, Chrastil J, Heilman D, Dou H, Takikawa O, Munn DH, Gendelman HE, Persidsky Y: Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis. Blood 2005, 106:2382-2390
    • (2005) Blood , vol.106 , pp. 2382-2390
    • Potula, R.1    Poluektova, L.2    Knipe, B.3    Chrastil, J.4    Heilman, D.5    Dou, H.6    Takikawa, O.7    Munn, D.H.8    Gendelman, H.E.9    Persidsky, Y.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.