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Volumn 230, Issue 1-2, 2011, Pages 33-41

Brain ingress of regulatory T cells in a murine model of HIV-1 encephalitis

Author keywords

Blood brain barrier; CD4+CD25+ regulatory T cells; HIV 1; Macrophage; Neuroprotection; Single photon emission computed tomography

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; INDIUM 111;

EID: 78650966753     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2010.08.014     Document Type: Article
Times cited : (21)

References (61)
  • 2
    • 33845379986 scopus 로고    scopus 로고
    • Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients
    • Battaglia M., Stabilini A., Migliavacca B., Horejs-Hoeck J., Kaupper T., Roncarolo M.G. Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients. J. Immunol. 2006, 177:8338-8347.
    • (2006) J. Immunol. , vol.177 , pp. 8338-8347
    • Battaglia, M.1    Stabilini, A.2    Migliavacca, B.3    Horejs-Hoeck, J.4    Kaupper, T.5    Roncarolo, M.G.6
  • 5
    • 17144374934 scopus 로고    scopus 로고
    • Regulatory T-cell therapy: is it ready for the clinic
    • Bluestone J.A. Regulatory T-cell therapy: is it ready for the clinic? Nat. Rev. Immunol. 2005, 5:343-349.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 343-349
    • Bluestone, J.A.1
  • 6
    • 27144495833 scopus 로고    scopus 로고
    • How do CD4+CD25+ regulatory T cells control autoimmunity
    • Bluestone J.A., Tang Q. How do CD4+CD25+ regulatory T cells control autoimmunity? Curr. Opin. Immunol. 2005, 17:638-642.
    • (2005) Curr. Opin. Immunol. , vol.17 , pp. 638-642
    • Bluestone, J.A.1    Tang, Q.2
  • 8
    • 1942456867 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T-cell deficiency in patients with hepatitis C-mixed cryoglobulinemia vasculitis
    • Boyer O., Saadoun D., Abriol J., Dodille M., Piette J.C., Cacoub P., Klatzmann D. CD4+CD25+ regulatory T-cell deficiency in patients with hepatitis C-mixed cryoglobulinemia vasculitis. Blood 2004, 103:3428-3430.
    • (2004) Blood , vol.103 , pp. 3428-3430
    • Boyer, O.1    Saadoun, D.2    Abriol, J.3    Dodille, M.4    Piette, J.C.5    Cacoub, P.6    Klatzmann, D.7
  • 9
    • 33747465111 scopus 로고    scopus 로고
    • Neuroimmunity and the blood-brain barrier: molecular regulation of leukocyte transmigration and viral entry into the nervous system with a focus on neuroAIDS
    • Buckner C.M., Luers A.J., Calderon T.M., Eugenin E.A., Berman J.W. Neuroimmunity and the blood-brain barrier: molecular regulation of leukocyte transmigration and viral entry into the nervous system with a focus on neuroAIDS. J. Neuroimmune Pharmacol. 2006, 1:160-181.
    • (2006) J. Neuroimmune Pharmacol. , vol.1 , pp. 160-181
    • Buckner, C.M.1    Luers, A.J.2    Calderon, T.M.3    Eugenin, E.A.4    Berman, J.W.5
  • 10
    • 0043069555 scopus 로고    scopus 로고
    • Toxicity of antiretroviral therapy and implications for drug development
    • Carr A. Toxicity of antiretroviral therapy and implications for drug development. Nat. Rev. Drug Discov. 2003, 2:624-634.
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 624-634
    • Carr, A.1
  • 15
    • 23744475685 scopus 로고    scopus 로고
    • The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms
    • Engelhardt B., Ransohoff R.M. The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms. Trends Immunol. 2005, 26:485-495.
    • (2005) Trends Immunol. , vol.26 , pp. 485-495
    • Engelhardt, B.1    Ransohoff, R.M.2
  • 16
    • 2142645808 scopus 로고    scopus 로고
    • Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7
    • Fantini M.C., Becker C., Monteleone G., Pallone F., Galle P.R., Neurath M.F. Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7. J. Immunol. 2004, 172:5149-5153.
    • (2004) J. Immunol. , vol.172 , pp. 5149-5153
    • Fantini, M.C.1    Becker, C.2    Monteleone, G.3    Pallone, F.4    Galle, P.R.5    Neurath, M.F.6
  • 17
    • 0024408824 scopus 로고
    • Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
    • Fiorentino D.F., Bond M.W., Mosmann T.R. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J. Exp. Med. 1989, 170:2081-2095.
    • (1989) J. Exp. Med. , vol.170 , pp. 2081-2095
    • Fiorentino, D.F.1    Bond, M.W.2    Mosmann, T.R.3
  • 18
    • 0036848969 scopus 로고    scopus 로고
    • Microglia in human immunodeficiency virus-associated neurodegeneration
    • Garden G.A. Microglia in human immunodeficiency virus-associated neurodegeneration. Glia 2002, 40:240-251.
    • (2002) Glia , vol.40 , pp. 240-251
    • Garden, G.A.1
  • 19
    • 0034723366 scopus 로고    scopus 로고
    • HIV infection and dementia
    • Gartner S. HIV infection and dementia. Science 2000, 287:602-604.
    • (2000) Science , vol.287 , pp. 602-604
    • Gartner, S.1
  • 21
    • 33750691006 scopus 로고    scopus 로고
    • The role of regulatory T cells in the control of natural killer cells: relevance during tumor progression
    • Ghiringhelli F., Menard C., Martin F., Zitvogel L. The role of regulatory T cells in the control of natural killer cells: relevance during tumor progression. Immunol. Rev. 2006, 214:229-238.
    • (2006) Immunol. Rev. , vol.214 , pp. 229-238
    • Ghiringhelli, F.1    Menard, C.2    Martin, F.3    Zitvogel, L.4
  • 25
    • 3242801352 scopus 로고    scopus 로고
    • Large-scale in vitro expansion of polyclonal human CD4(+)CD25 high regulatory T cells
    • Hoffmann P., Eder R., Kunz-Schughart L.A., Andreesen R., Edinger M. Large-scale in vitro expansion of polyclonal human CD4(+)CD25 high regulatory T cells. Blood 2004, 104:895-903.
    • (2004) Blood , vol.104 , pp. 895-903
    • Hoffmann, P.1    Eder, R.2    Kunz-Schughart, L.A.3    Andreesen, R.4    Edinger, M.5
  • 26
    • 0037025943 scopus 로고    scopus 로고
    • Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation
    • Hoffmann P., Ermann J., Edinger M., Fathman C.G., Strober S. Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J. Exp. Med. 2002, 196:389-399.
    • (2002) J. Exp. Med. , vol.196 , pp. 389-399
    • Hoffmann, P.1    Ermann, J.2    Edinger, M.3    Fathman, C.G.4    Strober, S.5
  • 27
    • 0030483487 scopus 로고    scopus 로고
    • AIDS dementia and HIV-1-induced neurotoxicity: possible pathogenic associations and mechanisms
    • Kolson D.L., Pomerantz R.J. AIDS dementia and HIV-1-induced neurotoxicity: possible pathogenic associations and mechanisms. J. Biomed. Sci. 1996, 3:389-414.
    • (1996) J. Biomed. Sci. , vol.3 , pp. 389-414
    • Kolson, D.L.1    Pomerantz, R.J.2
  • 28
    • 60549115770 scopus 로고    scopus 로고
    • Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity
    • Komatsu N., Mariotti-Ferrandiz M.E., Wang Y., Malissen B., Waldmann H., Hori S. Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity. Proc. Natl Acad. Sci. USA 2009, 106:1903-1908.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 1903-1908
    • Komatsu, N.1    Mariotti-Ferrandiz, M.E.2    Wang, Y.3    Malissen, B.4    Waldmann, H.5    Hori, S.6
  • 29
    • 0028075890 scopus 로고
    • Interference of interleukin-10 with human immunodeficiency virus type 1 replication in primary monocyte-derived macrophages
    • Kootstra N.A., van 't Wout A., Huisman H.G., Miedema F., Schuitemaker H. Interference of interleukin-10 with human immunodeficiency virus type 1 replication in primary monocyte-derived macrophages. J. Virol. 1994, 68:6967-6975.
    • (1994) J. Virol. , vol.68 , pp. 6967-6975
    • Kootstra, N.A.1    van 't Wout, A.2    Huisman, H.G.3    Miedema, F.4    Schuitemaker, H.5
  • 31
    • 34447540064 scopus 로고    scopus 로고
    • Neurologic complications of HIV disease and their treatment
    • Letendre S., Ances B., Gibson S., Ellis R.J. Neurologic complications of HIV disease and their treatment. Top. HIV Med. 2007, 15:32-39.
    • (2007) Top. HIV Med. , vol.15 , pp. 32-39
    • Letendre, S.1    Ances, B.2    Gibson, S.3    Ellis, R.J.4
  • 32
    • 0035806323 scopus 로고    scopus 로고
    • Human cd25(+)cd4(+) T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
    • Levings M.K., Sangregorio R., Roncarolo M.G. Human cd25(+)cd4(+) T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J. Exp. Med. 2001, 193:1295-1302.
    • (2001) J. Exp. Med. , vol.193 , pp. 1295-1302
    • Levings, M.K.1    Sangregorio, R.2    Roncarolo, M.G.3
  • 33
    • 65449173545 scopus 로고    scopus 로고
    • Neuromodulatory activities of CD4+CD25+ regulatory T cells in a murine model of HIV-1-associated neurodegeneration
    • Liu J., Gong N., Huang X., Reynolds A.D., Mosley R.L., Gendelman H.E. Neuromodulatory activities of CD4+CD25+ regulatory T cells in a murine model of HIV-1-associated neurodegeneration. J. Immunol. 2009, 182:3855-3865.
    • (2009) J. Immunol. , vol.182 , pp. 3855-3865
    • Liu, J.1    Gong, N.2    Huang, X.3    Reynolds, A.D.4    Mosley, R.L.5    Gendelman, H.E.6
  • 34
    • 14944371830 scopus 로고    scopus 로고
    • Immunotherapy of autoimmune encephalomyelitis with redirected CD4+CD25+ T lymphocytes
    • Mekala D.J., Geiger T.L. Immunotherapy of autoimmune encephalomyelitis with redirected CD4+CD25+ T lymphocytes. Blood 2005, 105:2090-2092.
    • (2005) Blood , vol.105 , pp. 2090-2092
    • Mekala, D.J.1    Geiger, T.L.2
  • 36
    • 0035801335 scopus 로고    scopus 로고
    • Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
    • Nakamura K., Kitani A., Strober W. Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J. Exp. Med. 2001, 194:629-644.
    • (2001) J. Exp. Med. , vol.194 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 37
    • 1642321982 scopus 로고    scopus 로고
    • IL-2, regulatory T cells, and tolerance
    • Nelson B.H. IL-2, regulatory T cells, and tolerance. J. Immunol. 2004, 172:3983-3988.
    • (2004) J. Immunol. , vol.172 , pp. 3983-3988
    • Nelson, B.H.1
  • 38
    • 33644845532 scopus 로고    scopus 로고
    • Adjunctive therapies for HIV-1 associated neurologic disease
    • Perry S.W., Norman J.P., Gelbard H.A. Adjunctive therapies for HIV-1 associated neurologic disease. Neurotox. Res. 2005, 8:161-166.
    • (2005) Neurotox. Res. , vol.8 , pp. 161-166
    • Perry, S.W.1    Norman, J.P.2    Gelbard, H.A.3
  • 41
    • 0034843021 scopus 로고    scopus 로고
    • Immunomodulators as adjunctive therapy for HIV-1 infection
    • Pett S.L., Emery S. Immunomodulators as adjunctive therapy for HIV-1 infection. J. Clin. Virol. 2001, 22:289-295.
    • (2001) J. Clin. Virol. , vol.22 , pp. 289-295
    • Pett, S.L.1    Emery, S.2
  • 42
    • 0037090141 scopus 로고    scopus 로고
    • Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis
    • Poluektova L.Y., Munn D.H., Persidsky Y., Gendelman H.E. Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis. J. Immunol. 2002, 168:3941-3949.
    • (2002) J. Immunol. , vol.168 , pp. 3941-3949
    • Poluektova, L.Y.1    Munn, D.H.2    Persidsky, Y.3    Gendelman, H.E.4
  • 44
    • 64249169415 scopus 로고    scopus 로고
    • Nitrated {alpha}-synuclein-induced alterations in microglial immunity are regulated by CD4+ T cell subsets
    • Reynolds A.D., Stone D.K., Mosley R.L., Gendelman H.E. Nitrated {alpha}-synuclein-induced alterations in microglial immunity are regulated by CD4+ T cell subsets. J. Immunol. 2009, 182:4137-4149.
    • (2009) J. Immunol. , vol.182 , pp. 4137-4149
    • Reynolds, A.D.1    Stone, D.K.2    Mosley, R.L.3    Gendelman, H.E.4
  • 45
    • 67650351515 scopus 로고    scopus 로고
    • Proteomic studies of nitrated alpha-synuclein microglia regulation by CD4+CD25+ T cells
    • Reynolds A.D., Stone D.K., Mosley R.L., Gendelman H.E. Proteomic studies of nitrated alpha-synuclein microglia regulation by CD4+CD25+ T cells. J. Proteome Res. 2009, 8:3497-3511.
    • (2009) J. Proteome Res. , vol.8 , pp. 3497-3511
    • Reynolds, A.D.1    Stone, D.K.2    Mosley, R.L.3    Gendelman, H.E.4
  • 46
    • 34548463435 scopus 로고    scopus 로고
    • Expanded murine regulatory T cells: analysis of phenotype and function in contact hypersensitivity reactions
    • Ring S., Thome M., Pretsch L., Enk A.H., Mahnke K. Expanded murine regulatory T cells: analysis of phenotype and function in contact hypersensitivity reactions. J. Immunol. Methods 2007, 326:10-21.
    • (2007) J. Immunol. Methods , vol.326 , pp. 10-21
    • Ring, S.1    Thome, M.2    Pretsch, L.3    Enk, A.H.4    Mahnke, K.5
  • 49
    • 34547214205 scopus 로고    scopus 로고
    • Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans
    • Roncarolo M.G., Battaglia M. Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans. Nat. Rev. Immunol. 2007, 7:585-598.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 585-598
    • Roncarolo, M.G.1    Battaglia, M.2
  • 50
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi S. Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 2004, 22:531-562.
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 52
    • 33746369415 scopus 로고    scopus 로고
    • Regulatory T-cell physiology and application to treat autoimmunity
    • Tang Q., Bluestone J.A. Regulatory T-cell physiology and application to treat autoimmunity. Immunol. Rev. 2006, 212:217-237.
    • (2006) Immunol. Rev. , vol.212 , pp. 217-237
    • Tang, Q.1    Bluestone, J.A.2
  • 55
    • 2942692039 scopus 로고    scopus 로고
    • CD25+CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes
    • Tarbell K.V., Yamazaki S., Olson K., Toy P., Steinman R.M. CD25+CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J. Exp. Med. 2004, 199:1467-1477.
    • (2004) J. Exp. Med. , vol.199 , pp. 1467-1477
    • Tarbell, K.V.1    Yamazaki, S.2    Olson, K.3    Toy, P.4    Steinman, R.M.5
  • 56
    • 0031821875 scopus 로고    scopus 로고
    • CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • Thornton A.M., Shevach E.M. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 1998, 188:287-296.
    • (1998) J. Exp. Med. , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 57
    • 0346690399 scopus 로고    scopus 로고
    • Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia
    • Trenado A., Charlotte F., Fisson S., Yagello M., Klatzmann D., Salomon B.L., Cohen J.L. Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia. J. Clin. Invest. 2003, 112:1688-1696.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1688-1696
    • Trenado, A.1    Charlotte, F.2    Fisson, S.3    Yagello, M.4    Klatzmann, D.5    Salomon, B.L.6    Cohen, J.L.7
  • 58
    • 33846086980 scopus 로고    scopus 로고
    • Transforming growth factor-beta: innately bipolar
    • Wahl S.M. Transforming growth factor-beta: innately bipolar. Curr. Opin. Immunol. 2007, 19:55-62.
    • (2007) Curr. Opin. Immunol. , vol.19 , pp. 55-62
    • Wahl, S.M.1
  • 59
    • 35748966479 scopus 로고    scopus 로고
    • 'Yin-Yang' functions of transforming growth factor-beta and T regulatory cells in immune regulation
    • Wan Y.Y., Flavell R.A. 'Yin-Yang' functions of transforming growth factor-beta and T regulatory cells in immune regulation. Immunol. Rev. 2007, 220:199-213.
    • (2007) Immunol. Rev. , vol.220 , pp. 199-213
    • Wan, Y.Y.1    Flavell, R.A.2
  • 60
    • 56649118964 scopus 로고    scopus 로고
    • TGF-beta and regulatory T cell in immunity and autoimmunity
    • Wan Y.Y., Flavell R.A. TGF-beta and regulatory T cell in immunity and autoimmunity. J. Clin. Immunol. 2008, 28:647-659.
    • (2008) J. Clin. Immunol. , vol.28 , pp. 647-659
    • Wan, Y.Y.1    Flavell, R.A.2
  • 61
    • 1642497640 scopus 로고    scopus 로고
    • Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy
    • Wang H.Y., Lee D.A., Peng G., Guo Z., Li Y., Kiniwa Y., Shevach E.M., Wang R.F. Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy. Immunity 2004, 20:107-118.
    • (2004) Immunity , vol.20 , pp. 107-118
    • Wang, H.Y.1    Lee, D.A.2    Peng, G.3    Guo, Z.4    Li, Y.5    Kiniwa, Y.6    Shevach, E.M.7    Wang, R.F.8


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